Jennifer R. Brown, MD, PhD

Publications

• Brown JR.Insulin Receptor Activation in Deletion 11q Chronic Lymphocytic Leukemia.Clin Cancer Res. 2011 Mar 22.
  21427241
• Friese CR, Earle CC, Magazu LS, Brown JR, Neville BA, Hevelone ND, Richardson LC, Abel GA.Timeliness and quality of diagnostic care for medicare recipients with chronic lymphocytic leukemia.Cancer. 2011 Apr 1;117(7):1470-7.
  21425148
• Li S, Moffett HF, Lu J, Werner L, Zhang H, Ritz J, Neuberg D, Wucherpfennig KW, Brown JR, Novina CD.MicroRNA Expression Profiling Identifies Activated B Cell Status in Chronic Lymphocytic Leukemia Cells.PLoS ONE. 2011;6(3):e16956.
  21408091
• Hu W, Ge X, You T, Xu T, Zhang J, Wu G, Peng Z, Chorev M, Aktas BH, Halperin JA, Brown JR, Qin X.Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis.Cancer Res. 2011 Mar 15;71(6):2298-307.
  21252115
• Hartlerode A, Odate S, Shim I, Brown J, Scully R.Cell Cycle-Dependent Induction of Homologous Recombination by a Tightly Regulated I-SceI Fusion Protein.PLoS ONE. 2011;6(3):e16501.
  21408059
• Amrein PC, Attar EC, Takvorian RW, Hochberg EP, Ballen KK, Leahy KM, Fisher DE, Lacasce AS, Jacobsen ED, Armand P, Hasserjian RP, Werner L, Neuberg DS, Brown JR.Phase II Study of Dasatinib in Relapsed or Refractory Chronic Lymphocytic Leukemia.Clin Cancer
  21402714
• Abou-Nassar K, Brown JR.Novel agents for the treatment of chronic lymphocytic leukemia.Clin Adv Hematol Oncol. 2010 Dec;8(12):886-95. Review.
  21326166
• Wierda WG, Kipps TJ, Keating MJ, Brown JR, Gribben JG, Browning M, Rassenti LZ, Greaves AW, Neuberg D, O'Brien SM, .Self-administered, subcutaneous alemtuzumab to treat residual disease in patients with chronic lymphocytic leukemia.Cancer. 2011 Jan 1
  20806349
• Smoley SA, Van Dyke DL, Kay NE, Heerema NA, Dell' Aquila ML, Dal Cin P, Koduru P, Aviram A, Rassenti L, Byrd JC, Rai KR, Brown JR, Greaves AW, Eckel-Passow J, Neuberg D, Kipps TJ, Dewald GW.Standardization of fluorescence in situ hybridization studies
  21156226
• Heerema NA, Byrd JC, Dal Cin PS, Dell' Aquila ML, Koduru PR, Aviram A, Smoley SA, Rassenti LZ, Greaves AW, Brown JR, Rai KR, Kipps TJ, Kay NE, Van Dyke DL, .Stimulation of chronic lymphocytic leukemia cells with CpG oligodeoxynucleotide gives consist
  21156225
• Danilov AV, Danilova OV, Brown JR, Rabinowitz A, Klein AK, Huber BT.Dipeptidyl peptidase 2 apoptosis assay determines the B-cell activation stage and predicts prognosis in chronic lymphocytic leukemia.Exp Hematol. 2010 Dec;38(12):1167-77.
  20817072
• Brown JR, Abramson J, Hochberg E, Mikler E, Dalton V, Werner L, Reynolds H, Thompson C, McDonough SM, Kuang Y, Ritz J, Neuberg D, Freedman AS.A phase I study of lenalidomide in combination with fludarabine and rituximab in previously untreated CLL/SLL.Leu
  20844565
• Friese CR, Earle CC, Magazu LS, Brown JR, Neville BA, Hevelone ND, Richardson LC, Abel GA.Timeliness and quality of diagnostic care for medicare recipients with chronic lymphocytic leukemia.Cancer. 2010 Nov 8.
