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Panagiotis Fidias, MD

Publications

  • Korst RJ, Bezjak A, Blackmon S, Choi N, Fidias P, Liu G, Marx A, Wright C, Mock S, Rutledge JR, Keshavjee S.Neoadjuvant chemoradiotherapy for locally advanced thymic tumors: a phase II, multi-institutional clinical trial.J Thorac Cardiovasc Surg. 2014 Jan;147(1):36-44, 46.e1.
    24139613
  • Lee MS, Mamon HJ, Hong TS, Choi NC, Fidias PM, Kwak EL, Meyerhardt JA, Ryan DP, Bueno R, Donahue DM, Jaklitsch MT, Lanuti M, Rattner DW, Fuchs CS, Enzinger PC.Preoperative cetuximab, irinotecan, Cisplatin, and radiation therapy for patients with locally advanced esophageal cancer.Oncologist. 2013;18(3):281-7.
    23429739
  • Choi NC, Chun TT, Niemierko A, Ancukiewicz M, Fidias PM, Kradin RL, Mathisen DJ, Lynch TJ, Fischman AJ.Potential of (18)F-FDG PET toward personalized radiotherapy or chemoradiotherapy in lung cancer.Eur J Nucl Med Mol Imaging. 2013 Feb 12.
    23400506
  • Camidge DR, Bang YJ, Kwak EL, Iafrate AJ, Varella-Garcia M, Fox SB, Riely GJ, Solomon B, Ou SH, Kim DW, Salgia R, Fidias P, Engelman JA, Gandhi L, Jänne PA, Costa DB, Shapiro GI, Lorusso P, Ruffner K, Stephenson P, Tang Y, Wilner K, Clark JW, Shaw AT.Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study.Lancet Oncol. 2012 Oct;13(10):1011-9.
    22954507
  • Goldberg SB, Supko JG, Neal JW, Muzikansky A, Digumarthy S, Fidias P, Temel JS, Heist RS, Shaw AT, McCarthy PO, Lynch TJ, Sharma S, Settleman JE, Sequist LV.A phase I study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancer.J Thorac Oncol. 2012 Oct;7(10):1602-8.
    22878749
  • Sequist LV, Waltman BA, Dias-Santagata D, Digumarthy S, Turke AB, Fidias P, Bergethon K, Shaw AT, Gettinger S, Cosper AK, Akhavanfard S, Heist RS, Temel J, Christensen JG, Wain JC, Lynch TJ, Vernovsky K, Mark EJ, Lanuti M, Iafrate AJ, Mino-Kenudson M, Engelman JA.Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors.Sci Transl Med. 2011 Mar 23;3(75):75ra26.
    21430269
  • Chan JA, Blaszkowsky LS, Enzinger PC, Ryan DP, Abrams TA, Zhu AX, Temel JS, Schrag D, Bhargava P, Meyerhardt JA, Wolpin BM, Fidias P, Zheng H, Florio S, Regan E, Fuchs CS.A multicenter phase II trial of single-agent cetuximab in advanced esophageal and gastric adenocarcinoma.Ann Oncol. 2011 Jan 7.
    21217058
  • Fidias P, Novello S.Strategies for prolonged therapy in patients with advanced non-small-cell lung cancer.J Clin Oncol. 2010 Dec 1;28(34):5116-23. Review.
    21041704
  • Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, Maki RG, Ou SH, Dezube BJ, Jänne PA, Costa DB, Varella-Garcia M, Kim WH, Lynch TJ, Fidias P, Stubbs H, Engelman JA, Sequist LV, Tan W, Gandhi L, Mino-Kenudson M, Wei GC, Shreeve SM, Ratain MJ, Settleman J, Christensen JG, Haber DA, Wilner K, Salgia R, Shapiro GI, Clark JW, Iafrate AJ.Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.N Engl J Med. 2010 Oct 28;363(18):1693-703.
    20979469
  • Neal JW, Heist RS, Fidias P, Temel JS, Huberman M, Marcoux JP, Muzikansky A, Lynch TJ, Sequist LV.Cetuximab Monotherapy in Patients with Advanced Non-small Cell Lung Cancer After Prior Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy.J Thorac Oncol. 2010 Nov;5(11):1855-8.
    20975380
  • Heist RS, Fain J, Chinnasami B, Khan W, Molina JR, Sequist LV, Temel JS, Fidias P, Brainerd V, Leopold L, Lynch TJ.Phase I/II study of AT-101 with topotecan in relapsed and refractory small cell lung cancer.J Thorac Oncol. 2010 Oct;5(10):1637-43.
