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Leonard I. Zon, MD

Publications

  • Svoboda O, Stachura DL, Machoňová O, Pajer P, Brynda J, Zon LI, Traver D, Bartůněk P.Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin.Blood. 2014 May 28.
    24869937
  • Kong Y, Grimaldi M, Curtin E, Dougherty M, Kaufman C, White RM, Zon LI, Liao EC.Neural crest development and craniofacial morphogenesis is coordinated by nitric oxide and histone acetylation.Chem Biol. 2014 Apr 24;21(4):488-501.
    24684905
  • Zhang X, Ling J, Barcia G, Jing L, Wu J, Barry BJ, Mochida GH, Hill RS, Weimer JM, Stein Q, Poduri A, Partlow JN, Ville D, Dulac O, Yu TW, Lam AT, Servattalab S, Rodriguez J, Boddaert N, Munnich A, Colleaux L, Zon LI, Söll D, Walsh CA, Nabbout R.Mutations in QARS, Encoding Glutaminyl-tRNA Synthetase, Cause Progressive Microcephaly, Cerebral-Cerebellar Atrophy, and Intractable Seizures.Am J Hum Genet. 2014 Apr 3;94(4):547-58.
    24656866
  • Alcaraz-Pérez F, García-Castillo J, García-Moreno D, López-Muñoz A, Anchelin M, Angosto D, Zon LI, Mulero V, Cayuela ML.A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish.Nat Commun. 2014;5:3228.
    24496182
  • Stachura DL, Svoboda O, Campbell CA, Espín-Palazón R, Lau RP, Zon LI, Bartunek P, Traver D.The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance.Blood. 2013 Dec 5;122(24):3918-28.
    24128862
  • Chen CH, Durand E, Wang J, Zon LI, Poss KD.zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish.Development. 2013 Dec;140(24):4988-97.
    24198277
  • Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI.A network of epigenetic regulators guides developmental haematopoiesis in vivo.Nat Cell Biol. 2013 Dec;15(12):1516-25.
    24240475
  • Huang H-T, Kathrein KL, Barton A, Gitlin Z, Huang Y-H, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, and Zon LI.A network of epigenetic regulators guide developmental hematopoiesis in vivo.Nat Cell Biol..
  • Paik EJ, Mahony S, White RM, Price EN, Dibiase A, Dorjsuren B, Mosimann C, Davidson AJ, Gifford D, Zon LI.A cdx4-sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis.Stem Cell Reports. 2013;1(5):425-36.
    24286030
  • Ablain J, Zon LI.Of fish and men: using zebrafish to fight human diseases.Trends Cell Biol. 2013 Dec;23(12):584-6.
    24275383
  • Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI.A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species.Cell. 2013 Nov 7;155(4):909-21.
    24209627
  • Xu C, Tabebordbar M, Lovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Kahn RC, Wagers AJ, and Zon LI.A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species.Cell..
  • Boatman S, Barrett F, Satishchandran S, Jing L, Shestopalov I, Zon LI.Assaying hematopoiesis using zebrafish.Blood Cells Mol Dis. 2013 Dec;51(4):271-6.
    23916372
  • Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, Isom M, Kao G, Armant M, Silberstein L, Hu P, Soiffer RJ, Scadden DT, Ritz J, Goessling W, North TE, Mendlein J, Ballen K, Zon LI, Antin JH, Shoemaker DD.Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation.Blood. 2013 Oct 24;122(17):3074-81.
    23996087
  • Doulatov S, Vo LT, Chou SS, Kim PG, Arora N, Li H, Hadland BK, Bernstein ID, Collins JJ, Zon LI, Daley GQ.Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.Cell Stem Cell. 2013 Oct 3;13(4):459-70.
    24094326
  • Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, Isom M, Kao G, Armant M, Silberstein L, Hu P, Soiffer RJ, Scadden DT, Ritz J, Goessling W, North TE, Mendlein J, Ballen K, Zon LI, Antin JH, Shoemaker DD.Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation.Blood..
  • Mosimann C, Puller AC, Lawson KL, Tschopp P, Amsterdam A, Zon LI.Site-directed zebrafish transgenesis into single landing sites with the phiC31 integrase system.Dev Dyn. 2013 Aug;242(8):949-63.
    23723152
  • Storer NY, White RM, Uong A, Price E, Nielsen GP, Langenau DM, Zon LI.Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis.Development. 2013 Jul;140(14):3040-50.
    23821038
  • Le X, Pugach EK, Hettmer S, Storer NY, Liu J, Wills AA, Dibiase A, Chen EY, Ignatius MS, Poss KD, Wagers AJ, Langenau DM, Zon LI.A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development.Development. 2013 Apr 24.
