Photo of Annekathryn Goodman,  MD

Annekathryn Goodman, MD

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 724-4800
Fax: (617) 724-6898

Annekathryn Goodman, MD

Massachusetts General Hospital


  • Professor, Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School
  • Assistant Director, Vincent Gynecologic Oncology Division, Massachusetts General Hospital


Research Abstract

HIV and cervical neoplasia

Novel surgeries in cervical cancer

Preservation of reproductive potential

Principal Investigator Gynecology Oncology Group

New pap smear applications


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  • St Laurent JD, Davis MR, Feltmate CM, Goodman A, Del Carmen MG, Horowitz NE, Lee SI, Growdon WB. Prognostic Value of Preoperative Imaging: Comparing 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography to Computed Tomography Alone for Preoperative Planning in High-risk Histology Endometrial Carcinoma. Am J Clin Oncol 2020; 43:714-719. PubMed
  • Goodman A. Deep-Learning-Based Evaluation of Dual Stain Cytology for Cervical Cancer Screening: A New Paradigm. Journal of the National Cancer Institute 2020. PubMed
  • Cramer DW, Benjamin Iv WJ, Vitonis AF, Berkowitz R, Goodman A, Matulonis U. Differential blood count as triage tool in evaluation of pelvic masses. Int J Gynecol Cancer 2020. PubMed
  • Alimena S, Scarpetti L, Blouch EL, Rodgers L, Shannon K, Del Carmen M, Goodman A, Growdon WB, Eisenhauer E, Sisodia RC. Factors associated with referral and completion of genetic counseling in women with epithelial ovarian cancer. Int J Gynecol Cancer 2020. PubMed
  • Manning-Geist BL, Alimena S, Del Carmen MG, Goodman A, Clark RM, Growdon WB, Horowitz NS, Berkowitz RS, Muto MG, Worley MJ. Infection, thrombosis, and oncologic outcome after interval debulking surgery: Does perioperative blood transfusion matter? Gynecol Oncol 2019; 153:63-67. PubMed
  • Pervin S, Ruma FI, Rahman K, Ferdous J, Ara R, Abu Syed MM, Goodman A. Adjuvant Hysterectomy in Patients With Residual Disease After Radiation for Locally Advanced Cervical Cancer: A Prospective Longitudinal Study. J Glob Oncol 2019; 5:1-7. PubMed
  • Yeh AC, Khan MA, Harlow J, Biswas AR, Akter M, Ferdous J, Ara T, Islam M, Caron M, Barron AM, Moran J, Brezina M, Nazneen H, Kamruzzaman M, Saha A, Marshall A, Afrose S, Stowell C, Preffer F, Bangsberg D, Goodman A, Attar E, McAfee S, Spitzer TR, Dey BR. Hematopoietic Stem-Cell Transplantation in the Resource-Limited Setting: Establishing the First Bone Marrow Transplantation Unit in Bangladesh. J Glob Oncol 2018. PubMed
  • Goodman A. Endometrial cancer in the elderly: does patient age influence the choice of treatment interventions and do age-related treatment choices impact survival? Menopause 2018. PubMed
  • Nitecki R, Diver EJ, Kamdar MM, Boruta DM, Del Carmen MC, Clark RM, Goodman A, Schorge JO, Growdon WB. Patterns of palliative care referral in ovarian cancer: A single institution 5 year retrospective analysis. Gynecol Oncol 2018; 148:521-526. PubMed
  • Melamed A, Manning-Geist B, Bregar AJ, Diver EJ, Goodman A, Del Carmen MG, Schorge JO, Rauh-Hain JA. Associations between residual disease and survival in epithelial ovarian cancer by histologic type. Gynecol Oncol 2017. PubMed
  • Melamed A, Nitecki R, Boruta DM, Del Carmen MG, Clark RM, Growdon WB, Goodman A, Schorge JO, Rauh-Hain JA. Laparoscopy Compared With Laparotomy for Debulking Ovarian Cancer After Neoadjuvant Chemotherapy. Obstet Gynecol 2017. PubMed
  • Tschernichovsky R, Goodman A. Risk-Reducing Strategies for Ovarian Cancer in BRCA Mutation Carriers: A Balancing Act. Oncologist 2017; 22:450-459. PubMed
  • Bigelow CA, Horowitz NS, Goodman A, Growdon WB, Del Carmen M, Kaimal AJ. Management and outcome of cervical cancer diagnosed in pregnancy. Am J Obstet Gynecol 2016. PubMed
