• Home
  • News
  • Calendar
  • About DF/HCC
  • Membership
  • Visitor Center

Daniel J. DeAngelo, MD, PhD

Publications

  • Wang M, Medeiros BC, Erba HP, DeAngelo DJ, Giles FJ, Swords RT.Targeting protein neddylation: a novel therapeutic strategy for the treatment of cancer.Expert Opin Ther Targets. 2011 Mar;15(3):253-64.
    21219242
  • Grace RF, Dahlberg SE, Neuberg D, Sallan SE, Connors JM, Neufeld EJ, Deangelo DJ, Silverman LB.The frequency and management of asparaginase-related thrombosis in paediatric and adult patients with acute lymphoblastic leukaemia treated on Dana-Farber Cance
    21210774
  • Roper N, Deangelo DJ, Kuo F, Cin PD, Ghobrial I, Aster JC.An asymptomatic 61-year-old man with BCR-ABL-positive bone marrow following autologous transplantation for multiple myeloma.Am J Hematol. 2010 Dec;85(12):944-6.
    20730794
  • Singh H, Werner L, Deangelo D, Ballen K, Amrein P, Wadleigh M, Neuberg D, Fox E, Stone R, Attar E.Clinical outcome of patients with acute promyelocytic leukemia and FLT3 mutations.Am J Hematol. 2010 Dec;85(12):956-7.
    20981678
  • Fischer T, Stone RM, Deangelo DJ, Galinsky I, Estey E, Lanza C, Fox E, Ehninger G, Feldman EJ, Schiller GJ, Klimek VM, Nimer SD, Gilliland DG, Dutreix C, Huntsman-Labed A, Virkus J, Giles FJ.Phase IIB trial of oral Midostaurin (PKC412), the FMS-like tyros
    20733134
  • Hammond SP, Marty FM, Bryar JM, DeAngelo DJ, Baden LR.Invasive fungal disease in patients treated for newly diagnosed acute leukemia.Am J Hematol. 2010 Sep;85(9):695-9.
    20652970
  • Kolitz JE, George SL, Marcucci G, Vij R, Powell BL, Allen SL, DeAngelo DJ, Shea TC, Stock W, Baer MR, Hars V, Maharry K, Hoke E, Vardiman JW, Bloomfield CD, Larson RA, .P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for pat
    20522709
  • Alyea EP, Deangelo DJ, Moldrem J, Pagel JM, Przepiorka D, Riddell S, Sadelin M, Young JW, Giralt S, Bishop M.NCI First International Workshop on the Biology, Prevention and Treatment of Relapse after Allogeneic Hematopoietic Cell Transplantation: Report f
    20580849
  • Ghobrial IM, Gertz M, Laplant B, Camoriano J, Hayman S, Lacy M, Chuma S, Harris B, Leduc R, Rourke M, Ansell SM, Deangelo D, Dispenzieri A, Bergsagel L, Reeder C, Anderson KC, Richardson PG, Treon SP, Witzig TE.Phase II trial of the oral mammalian target
    20142598
  • Dal Cin P, Aster JC, DeAngelo DJ.When to go FISHing.Am J Clin Pathol. 2010 Mar;133(3):351-3.
    20154272
  • DeAngelo DJ, Attar EC.Use of dasatinib and nilotinib in imatinib-resistant chronic myeloid leukemia: translating preclinical findings to clinical practice.Leuk Lymphoma. 2010 Mar;51(3):363-75.