    23615277
  • Howe K, Clark MD, Torroja CF, Torrance J, Berthelot C, Muffato M, Collins JE, Humphray S, McLaren K, Matthews L, McLaren S, Sealy I, Caccamo M, Churcher C, Scott C, Barrett JC, Koch R, Rauch GJ, White S, Chow W, Kilian B, Quintais LT, Guerra-Assunção JA, Zhou Y, Gu Y, Yen J, Vogel JH, Eyre T, Redmond S, Banerjee R, Chi J, Fu B, Langley E, Maguire SF, Laird GK, Lloyd D, Kenyon E, Donaldson S, Sehra H, Almeida-King J, Loveland J, Trevanion S, Jones M, Quail M, Willey D, Hunt A, Burton J, Sims S, McLay K, Plumb B, Davis J, Clee C, Oliver K, Clark R, Riddle C, Eliott D, Threadgold G, Harden G, Ware D, Mortimer B, Kerry G, Heath P, Phillimore B, Tracey A, Corby N, Dunn M, Johnson C, Wood J, Clark S, Pelan S, Griffiths G, Smith M, Glithero R, Howden P, Barker N, Stevens C, Harley J, Holt K, Panagiotidis G, Lovell J, Beasley H, Henderson C, Gordon D, Auger K, Wright D, Collins J, Raisen C, Dyer L, Leung K, Robertson L, Ambridge K, Leongamornlert D, McGuire S, Gilderthorp R, Griffiths C, Manthravadi D, Nichol S, Barker G, Whitehead S, Kay M, Brown J, Murnane C, Gray E, Humphries M, Sycamore N, Barker D, Saunders D, Wallis J, Babbage A, Hammond S, Mashreghi-Mohammadi M, Barr L, Martin S, Wray P, Ellington A, Matthews N, Ellwood M, Woodmansey R, Clark G, Cooper J, Tromans A, Grafham D, Skuce C, Pandian R, Andrews R, Harrison E, Kimberley A, Garnett J, Fosker N, Hall R, Garner P, Kelly D, Bird C, Palmer S, Gehring I, Berger A, Dooley CM, Ersan-Ürün Z, Eser C, Geiger H, Geisler M, Karotki L, Kirn A, Konantz J, Konantz M, Oberländer M, Rudolph-Geiger S, Teucke M, Osoegawa K, Zhu B, Rapp A, Widaa S, Langford C, Yang F, Carter NP, Harrow J, Ning Z, Herrero J, Searle SM, Enright A, Geisler R, Plasterk RH, Lee C, Westerfield M, de Jong PJ, Zon LI, Postlethwait JH, Nüsslein-Volhard C, Hubbard TJ, Crollius HR, Rogers J, Stemple DL.The zebrafish reference genome sequence and its relationship to the human genome.Nature. 2013 Apr 17.
    23594743
  • Ciarlo CA, Zon LI.A Model for Primary Melanoma of the CNS Implicates NRAS.Cancer Discovery. 2013 Apr;3(4):382-3.
    23580282
  • Bowman TV, Zon LI.Ageing: Stem cells on a stress-busting diet.Nature. 2013 Feb 21;494(7437):317-8.
    23389448
  • Jing CB, Chen Y, Dong M, Peng XL, Jia XE, Gao L, Ma K, Deng M, Liu TX, Zon LI, Zhu J, Zhou Y, Zhou Y.Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish.Dev Biol. 2013 Feb 1;374(1):24-31.
    23220656
  • Kim PG, Albacker CE, Lu YF, Jang IH, Lim Y, Heffner GC, Arora N, Bowman TV, Lin MI, Lensch MW, De Los Angeles A, Zon LI, Loewer S, Daley GQ.Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition.Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):E141-50.
    23236128
  • Bai X, Trowbridge JJ, Riley E, Lee JA, Dibiase A, Kaartinen VM, Orkin SH, Zon LI.Tif1-Gamma Plays An Essential Role In Murine Hematopoiesis And Reguates Transcriptional Elongation Of Erythroid Genes.Dev Biol. 2012 Nov 15.
    23159334
  • McKinney-Freeman S, Cahan P, Li H, Lacadie SA, Huang HT, Curran M, Loewer S, Naveiras O, Kathrein KL, Konantz M, Langdon EM, Lengerke C, Zon LI, Collins JJ, Daley GQ.The transcriptional landscape of hematopoietic stem cell ontogeny.Cell Stem Cell. 2012 Nov 2;11(5):701-14.
    23122293
  • Oubaha M, Lin MI, Margaron Y, Filion D, Price EN, Zon LI, Côté JF, Gratton JP.Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting.Blood. 2012 Oct 18;120(16):3371-81.
    22936663
  • Jing L, Durand EM, Ezzio C, Pagliuca SM, Zon LI.In situ hybridization assay-based small molecule screening in zebrafish.Curr Protoc Chem Biol. 2012 Jun 1;4(2).
    23001521
  • Cooney JD, Hildick-Smith GJ, Shafizadeh E, McBride PF, Carroll KJ, Anderson H, Shaw GC, Tamplin OJ, Branco DS, Dalton AJ, Shah DI, Wong C, Gallagher PG, Zon LI, North TE, Paw BH.Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis.Dev Biol. 2012 Aug 29.
    22960038
  • Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, Neiswender J, Khorasani AJ, Fang R, Lezcano C, Duncan LM, Scolyer RA, Thompson JF, Kakavand H, Houvras Y, Zon LI, Mihm MC, Kaiser UB, Schatton T, Woda BA, Murphy GF, Shi YG.Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.Cell. 2012 Sep 14;150(6):1135-46.
    22980977
  • Gupta VA, Kawahara G, Myers JA, Chen AT, Hall TE, Manzini MC, Currie PD, Zhou Y, Zon LI, Kunkel LM, Beggs AH.A splice site mutation in laminin-α2 results in a severe muscular dystrophy and growth abnormalities in zebrafish.PLoS ONE. 2012;7(8):e43794.
