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Lewis B. Silverman, MD

Publications

  • Reynolds C, Roderick JE, LaBelle JL, Bird G, Mathieu R, Bodaar K, Colon D, Pyati U, Stevenson KE, Qi J, Harris M, Silverman LB, Sallan SE, Bradner JE, Neuberg DS, Look AT, Walensky LD, Kelliher MA, Gutierrez A.Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia.Leukemia. 2014 Sep(9):1819-27.
    24552990
  • Ben Tanfous M, Sharif-Askari B, Ceppi F, Laaribi H, Gagné V, Rousseau J, Labuda M, Silverman LB, Sallan SE, Neuberg D, Kutok JL, Sinnett D, Laverdière C, Krajinovic M.Polymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia.Clin Cancer Res. 2014 Jun 6.
    24907114
  • Lane AA, Chapuy B, Lin CY, Tivey T, Li H, Townsend EC, van Bodegom D, Day TA, Wu SC, Liu H, Yoda A, Alexe G, Schinzel AC, Sullivan TJ, Malinge S, Taylor JE, Stegmaier K, Jaffe JD, Bustin M, te Kronnie G, Izraeli S, Harris MH, Stevenson KE, Neuberg D, Silverman LB, Sallan SE, Bradner JE, Hahn WC, Crispino JD, Pellman D, Weinstock DM.Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.Nat Genet. 2014 Jun(6):618-23.
    24747640
  • Mar BG, Bullinger LB, McLean KM, Grauman PV, Harris MH, Stevenson K, Neuberg DS, Sinha AU, Sallan SE, Silverman LB, Kung AL, Lo Nigro L, Ebert BL, Armstrong SA.Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia.Nat Commun. 2014;5:3469.
    24662245
  • Roderick JE, Tesell J, Shultz LD, Brehm MA, Greiner DL, Harris MH, Silverman LB, Sallan SE, Gutierrez A, Look AT, Qi J, Bradner JE, Kelliher MA.c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.Blood. 2014 Feb 13;123(7):1040-50.
    24394663
  • Sanchez R, St-Cyr J, Lalonde ME, Healy J, Richer C, Gagné V, Laverdière C, Silverman LB, Sallan SE, Neuberg D, Kutok JL, Kritikou EA, Krajinovic M, Sinnett D.Impact of promoter polymorphisms in key regulators of the intrinsic apoptosis pathway on the outcome of childhood acute lymphoblastic leukemia.Haematologica. 2014 Feb;99(2):314-21.
    24038028
  • Plourde PV, Jeha S, Hijiya N, Keller FG, Silverman LB, Rheingold SR, Dreyer ZE, Dahl GV, Mercedes T, Lai C, Corn T.Safety profile of asparaginase Erwinia chrysanthemi in a large compassionate-use trial.Pediatr Blood Cancer. 2014 Jan 16.
    24436152
  • Buitenkamp TD, Izraeli S, Zimmermann M, Forestier E, Heerema NA, van den Heuvel-Eibrink MM, Pieters R, Korbijn CM, Silverman LB, Schmiegelow K, Liang DC, Horibe K, Arico M, Biondi A, Basso G, Rabin KR, Schrappe M, Cario G, Mann G, Morak M, Panzer-Grümayer R, Mondelaers V, Lammens T, Cavé H, Stark B, Ganmore I, Moorman AV, Vora A, Hunger SP, Pui CH, Mullighan CG, Manabe A, Escherich G, Kowalczyk JR, Whitlock JA, Zwaan CM.Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group.Blood. 2014 Jan 2;123(1):70-7.
    24222333
  • Lipshultz SE, Lipsitz SR, Kutok JL, Miller TL, Colan SD, Neuberg DS, Stevenson KE, Fleming MD, Sallan SE, Franco VI, Henkel JM, Asselin BL, Athale UH, Clavell LA, Michon B, Laverdiere C, Larsen E, Kelly KM, Silverman LB.Impact of hemochromatosis gene mutations on cardiac status in doxorubicin-treated survivors of childhood high-risk leukemia.Cancer. 2013 Oct 1;119(19):3555-62.
