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Roderick T. Bronson, D.V.M.

Lecturer, Department of Pathology, Harvard Medical School

Contact Info

Roderick Bronson
Harvard Medical School
77 Avenue Louis Pasteur
Boston, MA, 02115
Mailstop: Goldenson 141, Rodent Hisopathology Care
Phone: 617-432-0971
Fax: 617-432-2942
roderick_bronson@hms.harvard.edu

Assistant

Not Available.

DF/HCC Program Affiliation

Gastrointestinal Malignancies

DF/HCC Associations

Pathologist, Rodent HistoPathology

Research Abstract

Not Available.

Publications

  • Kucherlapati M, Nguyen A, Kuraguchi M, Yang K, Fan K, Bronson R, Wei K, Lipkin M, Edelmann W, Kucherlapati R.Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies.Oncogene 2007 Apr 23.
    17452984
  • Kuraguchi M, Wang XP, Bronson RT, Rothenberg R, Ohene-Baah NY, Lund JJ, Kucherlapati M, Maas RL, Kucherlapati R.Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.PLoS Genet 2006 Sep 15;2(9):e146.
    17002498
  • McCarty JH, Barry M, Crowley D, Bronson RT, Lacy-Hulbert A, Hynes RO.Genetic Ablation of {alpha}v Integrins in Epithelial Cells of the Eyelid Skin and Conjunctiva Leads to Squamous Cell Carcinoma.Am J Pathol 2008 May 8.
    18467691
  • Epardaud M, Elpek KG, Rubinstein MP, Yonekura AR, Bellemare-Pelletier A, Bronson R, Hamerman JA, Goldrath AW, Turley SJ.Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells.Cancer
    18413767
  • Xu X, Page JL, Surtees JA, Liu H, Lagedrost S, Lu Y, Bronson R, Alani E, Nikitin AY, Weiss RS.Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms.Cancer Res 2008 Apr 15;68(8):2652-60.
    18413732
  • Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, Erkeland SJ, Newman J, Bronson RT, Crowley D, Stone JR, Jaenisch R, Sharp PA, Jacks T.Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters.
    18329372
  • Perera SA, Maser RS, Xia H, McNamara K, Protopopov A, Chen L, Hezel AF, Kim CF, Bronson RT, Castrillon DH, Chin L, Bardeesy N, Depinho RA, Wong KK.Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung
    18283039
  • Kang MS, Soni V, Bronson R, Kieff E.Epstein-Barr virus nuclear antigen 1 does not cause lymphoma in C57BL/6J mice.J Virol 2008 Apr;82(8):4180-3.
    18256159
  • Hu W, Ferris SP, Tweten RK, Wu G, Radaeva S, Gao B, Bronson RT, Halperin JA, Qin X.Rapid conditional targeted ablation of cells expressing human CD59 in transgenic mice by intermedilysin.Nat Med 2008 Jan;14(1):98-103.
    18157141
  • Carroll J, Dey D, Kreisman L, Velupillai P, Dahl J, Telford S, Bronson R, Benjamin T.Receptor-binding and oncogenic properties of polyoma viruses isolated from feral mice.PLoS Pathog 2007 Dec;3(12):e179.
    18085820
  • Li Z, Tognon CE, Godinho FJ, Yasaitis L, Hock H, Herschkowitz JI, Lannon CL, Cho E, Kim SJ, Bronson RT, Perou CM, Sorensen PH, Orkin SH.ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex.Can
    18068631
  • Wong SY, Crowley D, Bronson RT, Hynes RO.Analyses of the role of endogenous SPARC in mouse models of prostate and breast cancer.Clin Exp Metastasis 2008;25(2):109-18.
    18058030
  • Liu Z, Choi SW, Crott JW, Keyes MK, Jang H, Smith DE, Kim M, Laird PW, Bronson R, Mason JB.Mild depletion of dietary folate combined with other B vitamins alters multiple components of the Wnt pathway in mouse colon.J Nutr 2007 Dec;137(12):2701-8.
    18029487
  • Furman C, Sieminski AL, Kwiatkowski AV, Rubinson DA, Vasile E, Bronson RT, Fassler R, Gertler FB.Ena/VASP is required for endothelial barrier function in vivo.J Cell Biol 2007 Nov 19;179(4):761-75.
    17998398
