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Xihong Lin, PhD


  • Dicker L, Lin X.Parallelism, uniqueness, and large-sample asymptotics for the Dantzig selector.The Canadian Journal Of Statistics. 2013 Mar 1;41(1):23-35.
  • Ter-Minassian M, Chan JA, Hooshmand SM, Brais LK, Daskalova A, Heafield R, Buchanan L, Qian ZR, Fuchs CS, Lin X, Christiani DC, Kulke MH.Clinical presentation, recurrence, and survival in patients with neuroendocrine tumors: results from a prospective institutional database.Endocr. Relat. Cancer. 2013;20(2):187-96.
  • Barnett IJ, Lee S, Lin X.Detecting rare variant effects using extreme phenotype sampling in sequencing association studies.Genet Epidemiol. 2013 Feb;37(2):142-51.
  • Zhao Y, Chen F, Zhai R, Lin X, Diao N, Christiani DC.Association Test Based on SNP Set: Logistic Kernel Machine Based Test vs. Principal Component Analysis.PLoS ONE. 2012;7(9):e44978.
  • Cai T, Lin X, Carroll RJ.Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test.Biostatistics. 2012 Sep;13(4):776-90.
  • Lee S, Wu MC, Lin X.Optimal tests for rare variant effects in sequencing association studies.Biostatistics. 2012 Sep;13(4):762-75.
  • Wang L, Rotnitzky A, Lin X, Millikan RE, Thall PF.Evaluation of Viable Dynamic Treatment Regimes in a Sequentially Randomized Trial of Advanced Prostate Cancer.Journal of the American Statistical Association. 2012 Jun;107(498):493-508.
  • Lee S, Emond MJ, Bamshad MJ, Barnes KC, Rieder MJ, Nickerson DA, , Christiani DC, Wurfel MM, Lin X.Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies.Am J Hum Genet. 2012 Aug 10;91(2):224-37.
  • Cai T, Tonini G, Lin X.Kernel Machine Approach to Testing the Significance of Multiple Genetic Markers for Risk Prediction.Biometrics. 2011 Jan 31.
  • Dicker L, Lin X, Ivanov AR.Increased power for the analysis of label-free LC-MS/MS proteomic data by combining spectral counts and peptide peak attributes.Mol Cell Proteomics. 2010 Dec;9(12):2704-18.
  • Wang L, Rotnitzky A, Lin X.Nonparametric Regression With Missing Outcomes Using Weighted Kernel Estimating Equations.JASA.;105(491):1135-1146.
  • Paulus JK, Zhou W, Kraft P, Johnson BE, Lin X, Christiani DC.Haplotypes of estrogen receptor-beta and risk of non-small cell lung cancer in women.Lung Cancer. 2010 Jul 22.
  • Liu CY, Wu MC, Chen F, Ter-Minassian M, Asomaning K, Zhai R, Wang Z, Su L, Heist RS, Kulke MH, Lin X, Liu G, Christiani DC.A Large Scale Genetic Association Study of Esophageal Adenocarcinoma Risk.Carcinogenesis. 2010 Jul;31(7):1259-63.
  • Wu MC, Kraft P, Epstein MP, Taylor DM, Chanock SJ, Hunter DJ, Lin X.Powerful SNP-set analysis for case-control genome-wide association studies.Am J Hum Genet. 2010 Jun 11;86(6):929-42.
  • Li Y,Lin X,Muller P.Bayesian Inference in Semiparametric Mixed Models for Longitudinal Data.Biometrics. 2010 Mar;66(1):70-8.
  • Naylor MG, Lin X, Weiss ST, Raby BA, Lange C.Using canonical correlation analysis to discover genetic regulatory variants.PLoS ONE. 2010;5(5):e10395.
  • Epstein MP, Hunter JE, Allen EG, Sherman SL, Lin X, Boehnke M.A Variance-Component Framework for Pedigree Analysis of Continuous and Categorical Outcomes.Statistics In Biosciences. 2009 Nov;1(2):181-198.