    23861158
  • Gagné V, Rousseau J, Labuda M, Sharif-Askari B, Brukner I, Laverdière C, Ceppi F, Sallan SE, Silverman LB, Neuberg D, Kutok JL, Sinnett D, Krajinovic M.Bim polymorphisms: influence on function and response to treatment in children with acute lymphoblastic leukemia.Clin Cancer Res. 2013 Sep 15;19(18):5240-9.
    23908358
  • Waber DP, McCabe M, Sebree M, Forbes PW, Adams H, Alyman C, Sands SA, Robaey P, Romero I, Routhier MÈ, Girard JM, Sallan SE, Silverman LB.Neuropsychological outcomes of a randomized trial of prednisone versus dexamethasone in acute lymphoblastic leukemia: findings from Dana-Farber Cancer Institute All Consortium Protocol 00-01.Pediatr Blood Cancer. 2013 Nov;60(11):1785-91.
    23832430
  • Vrooman LM, Stevenson KE, Supko JG, O'Brien J, Dahlberg SE, Asselin BL, Athale UH, Clavell LA, Kelly KM, Kutok JL, Laverdière C, Lipshultz SE, Michon B, Schorin M, Relling MV, Cohen HJ, Neuberg DS, Sallan SE, Silverman LB.Postinduction dexamethasone and individualized dosing of Escherichia Coli L-asparaginase each improve outcome of children and adolescents with newly diagnosed acute lymphoblastic leukemia: results from a randomized study--Dana-Farber Cancer Institute ALL Consortium Protocol 00-01.J Clin Oncol. 2013 Mar 20;31(9):1202-10.
    23358966
  • Lipshultz SE, Miller TL, Lipsitz SR, Neuberg DS, Dahlberg SE, Colan SD, Silverman LB, Henkel JM, Franco VI, Cushman LL, Asselin BL, Clavell LA, Athale U, Michon B, Laverdière C, Schorin MA, Larsen E, Usmani N, Sallan SE, .Continuous Versus Bolus Infusion of Doxorubicin in Children With ALL: Long-term Cardiac Outcomes.Pediatrics. 2012 Dec;130(6):1003-11.
    23166343
  • Duncan CN, Clark JJ, Silverman LB.Hematopoietic Stem Cell Transplant in Unique Pediatric Populations: Adolescents, Infants, and Children with Down Syndrome.Biol Blood Marrow Transplant. 2012 Oct 17.
    23085602
  • Hunger SP, Baruchel A, Biondi A, Evans WE, Jeha S, Loh M, Moericke A, Pieters R, Relling MV, Schmiegelow K, Schrappe M, Silverman LB, Stanulla M, Valsecchi MG, Vora A, Pui CH.The thirteenth international childhood acute lymphoblastic leukemia workshop report: La Jolla, CA, USA, December 7-9, 2011.Pediatr Blood Cancer. 2012 Sep 28.
    23024117
  • Merryman R, Stevenson KE, Gostic WJ, Neuberg D, O'Brien J, Sallan SE, Silverman LB.Asparaginase-associated myelosuppression and effects on dosing of other chemotherapeutic agents in childhood acute lymphoblastic leukemia.Pediatr Blood Cancer. 2012 Nov;59(5):925-7.
    22532399
  • Grace RF, Dahlberg SE, Neuberg D, Sallan SE, Connors JM, Neufeld EJ, Deangelo DJ, Silverman LB.The frequency and management of asparaginase-related thrombosis in paediatric and adult patients with acute lymphoblastic leukaemia treated on Dana-Farber Cancer Institute consortium protocols.British Journal of Haematology. 2011 Feb;152(4):452-9.
