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Zhi-Min Yuan, M.D. M.S. Ph.D.

Publications

  • Ganapathy S, Xiao S, Yang M, Qi M, Choi DE, Ha CS, Little JB, Yuan ZM.A low-dose arsenic-induced p53 protein-mediated metabolic mechanism of radiotherapy protection.J Biol Chem. 2014 Feb 21;289(8):5340-7.
    24391088
  • Lehtinen MK, Yuan Z, Boag PR, Yang Y, VillÚn J, Becker EB, DiBacco S, de la Iglesia N, Gygi S, Blackwell TK, Bonni A.A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span.Cell. 2006 Jun 2;125(5):987-1001.
    16751106
  • Gu J, Chen D, Rosenblum J, Rubin RM, Yuan ZM.Identification of a sequence element from p53 that signals for Mdm2-targeted degradation.Mol Cell Biol. 2000 Feb;20(4):1243-53.
    10648610
  • Yuan J, Yankner BA.Caspase activity sows the seeds of neuronal death.Nat Cell Biol. 1999 Jun;1(2):E44-5.
    10559896
  • Yuan ZM, Shioya H, Ishiko T, Sun X, Gu J, Huang YY, Lu H, Kharbanda S, Weichselbaum R, Kufe D.p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.Nature. 1999 Jun 24;399(6738):814-7.
    10391251
  • Huang Y, Nakada S, Ishiko T, Utsugisawa T, Datta R, Kharbanda S, Yoshida K, Talanian RV, Weichselbaum R, Kufe D, Yuan ZM.Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage.Mol Cell Biol. 1999 Apr;19(4):2986-97.
    10082566
  • Yuan ZM, Huang Y, Ishiko T, Nakada S, Utsugisawa T, Shioya H, Utsugisawa Y, Yokoyama K, Weichselbaum R, Shi Y, Kufe D.Role for p300 in stabilization of p53 in the response to DNA damage.J Biol Chem. 1999 Jan 22;274(4):1883-6.
    9890940
  • Rodela H, Yuan Z, Johnston MG.Role of protein kinase C in the regulation of pumping activity in bovine mesenteric lymphatic vessels.Lymphology. 1998 Mar;31(1):4-14.
    9561506
  • Yuan ZM, Huang Y, Ishiko T, Nakada S, Utsugisawa T, Kharbanda S, Wang R, Sung P, Shinohara A, Weichselbaum R, Kufe D.Regulation of Rad51 function by c-Abl in response to DNA damage.J Biol Chem. 1998 Feb 13;273(7):3799-802.
    9461559
  • Kharbanda S, Yuan ZM, Weichselbaum R, Kufe D.Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress.Biochim Biophys Acta. 1997 Oct 24;1333(2):O1-7.
    9395286
  • Huang Y, Yuan ZM, Ishiko T, Nakada S, Utsugisawa T, Kato T, Kharbanda S, Kufe DW.Pro-apoptotic effect of the c-Abl tyrosine kinase in the cellular response to 1-beta-D-arabinofuranosylcytosine.Oncogene. 1997 Oct 16;15(16):1947-52.
    9365241
  • Yuan ZM, Utsugisawa T, Huang Y, Ishiko T, Nakada S, Kharbanda S, Weichselbaum R, Kufe D.Inhibition of phosphatidylinositol 3-kinase by c-Abl in the genotoxic stress response.J Biol Chem. 1997 Sep 19;272(38):23485-8.
    9295282
  • Huang Y, Ishiko T, Nakada S, Utsugisawa T, Kato T, Yuan ZM.Role for E2F in DNA damage-induced entry of cells into S phase.Cancer Res. 1997 Sep 1;57(17):3640-3.
    9288762
  • Kharbanda S, Pandey P, Schofield L, Israels S, Roncinske R, Yoshida K, Bharti A, Yuan ZM, Saxena S, Weichselbaum R, Nalin C, Kufe D.Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis.Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6939-42.
    9192670
  • Kharbanda S, Pandey P, Jin S, Inoue S, Bharti A, Yuan ZM, Weichselbaum R, Weaver D, Kufe D.Functional interaction between DNA-PK and c-Abl in response to DNA damage.Nature. 1997 Apr 17;386(6626):732-5.
    9109492
  • Yuan ZM, Huang Y, Ishiko T, Kharbanda S, Weichselbaum R, Kufe D.Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase.Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1437-40.
    9037071
  • Yuan ZM, Huang Y, Whang Y, Sawyers C, Weichselbaum R, Kharbanda S, Kufe D.Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.Nature. 1996 Jul 18;382(6588):272-4.
    8717045