• Home
  • News
  • Calendar
  • About DF/HCC
  • Membership
  • Visitor Center

Research Programs

Discipline-based Programs

Biostatistics and Computational Biology

Multicenter Studies



The Eastern Cooperative Oncology Group is a consortium of over 350 hospitals and smaller treatment centers in the United States, funded by the NCI to conduct multicenter clinical trials in adult malignancies. Now more than 50 years old, ECOG has a database of more than 100,000 cancer cases and is conducting active follow-up of over 20,000 patients treated in clinical trials.

Recent ECOG studies have shown that the addition of the anti-VEGF monoclonal antibody bevacizumab to standard chemotherapy improves outcomes in advanced colon, lung, and breast cancer. Other major studies have shown the benefits from rituximab therapy in non-Hodgkin’s lymphoma and from thalidomide in multiple myeloma. ECOG is also initiating new studies investigating use of molecular markers to tailor treatments for patients in breast and colorectal cancer.