Projects

Project 1: Biology and Treatment of BRCA1-Associated and Sporadic Basal-like Cancers
Co-Investigators: David Livingston, MD (DFCI) and Andrea Richardson, MD, PhD (BWH)

Project 2: Targeted Combinations for HER2-Positive Breast Cancer Biology
Co-Principal Investigators: Eric Winer, MD (DFCI); Thomas Roberts, MD (MGH); Randall King, MD, PhD (HMS); and Zoltan Szallasi, MD (CHB)

Project 3: Role of Coregulators in Response to Aromatase Inhibitors
Co-Principal Investigators: Steven Come, MD (BIDMC) and Myles Brown, MD (DFCI)

Project 5: The Role of Stromal Cells and Stromal-Epithelial Interaction in the Early Stages of Breast Tumor Progression: Implications for Risk, Prevention and Treatment
Co-Principal Investigators: Kornelia Polyak, MD, PhD (DFCI) and Stuart Schnitt, MD (BIDMC)

Project 6: Variation in Receptor Tyrosine Kinases and Breast Cancer Risk
Co-Principal Investigators: Joan Siefert Brugge, PhD (HMS); Alexander Miron, PhD (DFCI); Sue Hankinson, MPH, ScD (HSPH); and Stuart Schnitt, MD (BIDMC)

*Please note that Project 4 was terminated approximately two years ago.