    21210774
  • Aricò M, Schrappe M, Hunger SP, Carroll WL, Conter V, Galimberti S, Manabe A, Saha V, Baruchel A, Vettenranta K, Horibe K, Benoit Y, Pieters R, Escherich G, Silverman LB, Pui CH, Valsecchi MG.Clinical Outcome of Children With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Treated Between 1995 and 2005.J Clin Oncol. 2010 Nov 1;28(31):4755-61.
    20876426
  • Mann G, Attarbaschi A, Schrappe M, De Lorenzo P, Peters C, Hann I, De Rossi G, Felice M, Lausen B, Leblanc T, Szczepanski T, Ferster A, Janka-Schaub G, Rubnitz J, Silverman LB, Stary J, Campbell M, Li CK, Suppiah R, Biondi A, Vora A, Valsecchi MG, Pieters R, .Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study.Blood. 2010 Oct 14;116(15):2644-50.
    20592248
  • Lipshultz SE, Scully RE, Lipsitz SR, Sallan SE, Silverman LB, Miller TL, Barry EV, Asselin BL, Athale U, Clavell LA, Larsen E, Moghrabi A, Samson Y, Michon B, Schorin MA, Cohen HJ, Neuberg DS, Orav EJ, Colan SD.Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial.Lancet Oncol. 2010 Oct;11(10):950-61.
    20850381
  • Gutierrez A, Dahlberg SE, Neuberg DS, Zhang J, Grebliunaite R, Sanda T, Protopopov A, Tosello V, Kutok J, Larson RS, Borowitz MJ, Loh ML, Ferrando AA, Winter SS, Mullighan CG, Silverman LB, Chin L, Hunger SP, Sallan SE, Look AT.Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia.J Clin Oncol. 2010 Aug 20;28(24):3816-23.
    20644084
  • Horton TM, Sposto R, Brown P, Reynolds CP, Hunger SP, Winick NJ, Raetz EA, Carroll WL, Arceci RJ, Borowitz MJ, Gaynon PS, Gore L, Jeha S, Maurer BJ, Siegel SE, Biondi A, Kearns PR, Narendran A, Silverman LB, Smith MA, Zwaan CM, Whitlock JA.Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): Review from an international consensus conference.Pediatr Blood Cancer. 2010 Jul 1;54(7):872-8.
    20127846
  • Gutierrez A, Sanda T, Ma W, Zhang J, Grebliunaite R, Dahlberg S, Neuberg D, Protopopov A, Winter SS, Larson RS, Borowitz MJ, Silverman LB, Chin L, Hunger SP, Jamieson C, Sallan SE, Look AT.Inactivation of LEF1 in T-cell acute lymphoblastic leukemia.Blood. 2010 Apr 8;115(14):2845-51.
    20124220
  • Silverman LB, Supko JG, Stevenson KE, Woodward C, Vrooman LM, Neuberg DS, Asselin BL, Athale UH, Clavell L, Cole PD, Kelly KM, Laverdière C, Michon B, Schorin M, Schwartz CL, O'Brien JE, Cohen HJ, Sallan SE.Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia.Blood. 2010 Feb 18;115(7):1351-3.
    20007809
  • Vrooman LM, Supko JG, Neuberg DS, Asselin BL, Athale UH, Clavell L, Kelly KM, Laverdière C, Michon B, Schorin M, Cohen HJ, Sallan SE, Silverman LB.Erwinia asparaginase after allergy to E. coli asparaginase in children with acute lymphoblastic leukemia.Pediatr Blood Cancer. 2010 Feb;54(2):199-205.
    19672973
  • Al-Shakfa F, Dulucq S, Brukner I, Milacic I, Ansari M, Beaulieu P, Moghrabi A, Laverdière C, Sallan SE, Silverman LB, Neuberg D, Kutok JL, Sinnett D, Krajinovic M.DNA variants in region for noncoding interfering transcript of dihydrofolate reductase gene and outcome in childhood acute lymphoblastic leukemia.Clin Cancer Res. 2009 Nov 15;15(22):6931-8.
