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Cynthia C. Morton, PhD

Publications

  • Romeike BF, Shen Y, Nishimoto HK, Morton CC, Layman LC, Kim HG.Spectrum of genes involved in a unique case of Potocki Schaffer syndrome with a large chromosome 11 deletion.Clin Neuropathol.;33(3):238-44.
    24780589
  • Ordulu Z, Wong KE, Currall BB, Ivanov AR, Pereira S, Althari S, Gusella JF, Talkowski ME, Morton CC.Describing Sequencing Results of Structural Chromosome Rearrangements with a Suggested Next-Generation Cytogenetic Nomenclature.Am J Hum Genet. 2014 Apr 16.
    24746958
  • Currall BB, Chiang C, Talkowski ME, Morton CC.Mechanisms for Structural Variation in the Human Genome.Curr Genet Med Rep. 2013 Jun 1;1(2):81-90.
    23730541
  • Genovese G, Handsaker RE, Li H, Altemose N, Lindgren AM, Chambert K, Pasaniuc B, Price AL, Reich D, Morton CC, Pollak MR, Wilson JG, McCarroll SA.Using population admixture to help complete maps of the human genome.Nat Genet. 2013 Apr;45(4):406-14.
    23435088
  • Talkowski ME, Ordulu Z, Pillalamarri V, Benson CB, Blumenthal I, Connolly S, Hanscom C, Hussain N, Pereira S, Picker J, Rosenfeld JA, Shaffer LG, Wilkins-Haug LE, Gusella JF, Morton CC.Clinical diagnosis by whole-genome sequencing of a prenatal sample.N Engl J Med. 2012 Dec 6;367(23):2226-32.
    23215558
  • Eggert SL, Huyck KL, Somasundaram P, Kavalla R, Stewart EA, Lu AT, Painter JN, Montgomery GW, Medland SE, Nyholt DR, Treloar SA, Zondervan KT, Heath AC, Madden PA, Rose L, Buring JE, Ridker PM, Chasman DI, Martin NG, Cantor RM, Morton CC.Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata.Am J Hum Genet. 2012 Oct 5;91(4):621-8.
    23040493
  • Kim HG, Kim HT, Leach NT, Lan F, Ullmann R, Silahtaroglu A, Kurth I, Nowka A, Seong IS, Shen Y, Talkowski ME, Ruderfer D, Lee JH, Glotzbach C, Ha K, Kjaergaard S, Levin AV, Romeike BF, Kleefstra T, Bartsch O, Elsea SH, Jabs EW, MacDonald ME, Harris DJ, Quade BJ, Ropers HH, Shaffer LG, Kutsche K, Layman LC, Tommerup N, Kalscheuer VM, Shi Y, Morton CC, Kim CH, Gusella JF.Translocations disrupting PHF21A in the Potocki-Shaffer-syndrome region are associated with intellectual disability and craniofacial anomalies.Am J Hum Genet. 2012 Jul 13;91(1):56-72.
    22770980
  • Ordulu Z, Dal Cin P, Chong WW, Choy KW, Lee C, Muto MG, Quade BJ, Morton CC.Disseminated peritoneal leiomyomatosis after laparoscopic supracervical hysterectomy with characteristic molecular cytogenetic findings of uterine leiomyoma.Genes Chromosomes Cancer. 2010 Dec;49(12):1152-60.
    20842731
  • Ligon AH, Morton CC, Bieber FR, Fletcher JA, Giersch AB, Kantarci S, Leach N, Lee C, Sandstrom M, Weremowicz S, Xiao S, Dal Cin P.Reporting of diagnostic cytogenetic results.Curr Protoc Hum Genet. 2010 Oct;Appendix 1:1D.1-23.
    20891028
  • Brown KK, Reiss JA, Crow K, Ferguson HL, Kelly C, Fritzsch B, Morton CC.Deletion of an enhancer near DLX5 and DLX6 in a family with hearing loss, craniofacial defects, and an inv(7)(q21.3q35).Hum Genet. 2010 Jan;127(1):19-31.