  • Lax T, Dizon DS, Birrer M, Long A, Del Carmen M, Goodman A, Krasner C, Penson RT, Growdon W, Camargo CA, Banerji A. Extended carboplatin infusion does not reduce frequency of hypersensitivity reaction at initiation of retreatment in patients with recurrent platinum-sensitive ovarian cancer. J Allergy Clin Immunol Pract 2016. PubMed
  • Randall TC, Goodman A, Schmeler K, Durfee J, Pareja R, Munkarah A, Rulisa S, Ghebre R, Trimble EL, Chuang L. Cancer and the world's poor: What's a gynecologic cancer specialist to do? Gynecol Oncol 2016; 142:6-8. PubMed
  • Chuang LT, Randall TC, Denny L, Johnston CM, Schmeler KM, Covens AL, Cibula D, Bookman MA, Rawal S, DePetrillo D, Nam JH, Goodman A, Naik R, Manchanda R, Gaffney DK, Small W, Creutzberg C, Rattray C, Kesic V, Paraja R, Eiken M, Belleson K, Coleman RL, Barakat RR, Trimble EL, Quinn M. Sister Society Meeting on Global Education Development and Collaboration: Meeting Report. Int J Gynecol Cancer 2016; 26:1186-8. PubMed
  • Tschernichovsky R, Diver EJ, Schorge JO, Goodman A. The Role of Lymphadenectomy Versus Sentinel Lymph Node Biopsy in Early-stage Endometrial Cancer: A Review of the Literature. Am J Clin Oncol 2016. PubMed
  • Penson RT, Sales E, Sullivan L, Borger DR, Krasner CN, Goodman AK, Del Carmen MG, Growdon WB, Schorge JO, Boruta DM, Castro CM, Dizon DS, Birrer MJ. A SNaPshot of potentially personalized care: Molecular diagnostics in gynecologic cancer. Gynecol Oncol 2016; 141:108-12. PubMed
  • Pinder LF, Nelson BD, Eckardt M, Goodman A. A Public Health Priority: Disparities in Gynecologic Cancer Research for African-Born Women in the United States. Clin Med Insights Womens Health 2016; 9:21-6. PubMed
  • Hall T, Lee SI, Boruta DM, Goodman A. Medical Device Safety and Surgical Dissemination of Unrecognized Uterine Malignancy: Morcellation in Minimally Invasive Gynecologic Surgery. Oncologist 2015. PubMed
  • Melamed A, Rauh-Hain JA, Clemmer JT, Diver EJ, Hall TR, Clark RM, Uppal S, Goodman A, Boruta DM. Changing Trends in Lymphadenectomy for Endometrioid Adenocarcinoma of the Endometrium. Obstet Gynecol 2015; 126:815-22. PubMed
  • Joseph N, Clark RM, Dizon DS, Lee MS, Goodman A, Boruta D, Schorge JO, Del Carmen MG, Growdon WB. Delay in chemotherapy administration impacts survival in elderly patients with epithelial ovarian cancer. Gynecol Oncol 2015. PubMed
  • Aviki EM, Rauh-Hain JA, Clark RM, Hall TR, Berkowitz LR, Boruta DM, Growdon WB, Schorge JO, Goodman A. Gynecologic Oncologist as surgical consultant: intraoperative consultations during general gynecologic surgery as an important focus of gynecologic oncology training. Gynecol Oncol 2015; 137:93-7. PubMed
  • Clark RM, Lee MS, Alejandro Rauh-Hain J, Hall T, Boruta DM, del Carmen MG, Goodman A, Schorge JO, Growdon WB. Surgical Apgar Score and prediction of morbidity in women undergoing hysterectomy for malignancy. Gynecol Oncol 2015; 136:516-20. PubMed
  • Chuang L, Moore KN, Creasman WT, Goodman A, Henriquez Cooper H, Price FV, Conner MG, Gupta V, Gallion HH, Husseinzadeh N, Duarte J, Vu QH, Sanchez JA, Kanis MJ. Teaching gynecologic oncology in Low resource settings: a collaboration of health volunteers overseas and the society of gynecologic oncology. Gynecol Oncol 2014. PubMed
  • Lefkowits C, Sukumvanich P, Claxton R, Courtney-Brooks M, Kelley JL, McNeil MA, Goodman A. Needs assessment of palliative care education in gynecologic oncology fellowship: we're not teaching what we think is most important. Gynecol Oncol 2014. PubMed
  • Vargas R, Rauh-Hain JA, Clemmer J, Clark RM, Goodman A, Growdon WB, Schorge JO, Del Carmen MG, Horowitz NS, Boruta DM. Tumor size, depth of invasion, and histologic grade as prognostic factors of lymph node involvement in endometrial cancer: a SEER analysis. Gynecol Oncol 2014; 133:216-20. PubMed