    20808253
  • Sequist LV, Fidias PM, Temel JS, Kolevska T, Rabin MS, Boccia RV, Burris HA, Belt RJ, Huberman MS, Melnyk O, Mills GM, Englund CW, Caldwell DC, Keck JG, Meng L, Jones M, Brown GL, Edelman MJ, Lynch TJ.Phase 1-2a multicenter dose-ranging study of canfosfamide in combination with carboplatin and paclitaxel as first-line therapy for patients with advanced non-small cell lung cancer.J Thorac Oncol. 2009 Nov;4(11):1389-96.
    19701107
  • Fidias P, Pennell NA, Boral AL, Shapiro GI, Skarin AT, Eder JP, Kwoh TJ, Geary RS, Johnson BE, Lynch TJ, Supko JG.Phase I study of the c-raf-1 antisense oligonucleotide ISIS 5132 in combination with carboplatin and paclitaxel in patients with previously untreated, advanced non-small cell lung cancer.J Thorac Oncol. 2009 Sep;4(9):1156-62.
    19704336
  • Sequist LV, Fidias P, Heist RS, Ostler P, Muzikansky A, Lynch TJ.Brief report of biweekly pemetrexed and gemcitabine in elderly patients with non-small cell lung cancer.J Thorac Oncol. 2009 Sep;4(9):1170-3.
    19704338
  • Ettinger DS,Agulnik M,Cristea M,Eaton K,Fidias PM,Gockerman JP,Hameed O,Handorf C,Harris EI,Jacobs CD,Javle M,Khushalani NI,Kvols L,Lenzi R,Lewis NL,Rashid A,Saltz L,Shulman LN,Zager JS,Zhen W.Occult primary.J Natl Compr Canc Netw. 2008 Nov;6(10):1026-60. Review.
    19176200
  • Heist RS,Fidias P,Huberman M,Ardman B,Sequist LV,Temel JS,Lynch TJ.A phase II study of oxaliplatin, pemetrexed, and bevacizumab in previously treated advanced non-small cell lung cancer.J Thorac Oncol. 2008 Oct;3(10):1153-8.
    18827612
  • Janne PA, Simon GR, Langer CJ, Taub RN, Dowlati A, Fidias P, Monberg M, Obasaju C, Kindler H.Phase II trial of pemetrexed and gemcitabine in chemotherapy-naive malignant pleural mesothelioma.J Clin Oncol. 2008 Mar 20;26(9):1465-71.
    18349397
  • Pennell NA, Daniels GH, Haddad RI, Ross DS, Evans T, Wirth LJ, Fidias PH, Temel JS, Gurubhagavatula S, Heist RS, Clark JR, Lynch TJ.A Phase II Study of Gefitinib in Patients with Advanced Thyroid Cancer.Thyroid. 2008 Mar;18(3):317-23.
    17985985
  • Wright CD, Choi NC, Wain JC, Mathisen DJ, Lynch TJ, Fidias P.Induction chemoradiotherapy followed by resection for locally advanced Masaoka stage III and IVA thymic tumors.Ann Thorac Surg. 2008 Feb;85(2):385-9.
    18222230
  • Bradbury PA, Heist RS, Kulke MH, Zhou W, Marshall AL, Miller DP, Su L, Park S, Temel J, Fidias P, Sequist L, Lynch TJ, Wain JC, Shepherd FA, Christiani DC, Liu G.A rapid outcomes ascertainment system improves the quality of prognostic and pharmacogenetic outcomes from observational studies.Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):204-11.
    18199725
  • Oxnard GR, Fidias P, Muzikansky A, Sequist LV.Non-small cell lung cancer in octogenarians: treatment practices and preferences.J Thorac Oncol. 2007 Nov;2(11):1029-35.
    17975495
  • Temel JS, Jackson VA, Billings JA, Dahlin C, Block SD, Buss MK, Ostler P, Fidias P, Muzikansky A, Greer JA, Pirl WF, Lynch TJ.Phase II study: integrated palliative care in newly diagnosed advanced non-small-cell lung cancer patients.J Clin Oncol. 2007 Jun 10;25(17):2377-82.
    17557950
  • Wright CD, Fidias P, Choi NC, Shepard JA, Hasserjian RP.Case records of the Massachusetts General Hospital. Case 16-2007. A 61-year-old man with a mediastinal mass.N Engl J Med. 2007 May 24;356(21):2185-93.
    17522403
  • Sequist LV, Joshi VA, Jnne PA, Muzikansky A, Fidias P, Meyerson M, Haber DA, Kucherlapati R, Johnson BE, Lynch TJ.Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing.Oncologist. 2007 Jan;12(1):90-8.
