Beow Yong Yeap, ScD

Publications

• Lutton BV, Cho PS, Hirsh EL, Ferguson KK, Teague AG, Hanekamp JS, Chi N, Goldman SN, Messina DJ, Houser S, Yeap BY, Popma SH, Sachs DH, Huang CA.Approaches to avoid immune responses induced by repeated subcutaneous injections of allogeneic umbilical cord
  21451445
• Childs SK, Kozak KR, Friedmann AM, Yeap BY, Adams J, Macdonald SM, Liebsch NJ, Tarbell NJ, Yock TI.Proton Radiotherapy for Parameningeal Rhabdomyosarcoma: Clinical Outcomes and Late Effects.Int J Radiat Oncol Biol Phys. 2011 Mar 4.
  21377294
• De Rienzo A, Dong L, Yeap BY, Jensen RV, Richards WG, Gordon GJ, Sugarbaker DJ, Bueno R.Fine-needle aspiration biopsies for gene expression ratio-based diagnostic and prognostic tests in malignant pleural mesothelioma.Clin Cancer Res. 2011 Jan 15;17(2):31
  21088255
• Hong TS, Ryan DP, Blaszkowsky LS, Mamon HJ, Kwak EL, Mino-Kenudson M, Adams J, Yeap B, Winrich B, Delaney TF, Fernandez-Del Castillo C.Phase I Study of Preoperative Short-Course Chemoradiation with Proton Beam Therapy and Capecitabine for Resectable Pancr
  20421151
• Heon S, Yeap BY, Britt GJ, Costa DB, Rabin MS, Jackman DM, Johnson BE.Development of central nervous system metastases in patients with advanced non-small cell lung cancer and somatic EGFR mutations treated with gefitinib or erlotinib.Clin Cancer Res. 201
  21030498
• Nishino M, Jackman DM, Hatabu H, Yeap BY, Cioffredi LA, Yap JT, Jänne PA, Johnson BE, Van den Abbeele AD.New Response Evaluation Criteria in Solid Tumors (RECIST) guidelines for advanced non-small cell lung cancer: comparison with original RECIST and imp
  20729419
• Ballen KK, Cutler C, Yeap BY, McAfee SL, Dey BR, Attar EC, Chen YB, Haspel RL, Liney D, Koreth J, Ho V, Alyea EP, Soiffer RJ, Spitzer TR, Antin JH.Donor Derived Second Hematologic Malignancies after Cord Blood Transplantation.Biol Blood Marrow Transplant.
  20178854
• Sholl LM, Barletta JA, Yeap BY, Chirieac LR, Hornick JL.Sox2 protein expression is an independent poor prognostic indicator in stage I lung adenocarcinoma.Am J Surg Pathol. 2010 Aug;34(8):1193-8.
  20631605
• Benedettini E, Sholl LM, Peyton M, Reilly J, Ware C, Davis L, Vena N, Bailey D, Yeap BY, Fiorentino M, Ligon AH, Pan BS, Richon V, Minna JD, Gazdar AF, Draetta G, Bosari S, Chirieac LR, Lutterbach B, Loda M.Met Activation in Non-Small Cell Lung Cancer Is
  20489150
• Yeo WL, Riely GJ, Yeap BY, Lau MW, Warner JL, Bodio K, Huberman MS, Kris MG, Tenen DG, Pao W, Kobayashi S, Costa DB.Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with EGFR mutations.J Thorac Oncol. 2010 Jul;5(7):1048-53.
  20512075
• Sholl LM, Xiao Y, Joshi V, Yeap BY, Cioffredi LA, Jackman DM, Lee C, Jänne PA, Lindeman NI.EGFR mutation is a better predictor of response to tyrosine kinase inhibitors in non-small cell lung carcinoma than FISH, CISH, and immunohistochemistry.Am J Clin
  20472851
• Duran-Struuck R, Cho PS, Teague AG, Fishman B, Fishman AS, Hanekamp JS, Moran SG, Wikiel KJ, Ferguson KK, Lo DP, Duggan M, Arn JS, Billiter B, Horner B, Houser S, Yeap BY, Westmoreland SV, Spitzer TR, McMorrow IM, Sachs DH, Bronson RT, Huang CA.Myelogenou
  20079939
• Hartman ML, Esposito JM, Yeap BY, Sugarbaker DJ.Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma.J Thorac Cardiovasc Surg. 2010 May;139(5):1233-40.