  21061368
• Wierda WG, Chiorazzi N, Dearden C, Brown JR, Montserrat E, Shpall E, Stilgenbauer S, Muneer S, Grever M.Chronic lymphocytic leukemia: new concepts for future therapy.Clin Lymphoma Myeloma Leuk. 2010 Oct;10(5):369-78. Review.
  21030350
• Setlur SR, Ihm C, Tchinda J, Shams S, Werner L, Cho EK, Thompson C, Phillips K, Rassenti LZ, Kipps TJ, Neuberg D, Freedman AS, Lee C, Brown JR.Comparison of familial and sporadic chronic lymphocytic leukaemia using high resolution array comparative genomi
  20812997
• Brown JR.Immunomodulators in chronic lymphocytic leukemia: where does lenalidomide belong?.Leuk Lymphoma. 2010 Aug;51(8):1382-5.
  20624030
• Brown JR, Callaghan PT.Measurement of vorticity diffusion by NMR microscopy.J Magn Reson. 2010 May;204(1):21-5.
  20189854
• Yoda A, Yoda Y, Chiaretti S, Bar-Natan M, Mani K, Rodig SJ, West N, Xiao Y, Brown JR, Mitsiades C, Sattler M, Kutok JL, DeAngelo DJ, Wadleigh M, Piciocchi A, Dal Cin P, Bradner JE, Griffin JD, Anderson KC, Stone RM, Ritz J, Foà R, Aster JC, Frank DA, Wei
  20018760
• Brown JR,Friedberg JW,Feng Y,Scofield S,Phillips K,Dal Cin P,Joyce R,Takvorian RW,Fisher DC,Fisher RI,Liesveld J,Marquis D,Neuberg D,Freedman AS.A phase 2 study of concurrent fludarabine and rituximab for the treatment of marginal zone lymphomas.British J
  19344412
• Brown JR, Freedman AS.ASCT in follicular lymphoma.Nat Rev Clin Oncol. 2009 Jul;6(7):380-2.
  19561632
• Armand P,Gannamaneni S,Kim HT,Cutler CS,Ho VT,Koreth J,Alyea EP,LaCasce AS,Jacobsen ED,Fisher DC,Brown JR,Canellos GP,Freedman AS,Soiffer RJ,Antin JH.Improved survival in lymphoma patients receiving sirolimus for graft-versus-host disease prophylaxis afte
  19001324
• Brown JR, Levine RL, Thompson C, Basile G, Gilliland DG, Freedman AS.Systematic genomic screen for tyrosine kinase mutations in CLL.Leukemia. 2008 Oct;22(10):1966-9.
  18754031
• Brown JR,Neuberg D,Phillips K,Reynolds H,Silverstein J,Clark JC,Ash M,Thompson C,Fisher DC,Jacobsen E,LaCasce AS,Freedman AS.Prevalence of familial malignancy in a prospectively screened cohort of patients with lymphoproliferative disorders.British Journa
  18729853
• Rassenti LZ,Jain S,Keating MJ,Wierda WG,Grever MR,Byrd JC,Kay NE,Brown JR,Gribben JG,Neuberg DS,He F,Greaves AW,Rai KR,Kipps TJ.Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leuk
  18577710
• Ruddy KJ,Wu D,Brown JR.Pseudohyperkalemia in chronic lymphocytic leukemia.J Clin Oncol. 2008 Jun 1;26(16):2781-2.