    19707792
  • , Birney E, Hudson TJ, Green ED, Gunter C, Eddy S, Rogers J, Harris JR, Ehrlich SD, Apweiler R, Austin CP, Berglund L, Bobrow M, Bountra C, Brookes AJ, Cambon-Thomsen A, Carter NP, Chisholm RL, Contreras JL, Cooke RM, Crosby WL, Dewar K, Durbin R, Dyke SO, Ecker JR, El Emam K, Feuk L, Gabriel SB, Gallacher J, Gelbart WM, Granell A, Guarner F, Hubbard T, Jackson SA, Jennings JL, Joly Y, Jones SM, Kaye J, Kennedy KL, Knoppers BM, Kyrpides NC, Lowrance WW, Luo J, MacKay JJ, Martín-Rivera L, McCombie WR, McPherson JD, Miller L, Miller W, Moerman D, Mooser V, Morton CC, Ostell JM, Ouellette BF, Parkhill J, Raina PS, Rawlings C, Scherer SE, Scherer SW, Schofield PN, Sensen CW, Stodden VC, Sussman MR, Tanaka T, Thornton J, Tsunoda T, Valle D, Vuorio EI, Walker NM, Wallace S, Weinstock G, Whitman WB, Worley KC, Wu C, Wu J, Yu J.Prepublication data sharing.Nature. 2009 Sep 10;461(7261):168-70.
    19741685
  • Hodge JC, Park PJ, Dreyfuss JM, Assil-Kishawi I, Somasundaram P, Semere LG, Quade BJ, Lynch AM, Stewart EA, Morton CC.Identifying the molecular signature of the interstitial deletion 7q subgroup of uterine leiomyomata using a paired analysis.Genes Chromosomes Cancer. 2009 Oct;48(10):865-85.
    19603527
  • Brown KK,Alkuraya FS,Matos M,Robertson RL,Kimonis VE,Morton CC.NR2F1 deletion in a patient with a de novo paracentric inversion, inv(5)(q15q33.2), and syndromic deafness.Am J Med Genet A. 2009 May;149A(5):931-8.
    19353646
  • Hodge JC,T Cuenco K,Huyck KL,Somasundaram P,Panhuysen CI,Stewart EA,Morton CC.Uterine leiomyomata and decreased height: a common HMGA2 predisposition allele.Hum Genet. 2009 Apr;125(3):257-63.
    19132395
  • Robertson NG,Jones SM,Sivakumaran TA,Giersch AB,Jurado SA,Call LM,Miller CE,Maison SF,Liberman MC,Morton CC.A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction.Hum Mol Genet. 2008 Nov 1;17(21):3426-34.
    18697796
  • Poitras JL,Dal Cin P,Aster JC,Deangelo DJ,Morton CC.Novel SSBP2-JAK2 fusion gene resulting from a t(5;9)(q14.1;p24.1) in pre-B acute lymphocytic leukemia.Genes Chromosomes Cancer. 2008 Oct;47(10):884-9.
    18618714
  • Hodge JC, Quade BJ, Rubin MA, Stewart EA, Dal Cin P, Morton CC.Molecular and cytogenetic characterization of plexiform leiomyomata provide further evidence for genetic heterogeneity underlying uterine fibroids.Am J Pathol. 2008 May;172(5):1403-10.
    18403592
  • Lee C, Morton CC.Structural genomic variation and personalized medicine.N Engl J Med. 2008 Feb 14;358(7):740-1.
    18272898
  • Huyck KL, Panhuysen CI, Cuenco KT, Zhang J, Goldhammer H, Jones ES, Somasundaram P, Lynch AM, Harlow BL, Lee H, Stewart EA, Morton CC.The impact of race as a risk factor for symptom severity and age at diagnosis of uterine leiomyomata among affected sisters.Am J Obstet Gynecol. 2008 Feb;198(2):168.e1-9.
    18226615
  • Chanock SJ, Manolio T, Boehnke M, Boerwinkle E, Hunter DJ, Thomas G, Hirschhorn JN, Abecasis G, Altshuler D, Bailey-Wilson JE, Brooks LD, Cardon LR, Daly M, Donnelly P, Fraumeni JF Jr, Freimer NB, Gerhard DS, Gunter C, Guttmacher AE, Guyer MS, Harris EL, Hoh J, Hoover R, Kong CA, Merikangas KR, Morton CC, Palmer LJ, Phimister EG, Rice JP, Roberts J, Rotimi C, Tucker MA, Vogan KJ, Wacholder S, Wijsman EM, Winn DM, Collins FS.Replicating genotype-phenotype associations.Nature. 2007 Jun 7;447(7145):655-60.
