Photo of Eleni Rettig,  MD

Eleni Rettig, MD

Brigham And Women's Hospital

Brigham And Women's Hospital

Eleni Rettig, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Instructor, Otology and Laryngology, Harvard Medical School
  • Associate Surgeon, Otolaryngology-Head and Neck Surgery, Brigham And Women's Hospital
  • Associate Surgeon, Head and Neck Cancer Treatment Center, Dana-Farber Cancer Institute

DF/HCC PROGRAM AFFILIATION

Research Abstract

I am a head and neck cancer surgeon with research interests in human papillomavirus-positive oropharynx cancers including epidemiology, natural history, screening, risk stratification, and surveillance; as well as other epidemiologic and clinical aspects of head and neck cancer. I trained in epidemiologic and clinical research methods during a two-year T32 research training fellowship that I completed as part of my surgical residency. My clinical activity includes the surgical treatment of head and neck tumors, transoral robotic surgery for oropharynx tumors, and microvascular reconstruction of the head and neck. I am involved in the clinical education of the Harvard Otolaryngology-Head and Neck Surgery residents.

Publications from Harvard Catalyst Profiles

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  • Mokhtari TE, Warinner C, Edwards H, Chan AW, Annino D, Schoenfeld JD, Sethi RKV, Rettig EM. Unusual presentation of HPV-positive squamous cell carcinoma of the nasolacrimal duct as carcinoma of unknown primary. Am J Otolaryngol 2022; 43:103457. PubMed
  • Arbab M, Chen YH, Tishler RB, Gunasti L, Glass J, Fugazzotto JA, Killoran JH, Sethi R, Rettig E, Annino D, Goguen L, Uppaluri R, Hsu C, Burke E, Hanna GJ, Lorch J, Haddad RI, Margalit DN, Schoenfeld JD. Association between radiation dose to organs at risk and acute patient reported outcome during radiation treatment for head and neck cancers. Head Neck 2022. PubMed
  • Rettig EM, Faden DL, Sandhu S, Wong K, Faquin WC, Warinner C, Stephens P, Kumar S, Kuperwasser C, Richmon JD, Uppaluri R, Varvares M, Sethi R, Hanna GJ, Sroussi H. Detection of circulating tumor human papillomavirus DNA before diagnosis of HPV-positive head and neck cancer. Int. J. Cancer 2022. PubMed
  • Hanna GJ, ONeill A, Shin KY, Wong K, Jo VY, Quinn CT, Cutler JM, Flynn M, Lizotte PH, Annino DJ, Goguen LA, Kass JI, Rettig EM, Sethi RKV, Lorch JH, Schoenfeld JD, Margalit DN, Tishler RB, Everett PC, Desai AM, Cavanaugh ME, Paweletz CP, Egloff AM, Uppaluri R, Haddad RI. Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck. Clin Cancer Res 2021. PubMed
  • Warinner CB, Bergmark RW, Sethi R, Rettig EM. Cancer-Related Activity Limitations Among Head and Neck Cancer Survivors. Laryngoscope 2021. PubMed
  • Windon MJ, Fakhry C, Margalit DN, Dey T, Rettig EM. Epidemiologic distinctions between base of tongue and tonsil oropharyngeal carcinomas. Head Neck 2021. PubMed
  • Rettig EM, Sethi RKV. Cancer of the Oropharynx and the Association with Human Papillomavirus. Hematol Oncol Clin North Am 2021. PubMed
  • Miller AL, Holcomb AJ, Parikh AS, Richards JM, Rathi VK, Goldfarb JW, Remenschneider AK, Bergmark RW, Annino DJ, Goguen LA, Rettig EM, Deschler DG, Emerick KS, Lin DT, Richmon JD, Chan CL, Min LC, Uppaluri R, Varvares MA. Assessment of Preoperative Functional Status Prior to Major Head and Neck Surgery: A Pilot Study. 2021. PubMed
