Ovarian SPORE

The Dana-Farber/Harvard SPORE in ovarian cancer (Ovarian SPORE) is focused on finding new ways to prevent, diagnose and treat ovarian cancer. Among DF/HCC projects cited below are studies to identify modifiable environmental risk factors associated with ovarian cancer and their interaction with the genotype, research to identify the molecular basis of carcinogenesis in ovarian cancer, and the design of novel immunotherapies to treat women with ovarian cancer. The Ovarian SPORE represents a significant collaboration that includes research investigators from all of the major DF/HCC sites.

Project 1: Modifiable Risk Factors and Gene/Environmental Interactions in Ovarian Cancer

Project 2: Genetic Alterations in Early Stage Epithelial Ovarian Tumors

Project 3: Identifying Novel Serum, Plasma and Urine Biomarkers of Occult Ovarian Cancer from High-Risk Women Undergoing Salpingo Oophorectomy

Project 4: Defining Clinical Response Genes and Protiens in High-Risk Epithelial Ovarian Carcinoma

Project 5: Novel Immunotherapeutic Approaches for Ovarian Cancer