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William U. Shipley, MD
Publications
- Nguyen PL, Chen RC, Hoffman KE, Trofimov A, Efstathiou JA, Coen JJ, Shipley WU, Zietman AL, Talcott JA.Rectal Dose-Volume Histogram Parameters Are Associated with Long-Term Patient-Reported Gastrointestinal Quality of Life After Conventional and High-Dose
20207497 - Zhang M, Coen JJ, Suzuki Y, Siedow MR, Niemierko A, Khor LY, Pollack A, Zhang Y, Zietman AL, Shipley WU, Chakravarti A.Survivin Is a Potential Mediator of Prostate Cancer Metastasis.Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1095-103.
20231071 - Coen JJ, Bae K, Zietman AL, Patel B, Shipley WU, Slater JD, Rossi CJ.Acute and Late Toxicity After Dose Escalation to 82 GyE Using Conformal Proton Radiation for Localized Prostate Cancer: Initial Report of American College of Radiology Phase II Study 03-
20932675 - Talcott JA, Rossi C, Shipley WU, Clark JA, Slater JD, Niemierko A, Zietman AL.Patient-reported long-term outcomes after conventional and high-dose combined proton and photon radiation for early prostate cancer.JAMA. 2010 Mar 17;303(11):1046-53.
20233822 - Efstathiou JA, Shipley WU, Zietman AL, Smith MR.Hormonal therapies: ADT for prostate cancer: true love or heartbreak?.Nat Rev Clin Oncol. 2010 Mar;7(3):130-2.
20190794 - Zietman AL, Bae K, Slater JD, Shipley WU, Efstathiou JA, Coen JJ, Bush DA, Lunt M, Spiegel DY, Skowronski R, Jabola BR, Rossi CJ.Randomized trial comparing conventional-dose with high-dose conformal radiation therapy in early-stage adenocarcinoma of the p
20124169 - Viswanathan AN, Yorke ED, Marks LB, Eifel PJ, Shipley WU.Radiation dose-volume effects of the urinary bladder.Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S116-22. Review.
20171505 - Pollack A, Bae K, Khor LY, Al-Saleem T, Hammond ME, Venkatesan V, Byhardt RW, Asbell SO, Shipley WU, Sandler HM.The importance of protein kinase A in prostate cancer: relationship to patient outcome in Radiation Therapy Oncology Group trial 92-02.Clin Can
19706804 - Efstathiou JA, Bae K, Shipley WU, Kaufman DS, Hagan MP, Heney NM, Sandler HM.Late pelvic toxicity after bladder-sparing therapy in patients with invasive bladder cancer: RTOG 89-03, 95-06, 97-06, 99-06.J Clin Oncol. 2009 Sep 1;27(25):4055-61.
19636019 - Kaufman DS, Shipley WU, Feldman AS.Bladder cancer.Lancet. 2009 Jul 18;374(9685):239-49. Review.
19520422 - Wo JY,Shipley WU,Dahl DM,Coen JJ,Heney NM,Kaufman DS,Zietman AL.The results of concurrent chemo-radiotherapy for recurrence after treatment with bacillus Calmette-Guerin for non-muscle-invasive bladder cancer: is immediate cystectomy always necessary?.BJU
19154448 - Ross RW, Zietman AL, Xie W, Coen JJ, Dahl DM, Shipley WU, Kaufman DS, Islam T, Guimaraes AR, Weissleder R, Harisinghani M.Lymphotropic nanoparticle-enhanced magnetic resonance imaging (LNMRI) identifies occult lymph node metastases in prostate cancer pati
19559353 - Heney NM,Kaufman DS,Shipley WU.Surgery: selective bladder-preserving therapy for muscle-invasive cancer.Nat Rev Clin Oncol. 2009 Apr;6(4):193-4. Review.
19333224 - Ray ME,Bae K,Hussain MH,Hanks GE,Shipley WU,Sandler HM.Potential surrogate endpoints for prostate cancer survival: analysis of a phase III randomized trial.Journal of the National Cancer Institute. 2009 Feb 18;101(4):228-36.