  • Kwiatkowski AV, Rubinson DA, Dent EW, Edward van Veen J, Leslie JD, Zhang J, Mebane LM, Philippar U, Pinheiro EM, Burds AA, Bronson RT, Mori S, Fassler R, Gertler FB.Ena/VASP Is Required for neuritogenesis in the developing cortex.Neuron 2007 Nov 8;56(3):
    17988629
  • Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV, Weissman S, Verdin E, Schwer B.Mammalian Sir2 homolog SIRT3 r
    17923681
  • Lacy-Hulbert A, Smith AM, Tissire H, Barry M, Crowley D, Bronson RT, Roes JT, Savill JS, Hynes RO.Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins.Proc Natl Acad Sci U S A 2007 Oct 2;104(40):15823-8.
    17895374
  • Rasmussen S, Wang Y, Kivisakk P, Bronson RT, Meyer M, Imitola J, Khoury SJ.Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental
    17890734
  • Ji H, Wang Z, Perera SA, Li D, Liang MC, Zaghlul S, McNamara K, Chen L, Albert M, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Thomas RK, Garraway LA, Jänne PA, Johnson BE, Chin L, Wong KK.Mutations in BRAF and KRAS converge on activation of the
    17510423
  • Suh EK, Yang A, Kettenbach A, Bamberger C, Michaelis AH, Zhu Z, Elvin JA, Bronson RT, Crum CP, McKeon F.p63 protects the female germ line during meiotic arrest.Nature 2006 Nov 30;444(7119):624-8.
    17122775
  • Mao J, Ligon KL, Rakhlin EY, Thayer SP, Bronson RT, Rowitch D, McMahon AP.A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway.Cancer Res 2006 Oct 15;66(20):10171-8.
    17047082
  • Kaur A, Sanford HB, Garry D, Lang S, Klumpp SA, Watanabe D, Bronson RT, Lifson JD, Rosati M, Pavlakis GN, Felber BK, Knipe DM, Desrosiers RC.Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge
    16962628
  • Taniguchi CM, Kondo T, Sajan M, Luo J, Bronson R, Asano T, Farese R, Cantley LC, Kahn CR.Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.Cell Metab 2006 May;3(5):343-53.
    16679292
  • Ji H, Zhao X, Yuza Y, Shimamura T, Li D, Protopopov A, Jung BL, McNamara K, Xia H, Glatt KA, Thomas RK, Sasaki H, Horner JW, Eck M, Mitchell A, Sun Y, Al-Hashem R, Bronson RT, Rabindran SK, Discafani CM, Maher E, Shapiro GI, Meyerson M, Wong KK.Epidermal
    16672372
  • Yan CT, Kaushal D, Murphy M, Zhang Y, Datta A, Chen C, Monroe B, Mostoslavsky G, Coakley K, Gao Y, Mills KD, Fazeli AP, Tepsuporn S, Hall G, Mulligan R, Fox E, Bronson R, De Girolami U, Lee C, Alt FW.XRCC4 suppresses medulloblastomas with recurrent transl
    16670198
  • Kucherlapati MH, Nguyen AA, Bronson RT, Kucherlapati RS.Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract.Cancer Res 2006 Apr 1;66(7):3576-83.
    16585182
  • Perides G, Zhuge Y, Lin T, Stins MF, Bronson RT, Wu JK.The fibrinolytic system facilitates tumor cell migration across the blood-brain barrier in experimental melanoma brain metastasis.BMC Cancer 2006;6:56.
    16524486
  • Shen H, McElhinny AS, Cao Y, Gao P, Liu J, Bronson R, Griffin JD, Wu L.The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis.Genes Dev 2006 Mar 15;20(6):675-88.
    16510869
  • Yoo LI, Liu DW, Le Vu S, Bronson RT, Wu H, Yuan J.Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner.Cancer Res 2006 Feb 15;66(4):1929-39.
    16488991
  • Ihrie RA, Bronson RT, Attardi LD.Adult mice lacking the p53/p63 target gene Perp are not predisposed to spontaneous tumorigenesis but display features of ectodermal dysplasia syndromes.Cell Death Differ 2006 Feb 17.
    16485031
  • Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, Cheng HL, Kennedy C, Nunez N, Bronson R, Frendewey D, Auerbach W, Valenzuela D, Karow M, Hottiger M
    16439206