    20038231
  • Schiller GJ, O'Brien SM, Pigneux A, Deangelo DJ, Vey N, Kell J, Solomon S, Stuart RK, Karsten V, Cahill AL, Albitar MX, Giles FJ.Single-agent laromustine, a novel alkylating agent, has significant activity in older patients with previously untreated p
    20026800
  • Yoda A, Yoda Y, Chiaretti S, Bar-Natan M, Mani K, Rodig SJ, West N, Xiao Y, Brown JR, Mitsiades C, Sattler M, Kutok JL, DeAngelo DJ, Wadleigh M, Piciocchi A, Dal Cin P, Bradner JE, Griffin JD, Anderson KC, Stone RM, Ritz J, Foà R, Aster JC, Frank DA, Wei
    20018760
  • O'Brien S, Berman E, Borghaei H, Deangelo DJ, Devetten MP, Devine S, Erba HP, Gotlib J, Jagasia M, Moore JO, Mughal T, Pinilla-Ibarz J, Radich JP, Shah Md NP, Shami PJ, Smith BD, Snyder DS, Tallman MS, Talpaz M, Wetzler M, .NCCN clinical practice gui
    19878641
  • DeAngelo DJ.Nelarabine for the treatment of patients with relapsed or refractory T-cell acute lymphoblastic leukemia or lymphoblastic lymphoma.Hematol Oncol Clin North Am. 2009 Oct;23(5):1121-35, vii-viii. Review.
    19825456
  • Hahn CK, Berchuck JE, Ross KN, Kakoza RM, Clauser K, Schinzel AC, Ross L, Galinsky I, Davis TN, Silver SJ, Root DE, Stone RM, DeAngelo DJ, Carroll M, Hahn WC, Carr SA, Golub TR, Kung AL, Stegmaier K.Proteomic and genetic approaches identify Syk as an AML
    19800574
  • Stone RM, DeAngelo DJ.Screens, iron, and leukemia.Blood. 2009 Oct 1;114(14):2857-8.
    19797531
  • Dickinson M, Ritchie D, DeAngelo DJ, Spencer A, Ottmann OG, Fischer T, Bhalla KN, Liu A, Parker K, Scott JW, Bishton M, Prince HM.Preliminary evidence of disease response to the pan deacetylase inhibitor panobinostat (LBH589) in refractory Hodgkin Lymphom
    19663825
  • Borrello IM, Levitsky HI, Stock W, Sher D, Qin L, DeAngelo DJ, Alyea EP, Stone RM, Damon LE, Linker CA, Maslyar DJ, Hege KM.Granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting cellular immunotherapy in combination with autologous stem cell
    19556425
  • Patel TV,Rennke HG,Sloan JM,Deangelo DJ,Charytan DM.A Forgotten Cause of Kidney Injury in Chronic Myelomonocytic Leukemia.Am J Kidney Dis. 2009 Jul;54(1):159-64.
    19185401
  • Corsello SM,Roti G,Ross KN,Chow KT,Galinsky I,Deangelo DJ,Stone RM,Kung AL,Golub TR,Stegmaier K.Identification of AML1-ETO modulators by chemical genomics.Blood. 2009 Jun 11;113(24):6193-205.
    19377049
  • Koreth J, Schlenk R, Kopecky KJ, Honda S, Sierra J, Djulbegovic BJ, Wadleigh M, DeAngelo DJ, Stone RM, Sakamaki H, Appelbaum FR, Döhner H, Antin JH, Soiffer RJ, Cutler C.Allogeneic stem cell transplantation for acute myeloid leukemia in first complete re
    19509382
  • Fonseca C,Soiffer R,Ho V,Vanneman M,Jinushi M,Ritz J,Neuberg D,Stone R,DeAngelo D,Dranoff G.Protein disulfide isomerases are antibody targets during immune-mediated tumor destruction.Blood. 2009 Feb 19;113(8):1681-8.
    19008459
  • Stone RM,DeAngelo DJ,Janosova A,Galinsky I,Canning C,Ritz J,Soiffer RJ.Low dose interleukin-2 following intensification therapy with high dose cytarabine for acute myelogenous leukemia in first complete remission.Am J Hematol. 2008 Oct;83(10):771-7.
    18756547
  • Kesari S,Akar S,Saad A,Drappatz J,Koralnik IJ,DeAngelo DJ.Progressive multifocal leukoencephalopathy in a patient with relapsed acute myelogenous leukemia.J Clin Oncol. 2008 Aug 1;26(22):3804-7.