19211454 - Montie JE,Clark PE,Eisenberger MA,El-Galley R,Greenberg RE,Herr HW,Hudes GR,Kuban DA,Kuzel TM,Lange PH,Lele SM,Michalski J,Patterson A,Pohar KS,Richie JP,Sexton WJ,Shipley WU,Small EJ,Trump DL,Walther PJ,Wilson TG.Bladder cancer.J Natl Compr Canc Netw. 20
19176203 - Kaufman DS,Winter KA,Shipley WU,Heney NM,Wallace HJ 3rd,Toonkel LM,Zietman AL,Tanguay S,Sandler HM.Phase I-II RTOG study (99-06) of patients with muscle-invasive bladder cancer undergoing transurethral surgery, paclitaxel, cisplatin, and twice-daily radio
19100600 - Efstathiou JA,Bae K,Shipley WU,Hanks GE,Pilepich MV,Sandler HM,Smith MR.Cardiovascular mortality after androgen deprivation therapy for locally advanced prostate cancer: RTOG 85-31.J Clin Oncol. 2009 Jan 1;27(1):92-9.
19047297 - Mak RH,Zietman AL,Heney NM,Kaufman DS,Shipley WU.Bladder preservation: optimizing radiotherapy and integrated treatment strategies.BJU Int. 2008 Nov;102(9 Pt B):1345-53. Review.
19035903 - Taussky D, Bae K, Bahary JP, Roach M 3rd, Lawton CA, Shipley WU, Sandler HM.Does Timing of Androgen Deprivation Influence Radiation-Induced Toxicity? A Secondary Analysis of Radiation Therapy Oncology Group Protocol 9413.Urology. 2008 Nov;72(5):1125-9.
18314175 - Zhang M,Ho A,Hammond EH,Suzuki Y,Bermudez RS,Lee RJ,Pilepich M,Shipley WU,Sandler H,Khor LY,Pollack A,Chakravarti A.Prognostic value of survivin in locally advanced prostate cancer: study based on RTOG 8610.Int J Radiat Oncol Biol Phys. 2009 Mar 15;73(4):
18977097 - Smith MR,Bae K,Efstathiou JA,Hanks GE,Pilepich MV,Sandler HM,Shipley WU.Diabetes and mortality in men with locally advanced prostate cancer: RTOG 92-02.J Clin Oncol. 2008 Sep 10;26(26):4333-9.
18779620 - Efstathiou JA, Bae K, Shipley WU, Hanks GE, Pilepich MV, Sandler HM, Smith MR.Cardiovascular Mortality and Duration of Androgen Deprivation for Locally Advanced Prostate Cancer: Analysis of RTOG 92-02.Eur Urol. 2008 Oct;54(4):816-23.
18243498 - Horwitz EM, Bae K, Hanks GE, Porter A, Grignon DJ, Brereton HD, Venkatesan V, Lawton CA, Rosenthal SA, Sandler HM, Shipley WU.Ten-Year Follow-Up of Radiation Therapy Oncology Group Protocol 92-02: A Phase III Trial of the Duration of Elective Androgen Dep
18413638 - Curran WJ Jr,Machtay M,Wasserman T,Shipley WU.Celebrating 40 years of clinical inquiry: The RTOG'S ruby anniversary.Int J Radiat Oncol Biol Phys. 2008 Jun 1;71(2):321-3.
18474307 - Efstathiou JA, Bae K, Shipley WU, Hanks GE, Pilepich MV, Sandler HM, Smith MR.Obesity and mortality in men with locally advanced prostate cancer: analysis of RTOG 85-31.Cancer. 2007 Dec 15;110(12):2691-9.
17999404 - Khor LY, Bae K, Pollack A, Hammond ME, Grignon DJ, Venkatesan VM, Rosenthal SA, Ritter MA, Sandler HM, Hanks GE, Shipley WU, Dicker AP.COX-2 expression predicts prostate-cancer outcome: analysis of data from the RTOG 92-02 trial.Lancet Oncol. 2007 Oct;8(1
17881290 - Lawton CA, Bae K, Pilepich M, Hanks G, Shipley W.Long-term treatment sequelae after external beam irradiation with or without hormonal manipulation for adenocarcinoma of the prostate: analysis of radiation therapy oncology group studies 85-31, 86-10, and
17881145 - Chakravarti A, DeSilvio M, Zhang M, Grignon D, Rosenthal S, Asbell SO, Hanks G, Sandler HM, Khor LY, Pollack A, Shipley W.Prognostic value of p16 in locally advanced prostate cancer: a study based on Radiation Therapy Oncology Group Protocol 9202.J Clin O
17634487 - Khor LY, Moughan J, Al-Saleem T, Hammond EH, Venkatesan V, Rosenthal SA, Ritter MA, Sandler HM, Hanks GE, Shipley WU, Pollack A.Bcl-2 and Bax expression predict prostate cancer outcome in men treated with androgen deprivation and radiotherapy on radiation
17575222 - Trofimov A, Nguyen PL, Coen JJ, Doppke KP, Schneider RJ, Adams JA, Bortfeld TR, Zietman AL, Delaney TF, Shipley WU.Radiotherapy treatment of early-stage prostate cancer with IMRT and protons: a treatment planning comparison.Int J Radiat Oncol Biol Phys. 2