    17554299
  • Lu W, Quintero-Rivera F, Fan Y, Alkuraya FS, Donovan DJ, Xi Q, Turbe-Doan A, Li QG, Campbell CG, Shanske AL, Sherr EH, Ahmad A, Peters R, Rilliet B, Parvex P, Bassuk AG, Harris DJ, Ferguson H, Kelly C, Walsh CA, Gronostajski RM, Devriendt K, Higgins A, Ligon AH, Quade BJ, Morton CC, Gusella JF, Maas RL.NFIA haploinsufficiency is associated with a CNS malformation syndrome and urinary tract defects.PLoS Genet. 2007 May 25;3(5):e80.
    17530927
  • Lu W, van Eerde AM, Fan X, Quintero-Rivera F, Kulkarni S, Ferguson H, Kim HG, Fan Y, Xi Q, Li QG, Sanlaville D, Andrews W, Sundaresan V, Bi W, Yan J, Giltay JC, Wijmenga C, de Jong TP, Feather SA, Woolf AS, Rao Y, Lupski JR, Eccles MR, Quade BJ, Gusella JF, Morton CC, Maas RL.Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux.Am J Hum Genet. 2007 Apr;80(4):616-32.
    17357069
  • Leach NT, Sun Y, Michaud S, Zheng Y, Ligon KL, Ligon AH, Sander T, Korf BR, Lu W, Harris DJ, Gusella JF, Maas RL, Quade BJ, Cole AJ, Kelz MB, Morton CC.Disruption of diacylglycerol kinase delta (DGKD) associated with seizures in humans and mice.Am J Hum Genet. 2007 Apr;80(4):792-9.
    17357084
  • Kim HG, Higgins AW, Herrick SR, Kishikawa S, Nicholson L, Kutsche K, Ligon AH, Harris DJ, Macdonald ME, Bruns GA, Morton CC, Quade BJ, Gusella JF.Candidate loci for Zimmermann-Laband syndrome at 3p14.3.Am J Med Genet A. 2007 Jan 15;143(2):107-11.
    17163523
  • Treon SP, Hunter ZR, Aggarwal A, Ewen EP, Masota S, Lee C, Santos DD, Hatjiharissi E, Xu L, Leleu X, Tournilhac O, Patterson CJ, Manning R, Branagan AR, Morton CC.Characterization of familial Waldenstrom's macroglobulinemia.Ann Oncol. 2006 Mar;17(3):488-94.
    16357024
  • Christacos NC, Quade BJ, Dal Cin P, Morton CC.Uterine leiomyomata with deletions of Ip represent a distinct cytogenetic subgroup associated with unusual histologic features.Genes Chromosomes Cancer. 2006 Mar;45(3):304-12.
    16320247
  • Moore SD, Offor O, Ferry JA, Amrein PC, Morton CC, Dal Cin P.ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21)(q25-26;q22).Leuk Res. 2006 Aug;30(8):1037-42.
    16303180
  • Dettori T, Frau DV, Garcia JL, Pierantoni G, Lee C, Hernandez JM, Fusco A, Morton CC, Vanni R.Comprehensive conventional and molecular cytogenetic characterization of B-CPAP, a human papillary thyroid carcinoma-derived cell line.Cancer Genet Cytogenet. 2004 Jun;151(2):171-7.
    15172756
  • Quade BJ, Wang TY, Sornberger K, Dal Cin P, Mutter GL, Morton CC.Molecular pathogenesis of uterine smooth muscle tumors from transcriptional profiling.Genes Chromosomes Cancer. 2004 Jun;40(2):97-108.
    15101043
  • Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmyer J, Zucker JP, Wang S, Morton CC, McMahon AP, Powers D, Melton DA.Derivation of embryonic stem-cell lines from human blastocysts.N Engl J Med. 2004 Mar 25;350(13):1353-6.
