Photo of Karen Jean C. Marcus, MD

Karen Jean C. Marcus, MD

Boston Children's Hospital

Boston Children's Hospital
Phone: (617) 355-8399
Fax: (617) 730-0211


kmarcus@lroc.harvard.edu

Photo of Karen Jean C. Marcus, MD

Boston Children's Hospital
Phone: (617) 355-8399
Fax: (617) 730-0211


kmarcus@lroc.harvard.edu

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Karen Jean C. Marcus, MD

Boston Children's Hospital

EDUCATIONAL TITLES

  • Associate Professor, Radiation Oncology, Harvard Medical School
  • Division Chief, Radiation Oncology, Boston Children's Hospital
  • Staff Radiation Oncologist, Radiation Oncology, Dana-Farber Cancer Institute

DF/HCC PROGRAM AFFILIATION

Research Abstract

My primary interest is in pediatric malignancies. As a pediatric radiation oncologist, I am involved in the treatment of many pediatric malignancies including but not limitied to rhabdomyosarcmoa, Ewing sarcoma, soft tissue sarcomas, neuroblastoma, renal tumors and brain tumors as well as lymphoma and leukemias. Another important area of focus is radiotherapy for palliation in advanced childhood cancer

Publications from Harvard Catalyst Profiles

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  • Ahmed SK, Witten BG, Harmsen WS, Rose PS, Krailo M, Marcus KJ, Randall RL, DuBois SG, Janeway KA, Womer RB, Grier HE, Gorlick RG, Laack NNI. Analysis of local control outcomes and clinical prognostic factors in localized pelvic Ewing sarcoma patients treated with radiation therapy: A Report from the Children's Oncology Group. Int J Radiat Oncol Biol Phys 2022. PubMed
  • Liu KX, Poux N, Shin KY, Moore N, Chen YH, Margossian S, Whangbo JS, Duncan CN, Lehmann LE, Marcus KJ. Comparison of Pulmonary Toxicity after Total Body Irradiation- and Busulfan-Based Myeloablative Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients. Transplant Cell Ther 2022. PubMed
  • Liu KX, Shang HH, Cacciotti C, Everdell E, Aizer AA, Rahman R, Malinowski S, Meredith DM, Kamihara J, Wen PY, Ligon KL, Chi SN, Marcus KJ, Yeo KK, Alexandrescu S, Haas-Kogan DA. DICER1 mutations in primary central nervous system tumors: new insights into histologies, mutations, and prognosis. J. Neurooncol. 2022. PubMed
  • Howard TP, Boyle PJ, Marcus KJ, Haas-Kogan DA, Liu KX. Clinical outcomes for pediatric patients receiving radiotherapy for solid tumor central nervous system metastases. Pediatr Blood Cancer 2021; 68:e29331. PubMed
  • Ahmed S, Bossenberger T, Nalichowski A, Bredfeldt JS, Bartlett S, Bertone K, Dominello M, Dziemianowicz M, Komajda M, Makrigiorgos GM, Marcus KJ, Ng A, Thomas M, Burmeister J. A bi-institutional multi-disciplinary failure mode and effects analysis (FMEA) for a Co-60 based total body irradiation technique. Radiat Oncol 2021; 16:224. PubMed
  • Fouda MA, Day EL, Zurakowski D, Scott RM, Smith ER, Marcus KJ, Fehnel KP. Predictors of progression in radiation-induced versus nonradiation-induced pediatric meningiomas: a large single-institution surgical experience. J Neurosurg Pediatrics 2021. PubMed