  19853261
• Richards WG, Godleski JJ, Yeap BY, Corson JM, Chirieac LR, Zellos L, Mujoomdar A, Jaklitsch MT, Bueno R, Sugarbaker DJ.Proposed adjustments to pathologic staging of epithelial malignant pleural mesothelioma based on analysis of 354 cases.Cancer. 2010 Mar
  20108310
• Barletta JA,Perner S,Iafrate AJ,Yeap BY,Weir BA,Johnson LA,Johnson BE,Meyerson M,Rubin MA,Travis WD,Loda M,Chirieac LR.Clinical Significance of TTF-1 Protein Expression and TTF-1 Gene Amplification in Lung Adenocarcinoma.J Cell Mol Med. 2009 Aug;13(8B):19
  19040416
• Turke AB, Zejnullahu K, Wu YL, Song Y, Dias-Santagata D, Lifshits E, Toschi L, Rogers A, Mok T, Sequist L, Lindeman NI, Murphy C, Akhavanfard S, Yeap BY, Xiao Y, Capelletti M, Iafrate AJ, Lee C, Christensen JG, Engelman JA, Jänne PA.Preexistence and clon
  20129249
• Barletta JA, Yeap BY, Chirieac LR.Prognostic significance of grading in lung adenocarcinoma.Cancer. 2010 Feb 1;116(3):659-69.
  20014400
• Faber AC, Li D, Song Y, Liang MC, Yeap BY, Bronson RT, Lifshits E, Chen Z, Maira SM, García-Echeverría C, Wong KK, Engelman JA.Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition.Proc Natl Acad Sci U S A. 2009
  19850869
• Sholl LM, Yeap BY, Iafrate AJ, Holmes-Tisch AJ, Chou YP, Wu MT, Goan YG, Su L, Benedettini E, Yu J, Loda M, Jänne PA, Christiani DC, Chirieac LR.Lung adenocarcinoma with EGFR amplification has distinct clinicopathologic and molecular features in never-sm
  19826035
• Sholl LM, Yeap BY, Iafrate AJ, Holmes-Tisch AJ, Chou YP, Wu MT, Goan YG, Su L, Benedettini E, Yu J, Loda M, Jänne PA, Christiani DC, Chirieac LR.Lung adenocarcinoma with EGFR amplification has distinct clinicopathologic and molecular features in never-sm
• Shaw AT, Yeap BY, Mino-Kenudson M, Digumarthy SR, Costa DB, Heist RS, Solomon B, Stubbs H, Admane S, McDermott U, Settleman J, Kobayashi S, Mark EJ, Rodig SJ, Chirieac LR, Kwak EL, Lynch TJ, Iafrate AJ.Clinical Features and Outcome of Patients With Non-Sm
  19667264
• Pirl WF, Greer J, Temel JS, Yeap BY, Gilman SE.Major Depressive Disorder in Long-Term Cancer Survivors: Analysis of the National Comorbidity Survey Replication.J Clin Oncol. 2009 Sep 1;27(25):4130-4.
  19636024
• Jackman DM, Miller VA, Cioffredi LA, Yeap BY, Jänne PA, Riely GJ, Ruiz MG, Giaccone G, Sequist LV, Johnson BE.Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients:
  19671843
• Rodig SJ, Mino-Kenudson M, Dacic S, Yeap BY, Shaw A, Barletta JA, Stubbs H, Law K, Lindeman N, Mark E, Janne PA, Lynch T, Johnson BE, Iafrate AJ, Chirieac LR.Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western
  19671850
• Hattangadi JA, Hong TS, Yeap BY, Mamon HJ.Results and patterns of failure in patients treated with adjuvant combined chemoradiation therapy for resected pancreatic adenocarcinoma.Cancer. 2009 Aug 15;115(16):3640-50.