    18669471
  • Stone RM,Donohue KA,Stock W,Hars V,Linker CA,Shea T,Deangelo DJ,Marcucci G,Bloomfield CD,Larson RA.A phase II study of continuous infusion homoharringtonine and cytarabine in newly diagnosed patients with chronic myeloid leukemia: CALGB study 19804.Cancer
    18670778
  • Poitras JL,Dal Cin P,Aster JC,Deangelo DJ,Morton CC.Novel SSBP2-JAK2 fusion gene resulting from a t(5;9)(q14.1;p24.1) in pre-B acute lymphocytic leukemia.Genes Chromosomes Cancer. 2008 Oct;47(10):884-9.
    18618714
  • Kesari S,Drappatz J,Akar S,Vergilio JA,Wen PY,Soiffer RJ,Stone RM,Deangelo DJ.Recurrent acute promyelocytic leukemia presenting as a sacral nerve root mass.J Clin Oncol. 2008 Jul 1;26(19):3279-81.
    18591563
  • Schwarzberg AB,Alexander CB,DeAngelo DJ,Helfgott SM.Clinical problem-solving. A joint venture.N Engl J Med. 2008 Jun 5;358(23):2496-501.
    18525046
  • Abel GA, Deangelo DJ, Connors JM, Sholl LM, McCaffrey RP, Longtine JA.Clinical JAK2V617F mutation testing: Limited utility for general hospital patients with venous and arterial thromboses in common locations.Am J Hematol. 2008 Jun;83(6):519-20.
    18306358
  • Giles FJ, DeAngelo DJ, Baccarani M, Deininger M, Guilhot F, Hughes T, Mauro M, Radich J, Ottmann O, Cortes J.Optimizing outcomes for patients with advanced disease in chronic myelogenous leukemia.Semin Oncol. 2008 Feb;35(1 Suppl 1):S1-17; quiz S18-20. Rev
    18346528
  • Attar EC, De Angelo DJ, Supko JG, D'Amato F, Zahrieh D, Sirulnik A, Wadleigh M, Ballen KK, McAfee S, Miller KB, Levine J, Galinsky I, Trehu EG, Schenkein D, Neuberg D, Stone RM, Amrein PC.Phase I and pharmacokinetic study of bortezomib in combination
    18316568
  • O'Neil J, Tchinda J, Gutierrez A, Moreau L, Maser RS, Wong KK, Li W, McKenna K, Liu XS, Feng B, Neuberg D, Silverman L, DeAngelo DJ, Kutok JL, Rothstein R, DePinho RA, Chin L, Lee C, Look AT.Alu elements mediate MYB gene tandem duplication in human T-
    18070937
  • Deangelo DJ, Yu D, Johnson JL, Coutre SE, Stone RM, Stopeck AT, Gockerman JP, Mitchell BS, Appelbaum FR, Larson RA.Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphom
    17344466
  • Armand P, Kim HT, Deangelo DJ, Ho VT, Cutler CS, Stone RM, Ritz J, Alyea EP, Antin JH, Soiffer RJ.Impact of Cytogenetics on Outcome of De Novo and Therapy-Related AML and MDS after Allogeneic Transplantation.Biol Blood Marrow Transplant. 2007 Jun;13(6):65
    17531775
  • Barry E, DeAngelo DJ, Neuberg D, Stevenson K, Loh ML, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin M, Cohen HJ, Sallan SE, Silverman LB.Favorable outcome for adolescents with acute lymphoblastic leukemia treated on Dana-Farbe
    17327603
  • Alyea EP, Kim HT, Ho V, Cutler C, DeAngelo DJ, Stone R, Ritz J, Antin JH, Soiffer RJ.Impact of conditioning regimen intensity on outcome of allogeneic hematopoietic cell transplantation for advanced acute myelogenous leukemia and myelodysplastic syndrome.