    14999088
  • Porter D, Weremowicz S, Chin K, Seth P, Keshaviah A, Lahti-Domenici J, Bae YK, Monitto CL, Merlos-Suarez A, Chan J, Hulette CM, Richardson A, Morton CC, Marks J, Duyao M, Hruban R, Gabrielson E, Gelman R, Polyak K.A neural survival factor is a candidate oncogene in breast cancer.Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10931-6.
    12953101
  • Gross KL, Neskey DM, Manchanda N, Weremowicz S, Kleinman MS, Nowak RA, Ligon AH, Rogalla P, Drechsler K, Bullerdiek J, Morton CC.HMGA2 expression in uterine leiomyomata and myometrium: quantitative analysis and tissue culture studies.Genes Chromosomes Cancer. 2003 Sep;38(1):68-79.
    12874787
  • Mason HR, Nowak RA, Morton CC, Castellot JJ.Heparin inhibits the motility and proliferation of human myometrial and leiomyoma smooth muscle cells.Am J Pathol. 2003 Jun;162(6):1895-904.
    12759246
  • Scherer SW, Cheung J, MacDonald JR, Osborne LR, Nakabayashi K, Herbrick JA, Carson AR, Parker-Katiraee L, Skaug J, Khaja R, Zhang J, Hudek AK, Li M, Haddad M, Duggan GE, Fernandez BA, Kanematsu E, Gentles S, Christopoulos CC, Choufani S, Kwasnicka D, Zheng XH, Lai Z, Nusskern D, Zhang Q, Gu Z, Lu F, Zeesman S, Nowaczyk MJ, Teshima I, Chitayat D, Shuman C, Weksberg R, Zackai EH, Grebe TA, Cox SR, Kirkpatrick SJ, Rahman N, Friedman JM, Heng HH, Pelicci PG, Lo-Coco F, Belloni E, Shaffer LG, Pober B, Morton CC, Gusella JF, Bruns GA, Korf BR, Quade BJ, Ligon AH, Ferguson H, Higgins AW, Leach NT, Herrick SR, Lemyre E, Farra CG, Kim HG, Summers AM, Gripp KW, Roberts W, Szatmari P, Winsor EJ, Grzeschik KH, Teebi A, Minassian BA, Kere J, Armengol L, Pujana MA, Estivill X, Wilson MD, Koop BF, Tosi S, Moore GE, Boright AP, Zlotorynski E, Kerem B, Kroisel PM, Petek E, Oscier DG, Mould SJ, Dohner H, Dohner K, Rommens JM, Vincent JB, Venter JC, Li PW, Mural RJ, Adams MD, Tsui LC.Human chromosome 7: DNA sequence and biology.Science. 2003 May 2;300(5620):767-72.
    12690205
  • Quade BJ, Weremowicz S, Neskey DM, Vanni R, Ladd C, Dal Cin P, Morton CC.Fusion transcripts involving HMGA2 are not a common molecular mechanism in uterine leiomyomata with rearrangements in 12q15.Cancer Res. 2003 Mar 15;63(6):1351-8.
    12649198
  • Dal Cin P, Quade BJ, Neskey DM, Kleinman MS, Weremowicz S, Morton CC.Intravenous leiomyomatosis is characterized by a der(14)t(12;14)(q15;q24).Genes Chromosomes Cancer. 2003 Feb;36(2):205-6.
    12508249
  • Dal Cin P, Morton CC.1q42 approximately q44 is rarely cytogenetically involved in sporadic uterine leiomyomata.Cancer Genet Cytogenet. 2002 Oct 1;138(1):92-3.
    12419594
  • Ligon AH, Scott IC, Takahara K, Greenspan DS, Morton CC.PCOLCE deletion and expression analyses in uterine leiomyomata.Cancer Genet Cytogenet. 2002 Sep;137(2):133-7.
    12393284
  • Zhu C, Mills KD, Ferguson DO, Lee C, Manis J, Fleming J, Gao Y, Morton CC, Alt FW.Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.Cell. 2002;109:811-821.
  • Quade BJ, Dal Cin P, Neskey DM, Weremowicz S, Morton CC.Intravenous leiomyomatosis: molecular and cytogenetic analysis of a case.Mod Pathol. 2002 Mar;15(3):351-6.