    17285735
  • Jackman DM, Yeap BY, Lindeman NI, Fidias P, Rabin MS, Temel J, Skarin AT, Meyerson M, Holmes AJ, Borras AM, Freidlin B, Ostler PA, Lucca J, Lynch TJ, Johnson BE, Jnne PA.Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age treated with erlotinib for advanced non-small-cell lung cancer.J Clin Oncol. 2007 Mar 1;25(7):760-6.
    17228019
  • Ryan DP, O'Neil BH, Supko JG, Rocha Lima CM, Dees EC, Appleman LJ, Clark J, Fidias P, Orlowski RZ, Kashala O, Eder JP, Cusack JC.A Phase I study of bortezomib plus irinotecan in patients with advanced solid tumors.Cancer. 2006 Dec 1;107(11):2688-97.
    17075878
  • Fanucchi MP, Fossella FV, Belt R, Natale R, Fidias P, Carbone DP, Govindan R, Raez LE, Robert F, Ribeiro M, Akerley W, Kelly K, Limentani SA, Crawford J, Reimers HJ, Axelrod R, Kashala O, Sheng S, Schiller JH.Randomized phase II study of bortezomib alone and bortezomib in combination with docetaxel in previously treated advanced non-small-cell lung cancer.J Clin Oncol. 2006 Nov 1;24(31):5025-33.
    17075122
  • Ryan DP, Appleman LJ, Lynch T, Supko JG, Fidias P, Clark JW, Fishman M, Zhu AX, Enzinger PC, Kashala O, Cusack J, Eder JP.Phase I clinical trial of bortezomib in combination with gemcitabine in patients with advanced solid tumors.Cancer. 2006 Nov 15;107(10):2482-9.
    17036355
  • Sequist LV, Joshi VA, Jnne PA, Bell DW, Fidias P, Lindeman NI, Louis DN, Lee JC, Mark EJ, Longtine J, Verlander P, Kucherlapati R, Meyerson M, Haber DA, Johnson BE, Lynch TJ.Epidermal growth factor receptor mutation testing in the care of lung cancer patients.Clin Cancer Res. 2006 Jul 15;12(14):4403s-8s. Review.
    16857818
  • Belani CP, Pereira JR, von Pawel J, Pluzanska A, Gorbounova V, Kaukel E, Mattson KV, Ramlau R, Szczesna A, Fidias P, Millward M, Fossella F,.Effect of chemotherapy for advanced non-small cell lung cancer on patients' quality of life A randomized controlled trial.Lung Cancer. 2006 Aug;53(2):231-9.
    16787687
  • Kulke MH, Muzikansky A, Clark J, Enzinger PC, Fidias P, Kinsella K, Michelini A, Fuchs CS.A Phase II trial of vinorelbine in patients with advanced gastroesophageal adenocarcinoma.Cancer Invest. 2006 Jun-Jul;24(4):346-50.
    16777685
  • Roof KS, Coen J, Lynch TJ, Wright C, Fidias P, Willett CG, Choi NC.Concurrent cisplatin, 5-FU, paclitaxel, and radiation therapy in patients with locally advanced esophageal cancer.Int J Radiat Oncol Biol Phys. 2006 Jul 15;65(4):1120-8.
    16730135
  • Sequist LV, Fidias P.Treatment of advanced non-small cell lung cancer in the elderly.Semin Respir Crit Care Med. 2005 Jun;26(3):289-97.
    16052430
  • Jnne PA, Gurubhagavatula S, Yeap BY, Lucca J, Ostler P, Skarin AT, Fidias P, Lynch TJ, Johnson BE.Outcomes of patients with advanced non-small cell lung cancer treated with gefitinib (ZD1839, "Iressa") on an expanded access study.Lung Cancer. 2004 May;44(2):221-30.
    15084387
  • Sharma A, Fidias P, Hayman LA, Loomis SL, Taber KH, Aquino SL.Patterns of lymphadenopathy in thoracic malignancies.Radiographics. 2004 Mar-Apr;24(2):419-34.
    15026591
  • Fidias P, Grossbard M, Lynch TJ.A phase II study of the immunotoxin N901-blocked ricin in small-cell lung cancer.Clin Lung Cancer. 2002 Feb;3(3):219-22.
    14662047
  • Roof KS, Fidias P, Lynch TJ, Choi NC.Radiation dose intensification in limited-stage small-cell lung cancer.Clin Lung Cancer. 2003 May;4(6):339-46.