  • Goodman A, Nour N. Cervical cancer screening: the complex interplay of medical infrastructure, society, and culture. Oncologist 2014; 19:315-7. PubMed
  • Foley OW, Rauh-Hain JA, Clark RM, Goodman A, Growdon WB, Boruta DM, Schorge JO, Del Carmen MG. Intraoperative Radiation Therapy in the Management of Gynecologic Malignancies. Am J Clin Oncol 2014. PubMed
  • Guseh SH, Rauh-Hain JA, Tambouret RH, Davis M, Clark RM, Boruta DM, Goodman A, Growdon WB, Schorge JO, del Carmen MG. Transitional cell carcinoma of the ovary: a case-control study. Gynecol Oncol 2014; 132:649-53. PubMed
  • Williams KA, Labidi-Galy SI, Terry KL, Vitonis AF, Welch WR, Goodman A, Cramer DW. Prognostic significance and predictors of the neutrophil-to-lymphocyte ratio in ovarian cancer. Gynecol Oncol 2014; 132:542-50. PubMed
  • Rauh-Hain JA, Vargas RJ, Clemmer J, Clark RM, Bradford LS, Growdon WB, Goodman A, Boruta DM, Schorge JO, Del Carmen MG. Mucinous Adenocarcinoma of the Endometrium Compared With Endometrioid Endometrial Cancer: A SEER Analysis. Am J Clin Oncol 2014. PubMed
  • Rauh-Hain JA, Clemmer J, Clark RM, Bradford LS, Growdon WB, Goodman A, Boruta DM, Schorge JO, del Carmen MG. Racial disparities and changes in clinical characteristics and survival for vulvar cancer over time. Am J Obstet Gynecol 2013; 209:468.e1-468.e10. PubMed
  • Rauh-Hain JA, Clemmer JT, Bradford LS, Clark RM, Growdon WB, Goodman A, Boruta DM, Schorge JO, del Carmen MG. Racial disparities in cervical cancer survival over time. Cancer 2013; 119:3644-52. PubMed
  • Penson RT, Goodman A, Growdon WB, Borger DR, Lee SI, Oliva E. Case records of the Massachusetts General Hospital. Case 14-2013. A 70-year-old woman with vaginal bleeding. N Engl J Med 2013; 368:1827-35. PubMed
  • Moulder JK, Garrett LA, Salazar GM, Goodman A. The role of radical surgery in the management of acquired uterine arteriovenous malformation. 2013; 6:303-10. PubMed
  • Diver E, O'Connor O, Garrett L, Boruta D, Goodman A, Del Carmen M, Schorge J, Mueller P, Growdon W. Modest benefit of total parenteral nutrition and chemotherapy after venting gastrostomy tube placement. Gynecol Oncol 2013; 129:332-5. PubMed
  • Bradford L, Goodman A. Cervical cancer screening and prevention in low-resource settings. Clin Obstet Gynecol 2013; 56:76-87. PubMed
  • Goodman A, Clark RM, Bradford LS. Caring for women with gynecologic cancers around the world: the need for global health training in gynecologic oncology fellowship programs. Am J Clin Oncol 2012; 35:511-3. PubMed
  • Honigberg MC, Bradford LS, Prabhakar AM, Hariri LP, Goodman A. Hypercalcemia associated with a malignant brenner tumor arising from a mature cystic teratoma. 2012; 5:592-600. PubMed
  • Bradford LS, Goodman A. Suffer little children. J Pastoral Care Counsel 2012; 66:10. PubMed
  • McCann CK, Growdon WB, Munro EG, Del Carmen MG, Boruta DM, Schorge JO, Goodman A. Prognostic significance of splenectomy as part of initial cytoreductive surgery in ovarian cancer. Ann Surg Oncol 2011. PubMed
  • Goodman A. Measuring success in ovarian cancer risk reducing strategies. Cancer 2011. PubMed
  • Rauh-Hain JA, Growdon WB, Rodriguez N, Goodman AK, Boruta DM, Schorge JO, Horowitz NS, del Carmen MG. Carcinosarcoma of the ovary: a case-control study. Gynecol Oncol 2011. PubMed
  • Cramer DW, Vitonis AF, Welch WR, Terry KL, Goodman A, Rueda BR, Berkowitz RS. Correlates of the preoperative level of CA125 at presentation of ovarian cancer. Gynecol Oncol 2010; 119:462-8. PubMed
  • Young RH, Goodman A, Penson RT, Russell AH, Uppot RN, Tambouret RH. Case records of the Massachusetts General Hospital. Case 8-2010. A 22-year-old woman with hypercalcemia and a pelvic mass. N Engl J Med 2010; 362:1031-40. PubMed