17513063 - Roach M 3rd, De Silvio M, Rebbick T, Grignon D, Rotman M, Wolkov H, Fisher B, Hanks G, Shipley WU, Pollack A, Sandler H, Watkins-Bruner D.Racial differences in CYP3A4 genotype and survival among men treated on Radiation Therapy Oncology Group (RTOG) 9202:
17498886 - Valicenti RK, Desilvio M, Hanks GE, Porter A, Brereton H, Rosenthal SA, Shipley WU, Sandler HM.Posttreatment prostatic-specific antigen doubling time as a surrogate endpoint for prostate cancer-specific survival: An analysis of Radiation Therapy Oncology
16979837 - Horwitz EM, Levy LB, Thames HD, Kupelian PA, Martinez AA, Michalski JM, Pisansky TM, Sandler HM, Shipley WU, Zelefsky MJ, Zietman AL, Kuban DA.Biochemical and clinical significance of the posttreatment prostate-specific antigen bounce for prostate cancer
16944536 - Roach M, Hanks G, Thames H, Schellhammer P, Shipley WU, Sokol GH, Sandler H.Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: recommendations of the RTOG-ASTRO Phoenix Co
16798415 - Thames HD, Kuban DA, DeSilvio ML, Levy LB, Horwitz EM, Kupelian PA, Martinez AA, Michalski JM, Pisansky TM, Sandler HM, Shipley WU, Zelefsky MJ, Zietman AL.Increasing external beam dose for T1-T2 prostate cancer: effect on risk groups.Int J Radiat Oncol B
16750319 - Zietman AL, Chung CS, Coen JJ, Shipley WU.10-year outcome for men with localized prostate cancer treated with external radiation therapy: results of a cohort study.J Urol. 2004 Jan;171(1):210-4.
14665878 - Hanks GE, Pajak TF, Porter A, Grignon D, Brereton H, Venkatesan V, Horwitz EM, Lawton C, Rosenthal SA, Sandler HM, Shipley WU,.Phase III trial of long-term adjuvant androgen deprivation after neoadjuvant hormonal cytoreduction and radiotherapy in locally
14581419 - Thames H, Kuban D, Levy L, Horwitz EM, Kupelian P, Martinez A, Michalski J, Pisansky T, Sandler H, Shipley W, Zelefsky M, Zietman A.Comparison of alternative biochemical failure definitions based on clinical outcome in 4839 prostate cancer patients treate
14575823 - Kuban DA, Thames HD, Levy LB, Horwitz EM, Kupelian PA, Martinez AA, Michalski JM, Pisansky TM, Sandler HM, Shipley WU, Zelefsky MJ, Zietman AL.Long-term multi-institutional analysis of stage T1-T2 prostate cancer treated with radiotherapy in the PSA era.I
14575822 - Chakravarti A, Heydon K, Wu CL, Hammond E, Pollack A, Roach M, Wolkov H, Okunieff P, Cox J, Fontanesi J, Abrams R, Pilepich M, Shipley W,.Loss of p16 expression is of prognostic significance in locally advanced prostate cancer: an analysis from the Radiat
12947069 - Pollack A, Grignon DJ, Heydon KH, Hammond EH, Lawton CA, Mesic JB, Fu KK, Porter AT, Abrams RA, Shipley WU.Prostate cancer DNA ploidy and response to salvage hormone therapy after radiotherapy with or without short-term total androgen blockade: an analysi
12663710 - Shipley WU, Lu JD, Pilepich MV, Heydon K, Roach M, Wolkov HB, Sause WT, Rubin P, Lawton CA, Machtay M.Effect of a short course of neoadjuvant hormonal therapy on the response to subsequent androgen suppression in prostate cancer patients with relapse afte
12459350 - Roach M 3RD , Lu J, Pilepich MV, Asbell SO, Mohiuddin M, Terry R, Grignon D, Lawton C, Shipley W, Cox J, Mohuidden M.Predicting long-term survival, and the need for hormonal therapy: a meta-analysis of RTOG prostate cancer trials.Int J Radiat Oncol Biol P
10837944 - Chakravatri A, Zehr EM, Zietman AL, Shipley WU, Goggins WB, Finkelstein DM, Young RH, Chang EL, Wu CL.Thymosin beta-15 predicts for distant failure in patients with clinically localized prostate cancer-results from a pilot study.Urology. 2000 May;55(5):63
10792068 - Shipley WU, Kaufman DS, Heney NM, Althausen AF, Zietman AL.An update of combined modality therapy for patients with muscle invading bladder cancer using selective bladder preservation or cystectomy.J Urol. 1999 Aug;162(2):445-50; discussion 450-1.
