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Sheila M. Thomas, PhD


  • Mack HI, Zheng B, Asara J, Thomas SM.AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization.Autophagy. 2012 Aug 1;8(8):1197-214.
  • Liu Y, Preston R, Thomas SM, Brackenridge A, Carroll PV.Cerebral cavernoma: an emerging long-term consequence of external beam radiation in childhood.Clin Endocrinol (Oxf). 2010 Nov;73(5):555-60. Review.
  • Wheeler SE, Suzuki S, Thomas SM, Sen M, Leeman-Neill RJ, Chiosea SI, Kuan CT, Bigner DD, Gooding WE, Lai SY, Grandis JR.Epidermal growth factor receptor variant III mediates head and neck cancer cell invasion via STAT3 activation.Oncogene. 2010 Sep 16;29(37):5135-45.
  • Taoudi Benchekroun M, Saintigny P, Thomas SM, El-Naggar AK, Papadimitrakopoulou V, Ren H, Lang W, Fan YH, Huang J, Feng L, Lee JJ, Kim ES, Hong WK, Johnson FM, Grandis JR, Mao L.Epidermal growth factor receptor expression and gene copy number in the risk of oral cancer.Cancer Prev Res (Phila Pa). 2010 Jul;3(7):800-9.
  • Armour SM, Baur JA, Hsieh SN, Land-Bracha A, Thomas SM, Sinclair DA.Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy.Aging (Albany NY). 2009 Jun;1(6):515-28.
  • Miranda MB, Duan R, Thomas SM, Grandis JR, Redner RL, Jones JE, Johnson DE.Gefitinib potentiates myeloid cell differentiation by ATRA.Leukemia. 2008 Aug;22(8):1624-7.
  • Thomas SM, Ogagan MJ, Freilino ML, Strychor S, Walsh DR, Gooding WE, Grandis JR, Zamboni WC.Antitumor mechanisms of systemically administered epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck.Mol Pharmacol. 2008 Mar;73(3):627-38.
  • King DA, Thomas SM.Big lessons for a healthy future.Nature. 2007 Oct 18;449(7164):791-2.
  • Liu S, Thomas SM, Woodside DG, Rose DM, Kiosses WB, Pfaff M, Ginsberg MH.Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses.Nature. 1999 Dec 9;402(6762):676-81.
  • Oh ES, Gu H, Saxton TM, Timms JF, Hausdorff S, Frevert EU, Kahn BB, Pawson T, Neel BG, Thomas SM.Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2.Mol Cell Biol. 1999 Apr;19(4):3205-15.
  • Thomas SM, Hagel M, Turner CE.Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin.J Cell Sci. 1999 Jan;112 ( Pt 2):181-90.
  • Thomas SM, Brugge JS.Cellular functions regulated by Src family kinases.Annu Rev Cell Dev Biol. 1997;13:513-609.
  • Ishida M, Ishida T, Thomas SM, Berk BC.Activation of extracellular signal-regulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells.Circ Res. 1998 Jan 9-23;82(1):7-12.
  • Rusanescu G, Qi H, Thomas SM, Brugge JS, Halegoua S.Calcium influx induces neurite growth through a Src-Ras signaling cassette.Neuron. 1995 Dec;15(6):1415-25.
  • Weng Z, Thomas SM, Rickles RJ, Taylor JA, Brauer AW, Seidel-Dugan C, Michael WM, Dreyfuss G, Brugge JS.Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains.Mol Cell Biol. 1994 Jul;14(7):4509-21.
  • Seidel-Dugan C, Meyer BE, Thomas SM, Brugge JS.Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src.Mol Cell Biol. 1992 Apr;12(4):1835-45.
  • Thomas SM, DeMarco M, D'Arcangelo G, Halegoua S, Brugge JS.Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases.Cell. 1992 Mar 20;68(6):1031-40.
  • Kremer NE, D'Arcangelo G, Thomas SM, DeMarco M, Brugge JS, Halegoua S.Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions.J Cell Biol. 1991 Nov;115(3):809-19.
  • Thomas SM, Hayes M, D'Arcangelo G, Armstrong RC, Meyer BE, Zilberstein A, Brugge JS, Halegoua S.Induction of neurite outgrowth by v-src mimics critical aspects of nerve growth factor-induced differentiation.Mol Cell Biol. 1991 Sep;11(9):4739-50.
  • Lord KA, Abdollahi A, Thomas SM, DeMarco M, Brugge JS, Hoffman-Liebermann B, Liebermann DA.Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation.Mol Cell Biol. 1991 Sep;11(9):4371-9.