    19861437
  • van der Linden MH, Valsecchi MG, De Lorenzo P, Möricke A, Janka G, Leblanc TM, Felice M, Biondi A, Campbell M, Hann I, Rubnitz JE, Stary J, Szczepanski T, Vora A, Ferster A, Hovi L, Silverman LB, Pieters R.Outcome of congenital acute lymphoblastic leukemia treated on the Interfant-99 protocol.Blood. 2009 Oct 29;114(18):3764-8.
    19657114
  • Sallan SE, Schrappe M, Silverman LB.Treating childhood leukemia without cranial irradiation.N Engl J Med. 2009 Sep 24;361(13):1310; author reply 1311-2.
    19776415
  • Gutierrez A,Sanda T,Grebliunaite R,Carracedo A,Salmena L,Ahn Y,Dahlberg S,Neuberg D,Moreau LA,Winter SS,Larson R,Zhang J,Protopopov A,Chin L,Pandolfi PP,Silverman LB,Hunger SP,Sallan SE,Look AT.High frequency of PTEN, PI3K and AKT abnormalities in T cell acute lymphoblastic leukemia.Blood. 2009 Jul 16;114(3):647-50.
    19458356
  • Kearney SL,Dahlberg SE,Levy DE,Voss SD,Sallan SE,Silverman LB.Clinical course and outcome in children with acute lymphoblastic leukemia and asparaginase-associated pancreatitis.Pediatr Blood Cancer. 2009 Aug;53(2):162-7.
    19405141
  • Vrooman LM,Silverman LB.Childhood acute lymphoblastic leukemia: update on prognostic factors.Curr Opin Pediatr. 2009 Feb;21(1):1-8. Review.
    19242236
  • Krivtsov AV,Feng Z,Lemieux ME,Faber J,Vempati S,Sinha AU,Xia X,Jesneck J,Bracken AP,Silverman LB,Kutok JL,Kung AL,Armstrong SA.H3K79 methylation profiles define murine and human MLL-AF4 leukemias.Cancer Cell. 2008 Nov 4;14(5):355-68.
    18977325
  • Barry EV, Vrooman LM, Dahlberg SE, Neuberg DS, Asselin BL, Athale UH, Clavell LA, Larsen EC, Moghrabi A, Samson Y, Schorin MA, Cohen HJ, Lipshultz SE, Sallan SE, Silverman LB.Absence of secondary malignant neoplasms in children with high-risk acute lymphoblastic leukemia treated with dexrazoxane.J Clin Oncol. 2008 Mar 1;26(7):1106-11.
    18309945
  • O'Neil J, Tchinda J, Gutierrez A, Moreau L, Maser RS, Wong KK, Li W, McKenna K, Liu XS, Feng B, Neuberg D, Silverman L, DeAngelo DJ, Kutok JL, Rothstein R, DePinho RA, Chin L, Lee C, Look AT.Alu elements mediate MYB gene tandem duplication in human T-ALL.J Exp Med. 2007 Dec 24;204(13):3059-66.
    18070937
  • Waber DP, Turek J, Catania L, Stevenson K, Robaey P, Romero I, Adams H, Alyman C, Jandet-Brunet C, Neuberg DS, Sallan SE, Silverman LB.Neuropsychological outcomes from a randomized trial of triple intrathecal chemotherapy compared with 18 Gy cranial radiation as CNS treatment in acute lymphoblastic leukemia: findings from Dana-Farber Cancer Institute ALL Consortium Protocol 95-01.J Clin Oncol. 2007 Nov 1;25(31):4914-21.
    17971588
  • Silverman LB.Acute lymphoblastic leukemia in infancy.Pediatr Blood Cancer. 2007 Dec;49(7 Suppl):1070-3. Review.