  • Messerli SM, Prabhakar S, Tang Y, Mahmood U, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO.Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2.Hum Gene Ther 2006 Jan;17(1)
    16409122
  • Reilly KM, Broman KW, Bronson RT, Tsang S, Loisel DA, Christy ES, Sun Z, Diehl J, Munroe DJ, Tuskan RG.An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model.Cance
    16397217
  • Lin Q, Clark AB, McCulloch SD, Yuan T, Bronson RT, Kunkel TA, Kucherlapati R.Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice.Cancer Res 2006 Jan 1;66(1):87-94.
    16397220
  • Gilbert SL, Zhang L, Forster ML, Anderson JR, Iwase T, Soliven B, Donahue LR, Sweet HO, Bronson RT, Davisson MT, Wollmann RL, Lahn BT.Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice.Nat Genet 2006 Feb;38(2):245-50.
    16380713
  • Takahashi C, Contreras B, Iwanaga T, Takegami Y, Bakker A, Bronson RT, Noda M, Loda M, Hunt JL, Ewen ME.Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor.Nat Genet 2006 Jan;38(1):118-23.
    16369533
  • Palliser D, Chowdhury D, Wang QY, Lee SJ, Bronson RT, Knipe DM, Lieberman J.An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection.Nature 2006 Jan 5;439(7072):89-94.
    16306938
  • Taverna D, Crowley D, Connolly M, Bronson RT, Hynes RO.A direct test of potential roles for beta3 and beta5 integrins in growth and metastasis of murine mammary carcinomas.Cancer Res 2005 Nov 15;65(22):10324-9.
    16288021
  • Ji H, Houghton AM, Mariani TJ, Perera S, Kim CB, Padera R, Tonon G, McNamara K, Marconcini LA, Hezel A, El-Bardeesy N, Bronson RT, Sugarbaker D, Maser RS, Shapiro SD, Wong KK.K-ras activation generates an inflammatory response in lung tumors.Oncogene 2006
    16288213
  • Jackson EL, Olive KP, Tuveson DA, Bronson R, Crowley D, Brown M, Jacks T.The differential effects of mutant p53 alleles on advanced murine lung cancer.Cancer Res 2005 Nov 15;65(22):10280-8.
    16288016
  • Qin X, Dobarro M, Bedford SJ, Ferris S, Miranda PV, Song W, Bronson RT, Visconti PE, Halperin JA.Further characterization of reproductive abnormalities in mCd59b knockout mice: a potential new function of mCd59 in male reproduction.J Immunol 2005 Nov 15;1
    16272280
  • Wong SY, Haack H, Crowley D, Barry M, Bronson RT, Hynes RO.Tumor-secreted vascular endothelial growth factor-C is necessary for prostate cancer lymphangiogenesis, but lymphangiogenesis is unnecessary for lymph node metastasis.Cancer Res 2005 Nov 1;65(21):
    16267000
  • Yi C, McCarty JH, Troutman SA, Eckman MS, Bronson RT, Kissil JL.Loss of the putative tumor suppressor band 4.1B/Dal1 gene is dispensable for normal development and does not predispose to cancer.Mol Cell Biol 2005 Nov;25(22):10052-9.
    16260618
  • Fujiwara T, Bandi M, Nitta M, Ivanova EV, Bronson RT, Pellman D.Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells.Nature 2005 Oct 13;437(7061):1043-7.
    16222300
  • Sullivan BM, Jobe O, Lazarevic V, Vasquez K, Bronson R, Glimcher LH, Kramnik I.Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production.J Immunol 2005 Oc
    16177104
  • Jiang W, Anderson MS, Bronson R, Mathis D, Benoist C.Modifier loci condition autoimmunity provoked by Aire deficiency.J Exp Med 2005 Sep 19;202(6):805-15.
    16172259
  • Zhang YW, Su Y, Lanning N, Swiatek PJ, Bronson RT, Sigler R, Martin RW, Vande Woude GF.Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease.Proc Natl Acad Sci U S A 2005 Aug 16;102(33):11740-5.
    16087873
  • Marques MR, Horner JS, Ihrie RA, Bronson RT, Attardi LD.Mice lacking the p53/p63 target gene Perp are resistant to papilloma development.Cancer Res 2005 Aug 1;65(15):6551-6.