    22952766
  • Sorrells S, Carbonneau S, Harrington E, Chen AT, Hast B, Milash B, Pyati U, Major MB, Zhou Y, Zon LI, Stewart RA, Look AT, Jette C.Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53.PLoS Genet. 2012 Aug;8(8):e1002922.
    22952453
  • Mione M, Zon LI.Cancer and inflammation: an aspirin a day keeps the cancer at bay.Curr Biol. 2012 Jul 10;22(13):R522-5.
    22789999
  • de Jong JL, Zon LI.Histocompatibility and hematopoietic transplantation in the zebrafish.Adv Hematol. 2012;2012:282318.
    22778744
  • Santoriello C, Zon LI.Hooked! Modeling human disease in zebrafish.J Clin Invest. 2012 Jul 2;122(7):2337-43.
    22751109
  • Zon LI.A great match.Cell Stem Cell. 2012 Jun 14;10(6):638-9.
    22704496
  • Taylor AM, Zon LI.Modeling diamond blackfan anemia in the zebrafish.Semin Hematol. 2011 Apr;48(2):81-8.
    21435504
  • Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferré F, Bourque C, Burke CJ, Turner L, Uong A, Johnson LA, Beroukhim R, Mermel CH, Loda M, Ait-Si-Ali S, Garraway LA, Young RA, Zon LI.The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset.Nature. 2011 Mar 24;471(7339):513-7.
    21430779
  • White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, Granter S, Young RA, Morrison S, Wheeler GN, Zon LI.DHODH modulates transcriptional elongation in the neural crest and melanoma.Nature. 2011 Mar 24;471(7339):518-22.
    21430780
  • Stachura DL, Svoboda O, Lau RP, Balla KM, Zon LI, Bartunek P, Traver D.Clonal analysis of hematopoietic progenitor cells in the zebrafish.Blood. 2011 Mar 17.
    21415264
  • de Jong JL, Burns CE, Chen AT, Pugach E, Mayhall EA, Smith AC, Feldman HA, Zhou Y, Zon LI.Characterization of immune-matched hematopoietic transplantation in zebrafish.Blood. 2011 Feb 23.
    21346254
  • Gupta V, Kawahara G, Gundry SR, Chen AT, Lencer WI, Zhou Y, Zon LI, Kunkel LM, Beggs AH.The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies.Hum Mol Genet. 2011 Feb 22.
    21296866
  • Alexander MS, Kawahara G, Kho AT, Howell MH, Pusack TJ, Myers JA, Montanaro F, Zon LI, Guyon JR, Kunkel LM.Isolation and transcriptome analysis of adult zebrafish cells enriched for skeletal muscle progenitors.Muscle Nerve. 2011 Feb 17.
    21337346
  • Bolli N, Payne EM, Rhodes J, Gjini E, Johnston AB, Guo F, Lee JS, Stewart RA, Kanki JP, Chen AT, Zhou Y, Zon LI, Look AT.cpsf1 is required for definitive hematopoietic stem cell survival in zebrafish.Blood. 2011 Feb 17.
    21330472
  • Lacadie SA, Zon LI.The ERGonomics of hematopoietic stem cell self-renewal.Genes Dev. 2011 Feb 15;25(4):289-93.
    21325129
  • Mosimann C, Kaufman CK, Li P, Pugach EK, Tamplin OJ, Zon LI.Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish.Development. 2011 Jan;138(1):169-77.
    21138979
  • Durand EM, Zon LI.Stem cells: The blood balance.Nature. 2010 Dec 2;468(7324):644-5.
    21124447
  • Feng H, Stachura DL, White RM, Gutierrez A, Zhang L, Sanda T, Jette CA, Testa JR, Neuberg DS, Langenau DM, Kutok JL, Zon LI, Traver D, Fleming MD, Kanki JP, Look AT.T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation.Cancer Cell. 2010 Oct 19;18(4):353-66.
    20951945
  • North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, Tannenbaum SR, Zon LI, Goessling W.PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury.Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17315-20.
    20855591
  • Koo S, Huntly B, Wang Y, Chen J, Brumme K, Ball B, McKinney-Freeman S, Yabuuchi A, Scholl C, Bansal D, Zon L, Froehling S, Daley G, Gilliland G, Mercher T.Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis.Haematologica. 2010 Oct;95(10):1642-50.
    20494928
  • Paik EJ, Zon LI.Hematopoietic development in the zebrafish.Int J Dev Biol. 2010;54(6-7):1127-37.
    20711990
  • Storer NY, Zon LI.Zebrafish models of p53 functions.Cold Spring Harb Perspect Biol. 2010 Aug 1;2(8):a001123.
    20679337
  • Tamplin OJ, Zon LI.Fishing at the cellular level.Nat Methods. 2010 Aug;7(8):600-1.
    20676080
  • de Jong JL, Davidson AJ, Wang Y, Palis J, Opara P, Pugach E, Daley GQ, Zon LI.Interaction of retinoic acid and scl controls primitive blood development.Blood. 2010 Jul 15;116(2):201-9.
    20410509
  • Tamplin OJ, Zon LI.Blood flow: metalloproteases cut loose in primitive erythrocytes.Curr Biol. 2010 Jul 13;20(13):R561-2.