  19514088
• Tilleman TR, Richards WG, Zellos L, Johnson BE, Jaklitsch MT, Mueller J, Yeap BY, Mujoomdar AA, Ducko CT, Bueno R, Sugarbaker DJ.Extrapleural pneumonectomy followed by intracavitary intraoperative hyperthermic cisplatin with pharmacologic cytoprotection f
  19619785
• Naumov GN,Nilsson MB,Cascone T,Briggs A,Straume O,Akslen LA,Lifshits E,Byers LA,Xu L,Wu HK,Janne P,Kobayashi S,Halmos B,Tenen D,Tang XM,Engelman J,Yeap B,Folkman J,Johnson BE,Heymach JV.Combined vascular endothelial growth factor receptor and epidermal gr
  19447865
• Gordon GJ,Dong L,Yeap BY,Richards WG,Glickman JN,Edenfield H,Mani M,Colquitt R,Maulik G,Van Oss B,Sugarbaker DJ,Bueno R.Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma.Journal of the National Cancer Institute.
  19401544
• Kuang Y,Rogers A,Yeap BY,Wang L,Makrigiorgos M,Vetrand K,Thiede S,Distel RJ,Janne PA.Noninvasive detection of EGFR T790M in gefitinib or erlotinib resistant non-small cell lung cancer.Clin Cancer Res. 2009 Apr 15;15(8):2630-6.
  19351754
• Wang H,Asavaroengchai W,Yeap BY,Wang MG,Wang S,Sykes M,Yang YG.Paradoxical effects of IFN-gamma in graft-versus-host disease reflect promotion of lymphohematopoietic graft-versus-host reactions and inhibition of epithelial tissue injury.Blood. 2009 Apr 9;
  19211507
• Delaney M,Cutler CS,Haspel RL,Yeap BY,McAfee SL,Dey BR,Attar E,Kao G,Alyea EP,Koreth J,Ho VT,Saidman S,Liney D,Sese D,Soiffer RJ,Spitzer TR,Antin JH,Ballen KK.High-resolution HLA matching in double-umbilical-cord-blood reduced-intensity transplantation in
  19159415
• Yusuf RZ, Dey B, Yeap BY, McAfee S, Attar E, Sepe PS, Dube C, Spitzer TR, Ballen KK.Autologous SCT with a dose-reduced BU and CY regimen in older patients with non-Hodgkin's lymphoma.Bone Marrow Transplant. 2009 Jan;43(1):37-42.
  18794868
• DeLaney TF,Liebsch NJ,Pedlow FX,Adams J,Dean S,Yeap BY,McManus P,Rosenberg AE,Nielsen GP,Harmon DC,Spiro IJ,Raskin KA,Suit HD,Yoon SS,Hornicek FJ.Phase II study of high-dose photon/proton radiotherapy in the management of spine sarcomas.Int J Radiat Oncol
  19095372
• Costa DB,Nguyen KS,Cho BC,Sequist LV,Jackman DM,Riely GJ,Yeap BY,Halmos B,Kim JH,Janne PA,Huberman MS,Pao W,Tenen DG,Kobayashi S.Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib.Clin Cancer Res. 2008 Nov 1;14(2
  18981003
• Saad AG,Yeap BY,Thunnissen FB,Pinkus GS,Pinkus JL,Loda M,Sugarbaker DJ,Johnson BE,Chirieac LR.Immunohistochemical markers associated with brain metastases in patients with nonsmall cell lung carcinoma.Cancer. 2008 Oct 15;113(8):2129-38.
  18720359
• Winkfield KM,Linsenmeier C,Yock TI,Grant PE,Yeap BY,Butler WE,Tarbell NJ.Surveillance of craniopharyngioma cyst growth in children treated with proton radiotherapy.Int J Radiat Oncol Biol Phys. 2009 Mar 1;73(3):716-21.
  18676089
• Koivunen JP, Kim J, Lee J, Rogers AM, Park JO, Zhao X, Naoki K, Okamoto I, Nakagawa K, Yeap BY, Meyerson M, Wong KK, Richards WG, Sugarbaker DJ, Johnson BE, Jänne PA.Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasia
  18594528
• Kerber RA,Amos CI,Yeap BY,Finkelstein DM,Thomas DC.Design considerations in a sib-pair study of linkage for susceptibility loci in cancer.BMC Med Genet. 2008;9:64.
  18616822
• Macdonald SM, Safai S, Trofimov A, Wolfgang J, Fullerton B, Yeap BY, Bortfeld T, Tarbell NJ, Yock T.Proton Radiotherapy for Childhood Ependymoma: Initial Clinical Outcomes and Dose Comparisons.Int J Radiat Oncol Biol Phys. 2008 Jul 15;71(4):979-86.