  • Shen CJ, Perkins SM, Bradley JA, Mahajan A, Marcus KJ. Radiation therapy for infants with cancer. Pediatr Blood Cancer 2021; 68 Suppl 2:e28700. PubMed
  • Chang JH, Poppe MM, Hua CH, Marcus KJ, Esiashvili N. Acute lymphoblastic leukemia. Pediatr Blood Cancer 2021; 68 Suppl 2:e28371. PubMed
  • Tsang DS, Vargo JA, Goddard K, Breneman JC, Kalapurakal JA, Marcus KJ. Palliative radiation therapy for children with cancer. Pediatr Blood Cancer 2021; 68 Suppl 2:e28292. PubMed
  • Constine LS, Olch AJ, Jackson A, Hua CH, Ronckers CM, Milano MT, Marcus KJ, Yorke E, Hodgson DC, Howell RM, Hudson MM, Williams JP, Marples B, C M Kremer L, Marks LB, Bentzen SM. Pediatric Normal Tissue Effects in the Clinic (PENTEC): An International Collaboration to Assess Normal Tissue Radiation Dose-Volume-Response Relationships for Children With Cancer. Int J Radiat Oncol Biol Phys 2021. PubMed
  • Fouda MA, Karsten M, Staffa SJ, Scott RM, Marcus KJ, Baird LC. Management strategies for recurrent pediatric craniopharyngioma: new recommendations. J Neurosurg Pediatrics 2021. PubMed
  • Liu KX, Ioakeim-Ioannidou M, Susko MS, Rao AD, Yeap BY, Snijders AM, Ladra MM, Vogel J, Zaslowe-Dude C, Marcus KJ, Yock TI, Grassberger C, Braunstein SE, Haas-Kogan DA, Terezakis SA, MacDonald SM. A Multi-institutional Comparative Analysis of Proton and Photon Therapy-Induced Hematologic Toxicity in Patients With Medulloblastoma. Int J Radiat Oncol Biol Phys 2021; 109:726-735. PubMed
  • Fouda MA, Day EL, Staffa SJ, Scott RM, Marcus KJ, Baird LC. Postoperative MR imaging surveillance of pediatric craniopharyngioma: new institutional guidelines. 2021; 37:853-861. PubMed
  • Tsai JW, Manoharan N, Alexandrescu S, Zimmerman MA, Scully J, Chordas C, Clymer J, Wright KD, Filbin M, Ullrich NJ, Marcus KJ, Haas-Kogan D, Chi SN, Bandopadhayay P, Yeo KK. Outcomes after first relapse of childhood intracranial ependymoma. Pediatr Blood Cancer 2021. PubMed
  • Dombrowski ND, Wolter NE, Robson CD, Kawai K, Irace AL, Vargas SO, Marcus KJ, Mack JW, Collins NB, Rahbar R. Role of Surgery in Rhabdomyosarcoma of the Head and Neck in Children. Laryngoscope 2021; 131:E984-E992. PubMed
  • Kalapurakal JA, Breneman JC, Janssens GO, Marcus K. Introduction to the COG/SIOP/PROS supplement on radiation oncology. Pediatr Blood Cancer 2020. PubMed
  • Fouda MA, Zurakowski D, Scott RM, Marcus KJ, Manley PE, Ullrich NJ, Cohen LE, Goumnerova LC. Novel predictive scoring system for morbid hypothalamic obesity in patients with pediatric craniopharyngioma. 2020. PubMed
  • Paulino AC, Dieckmann K, Esiashvili N, Mahajan A, Janssens GO, Halperin EC, Carrie C, Parkes J, Wolden SL, Seiersen K, Awrey S, Dieter-Kortmann R, Marcus KJ. Training and education of pediatric radiation oncologists: A survey from the 2019 Pediatric Radiation Oncology Society meeting. Pediatr Blood Cancer 2020. PubMed
  • Hua CH, Vern-Gross TZ, Hess CB, Olch AJ, Alaei P, Sathiaseelan V, Deng J, Ulin K, Laurie F, Gopalakrishnan M, Esiashvili N, Wolden SL, Krasin MJ, Merchant TE, Donaldson SS, FitzGerald TJ, Constine LS, Hodgson DC, Haas-Kogan DA, Mahajan A, Laack NN, Marcus KJ, Taylor PA, Ahern VA, Followill DS, Buchsbaum JC, Breneman JC, Kalapurakal JA. Practice patterns and recommendations for pediatric image-guided radiotherapy: A Children's Oncology Group report. Pediatr Blood Cancer 2020. PubMed