    17943956
  • Rodig SJ, Payne EG, Degar BA, Rollins B, Feldman AL, Jaffe ES, Androkites A, Silverman LB, Longtine JA, Kutok JL, Fleming MD, Aster JC.Aggressive Langerhans cell histiocytosis following T-ALL: clonally related neoplasms with persistent expression of constitutively active NOTCH1.Am J Hematol. 2008 Feb;83(2):116-21.
    17874453
  • Zhou J, Goldwasser MA, Li A, Dahlberg SE, Neuberg D, Wang H, Dalton V, McBride KD, Sallan SE, Silverman LB, Gribben JG.Quantitative analysis of minimal residual disease predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL consortium protocol 95-01.Blood. 2007 Sep 1;110(5):1607-11.
    17485550
  • Nachman JB, Heerema NA, Sather H, Camitta B, Forestier E, Harrison CJ, Dastugue N, Schrappe M, Pui CH, Basso G, Silverman LB, Janka GE.Outcome of treatment in children with hypodiploid acute lymphoblastic leukemia.Blood. 2007 Aug 15;110(4):1112-5.
    17473063
  • Pieters R, Schrappe M, De Lorenzo P, Hann I, De Rossi G, Felice M, Hovi L, LeBlanc T, Szczepanski T, Ferster A, Janka G, Rubnitz J, Silverman L, Stary J, Campbell M, Li CK, Mann G, Suppiah R, Biondi A, Vora A, Valsecchi MG.A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.Lancet. 2007 Jul 21;370(9583):240-50.
    17658395
  • Barry E, DeAngelo DJ, Neuberg D, Stevenson K, Loh ML, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin M, Cohen HJ, Sallan SE, Silverman LB.Favorable outcome for adolescents with acute lymphoblastic leukemia treated on Dana-Farber Cancer Institute Acute Lymphoblastic Leukemia Consortium Protocols.J Clin Oncol. 2007 Mar 1;25(7):813-9.
    17327603
  • Moghrabi A, Levy DE, Asselin B, Barr R, Clavell L, Hurwitz C, Samson Y, Schorin M, Dalton VK, Lipshultz SE, Neuberg DS, Gelber RD, Cohen HJ, Sallan SE, Silverman LB.Results of the Dana-Farber Cancer Institute ALL Consortium Protocol 95-01 for children with acute lymphoblastic leukemia.Blood. 2007 Feb 1;109(3):896-904.
    17003366
  • Loh ML, Goldwasser MA, Silverman LB, Poon WM, Vattikuti S, Cardoso A, Neuberg DS, Shannon KM, Sallan SE, Gilliland DG.Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute Consortium Protocol 95-01.Blood. 2006 Jun 1;107(11):4508-13.
    16493009
  • Li A, Goldwasser MA, Zhou J, Armstrong SA, Wang H, Dalton V, Fletcher JA, Sallan SE, Silverman LB, Gribben JG.Distinctive IGH gene segment usage and minimal residual disease detection in infant acute lymphoblastic leukaemias.Br J Haematol. 2005 Oct;131(2):185-92.
    16197448
  • Haining WN, Neuberg DS, Keczkemethy HL, Evans JW, Rivoli S, Gelman R, Rosenblatt HM, Shearer WT, Guenaga J, Douek DC, Silverman LB, Sallan SE, Guinan EC, Nadler LM.Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leukemia.Blood. 2005 Sep 1;106(5):1749-54.
    15920008
  • Moorman AV, Raimondi SC, Pui CH, Baruchel A, Biondi A, Carroll AJ, Forestier E, Gaynon PS, Harbott J, Harms DO, Heerema N, Pieters R, Schrappe M, Silverman LB, Vilmer E, Harrison CJ,.No prognostic effect of additional chromosomal abnormalities in children with acute lymphoblastic leukemia and 11q23 abnormalities.Leukemia. 2005 Apr;19(4):557-63.