    20619808
  • Bai X, Kim J, Yang Z, Jurynec MJ, Akie TE, Lee J, LeBlanc J, Sessa A, Jiang H, DiBiase A, Zhou Y, Grunwald DJ, Lin S, Cantor AB, Orkin SH, Zon LI.TIF1gamma controls erythroid cell fate by regulating transcription elongation.Cell. 2010 Jul 9;142(1):133-43.
    20603019
  • Durand EM, Zon LI.Newly emerging roles for prostaglandin E2 regulation of hematopoiesis and hematopoietic stem cell engraftment.Curr Opin Hematol. 2010 Jul;17(4):308-12. Review.
    20473159
  • Paik EJ, de Jong JL, Pugach E, Opara P, Zon LI.A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis.Zebrafish. 2010 Mar;7(1):61-8.
    20415644
  • Zon LI, Peterson R.The new age of chemical screening in zebrafish.Zebrafish. 2010 Mar;7(1):1.
    20415642
  • Smith AC, Raimondi AR, Salthouse CD, Ignatius MS, Blackburn JS, Mizgirev IV, Storer NY, de Jong JL, Chen AT, Zhou Y, Revskoy S, Zon LI, Langenau DM.High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.Blood. 2010 Apr 22;115(16):3296-303.
    20056790
  • Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z, Zon LI, Armstrong SA.The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.Science. 2010 Mar 26;327(5973):1650-3.
    20339075
  • Trompouki E, Zon LI.Small molecule screen in zebrafish and HSC expansion.Methods Mol Biol. 2010;636:301-16.
    20336531
  • Li P, Zon LI.Resolving the controversy about N-cadherin and hematopoietic stem cells.Cell Stem Cell. 2010 Mar 5;6(3):199-202.
    20207222
  • Bowman TV, Zon LI.Swimming into the future of drug discovery: in vivo chemical screens in zebrafish.ACS Chem Biol. 2010 Feb 19;5(2):159-61.
    20166761
  • Taylor AM, Zon LI.Zebrafish tumor assays: the state of transplantation.Zebrafish. 2009 Dec;6(4):339-46. Review.
    20047467
  • Dovey M, White RM, Zon LI.Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish.Zebrafish. 2009 Dec;6(4):397-404.
    19954345
  • Uong A, Zon LI.Melanocytes in development and cancer.J Cell Physiol. 2010 Jan;222(1):38-41. Review.
    19795394
  • Chen AT, Zon LI.Zebrafish blood stem cells.J Cell Biochem. 2009 Sep 1;108(1):35-42.
    19565566
  • Stachura DL,Reyes JR,Bartunek P,Paw BH,Zon LI,Traver D.Zebrafish kidney stromal cell lines support multilineage hematopoiesis.Blood. 2009 Jul 9;114(2):279-89.
    19433857
  • Dovey MC, Zon LI.Defining cancer stem cells by xenotransplantation in zebrafish.Methods Mol Biol. 2009;568:1-5.
    19582417
  • Dovey M,Patton EE,Bowman T,North T,Goessling W,Zhou Y,Zon LI.Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish.Mol Cell Biol. 2009 Jul;29(13):3746-53.
    19380487
  • Burns CE,Galloway JL,Smith AC,Keefe MD,Cashman TJ,Paik EJ,Mayhall EA,Amsterdam AH,Zon LI.A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence.Blood. 2009 Jun 4;113(23):5776-82.
    19332767
  • North TE,Goessling W,Peeters M,Li P,Ceol C,Lord AM,Weber GJ,Harris J,Cutting CC,Huang P,Dzierzak E,Zon LI.Hematopoietic stem cell development is dependent on blood flow.Cell. 2009 May 15;137(4):736-48.
    19450519
  • Goessling W,North TE,Loewer S,Lord AM,Lee S,Stoick-Cooper CL,Weidinger G,Puder M,Daley GQ,Moon RT,Zon LI.Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration.Cell. 2009 Mar 20;136(6):1136-47.
    19303855
  • Sessa AK,White R,Houvras Y,Burke C,Pugach E,Baker B,Gilbert R,Thomas Look A,Zon LI.The effect of a depth gradient on the mating behavior, oviposition site preference, and embryo production in the zebrafish, Danio rerio.Zebrafish. 2008 Dec;5(4):335-9.
    19133832
  • Ceol CJ,Houvras Y,White RM,Zon LI.Melanoma biology and the promise of zebrafish.Zebrafish. 2008 Dec;5(4):247-55. Review.
    19133823
  • de Jong-Curtain TA,Parslow AC,Trotter AJ,Hall NE,Verkade H,Tabone T,Christie EL,Crowhurst MO,Layton JE,Shepherd IT,Nixon SJ,Parton RG,Zon LI,Stainier DY,Lieschke GJ,Heath JK.Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish.Gastroenterology. 2009 Mar;136(3):902-11.
    19073184
  • Fraenkel PG,Gibert Y,Holzheimer JL,Lattanzi VJ,Burnett SF,Dooley KA,Wingert RA,Zon LI.Transferrin-a modulates hepcidin expression in zebrafish embryos.Blood. 2009 Mar 19;113(12):2843-50.
    19047682
  • Freeman JL,Ceol C,Feng H,Langenau DM,Belair C,Stern HM,Song A,Paw BH,Look AT,Zhou Y,Zon LI,Lee C.Construction and application of a zebrafish array comparative genomic hybridization platform.Genes Chromosomes Cancer. 2009 Feb;48(2):155-70.
