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David G. Nathan, MD


  • Sankaran VG, Ghazvinian R, Do R, Thiru P, Vergilio JA, Beggs AH, Sieff CA, Orkin SH, Nathan DG, Lander ES, Gazda HT.Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia.J Clin Invest. 2012 Jul 2;122(7):2439-43.
  • Narla A, Vlachos A, Nathan DG.Diamond blackfan anemia treatment: past, present, and future.Semin Hematol. 2011 Apr;48(2):117-23.
  • Field JJ, Nathan DG, Linden J.Targeting iNKT cells for the treatment of sickle cell disease.Clin Immunol. 2011 Mar 21.
  • Sankaran VG, Nathan DG.Reversing the hemoglobin switch.N Engl J Med. 2010 Dec 2;363(23):2258-60.
  • Sankaran VG, Nathan DG.Thalassemia: an overview of 50 years of clinical research.Hematol Oncol Clin North Am. 2010 Dec;24(6):1005-20.
  • Nathan DG.A life-long quest to understand and treat genetic blood disorders.Cell. 2010 Oct 1;143(1):17-20.
  • Bunn HF, Nathan DG, Dover GJ, Hebbel RP, Platt OS, Rosse WF, Ware RE.Pulmonary hypertension and nitric oxide depletion in sickle cell disease.Blood. 2010 Aug 5;116(5):687-92. Review.
  • Nathan DG, Orkin SH.Musings on genome medicine: Hepatitis C.Genome Med. 2010 Jan 27;2(1):4.
  • Nathan DG, Orkin SH.Musings on genome medicine: Crohn's disease.Genome Med. 2009;1(11):103.
  • Nathan DG, Orkin SH.Musings on genome medicine: enzyme-replacement therapy of the lysosomal storage diseases.Genome Med. 2009;1(12):114.
  • Nathan DG, Orkin SH.Musings on genome medicine: the slow but inexorable process of medical care reform in the United States.Genome Med. 2009;1(10):94.
  • Nathan DG, Orkin SH.Musings on genome medicine: the Obama effect redux.Genome Med. 2009;1(9):86.
  • Nathan DG, Orkin SH.Musings on genome medicine: cholesterol and coronary artery disease.Genome Med. 2009;1(6):60.
  • Rebel VI, Tanaka M, Lee JS, Hartnett S, Pulsipher M, Nathan DG, Mulligan RC, Sieff CA.One-day ex vivo culture allows effective gene transfer into human nonobese diabetic/severe combined immune-deficient repopulating cells using high-titer vesicular stomatitis virus G protein pseudotyped retrovirus.Blood. 1999 Apr 1;93(7):2217-24.
  • Nathan DG, Weatherall DJ.Iron chelation with oral deferiprone in patients with thalassemia.N Engl J Med. 1998 Dec 3;339(23):1711-2; author reply 1713.
  • Janov AJ, Leong T, Nathan DG, Guinan EC.Diamond-Blackfan anemia. Natural history and sequelae of treatment.Medicine (Baltimore). 1996 Mar;75(2):77-8.
  • Olivieri NF, Nathan DG, MacMillan JH, Wayne AS, Liu PP, McGee A, Martin M, Koren G, Cohen AR.Survival in medically treated patients with homozygous beta-thalassemia.N Engl J Med. 1994 Sep 1;331(9):574-8.
  • Guinan EC, Lopez KD, Huhn RD, Felser JM, Nathan DG.Evaluation of granulocyte-macrophage colony-stimulating factor for treatment of pancytopenia in children with fanconi anemia.J Pediatr. 1994 Jan;124(1):144-50.
  • Bianchi DW, Bernfield M, Nathan DG.A revived opportunity for fetal research.Nature. 1993 May 6;363(6424):12.
  • Guinan EC, Lee YS, Lopez KD, Kohler S, Oette DH, Bruno E, Kozakewich H, Nathan DG, Hoffman R.Effects of interleukin-3 and granulocyte-macrophage colony-stimulating factor on thrombopoiesis in congenital amegakaryocytic thrombocytopenia.Blood. 1993 Apr 1;81(7):1691-8.
  • Wayne AS, Kevy SV, Nathan DG.Transfusion management of sickle cell disease.Blood. 1993 Mar 1;81(5):1109-23.
  • Davies K, TePas EC, Nathan DG, Mathey-Prevot B.Interleukin-3 expression by activated T cells involves an inducible, T-cell-specific factor and an octamer binding protein.Blood. 1993 Feb 15;81(4):928-34.
  • Jubinsky PT, Nathan DG, Wilson DJ, Sieff CA.A low-affinity human granulocyte-macrophage colony-stimulating factor/murine erythropoietin hybrid receptor functions in murine cell lines.Blood. 1993 Feb 1;81(3):587-91.
  • Sieff CA, Yokoyama CT, Zsebo KM, Trammell J, Andersen JW, Nathan DG, Williams DA.The production of steel factor mRNA in Diamond-Blackfan anaemia long-term cultures and interactions of steel factor with erythropoietin and interleukin-3.Br J Haematol. 1992 Dec;82(4):640-7.
  • McDonagh KT, Dover GJ, Donahue RE, Nathan DG, Agricola B, Byrne E, Nienhuis AW.Hydroxyurea-induced HbF production in anemic primates: augmentation by erythropoietin, hematopoietic growth factors, and sodium butyrate.Exp Hematol. 1992 Nov;20(10):1156-64.
  • Liboi E, Jubinsky P, Andrews NC, Nathan DG, Mathey-Prevot B.Enhanced expression of interleukin-3 and granulocyte-macrophage colony-stimulating factor receptor subunits in murine hematopoietic cells stimulated with hematopoietic growth factors.Blood. 1992 Sep 1;80(5):1183-9.
  • Crosier KE, Wong GG, Mathey-Prevot B, Nathan DG, Sieff CA.A functional isoform of the human granulocyte/macrophage colony-stimulating factor receptor has an unusual cytoplasmic domain.Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7744-8.