Lewis B. Silverman, MD

Publications

• Grace RF, Dahlberg SE, Neuberg D, Sallan SE, Connors JM, Neufeld EJ, Deangelo DJ, Silverman LB.The frequency and management of asparaginase-related thrombosis in paediatric and adult patients with acute lymphoblastic leukaemia treated on Dana-Farber Cance
  21210774
• Aricò M, Schrappe M, Hunger SP, Carroll WL, Conter V, Galimberti S, Manabe A, Saha V, Baruchel A, Vettenranta K, Horibe K, Benoit Y, Pieters R, Escherich G, Silverman LB, Pui CH, Valsecchi MG.Clinical Outcome of Children With Newly Diagnosed Philadelphia
  20876426
• Mann G, Attarbaschi A, Schrappe M, De Lorenzo P, Peters C, Hann I, De Rossi G, Felice M, Lausen B, Leblanc T, Szczepanski T, Ferster A, Janka-Schaub G, Rubnitz J, Silverman LB, Stary J, Campbell M, Li CK, Suppiah R, Biondi A, Vora A, Valsecchi MG, Pieters
  20592248
• Lipshultz SE, Scully RE, Lipsitz SR, Sallan SE, Silverman LB, Miller TL, Barry EV, Asselin BL, Athale U, Clavell LA, Larsen E, Moghrabi A, Samson Y, Michon B, Schorin MA, Cohen HJ, Neuberg DS, Orav EJ, Colan SD.Assessment of dexrazoxane as a cardioprotect
  20850381
• Gutierrez A, Dahlberg SE, Neuberg DS, Zhang J, Grebliunaite R, Sanda T, Protopopov A, Tosello V, Kutok J, Larson RS, Borowitz MJ, Loh ML, Ferrando AA, Winter SS, Mullighan CG, Silverman LB, Chin L, Hunger SP, Sallan SE, Look AT.Absence of biallelic TCRgam
  20644084
• Horton TM, Sposto R, Brown P, Reynolds CP, Hunger SP, Winick NJ, Raetz EA, Carroll WL, Arceci RJ, Borowitz MJ, Gaynon PS, Gore L, Jeha S, Maurer BJ, Siegel SE, Biondi A, Kearns PR, Narendran A, Silverman LB, Smith MA, Zwaan CM, Whitlock JA.Toxicity assess
  20127846
• Gutierrez A, Sanda T, Ma W, Zhang J, Grebliunaite R, Dahlberg S, Neuberg D, Protopopov A, Winter SS, Larson RS, Borowitz MJ, Silverman LB, Chin L, Hunger SP, Jamieson C, Sallan SE, Look AT.Inactivation of LEF1 in T-cell acute lymphoblastic leukemia.Blood.
  20124220
• Silverman LB, Supko JG, Stevenson KE, Woodward C, Vrooman LM, Neuberg DS, Asselin BL, Athale UH, Clavell L, Cole PD, Kelly KM, Laverdière C, Michon B, Schorin M, Schwartz CL, O'Brien JE, Cohen HJ, Sallan SE.Intravenous PEG-asparaginase during remissi
  20007809
• Vrooman LM, Supko JG, Neuberg DS, Asselin BL, Athale UH, Clavell L, Kelly KM, Laverdière C, Michon B, Schorin M, Cohen HJ, Sallan SE, Silverman LB.Erwinia asparaginase after allergy to E. coli asparaginase in children with acute lymphoblastic leukemia.Pe
  19672973
• Al-Shakfa F, Dulucq S, Brukner I, Milacic I, Ansari M, Beaulieu P, Moghrabi A, Laverdière C, Sallan SE, Silverman LB, Neuberg D, Kutok JL, Sinnett D, Krajinovic M.DNA variants in region for noncoding interfering transcript of dihydrofolate reductase gene
  19861437
• van der Linden MH, Valsecchi MG, De Lorenzo P, Möricke A, Janka G, Leblanc TM, Felice M, Biondi A, Campbell M, Hann I, Rubnitz JE, Stary J, Szczepanski T, Vora A, Ferster A, Hovi L, Silverman LB, Pieters R.Outcome of congenital acute lymphoblastic leukem
  19657114
• Sallan SE, Schrappe M, Silverman LB.Treating childhood leukemia without cranial irradiation.N Engl J Med. 2009 Sep 24;361(13):1310; author reply 1311-2.
