Here we provide an overview of data sources within the breast department, primarily from clinical trials and clinical databases. Descriptions of the studies and the databases are provided below. If you wish to use these data resources in your research, please refer to the tab on project proposals to submit an application to the Users Committee or OncDRS as appropriate.
Blood Sample Catalog
The Users Committee maintains a catalog of blood samples (whole blood, serum, plasma) collected from both industry-sponsored clinical trials (IST) and investigator-initiated/cohort studies within the breast oncology group. This information was compiled from CaTissue and the planned specimen collections and time points listed in the study protocols. We have also compiled the breast cancer sub-types, types of patients (i.e. menopausal or not), and setting (neoadjuvant, adjuvant, metastatic).
If you wish to use the archival blood samples for research questions, you may use this catalog to get a sense of what is available for your research question. If you wish to access the samples, we recommend the following:
- Reach out to the PI(s) of the relevant studies to evaluate whether a collaboration would be possible, the proposed question is feasible and of interest, and there is potentially sufficient leftover material for your proposed studies.
- If the PI is in agreement, submit a research proposal through the DFHCC Breast Users Committee. The study PI must be listed as a co-investigator on the users committee application.
- Whether or not your project will require submission of a separate IRB protocol will depend upon the exact language of the parent clinical trial consent form. The combination of the study PI and Users Committee chairs can guide you in navigating this question.
- If the proposal is approved by the Users Committee and once necessary IRB clearances are in place, you may then work with the Director of the Bank and/or his/her delegates to access the samples.