Activities:

1. Coordinate the review, preparation and activation of all clinical studies in the SPORE.

2. Support all active SPORE clinical studies through:
a. Recruitment and consent of patients to clinical studies
b. Management and follow-up of patients on clinical studies
c. Monitoring of accrual and toxicity, data management.

3. Obtain consent for data collection, banking of tissue and blood specimens, and permission to re-contact for cohort studies in women with breast cancer and those women at high risk of developing breast cancer.

The Core facilitates all SPORE-related clinical research across DFCI/BWH, BIDMC and MGH.  These institutions see over 4,000 new patients with breast cancer each year, and well over 10,000 patients are seen for ongoing therapy and or follow-up visits.  All SPORE investigators conducting clinical trials or other research studies involving human subjects will utilize the services of this Core. 

The Core works to minimize delays in the activation of protocols and to streamline patient recruitment and consent studies across multiple institutions.  With the complexity of this clinical environment, the Core will provide an overarching structure that eliminates the need to create individual project-based study teams in each of the participating institutions.

• To locate breast tissue, please create a query for the Viritual Specimen Locator.
• To order tissue, please complete this Breast Tissue Request Form.

Eric P. Winer, MD – DFCI
Harold J. Burstein, MD, PhD – DFCI
Steve Come, MD – BIDMC
Paula D. Ryan, MD, PhD – MGH
Mehra Golshan, MD – DFCI

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