  18325681
• Haspel RL, Kao G, Yeap BY, Cutler C, Soiffer RJ, Alyea EP, Ho VT, Koreth J, Dey BR, McAfee SL, Attar EC, Spitzer T, Antin JH, Ballen KK.Preinfusion variables predict the predominant unit in the setting of reduced-intensity double cord blood transplantatio
  18037942
• Liu G, Gurubhagavatula S, Zhou W, Wang Z, Yeap BY, Asomaning K, Su L, Heist R, Lynch TJ, Christiani DC.Epidermal growth factor receptor polymorphisms and clinical outcomes in non-small-cell lung cancer patients treated with gefitinib.Pharmacogenomics J. 2
  17375033
• Allen AM, Mentzer SJ, Yeap BY, Soto R, Baldini EH, Rabin MS, Sugarbaker DJ, Bueno R.Pneumonectomy after chemoradiation: the Dana-Farber Cancer Institute/Brigham and Women's Hospital experience.Cancer. 2008 Mar 1;112(5):1106-13.
  18286507
• Gordon GJ, Mani M, Maulik G, Mukhopadhyay L, Yeap BY, Kindler HL, Salgia R, Sugarbaker DJ, Bueno R.Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma.Cancer Chemother Pharmacol. 2008 Apr;61(4):549-58.
  17522864
• Richards W, Van Oss S, Glickman J, Chirieac L, Yeap B, Dong L, Gordon G, Mercer H, Gill K, Imrich A, Bueno R, Sugarbaker D.A microaliquoting technique for precise histological annotation and optimization of cell content in frozen tissue specimens.Biotech
  17917854
• Jänne PA, von Pawel J, Cohen RB, Crino L, Butts CA, Olson SS, Eiseman IA, Chiappori AA, Yeap BY, Lenehan PF, Dasse K, Sheeran M, Bonomi PD.Multicenter, randomized, phase II trial of CI-1033, an irreversible pan-ERBB inhibitor, for previously treated advan
  17761977
• Ballen KK, Shpall EJ, Avigan D, Yeap BY, Fisher DC, McDermott K, Dey BR, Attar E, McAfee S, Konopleva M, Antin JH, Spitzer TR.Phase I trial of parathyroid hormone to facilitate stem cell mobilization.Biol Blood Marrow Transplant. 2007 Jul;13(7):838-43.
  17580262
• Liu G, Zhou W, Yeap BY, Su L, Wain JC, Poneros JM, Nishioka NS, Lynch TJ, Christiani DC.XRCC1 and XPD Polymorphisms and Esophageal Adenocarcinoma Risk.Carcinogenesis. 2007 Jun;28(6):1254-8.
  17264068
• Linden PA, Yeap BY, Chang MY, Henderson WG, Jaklitsch MT, Khuri S, Sugarbaker DJ, Bueno R.Morbidity of lung resection after prior lobectomy: results from the Veterans Affairs National Surgical Quality Improvement Program.Ann Thorac Surg. 2007 Feb;83(2):42
  17257965
• Gordon GJ, Mani M, Mukhopadhyay L, Dong L, Edenfield HR, Glickman JN, Yeap BY, Sugarbaker DJ, Bueno R.Expression patterns of inhibitor of apoptosis proteins in malignant pleural mesothelioma.J Pathol. 2007 Mar;211(4):447-54.
  17253596
• Gordon GJ, Mani M, Mukhopadhyay L, Dong L, Yeap BY, Sugarbaker DJ, Bueno R.Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma.J Pathol. 2007 Mar;211(4):439-46.
  17253597
• Jackman DM, Yeap BY, Lindeman NI, Fidias P, Rabin MS, Temel J, Skarin AT, Meyerson M, Holmes AJ, Borras AM, Freidlin B, Ostler PA, Lucca J, Lynch TJ, Johnson BE, Jänne PA.Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age tre
  17228019
• Ballen KK, Spitzer TR, Yeap BY, McAfee S, Dey BR, Attar E, Haspel R, Kao G, Liney D, Alyea E, Lee S, Cutler C, Ho V, Soiffer R, Antin JH.Double unrelated reduced-intensity umbilical cord blood transplantation in adults.Biol Blood Marrow Transplant. 2007 J
  17222756
• Engelman JA, Mukohara T, Zejnullahu K, Lifshits E, Borrás AM, Gale CM, Naumov GN, Yeap BY, Jarrell E, Sun J, Tracy S, Zhao X, Heymach JV, Johnson BE, Cantley LC, Jänne PA.Allelic dilution obscures detection of a biologically significant resistance mutatio
  16906227
• Gordon GJ, Deters LA, Nitz MD, Lieberman BC, Yeap BY, Bueno R.Differential diagnosis of solitary lung nodules with gene expression ratios.J Thorac Cardiovasc Surg. 2006 Sep;132(3):621-7.
