• Home
  • News
  • Calendar
  • About DF/HCC
  • Membership
  • Visitor Center

Patricia A. D'Amore, PhD, MBA, FARVO

Publications

  • Shahrabi-Farahani S, Wang L, Zwaans BM, Santana JM, Shimizu A, Takashima S, Kreuter M, Coultas L, D'Amore PA, Arbeit JM, Akslen LA, Bielenberg DR.Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas.Lab Invest. 2014 May 5.
    24791743
  • Walshe TE, dela Paz NG, D'Amore PA.The role of shear-induced transforming growth factor-β signaling in the endothelium.Arterioscler Thromb Vasc Biol. 2013 Nov;33(11):2608-17.
    23968981
  • Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW.Epoxyeicosanoids promote organ and tissue regeneration.Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13528-33.
    23898174
  • Bagchi M, Kim LA, Boucher J, Walshe TE, Kahn CR, D'Amore PA.Vascular endothelial growth factor is important for brown adipose tissue development and maintenance.FASEB J. 2013 Aug;27(8):3257-71.
    23682123
  • Bielenberg DR, D'Amore PA.All vessels are not created equal.Am J Pathol. 2013 Apr;182(4):1087-91.
    23422091
  • Jia D, Hasso SM, Chan J, Filingeri D, D'Amore PA, Rice L, Pampo C, Siemann DW, Zurakowski D, Rodig SJ, Moses MA.Transcriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo.Blood. 2013 Jan 24;121(4):707-15.
    23212515
  • Kim LA, D'Amore PA.A brief history of anti-VEGF for the treatment of ocular angiogenesis.Am J Pathol. 2012 Aug;181(2):376-9.
    22749677
  • Dela Paz NG, Walshe TE, Leach LL, Saint-Geniez M, D'Amore PA.Role of shear-stress-induced VEGF expression in endothelial cell survival.J Cell Sci. 2012 Feb 15;125(Pt 4):831-43.
    22399811
  • Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC.Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice.J Clin Invest. 2012 Jan 3;122(1):178-91.
    22182838
  • Cao Y, Arbiser J, D'Amato RJ, D'Amore PA, Ingber DE, Kerbel R, Klagsbrun M, Lim S, Moses MA, Zetter B, Dvorak H, Langer R.Forty-year journey of angiogenesis translational research.Sci Transl Med. 2011 Dec 21;3(114):114rv3.
    22190240
  • Patel-Hett S, D'Amore PA.Signal transduction in vasculogenesis and developmental angiogenesis.Int J Dev Biol. 2011;55(4-5):353-63. Review.
    21732275
  • Lee YJ, Karl DL, Maduekwe UN, Rothrock C, Ryeom S, D'Amore PA, Yoon SS.Differential Effects of VEGFR-1 and VEGFR-2 Inhibition on Tumor Metastases Based on Host Organ Environment.Cancer Res. 2010 Nov 1;70(21):8357-67.
    20978198
  • Bryan BA, Dennstedt E, Mitchell DC, Walshe TE, Noma K, Loureiro R, Saint-Geniez M, Campaigniac JP, Liao JK, D'Amore PA.RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis.FASEB J. 2010 Sep;24(9):3186-95.
    20400538
  • Fukumoto A, Maruyama K, Walsh T, Kajiya K, Hamuro J, D'Amore PA, Kinoshita S.Intracellular Thiol Redox Status Regulates Lymphatic Vessel Growth in the Cornea and Dictates Corneal Limbal Graft Survival.Invest Ophthalmol Vis Sci. 2010 May;51(5):2450-8.
    20042658
  • D'Amore PA.Editorial.Microvasc Res. 2010 May;79(3):161.
    20171233
  • Saint-Geniez M, Kurihara T, Sekiyama E, Maldonado AE, D'Amore PA.An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris.Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18751-6.
    19841260
  • Nieves BJ,D'Amore PA,Bryan BA.The function of vascular endothelial growth factor.Biofactors.;35(4):332-7. Review.