    18973135
  • Imamura S,Uchiyama J,Koshimizu E,Hanai J,Raftopoulou C,Murphey RD,Bayliss PE,Imai Y,Burns CE,Masutomi K,Gagos S,Zon LI,Roberts TM,Kishi S.A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis.PLoS ONE. 2008;3(10):e3364.
    18846223
  • Flores MV,Hall CJ,Davidson AJ,Singh PP,Mahagaonkar AA,Zon LI,Crosier KE,Crosier PS.Intestinal differentiation in zebrafish requires Cdx1b, a functional equivalent of mammalian Cdx2.Gastroenterology. 2008 Nov;135(5):1665-75.
    18804112
  • Wang L,Sewell WF,Kim SD,Shin JT,MacRae CA,Zon LI,Seidman JG,Seidman CE.Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish.Development. 2008 Oct;135(20):3425-34.
    18799547
  • White RM,Zon LI.Melanocytes in development, regeneration, and cancer.Cell Stem Cell. 2008 Sep 11;3(3):242-52. Review.
    18786412
  • Trede NS,Ota T,Kawasaki H,Paw BH,Katz T,Demarest B,Hutchinson S,Zhou Y,Hersey C,Zapata A,Amemiya CT,Zon LI.Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen.Dev Dyn. 2008 Sep;237(9):2575-84.
    18729230
  • Goessling W, North TE, Lord AM, Ceol C, Lee S, Weidinger G, Bourque C, Strijbosch R, Haramis AP, Puder M, Clevers H, Moon RT, Zon LI.APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development.Dev Biol. 2008 Aug 1;320(1):161-74.
    18585699
  • Dooley KA,Fraenkel PG,Langer NB,Schmid B,Davidson AJ,Weber G,Chiang K,Foott H,Dwyer C,Wingert RA,Zhou Y,Paw BH,Zon LI.montalcino, A zebrafish model for variegate porphyria.Exp Hematol. 2008 Sep;36(9):1132-42.
    18550261
  • Zon LI.Self-renewal and differentiation at Cell Stem Cell.Cell Stem Cell. 2008 Jun 5;2(6):510.
    18522838
  • Zon LI.Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal.Nature. 2008 May 15;453(7193):306-13. Review.
    18480811
  • White RM, Sessa A, Burke C, Bowman T, LeBlanc J, Ceol C, Bourque C, Dovey M, Goessling W, Burns CE, Zon LI.Transparent adult zebrafish as a tool for in vivo transplantation analysis.Cell Stem Cell. 2008 Feb 7;2(2):183-9.
    18371439
  • Lengerke C, Schmitt S, Bowman TV, Jang IH, Maouche-Chretien L, McKinney-Freeman S, Davidson AJ, Hammerschmidt M, Rentzsch F, Green JB, Zon LI, Daley GQ.BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway.Cell Stem Cell. 2008 Jan 10;2(1):72-82.
    18371423
  • Lensch MW, Schlaeger TM, Zon LI, Daley GQ.Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera.Cell Stem Cell. 2007 Sep 13;1(3):253-8.
    18371359
  • Zon LI.Cell stem cell.Cell Stem Cell. 2007 Jun 7;1(1):7.
    18371324
  • Deutsch EW, Ball CA, Berman JJ, Bova GS, Brazma A, Bumgarner RE, Campbell D, Causton HC, Christiansen JH, Daian F, Dauga D, Davidson DR, Gimenez G, Goo YA, Grimmond S, Henrich T, Herrmann BG, Johnson MH, Korb M, Mills JC, Oudes AJ, Parkinson HE, Pascal LE, Pollet N, Quackenbush J, Ramialison M, Ringwald M, Salgado D, Sansone SA, Sherlock G, Stoeckert CJ Jr, Swedlow J, Taylor RC, Walashek L, Warford A, Wilkinson DG, Zhou Y, Zon LI, Liu AY, True LD.Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE).Nat Biotechnol. 2008 Mar;26(3):305-12.
    18327244
  • Orkin SH, Zon LI.SnapShot: hematopoiesis.Cell. 2008 Feb 22;132(4):712.
    18295585
  • Orkin SH, Zon LI.Hematopoiesis: an evolving paradigm for stem cell biology.Cell. 2008 Feb 22;132(4):631-44.
    18295580
  • Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI.Combinatorial regulation of novel erythroid gene expression in zebrafish.Exp Hematol. 2008 Apr;36(4):424-32.
    18243489
  • Lord AM, North TE, Zon LI.Prostaglandin E2: making more of your marrow.Cell Cycle. 2007 Dec;6(24):3054-7. Review.
    18075310
  • Ceol CJ, Pellman D, Zon LI.APC and colon cancer: two hits for one.Nat Med. 2007 Nov;13(11):1286-7.
    17987022
  • Burket CT, Montgomery JE, Thummel R, Kassen SC, LaFave MC, Langenau DM, Zon LI, Hyde DR.Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters.Transgenic Res. 2008 Apr;17(2):265-79.
    17968670
  • Bahary N, Goishi K, Stuckenholz C, Weber G, Leblanc J, Schafer CA, Berman SS, Klagsbrun M, Zon LI.Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish.Blood. 2007 Nov 15;110(10):3627-36.
