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Research Programs

Discipline-based Programs

Biostatistics and Computational Biology

Computational Biology

Computational Biology

The computational biologists in the Program conduct fundamental research in computational methods for the display and analysis of high-dimensional data in gene and protein expression, genetic abnormalities (such as loss of heterozygosity), and interacting networks of proteins. These biologists also build reusable tools for conducting genomic research.

The Computational Biology and Functional Genomic lab at the Dana-Farber Cancer Institute  focuses on the application of functional genomics techniques including microarrays, proteomics, metabolomics, and other high-throughput approaches. The lab also focuses on the development of computational approaches in support of these studies, helping to develop a comprehensive view of human diseases including cancer. The goals of the lab are to develop software, databases, and bioinformatics techniques that will allow development of new diagnostics and a more complete understanding of the cellular networks that are mechanistically responsible for diseases, and to make those tools widely and freely available to the research community.