  16935118
• Jackman DM, Yeap BY, Sequist LV, Lindeman N, Holmes AJ, Joshi VA, Bell DW, Huberman MS, Halmos B, Rabin MS, Haber DA, Lynch TJ, Meyerson M, Johnson BE, Jänne PA.Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged s
  16818686
• Richards WG, Zellos L, Bueno R, Jaklitsch MT, Jänne PA, Chirieac LR, Yeap BY, Dekkers RJ, Hartigan PM, Capalbo L, Sugarbaker DJ.Phase I to II study of pleurectomy/decortication and intraoperative intracavitary hyperthermic cisplatin lavage for mesotheliom
  16575008
• Linden PA, Gilbert RJ, Yeap BY, Boyle K, Deykin A, Jaklitsch MT, Sugarbaker DJ, Bueno R.Laparoscopic fundoplication in patients with end-stage lung disease awaiting transplantation.J Thorac Cardiovasc Surg. 2006 Feb;131(2):438-46.
  16434276
• Mukohara T, Engelman JA, Hanna NH, Yeap BY, Kobayashi S, Lindeman N, Halmos B, Pearlberg J, Tsuchihashi Z, Cantley LC, Tenen DG, Johnson BE, Jänne PA.Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth f
  16106023
• Gordon GJ, Rockwell GN, Godfrey PA, Jensen RV, Glickman JN, Yeap BY, Richards WG, Sugarbaker DJ, Bueno R.Validation of genomics-based prognostic tests in malignant pleural mesothelioma.Clin Cancer Res. 2005 Jun 15;11(12):4406-14.
  15958625
• Mamon HJ, Yeap BY, Jänne PA, Reblando J, Shrager S, Jaklitsch MT, Mentzer S, Lukanich JM, Sugarbaker DJ, Baldini EH, Berman S, Skarin A, Bueno R.High risk of brain metastases in surgically staged IIIA non-small-cell lung cancer patients treated with surge
  15735128
• Ballen KK, Becker PS, Yeap BY, Matthews B, Henry DH, Ford PA.Autologous stem-cell transplantation can be performed safely without the use of blood-product support.J Clin Oncol. 2004 Oct 15;22(20):4087-94.
  15353543
• Jänne PA, Gurubhagavatula S, Yeap BY, Lucca J, Ostler P, Skarin AT, Fidias P, Lynch TJ, Johnson BE.Outcomes of patients with advanced non-small cell lung cancer treated with gefitinib (ZD1839, "Iressa") on an expanded access study.Lung Cancer. 2
  15084387
• Daly A, McAfee S, Dey B, Colby C, Schulte L, Yeap B, Sackstein R, Tarbell NJ, Sachs D, Sykes M, Spitzer TR.Nonmyeloablative bone marrow transplantation: Infectious complications in 65 recipients of HLA-identical and mismatched transplants.Biol Blood Marro
  12813445
• Gallagher RE, Yeap BY, Bi W, Livak KJ, Beaubier N, Rao S, Bloomfield CD, Appelbaum FR, Tallman MS, Slack JL, Willman CL.Quantitative real-time RT-PCR analysis of PML-RAR alpha mRNA in acute promyelocytic leukemia: assessment of prognostic significance in
  12468436
• Colby C, Koziol S, McAfee SL, Yeap B, Spitzer TR.High-dose carboplatin and regimen-related toxicity following autologous bone marrow transplant.Bone Marrow Transplant. 2002 Mar;29(6):467-72.
  11960264
• Pierie JP, Choudry U, Muzikansky A, Yeap BY, Souba WW, Ott MJ.The effect of surgery and grade on outcome of gastrointestinal stromal tumors.Arch Surg. 2001 Apr;136(4):383-9.
  11296107
• Yeap BY, Davidian M.Robust two-stage estimation in hierarchical nonlinear models.Biometrics. 2001 Mar;57(1):266-72.
  11252609