  • Sarosy GA, Hussain MM, Seiden MV, Fuller AF, Nikrui N, Goodman A, Minasian L, Reed E, Steinberg SM, Kohn EC. Ten-year follow-up of a phase 2 study of dose-intense paclitaxel with cisplatin and cyclophosphamide as initial therapy for poor-prognosis, advanced-stage epithelial ovarian cancer. Cancer 2010; 116:1476-84. PubMed
  • Xian W, Miron A, Roh M, Semmel DR, Yassin Y, Garber J, Oliva E, Goodman A, Mehra K, Berkowitz RS, Crum CP, Quade BJ. The Li-Fraumeni syndrome (LFS): a model for the initiation of p53 signatures in the distal Fallopian tube. J Pathol 2009; 220:17-23. PubMed
  • Mirabeau-Beale KL,Kornblith AB,Penson RT,Lee H,Goodman A,Campos SM,Duska L,Pereira L,Bryan J,Matulonis UA. Comparison of the quality of life of early and advanced stage ovarian cancer survivors. Gynecol Oncol 2009; 114:353-9. PubMed
  • Lu W, Matulonis UA, Doherty-Gilman A, Lee H, Dean-Clower E, Rosulek A, Gibson C, Goodman A, Davis RB, Buring JE, Wayne PM, Rosenthal DS, Penson RT. Acupuncture for chemotherapy-induced neutropenia in patients with gynecologic malignancies: a pilot randomized, sham-controlled clinical trial. J Altern Complement Med 2009; 15:745-53. PubMed
  • Goldstein MA,Goodman A,del Carmen MG,Wilbur DC. Case records of the Massachusetts General Hospital. Case 10-2009. A 23-year-old woman with an abnormal Papanicolaou smear. N Engl J Med 2009; 360:1337-44. PubMed
  • Olawaiye A,Del Carmen M,Tambouret R,Goodman A,Fuller A,Duska LR. Abdominal radical trachelectomy: Success and pitfalls in a general gynecologic oncology practice. Gynecol Oncol 2009; 112:506-10. PubMed
  • Olawaiye AB,Morgan JA,Goodman A,Fuller AF Jr,Penson RT. Epithelioid angiosarcoma of the uterus: a review of management. Arch Gynecol Obstet 2008; 278:401-4. PubMed
  • Olawaiye AB,Rauh-Hain JA,Withiam-Leitch M,Rueda B,Goodman A,del Carmen MG. Utility of pre-operative serum CA-125 in the management of uterine papillary serous carcinoma. Gynecol Oncol 2008; 110:293-8. PubMed
  • Olawaiye A, Withiam-Leitch M, Prabhakar H, Goodman A. An unusual presentation of endometrial cancer: a case report and literature review. Arch Gynecol Obstet 2008; 278:103-6. PubMed
  • Ko E,Lee S,Goodman A. Gemcitabine pulmonary toxicity in ovarian cancer. Oncologist 2008; 13:807-11. PubMed
  • Kornblith AB, Powell M, Regan MM, Bennett S, Krasner C, Moy B, Younger J, Goodman A, Berkowitz R, Winer E. Long-term psychosocial adjustment of older vs younger survivors of breast and endometrial cancer. Psychooncology 2007; 16:895-903. PubMed
  • Goodman A, Falzon M, Gelder C, George J. Central airway obstruction caused by a peripheral hamartoma. Lung Cancer 2007; 57:395-8. PubMed
  • Matulonis UA, Campos S, Duska L, Krasner CN, Atkinson T, Penson RT, Seiden MV, Verrill C, Fuller AF, Goodman A,. Phase I/II dose finding study of combination cisplatin and gemcitabine in patients with recurrent cervix cancer. Gynecol Oncol 2006; 103:160-4. PubMed
  • Rauh-Hain JA, Shoni M, Schorge JO, Goodman A, Horowitz NS, del Carmen MG. Prognostic determinants in patients with uterine and ovarian carcinosarcoma. J Reprod Med 2013; 58:297-304. PubMed
  • Garrett LA, Growdon WB, Goodman A, Boruta DM, Schorge JO, del Carmen MG. Endometriosis-associated ovarian malignancy: a retrospective analysis of presentation, treatment, and outcome. J Reprod Med 2014; 58:469-76. PubMed
  • Owusu-Darko S, Rauh-Hain JA, Horowitz NS, Goodman A, Schorge JO, Del Carmen MG. Comparison of outcomes in patients with early-stage mucinous endometrial cancer and those with endometrioid endometrial cancer, with and without adjuvant therapy. J Reprod Med 2015; 59:527-33. PubMed
  • Goodman A. Laparoscopy versus laparotomy in the surgical management of gynecologic disease in older women: a shifting paradigm. Menopause 2010; 17:19-20. PubMed
  • Rauh-Hain JA, Goodman A, Boruta DM, Schorge JO, Horowitz NS, del Carmen MG. Endometrial stromal sarcoma: a clinicopathologic study of 29 patients. J Reprod Med 2015; 59:547-52. PubMed