    19415738
  • Walshe TE,Dole VS,Maharaj AS,Patten IS,Wagner DD,D'Amore PA.Inhibition of VEGF or TGF-{beta} Signaling Activates Endothelium and Increases Leukocyte Rolling.Arterioscler Thromb Vasc Biol. 2009 Aug;29(8):1185-92.
    19461051
  • Walshe TE,Saint-Geniez M,Maharaj AS,Sekiyama E,Maldonado AE,D'Amore PA.TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature.PLoS ONE. 2009;4(4):e5149.
    19340291
  • Saint-Geniez M,Maharaj AS,Walshe TE,Tucker BA,Sekiyama E,Kurihara T,Darland DC,Young MJ,D'Amore PA.Endogenous VEGF is required for visual function: evidence for a survival role on muller cells and photoreceptors.PLoS ONE. 2008;3(11):e3554.
    18978936
  • dela Paz NG,D'Amore PA.Arterial versus venous endothelial cells.Cell Tissue Res. 2009 Jan;335(1):5-16. Review.
    18972135
  • Walshe TE, D'Amore PA.The Role of Hypoxia in Vascular Injury and Repair.Annu Rev Pathol. 2008;3:615-43. Review.
    18039132
  • Fernando NT, Koch M, Rothrock C, Gollogly LK, D'Amore PA, Ryeom S, Yoon SS.Tumor escape from endogenous, extracellular matrix-associated angiogenesis inhibitors by up-regulation of multiple proangiogenic factors.Clin Cancer Res. 2008 Mar 1;14(5):1529-39.
    18316578
  • Chao W, D'Amore PA.IGF2: Epigenetic regulation and role in development and disease.Cytokine Growth Factor Rev. 2008 Apr;19(2):111-20. Review.
    18308616
  • Bryan BA, Walshe TE, Mitchell DC, Havumaki JS, Saint-Geniez M, Maharaj AS, Maldonado AE, D'Amore PA.Coordinated Vascular Endothelial Growth Factor Expression and Signaling During Skeletal Myogenic Differentiation.Mol Biol Cell. 2008 Mar;19(3):994-1006.
    18094043
  • Maharaj AS, Walshe TE, Saint-Geniez M, Venkatesha S, Maldonado AE, Himes NC, Matharu KS, Karumanchi SA, D'Amore PA.VEGF and TGF-{beta} are required for the maintenance of the choroid plexus and ependyma.J Exp Med. 2008 Feb 18;205(2):491-501.
    18268040
  • Maharaj AS, D'Amore PA.Roles for VEGF in the adult.Microvasc Res.;74(2-3):100-13. Review.
    17532010
  • Harper J, Yan L, Loureiro RM, Wu I, Fang J, D'Amore PA, Moses MA.Repression of vascular endothelial growth factor expression by the zinc finger transcription factor ZNF24.Cancer Res. 2007 Sep 15;67(18):8736-41.
    17875714
  • D'Amore PA.Vascular endothelial cell growth factor-a: not just for endothelial cells anymore.Am J Pathol. 2007 Jul;171(1):14-8.
    17591949
  • Bryan BA, D'Amore PA.What tangled webs they weave: Rho-GTPase control of angiogenesis.Cell Mol Life Sci. 2007 Aug;64(16):2053-65. Review.
    17530172
  • D'Amore PA.Vascular Endothelial Cell Growth Factor-A. Not Just for Endothelial Cells Anymore.Am J Pathol. 2007 May 18.
    17513338
  • Ramsauer M, D'Amore PA.Contextual role for angiopoietins and TGFbeta1 in blood vessel stabilization.J Cell Sci. 2007 May 15;120(Pt 10):1810-7.
    17502485
  • Goodwin AM, Kitajewski J, D'Amore PA.Wnt1 and Wnt5a affect endothelial proliferation and capillary length; Wnt2 does not.Growth Factors. 2007 Feb;25(1):25-32.
    17454147
  • Maruyama K, Asai J, Ii M, Thorne T, Losordo DW, D'Amore PA.Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing.Am J Pathol. 2007 Apr;170(4):1178-91.