    15744345
  • Haining WN, Cardoso AA, Keczkemethy HL, Fleming M, Neuberg D, DeAngelo DJ, Stone RM, Galinsky I, Silverman LB, Sallan SE, Nadler LM, Guinan EC.Failure to define window of time for autologous tumor vaccination in patients with newly diagnosed or relapsed acute lymphoblastic leukemia.Exp Hematol. 2005 Mar;33(3):286-94.
    15730852
  • Weng AP, Ferrando AA, Lee W, Morris JP, Silverman LB, Sanchez-Irizarry C, Blacklow SC, Look AT, Aster JC.Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.Science. 2004 Oct 8;306(5694):269-71.
    15472075
  • Lipshultz SE, Rifai N, Dalton VM, Levy DE, Silverman LB, Lipsitz SR, Colan SD, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin MA, Gelber RD, Sallan SE.The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia.N Engl J Med. 2004 Jul 8;351(2):145-53.
    15247354
  • Waber DP, Silverman LB, Catania L, Mautz W, Rue M, Gelber RD, Levy DE, Goldwasser MA, Adams H, Dufresne A, Metzger V, Romero I, Tarbell NJ, Dalton VK, Sallan SE.Outcomes of a randomized trial of hyperfractionated cranial radiation therapy for treatment of high-risk acute lymphoblastic leukemia: therapeutic efficacy and neurotoxicity.J Clin Oncol. 2004 Jul 1;22(13):2701-7.
    15226337
  • Li A, Rue M, Zhou J, Wang H, Goldwasser MA, Neuberg D, Dalton V, Zuckerman D, Lyons C, Silverman LB, Sallan SE, Gribben JG.Utilization of Ig Heavy-Chain Variable, Diversity and Joining Gene Segments in Children with B-lineage Acute Lymphoblastic Leukemia: Implications for the Mechanisms of VDJ Recombination and for Pathogenesis.Blood. 2004 Jun 15;103(12):4602-9.
    15010366
  • Armstrong SA, Mabon ME, Silverman LB, Li A, Gribben JG, Fox EA, Sallan SE, Korsmeyer SJ.FLT3 mutations in childhood acute lymphoblastic leukemia.Blood. 2004 May 1;103(9):3544-6.
    14670924
  • Goldberg JM, Silverman LB, Levy DE, Dalton VK, Gelber RD, Lehmann L, Cohen HJ, Sallan SE, Asselin BL.Childhood T-cell acute lymphoblastic leukemia: the Dana-Farber Cancer Institute acute lymphoblastic leukemia consortium experience.J Clin Oncol. 2003 Oct 1;21(19):3616-22.
    14512392
  • Li A, Zhou J, Zuckerman D, Rue M, Dalton V, Lyons C, Silverman LB, Sallan SE, Gribben JG.Sequence analysis of clonal immunoglobulin and T-cell receptor gene rearrangements in children with acute lymphoblastic leukemia at diagnosis and at relapse: implications for pathogenesis and for the clinical utility of PCR-based methods of minimal residu.Blood. 2003 Dec 15;102(13):4520-6.
    12946997
  • Dalton VK, Rue M, Silverman LB, Gelber RD, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin M, Tarbell NJ, Sallan SE, Cohen LE.Height and weight in children treated for acute lymphoblastic leukemia: relationship to CNS treatment.J Clin Oncol. 2003 Aug 1;21(15):2953-60.
    12885815
  • Silverman LB, Sallan SE.Newly diagnosed childhood acute lymphoblastic leukemia: update on prognostic factors and treatment.Curr Opin Hematol. 2003 Jul;10(4):290-6.
    12799535
  • Ferrando AA, Armstrong SA, Neuberg DS, Sallan SE, Silverman LB, Korsmeyer SJ, Look AT.Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.Blood. 2003 Jul 1;102(1):262-8.
    12637319
  • Armstrong SA, Kung AL, Mabon ME, Silverman LB, Stam RW, Den Boer ML, Pieters R, Kersey JH, Sallan SE, Fletcher JA, Golub TR, Griffin JD, Korsmeyer SJ.Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.Cancer Cell. 2003 Feb;3(2):173-83.