    11904348
  • Enerbäck C, Porter DA, Seth P, Sgroi D, Gaudet J, Weremowicz S, Morton CC, Schnitt S, Pitts RL, Stampl J, Barnhart K, Polyak K.Psoriasin expression in mammary epithelial cells in vitro and in vivo.Cancer Res. 2002 Jan 1;62(1):43-7.
    11782356
  • Sharpless NE, Ferguson DO, O'Hagan RC, Castrillon DH, Lee C, Farazi PA, Alson S, Fleming J, Morton CC, Frank K, Chin L, Alt FW, DePinho RA.Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.Mol Cell. 2001 Dec;8(6):1187-96.
    11779495
  • Nucci MR, Weremowicz S, Neskey DM, Sornberger K, Tallini G, Morton CC, Quade BJ.Chromosomal translocation t(8;12) induces aberrant HMGIC expression in aggressive angiomyxoma of the vulva.Genes Chromosomes Cancer. 2001 Oct;32(2):172-6.
    11550285
  • Gross KL, Morton CC.Genetics and the development of fibroids.Clin Obstet Gynecol. 2001 Jun;44(2):335-49.
    11344997
  • Cheung VG, Nowak N, Jang W, Kirsch IR, Zhao S, Chen XN, Furey TS, Kim UJ, Kuo WL, Olivier M, Conroy J, Kasprzyk A, Massa H, Yonescu R, Sait S, Thoreen C, Snijders A, Lemyre E, Bailey JA, Bruzel A, Burrill WD, Clegg SM, Collins S, Dhami P, Friedman C, Han CS, Herrick S, Lee J, Ligon AH, Lowry S, Morley M, Narasimhan S, Osoegawa K, Peng Z, Plajzer-Frick I, Quade BJ, Scott D, Sirotkin K, Thorpe AA, Gray JW, Hudson J, Pinkel D, Ried T, Rowen L, Shen-Ong GL, Strausberg RL, Birney E, Callen DF, Cheng JF, Cox DR, Doggett NA, Carter NP, Eichler EE, Haussler D, Korenberg JR, Morton CC, Albertson D, Schuler G, de Jong PJ, Trask BJ.Integration of cytogenetic landmarks into the draft sequence of the human genome.Nature. 2001 Feb 15;409(6822):953-8.
    11237021
  • Dal Cin P, Atkins L, Ford C, Ariyanayagam S, Armstrong SA, George R, Cleary A, Morton CC.Amplification of AML1 in childhood acute lymphoblastic leukemias.Genes Chromosomes Cancer. 2001 Apr;30(4):407-9.
    11241794
  • Lee C, Gisselsson D, Jin C, Nordgren A, Ferguson DO, Blennow E, Fletcher JA, Morton CC.Limitations of chromosome classification by multicolor karyotyping.Am J Hum Genet. 2001 Apr;68(4):1043-7.
    11222105
  • Ligon AH, Morton CC.Leiomyomata: heritability and cytogenetic studies.Hum Reprod Update. 2001 Jan-Feb;7(1):8-14.
    11212080
  • Morton CC.Genetic approaches to the study of uterine leiomyomata.Environ Health Perspect. 2000 Oct;108 Suppl 5:775-8.
    11035981
  • Ligon AH, Morton CC.Genetics of uterine leiomyomata.Genes Chromosomes Cancer. 2000 Jul;28(3):235-45.
    10862029
  • Vaughan CJ, Weremowicz S, Goldstein MM, Casey M, Hart M, Hahn RT, Devereux RB, Girardi L, Schoen FJ, Fletcher JA, Morton CC, Basson CT.A t(2;19)(p13;p13.2) in a giant invasive cardiac lipoma from a patient with multiple lipomatosis.Genes Chromosomes Cancer. 2000 Jun;28(2):133-7.
    10824997
  • Pedeutour F, Quade BJ, Sornberger K, Tallini G, Ligon AH, Weremowicz S, Morton CC.Dysregulation of HMGIC in a uterine lipoleiomyoma with a complex rearrangement including chromosomes 7, 12, and 14.Genes Chromosomes Cancer. 2000 Feb;27(2):209-15.