    14599300
  • Roof KS, Fidias P, Lynch TJ, Ancukiewicz M, Choi NC.Radiation dose escalation in limited-stage small-cell lung cancer.Int J Radiat Oncol Biol Phys. 2003 Nov 1;57(3):701-8.
    14529774
  • Fossella F, Pereira JR, von Pawel J, Pluzanska A, Gorbounova V, Kaukel E, Mattson KV, Ramlau R, Szczesna A, Fidias P, Millward M, Belani CP.Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group.J Clin Oncol. 2003 Aug 15;21(16):3016-24.
    12837811
  • Wirth LJ, Lucca J, Ostler P, Fidias P, Lynch C, Jnne PA, Herbst RS, Johnson BE, Sugarbaker DJ, Mathisen DJ, Lukanich JM, Choi NC, Berman SM, Skarin AT.Induction docetaxel and carboplatin followed by weekly docetaxel and carboplatin with concurrent radiotherapy, then surgery in stage III non-small cell lung cancer: a Phase I study.Clin Cancer Res. 2003 May;9(5):1698-704.
    12738723
  • Salgia R, Lynch T, Skarin A, Lucca J, Lynch C, Jung K, Hodi FS, Jaklitsch M, Mentzer S, Swanson S, Lukanich J, Bueno R, Wain J, Mathisen D, Wright C, Fidias P, Donahue D, Clift S, Hardy S, Neuberg D, Mulligan R, Webb I, Sugarbaker D, Mihm M, Dranoff G.Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma.J Clin Oncol. 2003 Feb 15;21(4):624-30.
    12586798
  • Choi NC, Fischman AJ, Niemierko A, Ryu JS, Lynch T, Wain J, Wright C, Fidias P, Mathisen D.Dose-response relationship between probability of pathologic tumor control and glucose metabolic rate measured with FDG PET after preoperative chemoradiotherapy in locally advanced non-small-cell lung cancer.Int J Radiat Oncol Biol Phys. 2002 Nov 15;54(4):1024-35.
    12419428
  • Fidias P, Supko JG, Martins R, Boral A, Carey R, Grossbard M, Shapiro G, Ostler P, Lucca J, Johnson BE, Skarin A, Lynch TJ.A phase II study of weekly paclitaxel in elderly patients with advanced non-small cell lung cancer.Clin Cancer Res. 2001 Dec;7(12):3942-9.
    11751486
  • Fidias P, Spiro I, Sobczak ML, Nielsen GP, Ruffolo EF, Mankin H, Suit HD, Harmon DC.Long-term results of combined modality therapy in primary bone lymphomas.Int J Radiat Oncol Biol Phys. 1999 Dec 1;45(5):1213-8.
    10613315
  • Fidias P, Chabner BA, Grossbard ML.Purine Analogs for the Treatment of Low-Grade Lymphoproliferative Disorders.Oncologist. 1996;1(3):125-139.
    10387979
  • Grossbard ML, Fidias P, Kinsella J, O'Toole J, Lambert JM, Blattler WA, Esseltine D, Braman G, Nadler LM, Anderson KC.Anti-B4-blocked ricin: a phase II trial of 7 day continuous infusion in patients with multiple myeloma.Br J Haematol. 1998 Jul;102(2):509-15.
    9695966
  • Johnston PG, Takimoto CH, Grem JL, Fidias P, Grossbard ML, Chabner BA, Allegra CJ, Chu E.Antimetabolites.Cancer Chemother Biol Response Modif. 1997;17:1-39.
    9551206
  • Fidias P, Fan CM, McGovern FJ, Wright CD, Kaufman J, Grossbard ML.Intracaval extension of germ cell carcinoma: diagnosis via endovascular biopsy and a review of the literature.Eur Urol. 1997;31(3):376-9.
    9129935
  • Fidias P, Wright C, Harris NL, Urba W, Grossbard ML.Primary tracheal non-Hodgkin's lymphoma. A case report and review of the literature.Cancer. 1996 Jun 1;77(11):2332-8.
    8635104
  • Wilkes JD, Fidias P, Vaickus L, Perez RP.Malignancy-related pericardial effusion. 127 cases from the Roswell Park Cancer Institute.Cancer. 1995 Oct 15;76(8):1377-87.
    8620412
  • Grossbard ML, Fidias P.Prospects for immunotoxin therapy of non-Hodgkin's lymphoma.Clin Immunol Immunopathol. 1995 Aug;76(2):107-14.
    7614729
  • Fidias P, Carey RW, Grossbard ML.Non-Hodgkin's lymphoma presenting with biliary tract obstruction. A discussion of seven patients and a review of the literature.Cancer. 1995 Apr 1;75(7):1669-77.
    8826926