  19776415
• Gutierrez A,Sanda T,Grebliunaite R,Carracedo A,Salmena L,Ahn Y,Dahlberg S,Neuberg D,Moreau LA,Winter SS,Larson R,Zhang J,Protopopov A,Chin L,Pandolfi PP,Silverman LB,Hunger SP,Sallan SE,Look AT.High frequency of PTEN, PI3K and AKT abnormalities in T cell
  19458356
• Kearney SL,Dahlberg SE,Levy DE,Voss SD,Sallan SE,Silverman LB.Clinical course and outcome in children with acute lymphoblastic leukemia and asparaginase-associated pancreatitis.Pediatr Blood Cancer. 2009 Aug;53(2):162-7.
  19405141
• Vrooman LM,Silverman LB.Childhood acute lymphoblastic leukemia: update on prognostic factors.Curr Opin Pediatr. 2009 Feb;21(1):1-8. Review.
  19242236
• Krivtsov AV,Feng Z,Lemieux ME,Faber J,Vempati S,Sinha AU,Xia X,Jesneck J,Bracken AP,Silverman LB,Kutok JL,Kung AL,Armstrong SA.H3K79 methylation profiles define murine and human MLL-AF4 leukemias.Cancer Cell. 2008 Nov 4;14(5):355-68.
  18977325
• Barry EV, Vrooman LM, Dahlberg SE, Neuberg DS, Asselin BL, Athale UH, Clavell LA, Larsen EC, Moghrabi A, Samson Y, Schorin MA, Cohen HJ, Lipshultz SE, Sallan SE, Silverman LB.Absence of secondary malignant neoplasms in children with high-risk acute lympho
  18309945
• O'Neil J, Tchinda J, Gutierrez A, Moreau L, Maser RS, Wong KK, Li W, McKenna K, Liu XS, Feng B, Neuberg D, Silverman L, DeAngelo DJ, Kutok JL, Rothstein R, DePinho RA, Chin L, Lee C, Look AT.Alu elements mediate MYB gene tandem duplication in human T-
  18070937
• Waber DP, Turek J, Catania L, Stevenson K, Robaey P, Romero I, Adams H, Alyman C, Jandet-Brunet C, Neuberg DS, Sallan SE, Silverman LB.Neuropsychological outcomes from a randomized trial of triple intrathecal chemotherapy compared with 18 Gy cranial radia
  17971588
• Silverman LB.Acute lymphoblastic leukemia in infancy.Pediatr Blood Cancer. 2007 Dec;49(7 Suppl):1070-3. Review.
  17943956
• Rodig SJ, Payne EG, Degar BA, Rollins B, Feldman AL, Jaffe ES, Androkites A, Silverman LB, Longtine JA, Kutok JL, Fleming MD, Aster JC.Aggressive Langerhans cell histiocytosis following T-ALL: clonally related neoplasms with persistent expression of const
  17874453
• Zhou J, Goldwasser MA, Li A, Dahlberg SE, Neuberg D, Wang H, Dalton V, McBride KD, Sallan SE, Silverman LB, Gribben JG.Quantitative analysis of minimal residual disease predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL c
  17485550
• Nachman JB, Heerema NA, Sather H, Camitta B, Forestier E, Harrison CJ, Dastugue N, Schrappe M, Pui CH, Basso G, Silverman LB, Janka GE.Outcome of treatment in children with hypodiploid acute lymphoblastic leukemia.Blood. 2007 Aug 15;110(4):1112-5.
