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Research Programs

Discipline-based Programs

Outcomes Research

Collaborative Interactions

Collaborative Interactions

Examples of large projects that have grown directly out of DF/HCC-fostered collaborations include:

Cancer Care Outcomes Research and Surveillance Consortium (CanCORS)

This five-year, $40 million NCI-funded study is enrolling a population-based sample of 10,000 patients with newly diagnosed lung or colorectal cancer. The study has two primary goals:

  1. Examine processes of care with a special focus on why certain groups, including the elderly and minority patients, receive lower-quality care.
  2. Assess clinical and patient-reported outcomes during treatment and survivorship in order to better understand the process-outcome linkage for lung or colorectal cancers in the routine care setting.

Cancer Intervention and Surveillance Modeling Network (CISNET)

CISNET is a consortium of NCI-sponsored investigators whose focus is to use modeling to improve understanding of the impact of cancer control interventions (e.g., prevention, screening, and treatment) on population trends in incidence and mortality. These models are also used to project future trends and to help determine optimal cancer control strategies. The DF/HCC CISNET project is developing a specific policy model for the prevention, detection, and treatment of colorectal cancer in the United States.

The Lung Cancer Policy Model

The goal of this NCI-funded study is to develop a lung cancer model capable of guiding screening policy decisions over the next several years. Once the results of ongoing clinical trials are available, the model will also be used to translate short-term trial results into lifetime health and economic consequences. This project is a major collaboration among several DF/HCC programs, including Outcomes Research, Lung Cancer, Cancer Epidemiology, and Biostatistics.

Improving Cancer Care in Massachusetts (CAMA)

An example of a unique, collaborative project focused on translational research that has been made possible by the DF/HCC. Established projects include:

  • Tailored Information Project (TIP) 
  • Monitoring of cancer-care quality in real time
  • Shared health records for communication and coordination of care
  • Patient Perceptions of Quality of Care and Cancer Information

CAMA resulted from a strategic planning process to identify opportunities to bring together investigators who had not previously collaborated to conduct research that would not be possible under traditional funding mechanisms. It became clear that if the expertise and experience represented in the program could be brought to bear on the barriers to providing high-quality cancer care, unique approaches to long-standing problems might become possible.

CAMA’s goals include developing a better understanding of the main impediments to delivering consistently high-quality cancer care and developing a comprehensive intervention and research program to achieve two main goals:

  1. Improving the quality, comprehensiveness, and timeliness of data to assess cancer care
  2. Implementing system-wide changes to make cancer care more patient-centered and consistently higher quality for all patients, regardless of age, race, socioeconomic status, or location.