    16061634
  • Collin GB, Cyr E, Bronson R, Marshall JD, Gifford EJ, Hicks W, Murray SA, Zheng QY, Smith RS, Nishina PM, Naggert JK.Alms1-disrupted mice recapitulate human Alström syndrome.Hum Mol Genet 2005 Aug 15;14(16):2323-33.
    16000322
  • Ludlow A, Yee KO, Lipman R, Bronson R, Weinreb P, Huang X, Sheppard D, Lawler J.Characterization of integrin beta6 and thrombospondin-1 double-null mice.J Cell Mol Med 2005 Apr-Jun;9(2):421-37.
    15963261
  • Kim CF, Jackson EL, Woolfenden AE, Lawrence S, Babar I, Vogel S, Crowley D, Bronson RT, Jacks T.Identification of bronchioalveolar stem cells in normal lung and lung cancer.Cell 2005 Jun 17;121(6):823-35.
    15960971
  • Asher DR, Cerny AM, Weiler SR, Horner JW, Keeler ML, Neptune MA, Jones SN, Bronson RT, Depinho RA, Finberg RW.Coxsackievirus and adenovirus receptor is essential for cardiomyocyte development.Genesis 2005 Jun;42(2):77-85.
    15864812
  • Ihrie RA, Marques MR, Nguyen BT, Horner JS, Papazoglu C, Bronson RT, Mills AA, Attardi LD.Perp is a p63-regulated gene essential for epithelial integrity.Cell 2005 Mar 25;120(6):843-56.
    15797384
  • Kang MS, Lu H, Yasui T, Sharpe A, Warren H, Cahir-McFarland E, Bronson R, Hung SC, Kieff E.Epstein-Barr virus nuclear antigen 1 does not induce lymphoma in transgenic FVB mice.Proc Natl Acad Sci U S A 2005 Jan 18;102(3):820-5.
    15640350
  • Torres-Arzayus MI, De Mora JF, Yuan J, Vazquez F, Bronson R, Rue M, Sellers WR, Brown M.High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene.Cancer Cell 2004 Sep;6(3):263-74.
    15380517
  • Kozar K, Ciemerych MA, Rebel VI, Shigematsu H, Zagozdzon A, Sicinska E, Geng Y, Yu Q, Bhattacharya S, Bronson RT, Akashi K, Sicinski P.Mouse development and cell proliferation in the absence of D-cyclins.Cell 2004 Aug 20;118(4):477-91.
    15315760
  • Araki T, Mohi MG, Ismat FA, Bronson RT, Williams IR, Kutok JL, Yang W, Pao LI, Gilliland DG, Epstein JA, Neel BG.Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.Nat Med 2004 Aug;10(8):849-57.
    15273746
  • Mitsiades CS, Mitsiades NS, Bronson RT, Chauhan D, Munshi N, Treon SP, Maxwell CA, Pilarski L, Hideshima T, Hoffman RM, Anderson KC.Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical impli
    14583463
  • Cheng HL, Mostoslavsky R, Saito S, Manis JP, Gu Y, Patel P, Bronson R, Appella E, Alt FW, Chua KF.Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice.Proc Natl Acad Sci U S A 2003 Sep 16;100(19):10794-9.
    12960381
  • Geng Y, Yu Q, Sicinska E, Das M, Schneider JE, Bhattacharya S, Rideout WM, Bronson RT, Gardner H, Sicinski P.Cyclin E ablation in the mouse.Cell 2003 Aug 22;114(4):431-43.
    12941272
  • Bassing CH, Suh H, Ferguson DO, Chua KF, Manis J, Eckersdorff M, Gleason M, Bronson R, Lee C, Alt FW.Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors.Cell 2003 Aug 8;114(3):359-70.
    12914700
  • Yan C, Martinez-Quiles N, Eden S, Shibata T, Takeshima F, Shinkura R, Fujiwara Y, Bronson R, Snapper SB, Kirschner MW, Geha R, Rosen FS, Alt FW.WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility.EMBO J 2003 Jul
    12853475
  • Kim YM, Sachs T, Asavaroengchai W, Bronson R, Sykes M.Graft-versus-host disease can be separated from graft-versus-lymphoma effects by control of lymphocyte trafficking with FTY720.J Clin Invest 2003 Mar;111(5):659-69.
    12618520
  • Zinkel SS, Ong CC, Ferguson DO, Iwasaki H, Akashi K, Bronson RT, Kutok JL, Alt FW, Korsmeyer SJ.Proapoptotic BID is required for myeloid homeostasis and tumor suppression.Genes Dev 2003 Jan 15;17(2):229-39.