  • Liu KX, Collins NB, Greenzang KA, Furutani E, Campbell K, Groves A, Mullen EA, Shusterman S, Spidle J, Marcus KJ, Weil BR, Weldon CB, Frazier AL, Janeway KA, O'Neill AF, Mack JW, DuBois SG, Shulman DS. The use of interval-compressed chemotherapy with the addition of vincristine, irinotecan, and temozolomide for pediatric patients with newly diagnosed desmoplastic small round cell tumor. Pediatr Blood Cancer 2020. PubMed
  • Atun R, Bhakta N, Denburg A, Frazier AL, Friedrich P, Gupta S, Lam CG, Ward ZJ, Yeh JM, Allemani C, Coleman MP, Di Carlo V, Loucaides E, Fitchett E, Girardi F, Horton SE, Bray F, Steliarova-Foucher E, Sullivan R, Aitken JF, Banavali S, Binagwaho A, Alcasabas P, Antillon F, Arora RS, Barr RD, Bouffet E, Challinor J, Fuentes-Alabi S, Gross T, Hagander L, Hoffman RI, Herrera C, Kutluk T, Marcus KJ, Moreira C, Pritchard-Jones K, Ramirez O, Renner L, Robison LL, Shalkow J, Sung L, Yeoh A, Rodriguez-Galindo C. Sustainable care for children with cancer: a Lancet Oncology Commission. Lancet Oncol. 2020; 21:e185-e224. PubMed
  • Lee BK, Boyle PJ, Zaslowe-Dude C, Wolfe J, Marcus KJ. Palliative radiotherapy for pediatric patients: Parental perceptions of indication, intent, and outcomes. Pediatr Blood Cancer 2020; 67:e28003. PubMed
  • Sullivan M, Bouffet E, Rodriguez-Galindo C, Luna-Fineman S, Khan MS, Kearns P, Hawkins DS, Challinor J, Morrissey L, Fuchs J, Marcus K, Balduzzi A, Basset-Salom L, Caniza M, Baker JN, Kebudi R, Hessissen L, Sullivan R, Pritchard-Jones K. The COVID-19 pandemic: A rapid global response for children with cancer from SIOP, COG, SIOP-E, SIOP-PODC, IPSO, PROS, CCI, and St Jude Global. Pediatr Blood Cancer 2020; 67:e28409. PubMed
  • Bitterman DS, MacDonald SM, Yock TI, Tarbell NJ, Wright KD, Chi SN, Marcus KJ, Haas-Kogan DA. Revisiting the Role of Radiation Therapy for Pediatric Low-Grade Glioma. J Clin Oncol 2019. PubMed
  • Devine CA, Liu KX, Ioakeim-Ioannidou M, Susko M, Poussaint TY, Huisman TAGM, Aboian M, Brown D, Zaslowe-Dude C, Rao AD, Orlina LT, Rawal B, Mueller S, Marcus KJ, Terezakis SA, Braunstein SE, Haas-Kogan DA. Brainstem injury in pediatric patients receiving posterior fossa photon radiation. Int J Radiat Oncol Biol Phys 2019. PubMed
  • Fouda MA, Scott RM, Marcus KJ, Ullrich N, Manley PE, Kieran MW, Goumnerova LC. Sixty years single institutional experience with pediatric craniopharyngioma: between the past and the future. 2019. PubMed
  • Ludmir EB, Mahajan A, Ahern V, Ajithkumar T, Alapetite C, Bernier-Chastagner V, Bindra RS, Bishop AJ, Bolle S, Brown PD, Carrie C, Chalmers AJ, Chang EL, Chung C, Dieckmann K, Esiashvili N, Gandola L, Ghia AJ, Gondi V, Grosshans DR, Harrabi SB, Horan G, Indelicato DJ, Jalali R, Janssens GO, Krause M, Laack NN, Laperriere N, Laprie A, Li J, Marcus KJ, McGovern SL, Merchant TE, Merrell KW, Padovani L, Parkes J, Paulino AC, Schwarz R, Shih HA, Souhami L, Sulman EP, Taylor RE, Thorp N, Timmermann B, Wheeler G, Wolden SL, Woodhouse KD, Yeboa DN, Yock TI, Kortmann RD, McAleer MF. Assembling the brain trust: the multidisciplinary imperative in neuro-oncology. Nat Rev Clin Oncol 2019. PubMed