  17473063
• Pieters R, Schrappe M, De Lorenzo P, Hann I, De Rossi G, Felice M, Hovi L, LeBlanc T, Szczepanski T, Ferster A, Janka G, Rubnitz J, Silverman L, Stary J, Campbell M, Li CK, Mann G, Suppiah R, Biondi A, Vora A, Valsecchi MG.A treatment protocol for infants
  17658395
• Barry E, DeAngelo DJ, Neuberg D, Stevenson K, Loh ML, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin M, Cohen HJ, Sallan SE, Silverman LB.Favorable outcome for adolescents with acute lymphoblastic leukemia treated on Dana-Farbe
  17327603
• Moghrabi A, Levy DE, Asselin B, Barr R, Clavell L, Hurwitz C, Samson Y, Schorin M, Dalton VK, Lipshultz SE, Neuberg DS, Gelber RD, Cohen HJ, Sallan SE, Silverman LB.Results of the Dana-Farber Cancer Institute ALL Consortium Protocol 95-01 for children wit
  17003366
• Loh ML, Goldwasser MA, Silverman LB, Poon WM, Vattikuti S, Cardoso A, Neuberg DS, Shannon KM, Sallan SE, Gilliland DG.Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute Consortium Protocol 95-01.Blood. 2006 Jun 1;10
  16493009
• Li A, Goldwasser MA, Zhou J, Armstrong SA, Wang H, Dalton V, Fletcher JA, Sallan SE, Silverman LB, Gribben JG.Distinctive IGH gene segment usage and minimal residual disease detection in infant acute lymphoblastic leukaemias.Br J Haematol. 2005 Oct;131(2)
  16197448
• Haining WN, Neuberg DS, Keczkemethy HL, Evans JW, Rivoli S, Gelman R, Rosenblatt HM, Shearer WT, Guenaga J, Douek DC, Silverman LB, Sallan SE, Guinan EC, Nadler LM.Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leu
  15920008
• Moorman AV, Raimondi SC, Pui CH, Baruchel A, Biondi A, Carroll AJ, Forestier E, Gaynon PS, Harbott J, Harms DO, Heerema N, Pieters R, Schrappe M, Silverman LB, Vilmer E, Harrison CJ,.No prognostic effect of additional chromosomal abnormalities in children
  15744345
• Haining WN, Cardoso AA, Keczkemethy HL, Fleming M, Neuberg D, DeAngelo DJ, Stone RM, Galinsky I, Silverman LB, Sallan SE, Nadler LM, Guinan EC.Failure to define window of time for autologous tumor vaccination in patients with newly diagnosed or relapsed a
  15730852
• Weng AP, Ferrando AA, Lee W, Morris JP, Silverman LB, Sanchez-Irizarry C, Blacklow SC, Look AT, Aster JC.Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.Science. 2004 Oct 8;306(5694):269-71.
  15472075
• Lipshultz SE, Rifai N, Dalton VM, Levy DE, Silverman LB, Lipsitz SR, Colan SD, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin MA, Gelber RD, Sallan SE.The effect of dexrazoxane on myocardial injury in doxorubicin-treated childr
  15247354
• Waber DP, Silverman LB, Catania L, Mautz W, Rue M, Gelber RD, Levy DE, Goldwasser MA, Adams H, Dufresne A, Metzger V, Romero I, Tarbell NJ, Dalton VK, Sallan SE.Outcomes of a randomized trial of hyperfractionated cranial radiation therapy for treatment of
  15226337
• Li A, Rue M, Zhou J, Wang H, Goldwasser MA, Neuberg D, Dalton V, Zuckerman D, Lyons C, Silverman LB, Sallan SE, Gribben JG.Utilization of Ig Heavy-Chain Variable, Diversity and Joining Gene Segments in Children with B-lineage Acute Lymphoblastic Leukemia:
  15010366
• Armstrong SA, Mabon ME, Silverman LB, Li A, Gribben JG, Fox EA, Sallan SE, Korsmeyer SJ.FLT3 mutations in childhood acute lymphoblastic leukemia.Blood. 2004 May 1;103(9):3544-6.
  14670924
• Goldberg JM, Silverman LB, Levy DE, Dalton VK, Gelber RD, Lehmann L, Cohen HJ, Sallan SE, Asselin BL.Childhood T-cell acute lymphoblastic leukemia: the Dana-Farber Cancer Institute acute lymphoblastic leukemia consortium experience.J Clin Oncol. 2003 Oct
  14512392
• Li A, Zhou J, Zuckerman D, Rue M, Dalton V, Lyons C, Silverman LB, Sallan SE, Gribben JG.Sequence analysis of clonal immunoglobulin and T-cell receptor gene rearrangements in children with acute lymphoblastic leukemia at diagnosis and at relapse: implicat
  12946997
• Dalton VK, Rue M, Silverman LB, Gelber RD, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin M, Tarbell NJ, Sallan SE, Cohen LE.Height and weight in children treated for acute lymphoblastic leukemia: relationship to CNS treatment.