    10612811
  • Faisal Ahmed S, Marsh DJ, Weremowicz S, Morton CC, Williams DM, Eng C.Balanced translocation of 10q and13q, including the PTEN gene, in a boy with a human chorionic gonadotropin-secreting tumor and the Bannayan-Riley-Ruvalcaba syndrome.J Clin Endocrinol Metab. 1999 Dec;84(12):4665-70.
    10599735
  • Pedeutour F, Ligon AH, Morton CC.[Genetics of uterine leiomyomata].Bull Cancer. 1999 Nov;86(11):920-8.
    10586108
  • Dal Cin P, Quade BJ, Weremowicz S, Morton CC, Pauwels P, Van Den Berghe H.Primary parauterine leiomyoma with a t(6;14).Genes Chromosomes Cancer. 1999 Dec;26(4):385-6.
    10534776
  • Sornberger KS, Weremowicz S, Williams AJ, Quade BJ, Ligon AH, Pedeutour F, Vanni R, Morton CC.Expression of HMGIY in three uterine leiomyomata with complex rearrangements of chromosome 6.Cancer Genet Cytogenet. 1999 Oct 1;114(1):9-16.
    10526529
  • Gattas GJ, Quade BJ, Nowak RA, Morton CC.HMGIC expression in human adult and fetal tissues and in uterine leiomyomata.Genes Chromosomes Cancer. 1999 Aug;25(4):316-22.
    10398424
  • Weremowicz S, Morton CC.Is HMGIC rearranged due to cryptic paracentric inversion of 12q in karyotypically normal uterine leiomyomas?.Genes Chromosomes Cancer. 1999 Feb;24(2):172-3.
    9885987
  • Pedeutour F, Quade BJ, Weremowicz S, Dal Cin P, Ali S, Morton CC.Localization and expression of the human estrogen receptor beta gene in uterine leiomyomata.Genes Chromosomes Cancer. 1998 Dec;23(4):361-6.
    9824210
  • Morton CC.Warner-Lambert/Parke-Davis Award lecture. Many tumors and many genes: genetics of uterine leiomyomata.Am J Pathol. 1998 Oct;153(4):1015-20.
    9777932
  • Quintana DG, Thome KC, Hou ZH, Ligon AH, Morton CC, Dutta A.ORC5L, a new member of the human origin recognition complex, is deleted in uterine leiomyomas and malignant myeloid diseases.J Biol Chem. 1998 Oct 16;273(42):27137-45.
    9765232
  • Rein MS, Powell WL, Walters FC, Weremowicz S, Cantor RM, Barbieri RL, Morton CC.Cytogenetic abnormalities in uterine myomas are associated with myoma size.Mol Hum Reprod. 1998 Jan;4(1):83-6.
    9510016
  • Xing YP, Powell WL, Morton CC.The del(7q) subgroup in uterine leiomyomata: genetic and biologic characteristics. Further evidence for the secondary nature of cytogenetic abnormalities in the pathobiology of uterine leiomyomata.Cancer Genet Cytogenet. 1997 Oct 1;98(1):69-74.
    9309121
  • Quade BJ, McLachlin CM, Soto-Wright V, Zuckerman J, Mutter GL, Morton CC.Disseminated peritoneal leiomyomatosis. Clonality analysis by X chromosome inactivation and cytogenetics of a clinically benign smooth muscle proliferation.Am J Pathol. 1997 Jun;150(6):2153-66.
    9176406
  • Williams AJ, Powell WL, Collins T, Morton CC.HMGI(Y) expression in human uterine leiomyomata. Involvement of another high-mobility group architectural factor in a benign neoplasm.Am J Pathol. 1997 Mar;150(3):911-8.
    9060829
  • Elson A, Wang Y, Daugherty CJ, Morton CC, Zhou F, Campos-Torres J, Leder P.Pleiotropic defects in ataxia-telangiectasia protein-deficient mice.Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13084-9.
    8917548
  • Schoenberg Fejzo M, Ashar HR, Krauter KS, Powell WL, Rein MS, Weremowicz S, Yoon SJ, Kucherlapati RS, Chada K, Morton CC.Translocation breakpoints upstream of the HMGIC gene in uterine leiomyomata suggest dysregulation of this gene by a mechanism different from that in lipomas.Genes Chromosomes Cancer. 1996 Sep;17(1):1-6.