    17698971
  • North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI.Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis.Nature. 2007 Jun 21;447(7147):1007-11.
    17581586
  • Paffett-Lugassy N, Hsia N, Fraenkel PG, Paw B, Leshinsky I, Barut B, Bahary N, Caro J, Handin R, Zon LI.Functional conservation of erythropoietin signaling in zebrafish.Blood. 2007 Oct 1;110(7):2718-26.
    17579187
  • Pfaff KL, Straub CT, Chiang K, Bear DM, Zhou Y, Zon LI.The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization.Mol Cell Biol. 2007 Aug;27(16):5887-97.
    17576815
  • Goessling W, North TE, Zon LI.Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors.Nat Methods. 2007 Jul;4(7):551-3.
    17572681
  • Goessling W, North TE, Zon LI.New waves of discovery: modeling cancer in zebrafish.J Clin Oncol. 2007 Jun 10;25(17):2473-9. Review.
    17557959
  • Le X, Langenau DM, Keefe MD, Kutok JL, Neuberg DS, Zon LI.Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish.Proc Natl Acad Sci U S A. 2007 May 29;104(22):9410-5.
    17517602
  • Langenau DM, Keefe MD, Storer NY, Guyon JR, Kutok JL, Le X, Goessling W, Neuberg DS, Kunkel LM, Zon LI.Effects of RAS on the genesis of embryonal rhabdomyosarcoma.Genes Dev. 2007 Jun 1;21(11):1382-1395.
    17510286
  • Trede NS, Medenbach J, Damianov A, Hung LH, Weber GJ, Paw BH, Zhou Y, Hersey C, Zapata A, Keefe M, Barut BA, Stuart AB, Katz T, Amemiya CT, Zon LI, Bindereif A.Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110.Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6608-13.
    17416673
  • Steffen LS, Guyon JR, Vogel ED, Beltre R, Pusack TJ, Zhou Y, Zon LI, Kunkel LM.Zebrafish orthologs of human muscular dystrophy genes.BMC Genomics. 2007;8:79.
    17374169
  • Hultman KA, Bahary N, Zon LI, Johnson SL.Gene Duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a.PLoS Genet. 2007 Jan 26;3(1):e17.
    17257055
  • Shepard JL, Amatruda JF, Finkelstein D, Ziai J, Finley KR, Stern HM, Chiang K, Hersey C, Barut B, Freeman JL, Lee C, Glickman JN, Kutok JL, Aster JC, Zon LI.A mutation in separase causes genome instability and increased susceptibility to epithelial cancer.Genes Dev. 2007 Jan 1;21(1):55-9.
    17210788
  • Murphey RD, Stern HM, Straub CT, Zon LI.A chemical genetic screen for cell cycle inhibitors in zebrafish embryos.Chem Biol Drug Des. 2006 Oct;68(4):213-9.
    17105485
  • Bansal D, Scholl C, Frhling S, McDowell E, Lee BH, Dhner K, Ernst P, Davidson AJ, Daley GQ, Zon LI, Gilliland DG, Huntly BJ.Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model.Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16924-9.
    17068127
  • Hu G, Tang J, Zhang B, Lin Y, Hanai J, Galloway J, Bedell V, Bahary N, Han Z, Ramchandran R, Thisse B, Thisse C, Zon LI, Sukhatme VP.A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro.J Cell Sci. 2006 Oct 1;119(Pt 19):4117-26.
    16968741
  • Murphey RD, Zon LI.Small molecule screening in the zebrafish.Methods. 2006 Jul;39(3):255-61.
    16877005
  • Gupta S, Zhu H, Zon LI, Evans T.BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis.Development. 2006 Jun;133(11):2177-87.
    16672337
  • Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, Brownlie A, Balzan R, Weiss MJ, Peters LL, Kaplan J, Zon LI, Paw BH.Mitoferrin is essential for erythroid iron assimilation.Nature. 2006 Mar 2;440(7080):96-100.
    16511496
  • Davidson AJ, Zon LI.The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis.Dev Biol. 2006 Apr 15;292(2):506-18.
    16457800
  • Stern HM, Murphey RD, Shepard JL, Amatruda JF, Straub CT, Pfaff KL, Weber G, Tallarico JA, King RW, Zon LI.Small molecules that delay S phase suppress a zebrafish bmyb mutant.Nat Chem Biol. 2005 Dec;1(7):366-70.
    16372403
  • Tang J, Hu G, Hanai J, Yadlapalli G, Lin Y, Zhang B, Galloway J, Bahary N, Sinha S, Thisse B, Thisse C, Jin JP, Zon LI, Sukhatme VP.A critical role for calponin 2 in vascular development.J Biol Chem. 2006 Mar 10;281(10):6664-72.
    16317011
  • de Jong JL, Zon LI.Use of the zebrafish system to study primitive and definitive hematopoiesis.Annu Rev Genet. 2005;39:481-501.
    16285869
  • MacDonald BA, Sund M, Grant MA, Pfaff KL, Holthaus K, Zon LI, Kalluri R.Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome.Blood. 2006 Mar 1;107(5):1908-15.
    16254142
  • Gardiner MR, Daggett DF, Zon LI, Perkins AC.Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching.Dev Dyn. 2005 Dec;234(4):992-6.