  12885815
• Silverman LB, Sallan SE.Newly diagnosed childhood acute lymphoblastic leukemia: update on prognostic factors and treatment.Curr Opin Hematol. 2003 Jul;10(4):290-6.
  12799535
• Ferrando AA, Armstrong SA, Neuberg DS, Sallan SE, Silverman LB, Korsmeyer SJ, Look AT.Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.Blood. 2003 Jul 1;102(1):262-8.
  12637319
• Armstrong SA, Kung AL, Mabon ME, Silverman LB, Stam RW, Den Boer ML, Pieters R, Kersey JH, Sallan SE, Fletcher JA, Golub TR, Griffin JD, Korsmeyer SJ.Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classif
  12620411
• LeClerc JM, Billett AL, Gelber RD, Dalton V, Tarbell N, Lipton JM, Barr R, Clavell LA, Asselin B, Hurwitz C, Schorin M, Lipshultz SE, Declerck L, Silverman LB, Cohen HJ, Sallan SE.Treatment of childhood acute lymphoblastic leukemia: results of Dana-Farber
  11773175
• Armstrong SA, Staunton JE, Silverman LB, Pieters R, den Boer ML, Minden MD, Sallan SE, Lander ES, Golub TR, Korsmeyer SJ.MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia.Nat Genet. 2002 Jan;30(1):41-7.
  11731795
• Waber DP, Shapiro BL, Carpentieri SC, Gelber RD, Zou G, Dufresne A, Romero I, Tarbell NJ, Silverman LB, Sallan SE.Excellent therapeutic efficacy and minimal late neurotoxicity in children treated with 18 grays of cranial radiation therapy for high-risk ac
  11443604
• Strauss AJ, Su JT, Dalton VM, Gelber RD, Sallan SE, Silverman LB.Bony morbidity in children treated for acute lymphoblastic leukemia.J Clin Oncol. 2001 Jun 15;19(12):3066-72.
  11408503
• Silverman LB, Gelber RD, Dalton VK, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin MA, Arkin S, Declerck L, Cohen HJ, Sallan SE.Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium
  11222362
• Silverman LB, Declerck L, Gelber RD, Dalton VK, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin MA, Lipton JM, Cohen HJ, Sallan SE.Results of Dana-Farber Cancer Institute Consortium protocols for children with newly diagnosed ac
  11187916
• Waber DP, Carpentieri SC, Klar N, Silverman LB, Schwenn M, Hurwitz CA, Mullenix PJ, Tarbell NJ, Sallan SE.Cognitive sequelae in children treated for acute lymphoblastic leukemia with dexamethasone or prednisone.J Pediatr Hematol Oncol. 2000 May-Jun;22(3):
  10864051
• Hurwitz CA, Silverman LB, Schorin MA, Clavell LA, Dalton VK, Glick KM, Gelber RD, Sallan SE.Substituting dexamethasone for prednisone complicates remission induction in children with acute lymphoblastic leukemia.Cancer. 2000 Apr 15;88(8):1964-9.
  10760775
• Silverman LB, Gelber RD, Young ML, Dalton VK, Barr RD, Sallan SE.Induction failure in acute lymphoblastic leukemia of childhood.Cancer. 1999 Mar 15;85(6):1395-404.
  10189148
• Loh ML, Silverman LB, Young ML, Neuberg D, Golub TR, Sallan SE, Gilliland DG.Incidence of TEL/AML1 fusion in children with relapsed acute lymphoblastic leukemia.Blood. 1998 Dec 15;92(12):4792-7.
  9845546
• Silverman LB, McLean TW, Gelber RD, Donnelly MJ, Gilliland DG, Tarbell NJ, Sallan SE.Intensified therapy for infants with acute lymphoblastic leukemia: results from the Dana-Farber Cancer Institute Consortium.Cancer. 1997 Dec 15;80(12):2285-95.
  9404706
• Silverman LB, Weinstein HJ.Treatment of childhood leukemia.Curr Opin Oncol. 1997 Jan;9(1):26-33.
  9090491