    8889500
  • Ashar HR, Fejzo MS, Tkachenko A, Zhou X, Fletcher JA, Weremowicz S, Morton CC, Chada K.Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains.Cell. 1995 Jul 14;82(1):57-65.
    7606786
  • Gorn AH, Rudolph SM, Flannery MR, Morton CC, Weremowicz S, Wang TZ, Krane SM, Goldring SR.Expression of two human skeletal calcitonin receptor isoforms cloned from a giant cell tumor of bone. The first intracellular domain modulates ligand binding and signal transduction.J Clin Invest. 1995 Jun;95(6):2680-91.
    7769107
  • Sargent MS, Weremowicz S, Rein MS, Morton CC.Translocations in 7q22 define a critical region in uterine leiomyomata.Cancer Genet Cytogenet. 1994 Oct;77(1):65-8.
    7923086
  • Weremowicz S, Kozakewich HP, Haber D, Park S, Morton CC, Fletcher JA.Identification of genetically aberrant cell lineages in Wilms' tumors.Genes Chromosomes Cancer. 1994 May;10(1):40-8.
    7519872
  • Fletcher JA, Kozakewich HP, Schoenberg ML, Morton CC.Cytogenetic findings in pediatric adipose tumors: consistent rearrangement of chromosome 8 in lipoblastoma.Genes Chromosomes Cancer. 1993 Jan;6(1):24-9.
    7680218
  • Reynolds JE, Fletcher JA, Lytle CH, Nie L, Morton CC, Diehl SR.Molecular characterization of a 17q11.2 translocation in a malignant schwannoma cell line.Hum Genet. 1992 Dec;90(4):450-6.
    1483704
  • Fletcher JA, Pinkus JL, Lage JM, Morton CC, Pinkus GS.Clonal 6p21 rearrangement is restricted to the mesenchymal component of an endometrial polyp.Genes Chromosomes Cancer. 1992 Oct;5(3):260-3.
    1384681
  • Weremowicz S, Kupsky WJ, Morton CC, Fletcher JA.Cytogenetic evidence for a chromosome 22 tumor suppressor gene in ependymoma.Cancer Genet Cytogenet. 1992 Jul 15;61(2):193-6.
    1638502
  • Davis TH, Morton CC, Miller-Cassman R, Balk SP, Kadin ME.Hodgkin's disease, lymphomatoid papulosis, and cutaneous T-cell lymphoma derived from a common T-cell clone.N Engl J Med. 1992 Apr 23;326(17):1115-22.
    1532439
  • Fletcher JA, Henkle C, Atkins L, Rosenberg AE, Morton CC.Trisomy 5 and trisomy 7 are nonrandom aberrations in pigmented villonodular synovitis: confirmation of trisomy 7 in uncultured cells.Genes Chromosomes Cancer. 1992 Apr;4(3):264-6.
    1382569
  • Robertson NG, Pomponio RJ, Mutter GL, Morton CC.Testis-specific expression of the human MYCL2 gene.Nucleic Acids Res. 1991 Jun 11;19(11):3129-37.
    1711681
  • Rein MS, Friedman AJ, Barbieri RL, Pavelka K, Fletcher JA, Morton CC.Cytogenetic abnormalities in uterine leiomyomata.Obstet Gynecol. 1991 Jun;77(6):923-6.
    2030869
  • Fletcher JA, Pinkus GS, Weidner N, Morton CC.Lineage-restricted clonality in biphasic solid tumors.Am J Pathol. 1991 May;138(5):1199-207.
    1708947
  • Fletcher JA, Gibas Z, Donovan K, Perez-Atayde A, Genest D, Morton CC, Lage JM.Ovarian granulosa-stromal cell tumors are characterized by trisomy 12.Am J Pathol. 1991 Mar;138(3):515-20.
    2000932
  • Fletcher JA, Kozakewich HP, Hoffer FA, Lage JM, Weidner N, Tepper R, Pinkus GS, Morton CC, Corson JM.Diagnostic relevance of clonal cytogenetic aberrations in malignant soft-tissue tumors.N Engl J Med. 1991 Feb 14;324(7):436-42.