    12533511
  • Hock H, Hamblen MJ, Rooke HM, Traver D, Bronson RT, Cameron S, Orkin SH.Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation.Immunity 2003 Jan;18(1):109-20.
    12530980
  • Ciemerych MA, Kenney AM, Sicinska E, Kalaszczynska I, Bronson RT, Rowitch DH, Gardner H, Sicinski P.Development of mice expressing a single D-type cyclin.Genes Dev 2002 Dec 15;16(24):3277-89.
    12502747
  • Inoue A, Seidel MG, Wu W, Kamizono S, Ferrando AA, Bronson RT, Iwasaki H, Akashi K, Morimoto A, Hitzler JK, Pestina TI, Jackson CW, Tanaka R, Chong MJ, McKinnon PJ, Inukai T, Grosveld GC, Look AT.Slug, a highly conserved zinc finger transcriptional repres
    12398892
  • Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D.Projection of an immunological self shadow within the thymus by the aire protein.Science 2002 Nov 15;298(5597):1395-401.
    12376594
  • Girnun GD, Smith WM, Drori S, Sarraf P, Mueller E, Eng C, Nambiar P, Rosenberg DW, Bronson RT, Edelmann W, Kucherlapati R, Gonzalez FJ, Spiegelman BM.APC-dependent suppression of colon carcinogenesis by PPARgamma.Proc Natl Acad Sci U S A 2002 Oct 15;99(21
    12370429
  • Mapara MY, Kim YM, Wang SP, Bronson R, Sachs DH, Sykes M.Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells.Blood 2002 Sep 1;100(5):19
    12176915
  • Felbor U, Kessler B, Mothes W, Goebel HH, Ploegh HL, Bronson RT, Olsen BR.Neuronal loss and brain atrophy in mice lacking cathepsins B and L.Proc Natl Acad Sci U S A 2002 Jun 11;99(12):7883-8.
    12048238
  • Gounari F, Signoretti S, Bronson R, Klein L, Sellers WR, Kum J, Siermann A, Taketo MM, von Boehmer H, Khazaie K.Stabilization of beta-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of
    12037666
  • Young KA, Berry ML, Mahaffey CL, Saionz JR, Hawes NL, Chang B, Zheng QY, Smith RS, Bronson RT, Nelson RJ, Simpson EM.Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent.Behav Brain Res 2002 May 14;132
    11997145
  • Weber GF, Bronson RT, Ilagan J, Cantor H, Schmits R, Mak TW.Absence of the CD44 gene prevents sarcoma metastasis.Cancer Res 2002 Apr 15;62(8):2281-6.
    11956084
  • Yang H, Williams BO, Hinds PW, Shih TS, Jacks T, Bronson RT, Livingston DM.Tumor suppression by a severely truncated species of retinoblastoma protein.Mol Cell Biol 2002 May;22(9):3103-10.
    11940667
  • Cloud JE, Rogers C, Reza TL, Ziebold U, Stone JR, Picard MH, Caron AM, Bronson RT, Lees JA.Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo.Mol Cell Biol 2002 Apr;22(8):2663-72.
    11909960
  • Herron BJ, Lu W, Rao C, Liu S, Peters H, Bronson RT, Justice MJ, McDonald JD, Beier DR.Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.Nat Genet 2002 Feb;30(2):185-9.
    11818962
  • Miyoshi K, Shillingford JM, Le Provost F, Gounari F, Bronson R, von Boehmer H, Taketo MM, Cardiff RD, Hennighausen L, Khazaie K.Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and
    11773619
  • Steele-Perkins G, Fang W, Yang XH, Van Gele M, Carling T, Gu J, Buyse IM, Fletcher JA, Liu J, Bronson R, Chadwick RB, de la Chapelle A, Zhang X, Speleman F, Huang S.Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyl
    11544182
  • Yu Q, Geng Y, Sicinski P.Specific protection against breast cancers by cyclin D1 ablation.Nature 2001 Jun 28;411(6841):1017-21.
    11429595
  • Imanishi Y, Hosokawa Y, Yoshimoto K, Schipani E, Mallya S, Papanikolaou A, Kifor O, Tokura T, Sablosky M, Ledgard F, Gronowicz G, Wang TC, Schmidt EV, Hall C, Brown EM, Bronson R, Arnold A.Primary hyperparathyroidism caused by parathyroid-targeted overexp
    11342573