    16222715
  • Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI.Hematopoietic stem cell fate is established by the Notch-Runx pathway.Genes Dev. 2005 Oct 1;19(19):2331-42.
    16166372
  • Shepard JL, Amatruda JF, Stern HM, Subramanian A, Finkelstein D, Ziai J, Finley KR, Pfaff KL, Hersey C, Zhou Y, Barut B, Freedman M, Lee C, Spitsbergen J, Neuberg D, Weber G, Golub TR, Glickman JN, Kutok JL, Aster JC, Zon LI.A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility.Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13194-9.
    16150706
  • Lin HF, Traver D, Zhu H, Dooley K, Paw BH, Zon LI, Handin RI.Analysis of thrombocyte development in CD41-GFP transgenic zebrafish.Blood. 2005 Dec 1;106(12):3803-10.
    16099879
  • Donovan A, Lima CA, Pinkus JL, Pinkus GS, Zon LI, Robine S, Andrews NC.The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis.Cell Metab. 2005 Mar;1(3):191-200.
    16054062
  • Berghmans S, Murphey RD, Wienholds E, Neuberg D, Kutok JL, Fletcher CD, Morris JP, Liu TX, Schulte-Merker S, Kanki JP, Plasterk R, Zon LI, Look AT.tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors.Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):407-12.
    15630097
  • Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI.Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos.Dev Cell. 2005 Jan;8(1):109-16.
    15621534
  • Dooley KA, Davidson AJ, Zon LI.Zebrafish scl functions independently in hematopoietic and endothelial development.Dev Biol. 2005 Jan 15;277(2):522-36.
    15617691
  • Traver D, Winzeler A, Stern HM, Mayhall EA, Langenau DM, Kutok JL, Look AT, Zon LI.Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation.Blood. 2004 Sep 1;104(5):1298-305.
    15142873
  • Langenau DM, Ferrando AA, Traver D, Kutok JL, Hezel JP, Kanki JP, Zon LI, Look AT, Trede NS.In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish.Proc Natl Acad Sci U S A. 2004 May 11;101(19):7369-74.
    15123839
  • Hsu K, Traver D, Kutok JL, Hagen A, Liu TX, Paw BH, Rhodes J, Berman JN, Zon LI, Kanki JP, Look AT.The pu.1 promoter drives myeloid gene expression in zebrafish.Blood. 2004 Sep 1;104(5):1291-7.
    14996705
  • Davidson AJ, Ernst P, Wang Y, Dekens MP, Kingsley PD, Palis J, Korsmeyer SJ, Daley GQ, Zon LI.cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes.Nature. 2003 Sep 18;425(6955):300-6.
    13679919
  • Brownlie A, Hersey C, Oates AC, Paw BH, Falick AM, Witkowska HE, Flint J, Higgs D, Jessen J, Bahary N, Zhu H, Lin S, Zon L.Characterization of embryonic globin genes of the zebrafish.Dev Biol. 2003 Mar 1;255(1):48-61.
    12618133
  • Langenau DM, Traver D, Ferrando AA, Kutok JL, Aster JC, Kanki JP, Lin S, Prochownik E, Trede NS, Zon LI, Look AT.Myc-induced T cell leukemia in transgenic zebrafish.Science. 2003 Feb 7;299(5608):887-90.
    12574629
  • Donovan A, Brownlie A, Dorschner MO, Zhou Y, Pratt SJ, Paw BH, Phillips RB, Thisse C, Thisse B, Zon LI.The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1).Blood. 2002 Dec 15;100(13):4655-9.
    12393445
  • Lee P, Goishi K, Davidson AJ, Mannix R, Zon L, Klagsbrun M.Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish.Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10470-5.
    12142468
  • Mead PE, Deconinck AE, Huber TL, Orkin SH, Zon LI.Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins.Development. 2001 Jun;128(12):2301-8.
    11493549
  • Kieran MW, Katz S, Vail B, Zon LI, Mayer BJ.Concentration-dependent positive and negative regulation of a MAP kinase by a MAP kinase kinase.Oncogene. 1999 Nov 18;18(48):6647-57.
    10597270
  • Oates AC, Brownlie A, Pratt SJ, Irvine DV, Liao EC, Paw BH, Dorian KJ, Johnson SL, Postlethwait JH, Zon LI, Wilks AF.Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expression patterns: only jak2a is expressed during erythropoiesis.Blood. 1999 Oct 15;94(8):2622-36.
    10515866
  • Oates AC, Wollberg P, Pratt SJ, Paw BH, Johnson SL, Ho RK, Postlethwait JH, Zon LI, Wilks AF.Zebrafish stat3 is expressed in restricted tissues during embryogenesis and stat1 rescues cytokine signaling in a STAT1-deficient human cell line.Dev Dyn. 1999 Aug;215(4):352-70.
    10417824
  • Amemiya CT, Zon LI.Generation of a zebrafish P1 artificial chromosome library.Genomics. 1999 Jun 1;58(2):211-3.
    10366454
  • Huber TL, Zhou Y, Mead PE, Zon LI.Cooperative effects of growth factors involved in the induction of hematopoietic mesoderm.Blood. 1998 Dec 1;92(11):4128-37.
    9834218
  • Brownlie A, Donovan A, Pratt SJ, Paw BH, Oates AC, Brugnara C, Witkowska HE, Sassa S, Zon LI.Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia.Nat Genet. 1998 Nov;20(3):244-50.