    17392158
  • Banerjee S, Sengupta K, Dhar K, Mehta S, D'Amore PA, Dhar G, Banerjee SK.Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1.Mol Carcinog. 2006 Nov;45(11):871-80.
    16847823
  • Goodwin AM, Sullivan KM, D'Amore PA.Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling.Dev Dyn. 2006 Nov;235(11):3110-20.
    17013885
  • Saint-Geniez M, Maldonado AE, D'Amore PA.VEGF expression and receptor activation in the choroid during development and in the adult.Invest Ophthalmol Vis Sci. 2006 Jul;47(7):3135-42.
    16799060
  • Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, Kim YM, Bdolah Y, Lim KH, Yuan HT, Libermann TA, Stillman IE, Roberts D, D'Amore PA, Epstein FH, Sellke FW, Romero R, Sukhatme VP, Letarte M, Karumanchi SA.Soluble endoglin contributes to the pathogenesis of preeclampsia.Nat Med. 2006 Jun;12(6):642-9.
    16751767
  • Maharaj AS, Saint-Geniez M, Maldonado AE, D'Amore PA.Vascular endothelial growth factor localization in the adult.Am J Pathol. 2006 Feb;168(2):639-48.
    16436677
  • Maruyama K, Ii M, Cursiefen C, Jackson DG, Keino H, Tomita M, Van Rooijen N, Takenaka H, D'Amore PA, Stein-Streilein J, Losordo DW, Streilein JW.Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages.J Clin Invest. 2005 Sep;115(9):2363-72.
    16138190
  • Detwiller KY, Fernando NT, Segal NH, Ryeom SW, D'Amore PA, Yoon SS.Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A.Cancer Res. 2005 Jul 1;65(13):5881-9.
    15994966
  • Darland DC, D'Amore PA.Blood vessel maturation: vascular development comes of age.J Clin Invest. 1999 Jan;103(2):157-8.
    9916126
  • Hirschi KK, Rohovsky SA, D'Amore PA.PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate.J Cell Biol. 1998 May 4;141(3):805-14.
    9566978
  • Beck L, D'Amore PA.Vascular development: cellular and molecular regulation.FASEB J. 1997 Apr;11(5):365-73.
    9141503
  • Folkman J, D'Amore PA.Blood vessel formation: what is its molecular basis?.Cell. 1996 Dec 27;87(7):1153-5.
    8980221
  • Ku PT, D'Amore PA.Regulation of basic fibroblast growth factor (bFGF) gene and protein expression following its release from sublethally injured endothelial cells.J Cell Biochem. 1995 Jul;58(3):328-43.
    7593255
  • Shima DT, Adamis AP, Ferrara N, Yeo KT, Yeo TK, Allende R, Folkman J, D'Amore PA.Hypoxic induction of endothelial cell growth factors in retinal cells: identification and characterization of vascular endothelial growth factor (VEGF) as the mitogen.Mol Med. 1995 Jan;1(2):182-93.
    8529097
  • D'Amore PA.Mechanisms of retinal and choroidal neovascularization.Invest Ophthalmol Vis Sci. 1994 Nov;35(12):3974-9.
    7525506
  • Kostyk SK, D'Amore PA, Herman IM, Wagner JA.Optic nerve injury alters basic fibroblast growth factor localization in the retina and optic tract.J Neurosci. 1994 Mar;14(3 Pt 2):1441-9.
    7510332
  • Saunders KB, D'Amore PA.An in vitro model for cell-cell interactions.In Vitro Cell Dev Biol. 1992 Jul-Aug;28A(7-8):521-8.
    1522045
  • Connolly SE, Hores TA, Smith LE, D'Amore PA.Characterization of vascular development in the mouse retina.Microvasc Res. 1988 Nov;36(3):275-90.
    2466191
  • Risau W, Sweet E, D'Amore PA.Preferential expression of a 130,000-Da cell surface protein by vascular wall cells in vitro and in vivo.Microvasc Res. 1988 May;35(3):265-77.
    3292878
  • Orlidge A, D'Amore PA.Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells.J Cell Biol. 1987 Sep;105(3):1455-62.
    3654761