  • Dombrowski ND, Wolter NE, Irace AL, Cunningham MJ, Mack JW, Marcus KJ, Vargas SO, Perez-Atayde AR, Robson CD, Rahbar R. Mucoepidermoid carcinoma of the head and neck in children. Int. J. Pediatr. Otorhinolaryngol. 2019; 120:93-99. PubMed
  • Kieran MW, Goumnerova L, Manley P, Chi SN, Marcus KJ, Manzanera AG, Polanco MLS, Guzik BW, Aguilar-Cordova E, Diaz-Montero CM, DiPatri AJ, Tomita T, Lulla R, Greenspan L, Aguilar LK, Goldman S. Phase I study of gene-mediated cytotoxic immunotherapy with AdV-tk as adjuvant to surgery and radiation for pediatric malignant glioma and recurrent ependymoma. 2019; 21:537-546. PubMed
  • Hwang WL, Wolfson RL, Niemierko A, Marcus KJ, DuBois SG, Haas-Kogan D. Clinical Impact of Tumor Mutational Burden in Neuroblastoma. Journal of the National Cancer Institute 2018. PubMed
  • Kalapurakal JA, Gopalakrishnan M, Walterhouse DO, Rigsby CK, Rademaker A, Helenowski I, Kessel S, Morano K, Laurie F, Ulin K, Esiashvili N, Katzenstein H, Marcus K, Followill D, Wolden SL, Mahajan A, Fitzgerald TJ. Cardiac-sparing whole lung imrt in patients with pediatric tumors and lung metastasis: Final report of a prospective multicenter clinical trial. Int J Radiat Oncol Biol Phys 2018. PubMed
  • Breneman JC, Donaldson SS, Constine L, Merchant T, Marcus K, Paulino AC, Followill D, Mahajan A, Laack N, Esiashvili N, Haas-Kogan D, Laurie F, Olch A, Ulin K, Hodgson D, Yock TI, Terezakis S, Krasin M, Panoff J, Chuba P, Hua CH, Hess CB, Houghton PJ, Wolden S, Buchsbaum J, Fitzgerald TJ, Kalapurakal JA. The Children's Oncology Group Radiation Oncology Discipline: 15 Years of Contributions to the Treatment of Childhood Cancer. Int J Radiat Oncol Biol Phys 2018; 101:860-874. PubMed
  • Ozuah NW, Marcus KJ, LaCasce AS, Billett AL. Excellent Outcomes Following Response-based Omission of Radiotherapy in Children and Adolescents With Intermediate or High-risk Hodgkin Lymphoma. J. Pediatr. Hematol. Oncol. 2017. PubMed
  • Patel CG, Michaelson E, Chen YH, Silver B, Marcus KJ, Stevenson MA, Mauch PM, Ng AK. Reduced Mortality Risk in the Recent Era in Early-Stage Hodgkin Lymphoma Patients Treated With Radiation Therapy With or Without Chemotherapy. Int J Radiat Oncol Biol Phys 2017. PubMed
  • Mak KS, Lee SW, Balboni TA, Marcus KJ. Clinical outcomes and toxicity following palliative radiotherapy for childhood cancers. Pediatr Blood Cancer 2017. PubMed
  • Ahmed SK, Randall RL, DuBois SG, Harmsen WS, Krailo M, Marcus KJ, Janeway KA, Geller DS, Sorger JI, Womer RB, Granowetter L, Grier HE, Gorlick RG, Laack NNI. Identification of Patients With Localized Ewing Sarcoma at Higher Risk for Local Failure: A Report From the Children's Oncology Group. Int J Radiat Oncol Biol Phys 2017. PubMed
