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Alex, Shu-Wing Ng, PhD


  • Lui KO, Howie D, Ng SW, Liu S, Chien KR, Waldmann H.Tolerance induction to human stem cell transplants with extension to their differentiated progeny.Nat Commun. 2014;5:5629.
  • Shoni M, Lui KO, Vavvas DG, Muto MG, Berkowitz RS, Vlahos N, Ng SW.Protein kinases and associated pathways in pluripotent state and lineage differentiation.Curr Stem Cell Res Ther. 2014;9(5):366-87. Review.
  • Ng SK, McLachlan GJ, Wang K, Nagymanyoki Z, Liu S, Ng SW.Inference on differences between classes using cluster-specific contrasts of mixed effects.Biostatistics. 2014 Jun 23.
  • Benjamin DI, Louie SM, Mulvihill MM, Kohnz RA, Li DS, Chan LG, Sorrentino A, Bandyopadhyay S, Cozzo A, Ohiri A, Goga A, Ng SW, Nomura DK.Inositol Phosphate Recycling Regulates Glycolytic and Lipid Metabolism That Drives Cancer Aggressiveness.ACS Chem Biol. 2014 Apr 28.
  • Esselen KM, Ng SK, Hua Y, White M, Jimenez CA, Welch WR, Drapkin R, Berkowitz RS, Ng SW.Endosalpingiosis as it relates to tubal, ovarian and serous neoplastic tissues: an immunohistochemical study of tubal and M├╝llerian antigens.Gynecol Oncol. 2014 Feb;132(2):316-21.
  • Shoni M, Nagymanyoki Z, Vitonis AF, Jimenez C, Ng SW, Quade BJ, Berkowitz RS.p-21-Activated kinase-1, -4 and -6 and estrogen receptor expression pattern in normal placenta and gestational trophoblastic diseases.Gynecol Oncol. 2013 Dec;131(3):759-63.
  • Zhou S, Tang L, Wang H, Dai J, Zhang J, Shen L, Ng SW, Berkowitz RS.Overexpression of c-Abl predicts unfavorable outcome in epithelial ovarian cancer.Gynecol Oncol. 2013 Oct;131(1):69-76.
  • Greer AH, Yong T, Fennell K, Moustafa YW, Fowler M, Galiano F, Ng SW, Berkowitz RS, Cardelli J, Meyers S, Davis JN.Knockdown of core binding factor╬▓ alters sphingolipid metabolism.J Cell Physiol. 2013 Dec;228(12):2350-64.
  • Barroilhet L, Yang J, Hasselblatt K, Paranal RM, Ng SK, Rauh-Hain JA, Welch WR, Bradner JE, Berkowitz RS, Ng SW.C-terminal binding protein-2 regulates response of epithelial ovarian cancer cells to histone deacetylase inhibitors.Oncogene. 2013 Aug 15;32(33):3896-903.
  • May T, Yang J, Shoni M, Liu S, He H, Gali R, Ng SK, Crum C, Berkowitz RS, Ng SW.BRCA1 expression is epigenetically repressed in sporadic ovarian cancer cells by overexpression of C-terminal binding protein 2.Neoplasia. 2013 Jun;15(6):600-8.
  • Worley MJ, Welch WR, Berkowitz RS, Ng SW.Endometriosis-associated ovarian cancer: a review of pathogenesis.Int J Mol Sci. 2013;14(3):5367-79.
  • Saw YT, Yang J, Ng SK, Liu S, Singh S, Singh M, Welch WR, Tsuda H, Fong WP, Thompson D, Vasiliou V, Berkowitz RS, Ng SW.Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures.BMC Cancer. 2012;12:329.
  • Rodriguez N, Yang J, Hasselblatt K, Liu S, Zhou Y, Rauh-Hain JA, Ng SK, Choi PW, Fong WP, Agar NY, Welch WR, Berkowitz RS, Ng SW.Casein kinase I epsilon interacts with mitochondrial proteins for the growth and survival of human ovarian cancer cells.EMBO Mol Med. 2012 Sep;4(9):952-63.