    17067911
  • McKoy JM, Angelotta C, Bennett CL, Tallman MS, Wadleigh M, Evens AM, Kuzel TM, Trifilio SM, Raisch DW, Kell J, Deangelo DJ, Giles FJ.Gemtuzumab ozogamicin-associated sinusoidal obstructive syndrome (SOS): An overview from the research on adverse drug even
    16959316
  • DeAngelo DJ, Stone RM, Heaney ML, Nimer SD, Paquette RL, Klisovic RB, Caligiuri MA, Cooper MR, Lecerf JM, Karol MD, Sheng S, Holford N, Curtin PT, Druker BJ, Heinrich MC.Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patien
    16902153
  • Pikman Y, Lee BH, Mercher T, McDowell E, Ebert BL, Gozo M, Cuker A, Wernig G, Moore S, Galinsky I, Deangelo DJ, Clark JJ, Lee SJ, Golub TR, Wadleigh M, Gilliland DG, Levine RL.MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid M
    16834459
  • Deangelo DJ.The treatment of adolescents and young adults with acute lymphoblastic leukemia.Hematology Am Soc Hematol Educ Program. 2005:123-30.
    16304369
  • Ligon AH, DeAngelo DJ, Atkins L, Dal Cin P.Isochromosome of a deleted 20q may be a relatively common abnormality in myeloid malignancies.Cancer Genet Cytogenet. 2005 Oct 1;162(1):89-91.
    16157208
  • Christacos NC, Sherman L, Roy A, DeAngelo DJ, Dal Cin P.Is the cryptic interstitial deletion of 8q24 surrounding MYC a common mechanism in the formation of double minute chromosome?.Cancer Genet Cytogenet. 2005 Aug;161(1):90-2.
    16080965
  • Stegmaier K, Corsello SM, Ross KN, Wong JS, Deangelo DJ, Golub TR.Gefitinib induces myeloid differentiation of acute myeloid leukemia.Blood. 2005 Oct 15;106(8):2841-8.
    15998836
  • Haining WN, Cardoso AA, Keczkemethy HL, Fleming M, Neuberg D, DeAngelo DJ, Stone RM, Galinsky I, Silverman LB, Sallan SE, Nadler LM, Guinan EC.Failure to define window of time for autologous tumor vaccination in patients with newly diagnosed or relapsed a
    15730852
  • Alyea EP, Kim HT, Ho VT, Cutler C, Gribben J, DeAngelo DJ, Lee SJ, Windawi S, Ritz J, Stone RM, Antin JH, Soiffer RJ.Comparative outcome of non-myeloablative and myeloablative allogeneic hematopoietic cell transplantation for patients greater than fifty y
    15459007
  • Stone RM, DeAngelo DJ, Klimek V, Galinsky I, Estey E, Nimer SD, Grandin W, Lebwohl D, Wang Y, Cohen P, Fox EA, Neuberg D, Clark J, Gilliland DG, Griffin JD.Acute myeloid leukemia patients with an activating mutation in FLT3 respond to a small molecule FLT
    15345597
  • Levine RL, Wadleigh M, Sternberg DW, Wlodarska I, Galinsky I, Stone RM, DeAngelo DJ, Gilliland DG, Cools J.KIAA1509 is a novel PDGFRB fusion partner in imatinib-responsive myeloproliferative disease associated with a t(5;14)(q33;q32).Leukemia. 2005 Jan;19
    15496975
  • Gong J, Koido S, Kato Y, Tanaka Y, Chen D, Jonas A, Galinsky I, DeAngelo D, Avigan D, Kufe D, Stone R.Induction of anti-leukemic cytotoxic T lymphocytes by fusion of patient-derived dendritic cells with autologous myeloblasts.Leuk Res. 2004 Dec;28(12):130
    15475072
  • Chen J, Deangelo DJ, Kutok JL, Williams IR, Lee BH, Wadleigh M, Duclos N, Cohen S, Adelsperger J, Okabe R, Coburn A, Galinsky I, Huntly B, Cohen PS, Meyer T, Fabbro D, Roesel J, Banerji L, Griffin JD, Xiao S, Fletcher JA, Stone RM, Gilliland DG.PKC412 inh
    15448205
  • Wadleigh M, DeAngelo DJ, Griffin JD, Stone RM.After chronic myelogenous leukemia: tyrosine kinase inhibitors in other hematologic malignancies.Blood. 2005 Jan 1;105(1):22-30.