  • Hanna GJ, Rettig EM, Park JC, Varvares MA, Lorch JH, Margalit DN, Schoenfeld JD, Tishler RB, Goguen LA, Annino DJ, Haddad RI, Uppaluri R. Hospitalization rates and 30-day all-cause mortality among head and neck cancer patients and survivors with COVID-19. Oral Oncol 2021; 112:105087. PubMed
  • Faraji F, Rettig EM, Tsai HL, El Asmar M, Fung N, Eisele DW, Fakhry C. The prevalence of human papillomavirus in oropharyngeal cancer is increasing regardless of sex or race, and the influence of sex and race on survival is modified by human papillomavirus tumor status. Cancer 2019; 125:761-769. PubMed
  • Rettig EM, Fakhry C, Khararjian A, Westra WH. Age Profile of Patients With Oropharyngeal Squamous Cell Carcinoma. JAMA Otolaryngol Head Neck Surg 2018; 144:538-539. PubMed
  • Windon MJ, D'Souza G, Rettig EM, Westra WH, van Zante A, Wang SJ, Ryan WR, Mydlarz WK, Ha PK, Miles BA, Koch W, Gourin C, Eisele DW, Fakhry C. Increasing prevalence of human papillomavirus-positive oropharyngeal cancers among older adults. Cancer 2018; 124:2993-2999. PubMed
  • Rettig EM, Zaidi M, Faraji F, Eisele DW, El Asmar M, Fung N, D'Souza G, Fakhry C. Oropharyngeal cancer is no longer a disease of younger patients and the prognostic advantage of Human Papillomavirus is attenuated among older patients: Analysis of the National Cancer Database. Oral Oncol 2018; 83:147-153. PubMed
  • D'Souza G, Westra WH, Wang SJ, van Zante A, Wentz A, Kluz N, Rettig E, Ryan WR, Ha PK, Kang H, Bishop J, Quon H, Kiess AP, Richmon JD, Eisele DW, Fakhry C. Differences in the Prevalence of Human Papillomavirus (HPV) in Head and Neck Squamous Cell Cancers by Sex, Race, Anatomic Tumor Site, and HPV Detection Method. JAMA Oncol 2017; 3:169-177. PubMed
  • Rettig EM, D'Souza G, Thompson CB, Koch WM, Eisele DW, Fakhry C. Health-related quality of life before and after head and neck squamous cell carcinoma: Analysis of the Surveillance, Epidemiology, and End Results-Medicare Health Outcomes Survey linkage. Cancer 2016; 122:1861-70. PubMed
  • Rettig EM, Wentz A, Posner MR, Gross ND, Haddad RI, Gillison ML, Fakhry C, Quon H, Sikora AG, Stott WJ, Lorch JH, Gourin CG, Guo Y, Xiao W, Miles BA, Richmon JD, Andersen PE, Misiukiewicz KJ, Chung CH, Gerber JE, Rajan SD, D'Souza G. Prognostic Implication of Persistent Human Papillomavirus Type 16 DNA Detection in Oral Rinses for Human Papillomavirus-Related Oropharyngeal Carcinoma. JAMA Oncol 2015; 1:907-15. PubMed
  • Wang Y, Springer S, Mulvey CL, Silliman N, Schaefer J, Sausen M, James N, Rettig EM, Guo T, Pickering CR, Bishop JA, Chung CH, Califano JA, Eisele DW, Fakhry C, Gourin CG, Ha PK, Kang H, Kiess A, Koch WM, Myers JN, Quon H, Richmon JD, Sidransky D, Tufano RP, Westra WH, Bettegowda C, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Agrawal N. Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas. Sci Transl Med 2015; 7:293ra104. PubMed
  • Rettig E, Kiess AP, Fakhry C. The role of sexual behavior in head and neck cancer: implications for prevention and therapy. Expert Rev Anticancer Ther 2015; 15:35-49. PubMed
  • Warinner CB, Hayirli TC, Bergmark RW, Sethi R, Rettig EM. Patterns of Technology Use Among Patients With Head and Neck Cancer and Implications for Telehealth. OTO Open ; 5:2473974X211018612. PubMed
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