  • Zhai R, Chen F, Liu G, Su L, Kulke MH, Asomaning K, Lin X, Heist RS, Nishioka NS, Sheu CC, Wain JC, Christiani DC.Interactions among genetic variants in apoptosis pathway genes, reflux symptoms, body mass index, and smoking indicate two distinct etiologic patterns of esophageal adenocarcinoma.J Clin Oncol. 2010 May 10;28(14):2445-51.
  • Paulus JK, Asomaning K, Kraft P, Johnson BE, Lin X, Christiani DC.Parity and risk of lung cancer in women.Am J Epidemiol. 2010 Mar 1;171(5):557-63.
  • Wu MC, Lin X.Prior biological knowledge-based approaches for the analysis of genome-wide expression profiles using gene sets and pathways.Statistical Methods in Medical Research. 2009 Dec;18(6):577-93.
  • Wu M, Lin X.Prior biological knowledge based approaches for the analysis of genome-wide expression profiles using gene sets and pathways.Statistical Methods in Medical Research..
  • Pan W,Zeng D,Lin X.Estimation in Semiparametric Transition Measurement Error Models for Longitudinal Data.Biometrics. 2009 Sep;65(3):728-36.
  • Little RJ,Long Q,Lin X.A Comparison of Methods for Estimating the Causal Effect of a Treatment in Randomized Clinical Trials Subject to Noncompliance.Biometrics. 2009 Jun;65(2):640-9.
  • Huang YT,Heist RS,Chirieac LR,Lin X,Skaug V,Zienolddiny S,Haugen A,Wu MC,Wang Z,Su L,Asomaning K,Christiani DC.Genome-wide analysis of survival in early-stage non-small-cell lung cancer.J Clin Oncol. 2009 Jun 1;27(16):2660-7.
  • Wu MC,Zhang L,Wang Z,Christiani DC,Lin X.Sparse linear discriminant analysis for simultaneous testing for the significance of a gene set/pathway and gene selection.Bioinformatics. 2009 May 1;25(9):1145-51.
  • Li Y,Prentice RL,Lin X.Semiparametric Maximum Likelihood Estimation in Normal Transformation Models for Bivariate Survival Data.Biometrika. 2008 Dec;95(4):947-960.
  • Ye W, Lin X, Taylor JM.Semiparametric Modeling of Longitudinal Measurements and Time-to-Event Data-A Two-Stage Regression Calibration Approach.Biometrics. 2008 Dec;64(4):1238-46.
  • Zhai R,Liu G,Asomaning K,Su L,Kulke MH,Heist RS,Nishioka NS,Lynch TJ,Wain JC,Lin X,Christiani DC.Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk.Carcinogenesis. 2008 Dec;29(12):2330-4.
  • Ter-Minassian M,Zhai R,Asomaning K,Su L,Zhou W,Liu G,Heist RS,Lynch TJ,Wain JC,Lin X,De Vivo I,Christiani DC.Apoptosis gene polymorphisms, age, smoking and the risk of non-small cell lung cancer.Carcinogenesis. 2008 Nov;29(11):2147-52.
  • Liu D,Ghosh D,Lin X.Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via logistic mixed models.BMC Bioinformatics. 2008;9:292.
  • Long Q, Little RJ, Lin X.Causal Inference in Hybrid Intervention Trials Involving Treatment Choice.JASA.;103(482):474-484.
  • Sanda MG, Dunn RL, Michalski J, Sandler HM, Northouse L, Hembroff L, Lin X, Greenfield TK, Litwin MS, Saigal CS, Mahadevan A, Klein E, Kibel A, Pisters LL, Kuban D, Kaplan I, Wood D, Ciezki J, Shah N, Wei JT.Quality of life and satisfaction with outcome among prostate-cancer survivors.N Engl J Med. 2008 Mar 20;358(12):1250-61.
  • Nan B, Lin X.Analysis of case-control age-at-onset data using a modified case-cohort method.Biom J. 2008 Apr;50(2):311-20.