    1988828
  • Fletcher JA, Kozakewich HP, Pavelka K, Grier HE, Shamberger RC, Korf B, Morton CC.Consistent cytogenetic aberrations in hepatoblastoma: a common pathway of genetic alterations in embryonal liver and skeletal muscle malignancies?.Genes Chromosomes Cancer. 1991 Jan;3(1):37-43.
    1648956
  • Ray RA, Morton CC, Lipinski KK, Corson JM, Fletcher JA.Cytogenetic evidence of clonality in a case of pigmented villonodular synovitis.Cancer. 1991 Jan 1;67(1):121-5.
    1985707
  • Fletcher JA, Morton CC, Pavelka K, Lage JM.Chromosome aberrations in uterine smooth muscle tumors: potential diagnostic relevance of cytogenetic instability.Cancer Res. 1990 Jul 1;50(13):4092-7.
    2354458
  • Zutter M, Hockett RD, Roberts CW, McGuire EA, Bloomstone J, Morton CC, Deaven LL, Crist WM, Carroll AJ, Korsmeyer SJ.The t(10;14)(q24;q11) of T-cell acute lymphoblastic leukemia juxtaposes the delta T-cell receptor with TCL3, a conserved and activated locus at 10q24.Proc Natl Acad Sci U S A. 1990 Apr;87(8):3161-5.
    2326274
  • Band V, Zajchowski D, Stenman G, Morton CC, Kulesa V, Connolly J, Sager R.A newly established metastatic breast tumor cell line with integrated amplified copies of ERBB2 and double minute chromosomes.Genes Chromosomes Cancer. 1989 Sep;1(1):48-58.
    2487147
  • Fletcher JA, Lipinski KK, Weidner N, Morton CC.Complex cytogenetic aberrations in a well-differentiated chondrosarcoma.Cancer Genet Cytogenet. 1989 Aug;41(1):115-21.
    2766246
  • Fletcher JA, Aster JC, Morton CC.Association of trisomy 8 and squamous differentiation in an endometrial adenocarcinoma.Cancer Genet Cytogenet. 1989 Jun;39(2):185-9.
    2752371
  • Morton CC, Nussenzweig MC, Sousa R, Sorenson GD, Pettengill OS, Shows TB.Mapping and characterization of an X-linked processed gene related to MYCL1.Genomics. 1989 Apr;4(3):367-75.
    2541066
  • Spies T, Morton CC, Nedospasov SA, Fiers W, Pious D, Strominger JL.Genes for the tumor necrosis factors alpha and beta are linked to the human major histocompatibility complex.Proc Natl Acad Sci U S A. 1986 Nov;83(22):8699-702.
    3464978
  • Harris P, Morton CC, Guglielmi P, Li F, Kelly K, Latt SA.Mapping by chromosome sorting of several gene probes, including c-myc, to the derivative chromosomes of a 3;8 translocation associated with familial renal cancer.Cytometry. 1986 Nov;7(6):589-94.
    3536362
  • Kirsch IR, Brown JA, Lawrence J, Korsmeyer SJ, Morton CC.Translocations that highlight chromosomal regions of differentiated activity.Cancer Genet Cytogenet. 1985 Oct;18(2):159-71.
    3863696
  • Morton CC, Duby AD, Eddy RL, Shows TB, Seidman JG.Genes for beta chain of human T-cell antigen receptor map to regions of chromosomal rearrangement in T cells.Science. 1985 May 3;228(4699):582-5.
    3983642
  • Morton CC, Taub R, Diamond A, Lane MA, Cooper GM, Leder P.Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1.Science. 1984 Jan 13;223(4632):173-5.
    6691143
  • Bonner T, O'Brien SJ, Nash WG, Rapp UR, Morton CC, Leder P.The human homologs of the raf (mil) oncogene are located on human chromosomes 3 and 4.Science. 1984 Jan 6;223(4631):71-4.
    6691137
  • Taub R, Kirsch I, Morton C, Lenoir G, Swan D, Tronick S, Aaronson S, Leder P.Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.Proc Natl Acad Sci U S A. 1982 Dec;79(24):7837-41.
    6818551