    9806542
  • Mead PE, Zhou Y, Lustig KD, Huber TL, Kirschner MW, Zon LI.Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins.Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11251-6.
    9736722
  • Frnzler D, Her H, Knapik EW, Clark M, Lehrach H, Postlethwait JH, Zon LI, Beier DR.Gene mapping in zebrafish using single-strand conformation polymorphism analysis.Genomics. 1998 Jul 15;51(2):216-22.
    9722944
  • Alberola-Ila J, Levin SD, Barton G, Forbush K, Zon LI, Perlmutter RM.Analysis of the role of MKK-4/Sek-1 in T cell development and apoptosis.Int Immunol. 1998 Aug;10(8):1077-82.
    9723693
  • Kwok C, Korn RM, Davis ME, Burt DW, Critcher R, McCarthy L, Paw BH, Zon LI, Goodfellow PN, Schmitt K.Characterization of whole genome radiation hybrid mapping resources for non-mammalian vertebrates.Nucleic Acids Res. 1998 Aug 1;26(15):3562-6.
    9671819
  • Mead PE, Kelley CM, Hahn PS, Piedad O, Zon LI.SCL specifies hematopoietic mesoderm in Xenopus embryos.Development. 1998 Jul;125(14):2611-20.
    9636076
  • Thompson MA, Ransom DG, Pratt SJ, MacLennan H, Kieran MW, Detrich HW, Vail B, Huber TL, Paw B, Brownlie AJ, Oates AC, Fritz A, Gates MA, Amores A, Bahary N, Talbot WS, Her H, Beier DR, Postlethwait JH, Zon LI.The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis.Dev Biol. 1998 May 15;197(2):248-69.
    9630750
  • Ganiatsas S, Kwee L, Fujiwara Y, Perkins A, Ikeda T, Labow MA, Zon LI.SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis.Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6881-6.
    9618507
  • Swat W, Fujikawa K, Ganiatsas S, Yang D, Xavier RJ, Harris NL, Davidson L, Ferrini R, Davis RJ, Labow MA, Flavell RA, Zon LI, Alt FW.SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development.Immunity. 1998 May;8(5):625-34.
    9620683
  • Jessen JR, Meng A, McFarlane RJ, Paw BH, Zon LI, Smith GR, Lin S.Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis.Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5121-6.
    9560239
  • Liao EC, Paw BH, Oates AC, Pratt SJ, Postlethwait JH, Zon LI.SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish.Genes Dev. 1998 Mar 1;12(5):621-6.
    9499398
  • Orkin SH, Zon LI.Genetics of erythropoiesis: induced mutations in mice and zebrafish.Annu Rev Genet. 1997;31:33-60.
    9442889
  • Kieran MW, Zon LI.Stress- and mitogen-activated signal transduction in hematopoietic cells.Curr Opin Hematol. 1996 Jan;3(1):27-34.
    9372048
  • Turpen JB, Kelley CM, Mead PE, Zon LI.Bipotential primitive-definitive hematopoietic progenitors in the vertebrate embryo.Immunity. 1997 Sep;7(3):325-34.
    9324353
  • Chan FY, Robinson J, Brownlie A, Shivdasani RA, Donovan A, Brugnara C, Kim J, Lau BC, Witkowska HE, Zon LI.Characterization of adult alpha- and beta-globin genes in the zebrafish.Blood. 1997 Jan 15;89(2):688-700.
    9002973
  • Maeno M, Mead PE, Kelley C, Xu RH, Kung HF, Suzuki A, Ueno N, Zon LI.The role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevis.Blood. 1996 Sep 15;88(6):1965-72.
    8822915
  • Kieran MW, Perkins AC, Orkin SH, Zon LI.Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9126-31.
    8799165
  • Mead PE, Brivanlou IH, Kelley CM, Zon LI.BMP-4-responsive regulation of dorsal-ventral patterning by the homeobox protein Mix.1.Nature. 1996 Jul 25;382(6589):357-60.
    8684465
  • Sen J, Kapeller R, Fragoso R, Sen R, Zon LI, Burakoff SJ.Intrathymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase.J Immunol. 1996 Jun 15;156(12):4535-8.
    8648093
  • Detrich HW, Kieran MW, Chan FY, Barone LM, Yee K, Rundstadler JA, Pratt S, Ransom D, Zon LI.Intraembryonic hematopoietic cell migration during vertebrate development.Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10713-7.
    7479870
  • Pombo CM, Kehrl JH, Snchez I, Katz P, Avruch J, Zon LI, Woodgett JR, Force T, Kyriakis JM.Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase.Nature. 1995 Oct 26;377(6551):750-4.
    7477268
  • Stainier DY, Weinstein BM, Detrich HW, Zon LI, Fishman MC.Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages.Development. 1995 Oct;121(10):3141-50.
    7588049
  • Snchez I, Hughes RT, Mayer BJ, Yee K, Woodgett JR, Avruch J, Kyriakis JM, Zon LI.Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun.Nature. 1994 Dec 22-29;372(6508):794-8.
    7997269
  • Yan M, Dai T, Deak JC, Kyriakis JM, Zon LI, Woodgett JR, Templeton DJ.Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1.Nature. 1994 Dec 22-29;372(6508):798-800.
    7997270