  • Heist RS, Zhai R, Liu G, Zhou W, Lin X, Su L, Asomaning K, Lynch TJ, Wain JC, Christiani DC.VEGF polymorphisms and survival in early-stage non-small-cell lung cancer.J Clin Oncol. 2008 Feb 20;26(6):856-62.
  • Kwee LC,Liu D,Lin X,Ghosh D,Epstein MP.A powerful and flexible multilocus association test for quantitative traits.Am J Hum Genet. 2008 Feb;82(2):386-97.
  • Zhai R, Liu G, Zhou W, Su L, Heist RS, Lynch TJ, Wain JC, Asomaning K, Lin X, Christiani DC.Vascular endothelial growth factor genotypes, haplotypes, gender, and the risk of non-small cell lung cancer.Clin Cancer Res. 2008 Jan 15;14(2):612-7.
  • Yu Z, Lin X.Nonparametric regression using local kernel estimating equations for correlated failure time data.Biometrika.;95(1):123-137.
  • Ye W, Lin X.A penalized likelihood approach to joint modeling of longitudinal measurements and time to event data.Statistics and its Interface.(1):33-45.
  • Harezlak J,Wu MC,Wang M,Schwartzman A,Christiani DC,Lin X.Biomarker discovery for arsenic exposure using functional data. Analysis and feature learning of mass spectrometry proteomic data.J Proteome Res. 2008 Jan;7(1):217-24.
  • Lin X.Estimation using penalized quasilikelihood and quasi-pseudo-likelihood in Poisson mixed models.Lifetime Data Analysis. 2007 Dec;13(4):533-44.
  • Liu D, Lin X, Ghosh D.Semiparametric regression of multidimensional genetic pathway data: least-squares kernel machines and linear mixed models.Biometrics. 2007 Dec;63(4):1079-88.
  • Schipper M, Taylor JM, Lin X.Bayesian generalized monotonic functional mixed models for the effects of radiation dose histograms on normal tissue complications.Stat Med. 2007 Nov 10;26(25):4643-56.
  • Ji H, Ramsey MR, Hayes DN, Fan C, McNamara K, Kozlowski P, Torrice C, Wu MC, Shimamura T, Perera SA, Liang MC, Cai D, Naumov GN, Bao L, Contreras CM, Li D, Chen L, Krishnamurthy J, Koivunen J, Chirieac LR, Padera RF, Bronson RT, Lindeman NI, Christiani DC, Lin X, Shapiro GI, Janne PA, Johnson BE, Meyerson M, Kwiatkowski DJ, Castrillon DH, Bardeesy N, Sharpless NE, Wong KK.LKB1 modulates lung cancer differentiation and metastasis.Nature. 2007 Aug 16;448(7155):807-10.
  • Harezlak J,Wang M,Christiani D,Lin X.Quantitative quality-assessment techniques to compare fractionation and depletion methods in SELDI-TOF mass spectrometry experiments.Bioinformatics. 2007 Sep 15;23(18):2441-8.
  • Grewal J, Sowers MR, Randolph JF, Harlow SD, Lin X.Low bone mineral density in the early menopausal transition: role for ovulatory function.J Clin Endocrinol Metab. 2006 Oct;91(10):3780-5.
  • Diez Roux AV, Auchincloss AH, Astor B, Barr RG, Cushman M, Dvonch T, Jacobs DR, Kaufman J, Lin X, Samson P.Recent exposure to particulate matter and C-reactive protein concentration in the multi-ethnic study of atherosclerosis.Am J Epidemiol. 2006 Sep 1;164(5):437-48.
  • Cabana MD, Slish KK, Evans D, Mellins RB, Brown RW, Lin X, Kaciroti N, Clark NM.Impact of physician asthma care education on patient outcomes.Pediatrics. 2006 Jun;117(6):2149-57.
  • Li Y, Lin X.Semiparametric normal transformation models for spatially correlated survival data.Journal of the American Statistical Association. 2006 Jun;101(474):591-603.