    12620411
  • LeClerc JM, Billett AL, Gelber RD, Dalton V, Tarbell N, Lipton JM, Barr R, Clavell LA, Asselin B, Hurwitz C, Schorin M, Lipshultz SE, Declerck L, Silverman LB, Cohen HJ, Sallan SE.Treatment of childhood acute lymphoblastic leukemia: results of Dana-Farber ALL Consortium Protocol 87-01.J Clin Oncol. 2002 Jan 1;20(1):237-46.
    11773175
  • Armstrong SA, Staunton JE, Silverman LB, Pieters R, den Boer ML, Minden MD, Sallan SE, Lander ES, Golub TR, Korsmeyer SJ.MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia.Nat Genet. 2002 Jan;30(1):41-7.
    11731795
  • Waber DP, Shapiro BL, Carpentieri SC, Gelber RD, Zou G, Dufresne A, Romero I, Tarbell NJ, Silverman LB, Sallan SE.Excellent therapeutic efficacy and minimal late neurotoxicity in children treated with 18 grays of cranial radiation therapy for high-risk acute lymphoblastic leukemia: a 7-year follow-up study of the Dana-Farber Cancer Institute Consortium Protocol 87-01.Cancer. 2001 Jul 1;92(1):15-22.
    11443604
  • Strauss AJ, Su JT, Dalton VM, Gelber RD, Sallan SE, Silverman LB.Bony morbidity in children treated for acute lymphoblastic leukemia.J Clin Oncol. 2001 Jun 15;19(12):3066-72.
    11408503
  • Silverman LB, Gelber RD, Dalton VK, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin MA, Arkin S, Declerck L, Cohen HJ, Sallan SE.Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01.Blood. 2001 Mar 1;97(5):1211-8.
    11222362
  • Silverman LB, Declerck L, Gelber RD, Dalton VK, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin MA, Lipton JM, Cohen HJ, Sallan SE.Results of Dana-Farber Cancer Institute Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1981-1995).Leukemia. 2000 Dec;14(12):2247-56.
    11187916
  • Waber DP, Carpentieri SC, Klar N, Silverman LB, Schwenn M, Hurwitz CA, Mullenix PJ, Tarbell NJ, Sallan SE.Cognitive sequelae in children treated for acute lymphoblastic leukemia with dexamethasone or prednisone.J Pediatr Hematol Oncol. 2000 May-Jun;22(3):206-13.
    10864051
  • Hurwitz CA, Silverman LB, Schorin MA, Clavell LA, Dalton VK, Glick KM, Gelber RD, Sallan SE.Substituting dexamethasone for prednisone complicates remission induction in children with acute lymphoblastic leukemia.Cancer. 2000 Apr 15;88(8):1964-9.
    10760775
  • Silverman LB, Gelber RD, Young ML, Dalton VK, Barr RD, Sallan SE.Induction failure in acute lymphoblastic leukemia of childhood.Cancer. 1999 Mar 15;85(6):1395-404.
    10189148
  • Loh ML, Silverman LB, Young ML, Neuberg D, Golub TR, Sallan SE, Gilliland DG.Incidence of TEL/AML1 fusion in children with relapsed acute lymphoblastic leukemia.Blood. 1998 Dec 15;92(12):4792-7.
    9845546
  • Silverman LB, McLean TW, Gelber RD, Donnelly MJ, Gilliland DG, Tarbell NJ, Sallan SE.Intensified therapy for infants with acute lymphoblastic leukemia: results from the Dana-Farber Cancer Institute Consortium.Cancer. 1997 Dec 15;80(12):2285-95.
    9404706
  • Silverman LB, Weinstein HJ.Treatment of childhood leukemia.Curr Opin Oncol. 1997 Jan;9(1):26-33.
    9090491