    15358622
  • Jiang J, Paez JG, Lee JC, Bo R, Stone RM, DeAngelo DJ, Galinsky I, Wolpin BM, Jonasova A, Herman P, Fox EA, Boggon TJ, Eck MJ, Weisberg E, Griffin JD, Gilliland DG, Meyerson M, Sellers WR.Identification and Characterization of a Novel Activating Mutation
    15178581
  • DeAngelo DJ, Hochberg EP, Alyea EP, Longtine J, Lee S, Galinsky I, Parekkedon B, Ritz J, Antin JH, Stone RM, Soiffer RJ.Extended follow-up of patients treated with imatinib mesylate (gleevec) for chronic myelogenous leukemia relapse after allogeneic trans
    15297408
  • Sekeres MA, Stone RM, Zahrieh D, Neuberg D, Morrison V, De Angelo DJ, Galinsky I, Lee SJ.Decision-making and quality of life in older adults with acute myeloid leukemia or advanced myelodysplastic syndrome.Leukemia. 2004 Apr;18(4):809-16.
    14762444
  • Wadleigh M, Richardson PG, Zahrieh D, Lee SJ, Cutler C, Ho V, Alyea EP, Antin JH, Stone RM, Soiffer RJ, DeAngelo DJ.Prior gemtuzumab ozogamicin exposure significantly increases the risk of veno-occlusive disease in patients who undergo myeloablative allog
    12738663
  • Cools J, DeAngelo DJ, Gotlib J, Stover EH, Legare RD, Cortes J, Kutok J, Clark J, Galinsky I, Griffin JD, Cross NC, Tefferi A, Malone J, Alam R, Schrier SL, Schmid J, Rose M, Vandenberghe P, Verhoef G, Boogaerts M, Wlodarska I, Kantarjian H, Marynen P, Co
    12660384
  • Wu CJ, Neuberg D, Chillemi A, McLaughlin S, Hochberg EP, Galinsky I, DeAngelo D, Soiffer RJ, Alyea EP, Capdeville R, Stone RM, Ritz J.Quantitative monitoring of BCR/ABL transcript during STI-571 therapy.Leuk Lymphoma. 2002 Dec;43(12):2281-9.
    12613514
  • Alyea EP, Weller E, Fisher DC, Freedman AS, Gribben JG, Lee S, Schlossman RL, Stone RM, Friedberg J, DeAngelo D, Liney D, Windawi S, Ng A, Mauch P, Antin JH, Soiffer RJ.Comparable outcome with T-cell-depleted unrelated-donor versus related-donor allogenei
    12463479
  • Sarraf P, Mueller E, Jones D, King FJ, DeAngelo DJ, Partridge JB, Holden SA, Chen LB, Singer S, Fletcher C, Spiegelman BM.Differentiation and reversal of malignant changes in colon cancer through PPARgamma.Nat Med. 1998 Sep;4(9):1046-52.
    9734398
  • DeAngelo DJ, DeFalco J, Rybacki L, Childs G.The embryonic enhancer-binding protein SSAP contains a novel DNA-binding domain which has homology to several RNA-binding proteins.Mol Cell Biol. 1995 Mar;15(3):1254-64.
    7862119
  • DeAngelo DJ, DeFalco J, Childs G.Purification and characterization of the stage-specific embryonic enhancer-binding protein SSAP-1.Mol Cell Biol. 1993 Mar;13(3):1746-58.
    8441410
  • Lai ZC, DeAngelo DJ, DiLiberto M, Childs G.An embryonic enhancer determines the temporal activation of a sea urchin late H1 gene.Mol Cell Biol. 1989 Jun;9(6):2315-21.
    2548079