  • Pretz JL, Barysauskas CM, George S, Hornick JL, Raut CP, Chen YE, Marcus KJ, Choy E, Hornicek F, Ready JE, DeLaney TF, Baldini EH. Localized Adult Ewing Sarcoma: Favorable Outcomes with Alternating Vincristine, Doxorubicin, Cyclophosphamide, and Ifosfamide, Etoposide (VDC/IE)-Based Multimodality Therapy. Oncologist 2017. PubMed
  • Storck S, Kennedy AL, Marcus KJ, Teot L, Vaughn J, Gnekow AK, Märkl B, Leuschner I, DuBois SG, French CA, Frühwald MC. Pediatric NUT-midline carcinoma: Therapeutic success employing a sarcoma based multimodal approach. Pediatr Hematol Oncol 2017; 34:231-237. PubMed
  • Li R, Polishchuk A, DuBois S, Hawkins R, Lee SW, Bagatell R, Shusterman S, Hill-Kayser C, Al-Sayegh H, Diller L, Haas-Kogan DA, Matthay KK, London WB, Marcus KJ. Patterns of Relapse in High-Risk Neuroblastoma Patients Treated With and Without Total Body Irradiation. Int J Radiat Oncol Biol Phys 2017; 97:270-277. PubMed
  • Kalapurakal JA, Gopalakrishnan M, Walterhouse DO, Helenowski I, Rigsby C, Kessel S, Laurie F, Katzenstein H, Ulin K, Rademaker A, Followill D, Morano K, Marcus KJ, Esiashvili N, Wolden SL, Mahajan A, Fitzgerald T. Final Report of a Prospective Clinical Trial of Cardiac Sparing Whole-Lung Intensity Modulated Radiation Therapy in Patients With Metastatic Pediatric Tumors. Int J Radiat Oncol Biol Phys 2016; 96:S118-S119. PubMed
  • Zacharoulis S, Morales La Madrid A, Bandopadhayay P, Chi SN, Manley P, Ullrich NN, Marcus K, Goumnerova L, Scott RM, Proctor M, Young-Poussaint T, De Girolami U, Kieran MW. Central Versus Extraventricular Neurocytoma in Children: A Clinicopathologic Comparison and Review of the Literature. J. Pediatr. Hematol. Oncol. 2016; 38:479-85. PubMed
  • Daw NC, Laack NN, McIlvaine EJ, Krailo M, Womer RB, Granowetter L, Grier HE, Marina NM, Bernstein ML, Gebhardt MC, Marcus KJ, Advani SM, Healey JH, Letson GD, Gorlick RG, Randall RL. Local Control Modality and Outcome for Ewing Sarcoma of the Femur: A Report From the Children's Oncology Group. Ann Surg Oncol 2016. PubMed
  • Kortmann RD, Freeman C, Marcus K, Claude L, Dieckmann K, Halperin E, Esiashvili N, Paulino A, Mahajan A, Seiersen K, Ahern V, Ricardi U, Carrie C. Paediatric radiation oncology in the care of childhood cancer: A position paper by the International Paediatric Radiation Oncology Society (PROS). Radiother Oncol 2016. PubMed
  • Yock TI, Yeap BY, Ebb DH, Weyman E, Eaton BR, Sherry NA, Jones RM, MacDonald SM, Pulsifer MB, Lavally B, Abrams AN, Huang MS, Marcus KJ, Tarbell NJ. Long-term toxic effects of proton radiotherapy for paediatric medulloblastoma: a phase 2 single-arm study. Lancet Oncol. 2016; 17:287-98. PubMed
  • Poorvu PD, Barton SE, Duncan CN, London WB, Laufer MR, Lehmann LE, Marcus KJ. Use and Effectiveness of GnRH Agonists for Prophylactic Menstrual Suppression in Post-Menarchal Females Undergoing Hematopoietic Cell Transplantation. J Pediatr Adolesc Gynecol 2015. PubMed
  • Bandopadhayay P, Silvera VM, Ciarlini PD, Malkin H, Bi WL, Bergthold G, Faisal AM, Ullrich NJ, Marcus K, Scott RM, Beroukhim R, Manley PE, Chi SN, Ligon KL, Goumnerova LC, Kieran MW. Myxopapillary ependymomas in children: imaging, treatment and outcomes. J. Neurooncol. 2015. PubMed
