Photo of Guillermo J. Tearney,  MD, PhD

Guillermo J. Tearney, MD, PhD

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 724-2979
Fax: (617) 726-4103


gtearney@partners.org

Guillermo J. Tearney, MD, PhD

Massachusetts General Hospital

EDUCATIONAL TITLES

  • Professor, Pathology, Harvard Medical School
  • Pathologist, Pathology, Massachusetts General Hospital

DF/HCC PROGRAM AFFILIATION

DF/HCC ASSOCIATIONS

  • Member, Center Scientific Council

Research Abstract

My research involves developing and validating high-tech devices for screening for early cancers of the gastrointestinal tract. These devices include a variety of different endomicroscopy technologies, including swallowable capsules for conducting microscopy of the entire alimentary tract.

Publications

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  • Mathur SC, Fitzmaurice M, Reder NP, Krishnamurthy S, Kennedy M, Tearney GJ, Shevchuk-Chaban MM. Development of Functional Requirements for Ex Vivo Pathology Applications of In Vivo Microscopy System: A Proposal From the In Vivo Microscopy Committee of the College of American Pathologists. Arch Pathol Lab Med 2019. PubMed
  • Kang D, Do D, Ryu J, Grant CN, Giddings SL, Rosenberg M, Hesterberg PE, Yuan Q, Garber JJ, Katz AJ, Tearney GJ. A miniaturized, tethered, spectrally-encoded confocal endomicroscopy capsule. Lasers Surg Med 2019. PubMed
  • Gardecki JA, Singh K, Wu CL, Tearney GJ. Imaging the Human Prostate Gland Using 1-μm-Resolution Optical Coherence Tomography. Arch Pathol Lab Med 2018. PubMed
  • Wells WA, Harhen MT, Thrall MJ, Shevchuk MM, Tearney GJ, Hariri LP. In Vivo and Ex Vivo Microscopy: A Business Plan to Justify the Introduction of Similar Emerging Technologies Into Pathology Practice. Arch Pathol Lab Med 2018. PubMed
  • Wells WA, Thrall M, Sorokina A, Fine J, Krishnamurthy S, Haroon A, Rao B, Shevchuk MM, Wolfsen HC, Tearney GJ, Hariri LP. In Vivo and Ex Vivo Microscopy: Moving Toward the Integration of Optical Imaging Technologies Into Pathology Practice. Arch Pathol Lab Med 2018. PubMed
  • Tao W, Ji X, Zhu X, Li L, Wang J, Zhang Y, Saw PE, Li W, Kong N, Islam MA, Gan T, Zeng X, Zhang H, Mahmoudi M, Tearney GJ, Farokhzad OC. Two-Dimensional Antimonene-Based Photonic Nanomedicine for Cancer Theranostics. Adv. Mater. Weinheim 2018; 30:e1802061. PubMed
  • Montoro DT, Haber AL, Biton M, Vinarsky V, Lin B, Birket SE, Yuan F, Chen S, Leung HM, Villoria J, Rogel N, Burgin G, Tsankov AM, Waghray A, Slyper M, Waldman J, Nguyen L, Dionne D, Rozenblatt-Rosen O, Tata PR, Mou H, Shivaraju M, Bihler H, Mense M, Tearney GJ, Rowe SM, Engelhardt JF, Regev A, Rajagopal J. A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. Nature 2018. PubMed
  • Gora MJ, Quénéhervé L, Carruth RW, Lu W, Rosenberg M, Sauk JS, Fasano A, Lauwers GY, Nishioka NS, Tearney GJ. Tethered capsule endomicroscopy for unsedated microscopic imaging of the esophagus, stomach, and duodenum in humans (with video). Gastrointest Endosc 2018. PubMed
  • Ikuta M, Kang D, Do D, Zeidan A, Tearney GJ. Single-beam spectrally encoded color imaging. Opt Lett 2018; 43:2229-2232. PubMed
  • Trindade AJ, Inamdar S, Smith MS, Rosen L, Han D, Chang KJ, Leggett CL, Lightdale CJ, Pleskow DK, Sejpal DV, Tearney GJ, Thomas RM, Wallace MB. Learning curve and competence for volumetric laser endomicroscopy in Barrett's esophagus using cumulative sum analysis. Endoscopy 2018; 50:471-478. PubMed
  • Trindade AJ, Inamdar S, Smith MS, Rosen L, Han D, Chang KJ, Leggett CL, Lightdale CJ, Pleskow DK, Sejpal DV, Tearney GJ, Thomas RM, Wallace MB. Correction: Learning curve and competence for volumetric laser endomicroscopy in Barrett's esophagus using cumulative sum analysis. Endoscopy 2018; 50:C10. PubMed
  • Freeman EE, Semeere A, Osman H, Peterson G, Rajadhyaksha M, González S, Martin JN, Anderson RR, Tearney GJ, Kang D. Smartphone confocal microscopy for imaging cellular structures in human skin . Biomed Opt Express 2018; 9:1906-1915. PubMed
  • Tabatabaei N, Kang D, Kim M, Wu T, Grant CN, Rosenberg M, Nishioka NS, Hesterberg PE, Garber J, Yuan Q, Katz AJ, Tearney GJ. Clinical Translation of Tethered Confocal Microscopy Capsule for Unsedated Diagnosis of Eosinophilic Esophagitis. Sci Rep 2018; 8:2631. PubMed
  • Yin B, Hyun C, Gardecki JA, Tearney GJ. Extended depth of focus for coherence-based cellular imaging. Optica 2018; 4:959-965. PubMed
  • Trindade AJ, Inamdar S, Smith MS, Chang KJ, Leggett CL, Lightdale CJ, Pleskow DK, Sejpal DV, Tearney GJ, Thomas RM, Wallace MB. Volumetric laser endomicroscopy in Barrett's esophagus: interobserver agreement for interpretation of Barrett's esophagus and associated neoplasia among high-frequency users. Gastrointest Endosc 2018; 86:133-139. PubMed
  • Swager AF, Tearney GJ, Leggett CL, van Oijen MGH, Meijer SL, Weusten BL, Curvers WL, Bergman JJGHM. Identification of volumetric laser endomicroscopy features predictive for early neoplasia in Barrett's esophagus using high-quality histological correlation. Gastrointest Endosc 2018; 85:918-926.e7. PubMed
  • Chu KK, Kusek ME, Liu L, Som A, Yonker LM, Leung H, Cui D, Ryu J, Eaton AD, Tearney GJ, Hurley BP. Illuminating dynamic neutrophil trans-epithelial migration with micro-optical coherence tomography. Sci Rep 2018; 8:45789. PubMed
  • Kang D, Schlachter SC, Carruth RW, Kim M, Wu T, Tabatabaei N, Soomro AR, Grant CN, Rosenberg M, Nishioka NS, Tearney GJ. Large-area spectrally encoded confocal endomicroscopy of the human esophagus in vivo. Lasers Surg Med 2018; 49:233-239. PubMed
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