10411054 - Shipley WU, Winter KA, Kaufman DS, Lee WR, Heney NM, Tester WR, Donnelly BJ, Venner PM, Perez CA, Murray KJ, Doggett RS, True LD.Phase III trial of neoadjuvant chemotherapy in patients with invasive bladder cancer treated with selective bladder preservati
9817278 - Zietman AL, Prince EA, Nakfoor BM, Shipley WU.Neoadjuvant androgen suppression with radiation in the management of locally advanced adenocarcinoma of the prostate: experimental and clinical results.Urology. 1997 Mar;49(3A Suppl):74-83.
9123741 - Pilepich MV, Caplan R, Byhardt RW, Lawton CA, Gallagher MJ, Mesic JB, Hanks GE, Coughlin CT, Porter A, Shipley WU, Grignon D.Phase III trial of androgen suppression using goserelin in unfavorable-prognosis carcinoma of the prostate treated with definitive
9060541 - Grignon DJ, Caplan R, Sarkar FH, Lawton CA, Hammond EH, Pilepich MV, Forman JD, Mesic J, Fu KK, Abrams RA, Pajak TF, Shipley WU, Cox JD.p53 status and prognosis of locally advanced prostatic adenocarcinoma: a study based on RTOG 8610.J Natl Cancer Inst. 1
8998185 - Hartford AC, Niemierko A, Adams JA, Urie MM, Shipley WU.Conformal irradiation of the prostate: estimating long-term rectal bleeding risk using dose-volume histograms.Int J Radiat Oncol Biol Phys. 1996 Oct 1;36(3):721-30.
8948358 - Zietman AL, Tibbs MK, Dallow KC, Smith CT, Althausen AF, Zlotecki RA, Shipley WU.Use of PSA nadir to predict subsequent biochemical outcome following external beam radiation therapy for T1-2 adenocarcinoma of the prostate.Radiother Oncol. 1996 Aug;40(2):1
8884970 - Shipley WU.PSA following irradiation for prostate cancer: the upcoming ASTRO symposium.Int J Radiat Oncol Biol Phys. 1996 Jul 15;35(5):1115.
8751422 - Shipley WU, Verhey LJ, Munzenrider JE, Suit HD, Urie MM, McManus PL, Young RH, Shipley JW, Zietman AL, Biggs PJ.Advanced prostate cancer: the results of a randomized comparative trial of high dose irradiation boosting with conformal protons compared with
7721636 - Kaufman DS, Shipley WU, Griffin PP, Heney NM, Althausen AF, Efird JT.Selective bladder preservation by combination treatment of invasive bladder cancer.N Engl J Med. 1993 Nov 4;329(19):1377-82.
8413433 - Benk VA, Adams JA, Shipley WU, Urie MM, McManus PL, Efird JT, Willett CG, Goitein M.Late rectal bleeding following combined X-ray and proton high dose irradiation for patients with stages T3-T4 prostate carcinoma.Int J Radiat Oncol Biol Phys. 1993 Jun 15;
8514551 - Shipley WU, Prout GR, Coachman NM, McManus PL, Healey EA, Althausen AF, Heney NM, Parkhurst EC, Young HH, Shipley JW.Radiation therapy for localized prostate carcinoma: experience at the Massachusetts General Hospital (1973-1981).NCI Monogr. 1988(7):67-73
3173505 - Shipley WU, Prout GR, Einstein AB, Coombs LJ, Wajsman Z, Soloway MS, Englander L, Barton BA, Hafermann MD.Treatment of invasive bladder cancer by cisplatin and radiation in patients unsuited for surgery.JAMA. 1987 Aug 21;258(7):931-5.
3613023 - Shipley WU, Bagshaw MA, Prout GR.The success of radiation therapy in controlling prostatic cancer within the treated field.Prog Clin Biol Res. 1987;243B:199-212.
3659020 - Shipley WU, Tepper JE, Prout GR, Verhey LJ, Mendiondo OA, Goitein M, Koehler AM, Suit HD.Proton radiation as boost therapy for localized prostatic carcinoma.JAMA. 1979 May 4;241(18):1912-5.
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