  18509189
• Armand P, Kim HT, Ho VT, Cutler CS, Koreth J, Antin JH, LaCasce AS, Jacobsen ED, Fisher DC, Brown JR, Canellos GP, Freedman AS, Soiffer RJ, Alyea EP.Allogeneic transplantation with reduced-intensity conditioning for Hodgkin and non-Hodgkin lymphoma: impor
  18342784
• Ghia EM, Jain S, Widhopf GF 2nd, Rassenti LZ, Keating MJ, Wierda WG, Gribben JG, Brown JR, Rai KR, Byrd JC, Kay NE, Greaves AW, Kipps TJ.Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post
  18326815
• Tsimberidou AM, Wierda WG, Plunkett W, Kurzrock R, O'Brien S, Wen S, Ferrajoli A, Ravandi-Kashani F, Garcia-Manero G, Estrov Z, Kipps TJ, Brown JR, Fiorentino A, Lerner S, Kantarjian HM, Keating MJ.Phase I-II study of oxaliplatin, fludarabine, cytarab
  18182662
• Engel RH, Brown JA, Von Roenn JH, O'Regan RM, Bergan R, Badve S, Rademaker A, Gradishar WJ.A phase II study of single agent bortezomib in patients with metastatic breast cancer: a single institution experience.Cancer Invest. 2007 Dec;25(8):733-7.
  17952740
• Brown JR, Feng Y, Gribben JG, Neuberg D, Fisher DC, Mauch P, Nadler LM, Freedman AS.Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission.Biol Blood Marrow Transplant. 2007 Sep;13(9):1057-65.
  17697968
• Sterman DH, Recio A, Carroll RG, Gillespie CT, Haas A, Vachani A, Kapoor V, Sun J, Hodinka R, Brown JL, Corbley MJ, Parr M, Ho M, Pastan I, Machuzak M, Benedict W, Zhang XQ, Lord EM, Litzky LA, Heitjan DF, June CH, Kaiser LR, Vonderheide RH, Albelda SM, K
  17671130
• Chen YB, Yu H, Gillani A, Brown JR.AIDS-associated plasmablastic lymphoma presenting at the insertion site of a peritoneal dialysis catheter.J Clin Oncol. 2007 Jul 20;25(21):3176-8.
  17634499
• Del Gaizo Moore V, Brown JR, Certo M, Love TM, Novina CD, Letai A.Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.J Clin Invest. 2007 Jan;117(1):112-21.
  17200714
• Brown JR, Kim HT, Li S, Stephans K, Fisher DC, Cutler C, Ho V, Lee SJ, Milford EL, Ritz J, Antin JH, Soiffer RJ, Gribben JG, Alyea EP.Predictors of improved progression-free survival after nonmyeloablative allogeneic stem cell transplantation for advanced
  17084369
• Brown JR, Yeckes H, Friedberg JW, Neuberg D, Kim H, Nadler LM, Freedman AS.Increasing incidence of late second malignancies after conditioning with cyclophosphamide and total-body irradiation and autologous bone marrow transplantation for non-Hodgkin'
  15753460
• Brown JR, Skarin AT.Clinical mimics of lymphoma.Oncologist. 2004;9(4):406-16.
  15266094
• Brown JR, Weng AP, Freedman AS.Hodgkin disease associated with T-cell non-Hodgkin lymphomas: case reports and review of the literature.Am J Clin Pathol. 2004 May;121(5):701-8.
  15151210
• Brown JR, Gaudet G, Friedberg JW, Neuberg D, Mauch P, Kutok JL, Takvorian T, Fisher DC, Gribben JG, Kim H, Nadler LM, Freedman AS.Autologous bone marrow transplantation for marginal zone non-Hodgkin's lymphoma.Leuk Lymphoma. 2004 Feb;45(2):315-20.
  15101717
• Brown JR, Demetri GD.Challenges in the development of platelet growth factors: low expectations for low counts.Curr Hematol Rep. 2002 Nov;1(2):110-8.
  12901132
• Brown JR, Kuter DJ.The effect of unfractionated vs. low molecular weight heparin on tissue factor pathway inhibitor levels in hospital inpatients.Thromb Haemost. 2001 Jun;85(6):979-85.
  11434705
• Brown JR, Nigh E, Lee RJ, Ye H, Thompson MA, Saudou F, Pestell RG, Greenberg ME.Fos family members induce cell cycle entry by activating cyclin D1.Mol Cell Biol. 1998 Sep;18(9):5609-19.
  9710644
• Brown JR, Ye H, Bronson RT, Dikkes P, Greenberg ME.A defect in nurturing in mice lacking the immediate early gene fosB.Cell. 1996 Jul 26;86(2):297-309.
  8706134