Daniel B. Costa, MD, PhD

Publications

• Costa DB, Kobayashi S, Pandya SS, Yeo WL, Shen Z, Tan W, Wilner KD.CSF Concentration of the Anaplastic Lymphoma Kinase Inhibitor Crizotinib.J Clin Oncol. 2011 Mar 21.
  21422405
• Ortiz TM, Cohen DW, Kent MS, Jänne PA, Costa DB.KRAS mutation analysis helps to differentiate between pulmonary metastasis from colon adenocarcinoma in situ and primary lung adenocarcinoma.J Thorac Oncol. 2011 Jan;6(1):220-2.
  21178719
• Heon S, Yeap BY, Britt GJ, Costa DB, Rabin MS, Jackman DM, Johnson BE.Development of central nervous system metastases in patients with advanced non-small cell lung cancer and somatic EGFR mutations treated with gefitinib or erlotinib.Clin Cancer Res. 201
  21030498
• Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, Maki RG, Ou SH, Dezube BJ, Jänne PA, Costa DB, Varella-Garcia M, Kim WH, Lynch TJ, Fidias P, Stubbs H, Engelman JA, Sequist LV, Tan W, Gandhi L, Mino-Kenudson M, Wei GC, Shreeve SM, Ratain MJ, Settleman J
  20979469
• Cheng H, Xu X, Costa DB, Powell CA, Halmos B.Molecular testing in lung cancer: the time is now.Curr Oncol Rep. 2010 Sep;12(5):335-48.
  20623207
• Costa DB, Kobayashi S, Yeo WL, Hamada A.Serum concentrations of Erlotinib at a dose of 25 mg daily.J Thorac Oncol. 2010 Aug;5(8):1311-2.
  20661096
• Yeo WL, Riely GJ, Yeap BY, Lau MW, Warner JL, Bodio K, Huberman MS, Kris MG, Tenen DG, Pao W, Kobayashi S, Costa DB.Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with EGFR mutations.J Thorac Oncol. 2010 Jul;5(7):1048-53.
  20512075
• Will B, Siddiqi T, Alberich Jordà M, Shimamura T, Luptakova K, Staber PB, Costa DB, Steidl U, Tenen DG, Kobayashi S.Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells.Blood
  20160166
• Shaw AT, Yeap BY, Mino-Kenudson M, Digumarthy SR, Costa DB, Heist RS, Solomon B, Stubbs H, Admane S, McDermott U, Settleman J, Kobayashi S, Mark EJ, Rodig SJ, Chirieac LR, Kwak EL, Lynch TJ, Iafrate AJ.Clinical Features and Outcome of Patients With Non-Sm
  19667264
• Nguyen KS, Kobayashi S, Costa DB.Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway.Clin Lung Cancer. 2009 Jul;10(4):281-9. Review.
  19632948
• Costa DB,Kobayashi S.Gefitinib plus docetaxel in non-small-cell lung cancer.Lancet. 2009 Feb 14;373(9663):541; author reply 542.
  19217979
• Costa DB,Nguyen KS,Cho BC,Sequist LV,Jackman DM,Riely GJ,Yeap BY,Halmos B,Kim JH,Janne PA,Huberman MS,Pao W,Tenen DG,Kobayashi S.Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib.Clin Cancer Res. 2008 Nov 1;14(2
  18981003
• Honma HN, De Capitani EM, Perroud MW Jr, Barbeiro AS, Toro IF, Costa DB, Lima CS, Zambon L.Influence of p53 codon 72 exon 4, GSTM1, GSTT1 and GSTP1*B polymorphisms in lung cancer risk in a Brazilian population.Lung Cancer. 2008 Aug;61(2):152-62.
  18280004
• Costa DB, Schumer ST, Tenen DG, Kobayashi S.Differential responses to erlotinib in epidermal growth factor receptor (EGFR)-mutated lung cancers with acquired resistance to gefitinib carrying the L747S or T790M secondary mutations.J Clin Oncol. 2008 Mar 1;
  18309959
• Costa DB, Kobayashi S.Response of intracranial metastases to epidermal growth factor receptor tyrosine kinase inhibitors: it may all depend on EGFR mutations.J Clin Oncol. 2008 Feb 1;26(4):686.
  18235134
• Costa DB, Kobayashi S, Schumer ST.Erlotinib-associated alopecia in a lung cancer patient.J Thorac Oncol. 2007 Dec;2(12):1136-8.
  18090591
• Costa DB, Halmos B, Kumar A, Schumer ST, Huberman MS, Boggon TJ, Tenen DG, Kobayashi S.BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations.PLoS Med. 2007 Oct;4(10):1669-79; discussion 1680.
