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Project 1: Genetic analysis of non-small cell lung cancer survival
Project Co-Leaders: David Christiani, MD, MPH (HSPH), John Wain, MD (MGH), and Rebecca Suk Heist, MD, MPH (MGH)

Project 2: Foxa2 and C/EBP transcription factors in the pathogenesis and treatment of lung cancer
Project Co-Leaders: Daniel Tenen, MD (BIDMC), Daniel Costa, MD (BIDMC), and Balazs Halmos, MD (Case Western Reserve University)
Investigator: Susumu Kobayashi, MD, PhD (BIDMC)

Project 3: Targeting erlotinib-resistant lung cancer with rational combination treatments
Project Co-Leaders: Jeffrey Settleman, PhD (MGH) and Henning Willers, MD (MGH)
Consultants: Daniel Haber, MD, PhD (MGH) and Lecia Sequist, MD, MPH (MGH)

Project 4: Translational Studies of Hsp90 Inhibitors in NSCLC
Project Co-Leaders: Geoffrey Shapiro, MD, PhD (DFCI) and Kwok-Kin Wong, MD, PhD (DFCI)
Investigator: Lecia Sequist, MD, MPH (MGH)

Projet 5: Mechanisms of acquired resistance to epidermal growth factor receptor-targeted agents
Project Co-Leaders: Pasi Jšnne, MD, PhD (DFCI) and Jeffrey Engelman, MD, PhD (MGH)
Investigator: Lewis Cantley, PhD (BIDMC)