Photo of Daniel Faden,  MD

Daniel Faden, MD

Massachusetts General Hospital

Massachusetts General Hospital


dfaden@partners.org

Daniel Faden, MD

Massachusetts General Hospital

EDUCATIONAL TITLES

  • Instructor, Otology and Laryngology, Harvard Medical School
  • Instructor, Otolaryngology- Head and Neck Surgery, Harvard Medical School
  • Instructor, Otolaryngology- Head and Neck Surgery, Massachusetts Eye & Ear Infirmary
  • Instructor, Otolaryngology- Head and Neck Surgery, Massachusetts General Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

I am a head and neck oncologic surgeon and translational head and neck cancer investigator. My clinical practice focuses on the care of patients with advanced head and neck cancer and cranial base neoplasms, with a particular emphasis on minimally invasive techniques including transoral robotic surgery and endoscopic cranial base surgery. My research focuses on translational head and neck cancer genomics and biomarker discovery for surgical and therapeutic interventions with the aim of improving precision head and neck oncology decision making. To do so, I study how different cellular alterations, and infection by human papilloma virus, effect the behavior of head and neck cancers.

Publications

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  • Lavigne P, Faden D, Gardner PA, Fernandez-Miranda JC, Wang EW, Snyderman CH. Validation of training levels in endoscopic endonasal surgery of the skull base. Laryngoscope 2019. PubMed
  • Faden DL, Concha-Benavente F, Chakka AB, McMichael EL, Chandran U, Ferris RL. Immunogenomic correlates of response to cetuximab monotherapy in head and neck squamous cell carcinoma. Head Neck 2019. PubMed
  • Lavigne P, Faden DL, Wang EW, Snyderman CH. Complications of Nasoseptal Flap Reconstruction: A Systematic Review. J Neurol Surg B Skull Base 2018; 79:S291-S299. PubMed
  • Faden DL, Hughes MA, Lavigne P, Jankowitz BT, Wang EW, Fernandez-Miranda JC, Gardner PA, Snyderman CH. Diagnosis and endoscopic endonasal management of nontraumatic pseudoaneurysms of the cranial base. Int Forum Allergy Rhinol 2019; 8:641-647. PubMed
  • Faden DL, Asthana S, Tihan T, DeRisi J, Kliot M. Whole Exome Sequencing of Growing and Non-Growing Cutaneous Neurofibromas from a Single Patient with Neurofibromatosis Type 1. PLoS ONE 2018; 12:e0170348. PubMed
  • Faden DL, Thomas S, Cantalupo PG, Agrawal N, Myers J, DeRisi J. Multi-modality analysis supports APOBEC as a major source of mutations in head and neck squamous cell carcinoma. Oral Oncol 2019; 74:8-14. PubMed
  • Markey JD, Alemi AS, Naunheim ML, Faden DL, Heaton CM, Seth R. Spontaneous Iliopsoas Hematoma following Microvascular Free Tissue Transfer. Case Rep Otolaryngol 2019; 2017:7631673. PubMed
  • Faden DL, Arron ST, Heaton CM, DeRisi J, South AP, Wang SJ. Targeted next-generation sequencing of TP53 in oral tongue carcinoma from non-smokers. 2018; 45:47. PubMed
  • Alemi AS, Faden DL. Otolaryngologic Manifestations of Levamisole-Induced Vasculitis. JAMA Otolaryngol Head Neck Surg 2016; 142:299-300. PubMed
  • Li R, Faden DL, Fakhry C, Langelier C, Jiao Y, Wang Y, Wilkerson MD, Pedamallu CS, Old M, Lang J, Loyo M, Ahn SM, Tan M, Gooi Z, Chan J, Richmon J, Wood LD, Hruban RH, Bishop J, Westra WH, Chung CH, Califano J, Gourin CG, Bettegowda C, Meyerson M, Papadopoulos N, Kinzler KW, Vogelstein B, DeRisi JL, Koch WM, Agrawal N. Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke. Head Neck 2015. PubMed
  • Faden DL, Algazi A. Durable treatment of ameloblastoma with single agent BRAFi J Natl Cancer Inst 2017.
  • Fadel DL, Gomez R, Alvarado D, Duvvuri U.. Genomic Correlates of Exceptional Response to ErbB3 inhibition in head and neck squamous cell carcinoma. J Clin Oncol 2019.
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