  17973572
• Steidl U, Steidl C, Ebralidze A, Chapuy B, Han HJ, Will B, Rosenbauer F, Becker A, Wagner K, Koschmieder S, Kobayashi S, Costa DB, Schulz T, O'Brien KB, Verhaak RG, Delwel R, Haase D, Trumper L, Krauter J, Kohwi-Shigematsu T, Griesinger F, Tenen DG.A
  17694175
• Costa DB, Kobayashi S, Tenen DG, Huberman MS.Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers.Lung Cancer. 2007 Oct;58(1):95-103.
  17610986
• Costa DB.To re-treat or not with gefitinib/erlotinib: This is the question for tyrosine kinase inhibitor-responsive lung cancers that progress.Lung Cancer. 2007 Aug;57(2):251-2.
  17566601
• Costa DB, Li S, Kocher O, Feins RH, Keller SM, Schiller JH, Johnson DH, Tenen DG, Halmos B.Immunohistochemical analysis of C/EBPalpha in non-small cell lung cancer reveals frequent down-regulation in stage II and IIIA tumors: A correlative study of E3590.
  17239984
• Costa DB, Kobayashi S.Are exon 19 deletions and L858R EGFR mutations in non-small-cell lung cancer clinically different?.Br J Cancer. 2007 Jan 29;96(2):399; author reply 400.
  17224926
• Steidl U, Rosenbauer F, Verhaak RG, Gu X, Ebralidze A, Otu HH, Klippel S, Steidl C, Bruns I, Costa DB, Wagner K, Aivado M, Kobbe G, Valk PJ, Passegué E, Libermann TA, Delwel R, Tenen DG.Essential role of Jun family transcription factors in PU.1 knockdown-
  17041602
• Costa DB, Miksad RA, Buff MS, Wang Y, Dezube BJ.Case of fatal sickle cell intrahepatic cholestasis despite use of exchange transfusion in an African-American patient.J Natl Med Assoc. 2006 Jul;98(7):1183-7.
  16895293
• Costa DB, Huberman MS.Improvement of type 2 diabetes in a lung cancer patient treated with Erlotinib.Diabetes Care. 2006 Jul;29(7):1711.
  16801611
• Costa DB, Dayaram T, D'Alo F, Wouters BJ, Tenen DG, Meyerson M, Tsao MS, Halmos B.C/EBPalpha mutations in lung cancer.Lung Cancer. 2006 Aug;53(2):253-4.
  16765476
• Costa DB, Schumer ST.Three-year survival in metastatic non-small cell lung cancer treated with gefitinib.Lung Cancer. 2006 Jul;53(1):123-4.
  16723171
• Costa DB.Recurrent infections in multiple myeloma.Mayo Clin Proc. 2006 Apr;81(4):567-8; author reply 568.
  16610581
• Costa DB, Stuart KE, Inzucchi SE.Hyperglycemia and biliary tract adenocarcinoma.J Gastroenterol Hepatol. 2006 Feb;21(2):484-5.
  16509886
• Costa DB, Fisher CA, Miller KB, Pihan GA, Steensma DP, Gibbons RJ, Higgs DR.A novel mutation in the last exon of ATRX in a patient with alpha-thalassemia myelodysplastic syndrome.Eur J Haematol. 2006 May;76(5):432-5, 453.
  16480427
• Costa DB, Parker JA, Schumer ST.Modern treatment of lung cancer: case 3. Non-metastatic bilateral F-18 fluorodeoxyglucose avid adrenal glands in non-small-cell lung cancer.J Clin Oncol. 2005 Oct 20;23(30):7740-2.
  16234534
• Costa DB, Lozovatsky L, Gallagher PG, Forget BG.A novel splicing mutation of the alpha-spectrin gene in the original hereditary pyropoikilocytosis kindred.Blood. 2005 Dec 15;106(13):4367-9.
  16150946
• Costa DB, Chen AA, Marginean EC, Inzucchi SE.Diabetes mellitus as the presenting feature of extrahepatic cholangiocarcinoma in situ: case report and review of literature.Endocr Pract. 2004 Sep-Oct;10(5):417-23.
  15760789
• Bonon SH, Menoni SM, Rossi CL, De Souza CA, Vigorito AC, Costa DB, Costa SC.Surveillance of cytomegalovirus infection in haematopoietic stem cell transplantation patients.J Infect. 2005 Feb;50(2):130-7.
  15667914
• Costa DB, Shin B, Cooper DL.Pneumococcemia as the presenting feature of multiple myeloma.Am J Hematol. 2004 Nov;77(3):277-81.
  15495248