  • Singh M, Kindelberger D, Nagymanyoki Z, Ng SW, Quick CM, Yamamoto H, Fichorova R, Fulop V, Berkowitz RS.Vascular endothelial growth factors and their receptors and regulators in gestational trophoblastic diseases and normal placenta.J Reprod Med.;57(5-6):197-203.
  • Ifediba MA, Medarova Z, Ng SW, Yang J, Moore A.siRNA delivery to CNS cells using a membrane translocation peptide.Bioconjug Chem. 2010 May 19;21(5):803-6.
  • Nomura DK, Long JZ, Niessen S, Hoover HS, Ng SW, Cravatt BF.Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis.Cell. 2010 Jan 8;140(1):49-61.
  • Tang L, Yang J, Ng SK, Rodriguez N, Choi PW, Vitonis A, Wang K, McLachlan GJ, Caiazzo RJ, Liu BC, Welch WR, Cramer DW, Berkowitz RS, Ng SW.Autoantibody profiling to identify biomarkers of key pathogenic pathways in mucinous ovarian cancer.Eur J Cancer. 2010 Jan;46(1):170-9.
  • Medarova Z,Kumar M,Ng SW,Yang J,Barteneva N,Evgenov NV,Petkova V,Moore A.Multifunctional magnetic nanocarriers for image-tagged SiRNA delivery to intact pancreatic islets.Transplantation. 2008 Nov 15;86(9):1170-7.
  • Ehrlich JR, Tang L, Caiazzo RJ Jr, Cramer DW, Ng SK, Ng SW, Liu BC.The "reverse capture" autoantibody microarray : an innovative approach to profiling the autoantibody response to tissue-derived native antigens.Methods Mol Biol. 2008;441:175-92.
  • Ng SK, McLachlan GJ, Wang K, Ben-Tovim Jones L, Ng SW.A mixture model with random-effects components for clustering correlated gene-expression profiles.Bioinformatics. 2006 Jul 15;22(14):1745-52.
  • Huang KC, Park DC, Ng SK, Lee JY, Ni X, Ng WC, Bandera CA, Welch WR, Berkowitz RS, Mok SC, Ng SW.Selenium binding protein 1 in ovarian cancer.Int J Cancer. 2006 May 15;118(10):2433-40.
  • Jiao W,Lin HM,Timmons J,Nagaich AK,Ng SW,Misteli T,Rane SG.E2F-dependent repression of topoisomerase II regulates heterochromatin formation and apoptosis in cells with melanoma-prone mutation.Cancer Res. 2005 May 15;65(10):4067-77.
  • Saxena D,Yiu GK,Ni X,Huang KC,Mantovani R,Jacquemin-Sablon AG,Ng SW.Characterization of promoter elements involved in the down-regulation of topoisomerase IIalpha expression in a drug-resistant cell line.Gene. 2004 Nov 10;342(1):145-55.
  • Ni X,Zhang W,Huang KC,Wang Y,Ng SK,Mok SC,Berkowitz RS,Ng SW.Characterisation of human kallikrein 6/protease M expression in ovarian cancer.Br J Cancer. 2004 Aug 16;91(4):725-31.
  • Huang KC, Rao PH, Lau CC, Heard E, Ng SK, Brown C, Mok SC, Berkowitz RS, Ng SW.Relationship of XIST expression and responses of ovarian cancer to chemotherapy.Mol Cancer Ther. 2002 Aug;1(10):769-76.
  • Wei SH, Chen CM, Strathdee G, Harnsomburana J, Shyu CR, Rahmatpanah F, Shi H, Ng SW, Yan PS, Nephew KP, Brown R, Huang TH.Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers.Clin Cancer Res. 2002 Jul;8(7):2246-52.