  • Geng Y, Yu Q, Sicinska E, Das M, Bronson RT, Sicinski P.Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice.Proc Natl Acad Sci U S A 2001 Jan 2;98(1):194-9.
    11134518
  • O'Brien SP, Seipel K, Medley QG, Bronson R, Segal R, Streuli M.Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos.Proc Natl Acad Sci U S A 2000 Oct 24;97(22):12074-8.
    11050238
  • Nikolic B, Lee S, Bronson RT, Grusby MJ, Sykes M.Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets.J Clin Invest 2000 May;105(9):1289-98.
    10792004
  • Kung AL, Rebel VI, Bronson RT, Ch'ng LE, Sieff CA, Livingston DM, Yao TP.Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP.Genes Dev 2000 Feb 1;14(3):272-7.
    10673499
  • Velupillai P, Yoshizawa I, Dey DC, Nahill SR, Carroll JP, Bronson RT, Benjamin TL.Wild-derived inbred mice have a novel basis of susceptibility to polyomavirus-induced tumors.J Virol 1999 Dec;73(12):10079-85.
    10559322
  • Geng Y, Whoriskey W, Park MY, Bronson RT, Medema RH, Li T, Weinberg RA, Sicinski P.Rescue of cyclin D1 deficiency by knockin cyclin E.Cell 1999 Jun 11;97(6):767-77.
    10380928
  • Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, Bronson RT, Tabin C, Sharpe A, Caput D, Crum C, McKeon F.p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development.Nature 1999 Apr 22;398(6729):714-8.
    10227294
  • Baba TW, Liska V, Khimani AH, Ray NB, Dailey PJ, Penninck D, Bronson R, Greene MF, McClure HM, Martin LN, Ruprecht RM.Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques.Nat Med 1999 Feb;5(2):194-203.
    9930868
  • Carroll JP, Fung JS, Bronson RT, Razvi E, Benjamin TL.Radiation-resistant and radiation-sensitive forms of host resistance to polyomavirus.J Virol 1999 Feb;73(2):1213-8.
    9882323
  • Gao Y, Sun Y, Frank KM, Dikkes P, Fujiwara Y, Seidl KJ, Sekiguchi JM, Rathbun GA, Swat W, Wang J, Bronson RT, Malynn BA, Bryans M, Zhu C, Chaudhuri J, Davidson L, Ferrini R, Stamato T, Orkin SH, Greenberg ME, Alt FW.A critical role for DNA end-joining pro
    9875844
  • Pear WS, Miller JP, Xu L, Pui JC, Soffer B, Quackenbush RC, Pendergast AM, Bronson R, Aster JC, Scott ML, Baltimore D.Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced
    9808572
  • Yoshizawa I, Bronson R, Dorf ME, Abromson-Leeman S.T-cell responses to myelin basic protein in normal and MBP-deficient mice.J Neuroimmunol 1998 Apr 15;84(2):131-8.
    9628454
  • Yao TP, Oh SP, Fuchs M, Zhou ND, Ch'ng LE, Newsome D, Bronson RT, Li E, Livingston DM, Eckner R.Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.Cell 1998 May 1;93(3):361-72.
    9590171
  • Chae T, Kwon YT, Bronson R, Dikkes P, Li E, Tsai LH.Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality.Neuron 1997 Jan;18(1):29-42.
    9010203
  • Sicinski P, Donaher JL, Geng Y, Parker SB, Gardner H, Park MY, Robker RL, Richards JS, McGinnis LK, Biggers JD, Eppig JJ, Bronson RT, Elledge SJ, Weinberg RA.Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis.Nature
    8945475
  • Brown JR, Ye H, Bronson RT, Dikkes P, Greenberg ME.A defect in nurturing in mice lacking the immediate early gene fosB.Cell 1996 Jul 26;86(2):297-309.
    8706134
  • Yamasaki L, Jacks T, Bronson R, Goillot E, Harlow E, Dyson NJ.Tumor induction and tissue atrophy in mice lacking E2F-1.Cell 1996 May 17;85(4):537-48.
    8653789
  • Sicinski P, Donaher JL, Parker SB, Li T, Fazeli A, Gardner H, Haslam SZ, Bronson RT, Elledge SJ, Weinberg RA.Cyclin D1 provides a link between development and oncogenesis in the retina and breast.Cell 1995 Aug 25;82(4):621-30.
    7664341