  • Lucas JT, Ladra MM, MacDonald SM, Busse PM, Friedmann AM, Ebb DH, Marcus KJ, Tarbell NJ, Yock TI. Proton therapy for pediatric and adolescent esthesioneuroblastoma. Pediatr Blood Cancer 2015. PubMed
  • Zhou ES, Manley PE, Marcus KJ, Recklitis CJ. Medical and Psychosocial Correlates of Insomnia Symptoms in Adult Survivors of Pediatric Brain Tumors. J Pediatr Psychol 2015. PubMed
  • DuBois SG, Krailo MD, Gebhardt MC, Donaldson SS, Marcus KJ, Dormans J, Shamberger RC, Sailer S, Nicholas RW, Healey JH, Tarbell NJ, Randall RL, Devidas M, Meyer JS, Granowetter L, Womer RB, Bernstein M, Marina N, Grier HE. Comparative evaluation of local control strategies in localized Ewing sarcoma of bone: a report from the Children's Oncology Group. Cancer 2015. PubMed
  • Marina N, Granowetter L, Grier HE, Womer RB, Randall RL, Marcus KJ, McIlvaine E, Krailo M. Age, Tumor Characteristics, and Treatment Regimen as Event Predictors in Ewing: A Children's Oncology Group Report. Sarcoma 2015; 2015:927123. PubMed
  • Tanguturi SK, George S, Marcus KJ, Demetri GD, Baldini EH. Whole Lung Irradiation in Adults with Metastatic Ewing Sarcoma: Practice Patterns and Implications for Treatment. Sarcoma 2015; 2015:591698. PubMed
  • Ladra MM, Szymonifka JD, Mahajan A, Friedmann AM, Yong Yeap B, Goebel CP, MacDonald SM, Grosshans DR, Rodriguez-Galindo C, Marcus KJ, Tarbell NJ, Yock TI. Preliminary results of a phase II trial of proton radiotherapy for pediatric rhabdomyosarcoma. J Clin Oncol 2014. PubMed
  • Chen MH, Blackington LH, Zhou J, Chu TF, Gauvreau K, Marcus KJ, Fisher DC, Diller LR, Ng AK. Blood pressure is associated with occult cardiovascular disease in prospectively studied Hodgkin lymphoma survivors after chest radiation. Leuk Lymphoma 2014. PubMed
  • Greenberger BA, Pulsifer MB, Ebb DH, MacDonald SM, Jones RM, Butler WE, Huang MS, Marcus KJ, Oberg JA, Tarbell NJ, Yock TI. Clinical outcomes and late endocrine, neurocognitive, and visual profiles of proton radiation for pediatric low-grade gliomas. Int J Radiat Oncol Biol Phys 2014; 89:1060-8. PubMed
  • Polishchuk AL, Li R, Hill-Kayser C, Little A, Hawkins RA, Hamilton J, Lau M, Tran HC, Strahlendorf C, Lemons RS, Weinberg V, Matthay KK, DuBois SG, Marcus KJ, Bagatell R, Haas-Kogan DA. Likelihood of bone recurrence in prior sites of metastasis in patients with high-risk neuroblastoma. Int J Radiat Oncol Biol Phys 2014. PubMed
  • Marcus KJ. Braching news about rhabdomyosarcoma. Pediatr Blood Cancer 2014. PubMed
  • Bandopadhayay P, Bergthold G, London WB, Goumnerova LC, Morales La Madrid A, Marcus KJ, Guo D, Ullrich NJ, Robison NJ, Chi SN, Beroukhim R, Kieran MW, Manley PE. Long-term outcome of 4,040 children diagnosed with pediatric low-grade gliomas: an analysis of the Surveillance Epidemiology and End Results (SEER) database. Pediatr Blood Cancer 2014. PubMed
  • Michaelson EM, Chen YH, Silver B, Tishler RB, Marcus KJ, Stevenson MA, Ng AK. Thyroid malignancies in survivors of Hodgkin lymphoma. Int J Radiat Oncol Biol Phys 2014; 88:636-41. PubMed