  • Seiden MV, Ng SW, Supko JG, Ryan DP, Clark JW, Lynch T, Huang KC, Kwiatkowski D, Skarin A, Eder JP.A phase I clinical trial of sequentially administered doxorubicin and topotecan in refractory solid tumors.Clin Cancer Res. 2002 Mar;8(3):691-7.
  • Yiu GK, Chan WY, Ng SW, Chan PS, Cheung KK, Berkowitz RS, Mok SC.SPARC (secreted protein acidic and rich in cysteine) induces apoptosis in ovarian cancer cells.Am J Pathol. 2001 Aug;159(2):609-22.
  • Lodge AJ, Anderson JJ, Ng SW, Fenwick F, Steward M, Haugk B, Horne CH, Angus B.Expression of topoisomerase IIIalpha in normal and neoplastic tissues determined by immunohistochemistry using a novel monoclonal antibody.Br J Cancer. 2000 Aug;83(4):498-505.
  • Ng SW, Yiu GK, Liu Y, Huang LW, Palnati M, Jun SH, Berkowitz RS, Mok SC.Analysis of p73 in human borderline and invasive ovarian tumor.Oncogene. 2000 Apr 6;19(15):1885-90.
  • Garrett AP, Ng SW, Muto MG, Welch WR, Bell DA, Berkowitz RS, Mok SC.ras gene activation and infrequent mutation in papillary serous carcinoma of the peritoneum.Gynecol Oncol. 2000 Apr;77(1):105-11.
  • Vegh GL,Fulop V,Liu Y,Ng SW,Tuncer ZS,Genest DR,Paldi-Haris P,Foldi J,Mok SC,Berkowitz RS.Differential gene expression pattern between normal human trophoblast and choriocarcinoma cell lines: downregulation of heat shock protein-27 in choriocarcinoma in vitro and in vivo.Gynecol Oncol. 1999 Dec;75(3):391-6.
  • Ng SW,Liu Y,Hasselblatt KT,Mok SC,Berkowitz RS.A new human topoisomerase III that interacts with SGS1 protein.Nucleic Acids Res. 1999 Feb 15;27(4):993-1000.
  • Fulop V,Colitti CV,Genest D,Berkowitz RS,Yiu GK,Ng SW,Szepesi J,Mok SC.DOC-2/hDab2, a candidate tumor suppressor gene involved in the development of gestational trophoblastic diseases.Oncogene. 1998 Jul 30;17(4):419-24.
  • Mok SC,Chan WY,Wong KK,Cheung KK,Lau CC,Ng SW,Baldini A,Colitti CV,Rock CO,Berkowitz RS.DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer.Oncogene. 1998 May 7;16(18):2381-7.
  • Ng SW, Liu Y, Schnipper LE.Cloning and characterization of the 5'-flanking sequence for the human DNA topoisomerase II beta gene.Gene. 1997 Dec 12;203(2):113-9.
  • Eder JP, Chan VT, Ng SW, Rizvi NA, Zacharoulis S, Teicher BA, Schnipper LE.DNA topoisomerase II alpha expression is associated with alkylating agent resistance.Cancer Res. 1995 Dec 15;55(24):6109-16.
  • Ng SW, Eder JP, Schnipper LE, Chan VT.Molecular cloning and characterization of the promoter for the Chinese hamster DNA topoisomerase II alpha gene.J Biol Chem. 1995 Oct 27;270(43):25850-8.
  • Chan VT, Ng SW, Eder JP, Schnipper LE.Molecular cloning and identification of a point mutation in the topoisomerase II cDNA from an etoposide-resistant Chinese hamster ovary cell line.J Biol Chem. 1993 Jan 25;268(3):2160-5.
  • Ng SW,Wiedemann M,Kontermann R,Petersen G.Molecular characterization of a putative peroxidase gene of Drosophila melanogaster.Biochim Biophys Acta. 1992 Dec 29;1171(2):224-8.