  • Sethi RV, Shih HA, Yeap BY, Mouw KW, Petersen R, Kim DY, Munzenrider JE, Grabowski E, Rodriguez-Galindo C, Yock TI, Tarbell NJ, Marcus KJ, Mukai S, MacDonald SM. Second nonocular tumors among survivors of retinoblastoma treated with contemporary photon and proton radiotherapy. Cancer 2014; 120:126-33. PubMed
  • Macdonald SM, Sethi R, Lavally B, Yeap BY, Marcus KJ, Caruso P, Pulsifer M, Huang M, Ebb D, Tarbell NJ, Yock TI. Proton radiotherapy for pediatric central nervous system ependymoma: clinical outcomes for 70 patients. 2013; 15:1552-9. PubMed
  • Friedmann AM, Wolfson JA, Hudson MM, Weinstein HJ, Link MP, Billett A, Larsen EC, Yock T, Donaldson SS, Marcus K, Krasin MJ, Howard SC, Metzger ML. Relapse after treatment of pediatric Hodgkin lymphoma: outcome and role of surveillance after end of therapy. Pediatr Blood Cancer 2013; 60:1458-63. PubMed
  • Benoit MM, Vargas SO, Bhattacharyya N, McGill TA, Robson CD, Ferraro N, Didas AE, Labow BI, Upton J, Taghinia A, Meara JG, Marcus KJ, Mack J, Rodriguez-Galindo C, Rahbar R. The presentation and management of mandibular tumors in the pediatric population. Laryngoscope 2013. PubMed
  • McBride SM, Raut CP, Lapidus M, Devlin PM, Marcus KJ, Bertagnolli M, George S, Baldini EH. Locoregional recurrence after preoperative radiation therapy for retroperitoneal sarcoma: adverse impact of multifocal disease and potential implications of dose escalation. Ann Surg Oncol 2013. PubMed
  • Ng AK, Garber JE, Diller LR, Birdwell RL, Feng Y, Neuberg DS, Silver B, Fisher DC, Marcus KJ, Mauch PM. Prospective study of the efficacy of breast magnetic resonance imaging and mammographic screening in survivors of Hodgkin lymphoma. J Clin Oncol 2013. PubMed
  • Baldini EH, Lapidus MR, Wang Q, Manola J, Orgill DP, Pomahac B, Marcus KJ, Bertagnolli MM, Devlin PM, George S, Abraham J, Ferrone ML, Ready JE, Raut CP. Predictors for major wound complications following preoperative radiotherapy and surgery for soft-tissue sarcoma of the extremities and trunk: importance of tumor proximity to skin surface. Ann Surg Oncol 2013; 20:1494-9. PubMed
  • Tsiamas P, Liu B, Cifter F, Ngwa WF, Berbeco RI, Kappas C, Theodorou K, Marcus K, Makrigiorgos MG, Sajo E, Zygmanski P. Impact of beam quality on megavoltage radiotherapy treatment techniques utilizing gold nanoparticles for dose enhancement. Phys Med Biol 2013; 58:451-64. PubMed
  • Womer RB, West DC, Krailo MD, Dickman PS, Pawel BR, Grier HE, Marcus K, Sailer S, Healey JH, Dormans JP, Weiss AR. Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: a report from the Children's Oncology Group. J Clin Oncol 2012; 30:4148-54. PubMed
  • Ebb D, Meyers P, Grier H, Bernstein M, Gorlick R, Lipshultz SE, Krailo M, Devidas M, Barkauskas DA, Siegal GP, Ferguson WS, Letson GD, Marcus K, Goorin A, Beardsley P, Marina N. Phase II trial of trastuzumab in combination with cytotoxic chemotherapy for treatment of metastatic osteosarcoma with human epidermal growth factor receptor 2 overexpression: a report from the children's oncology group. J Clin Oncol 2012; 30:2545-51. PubMed
  • Manley PE, McKendrick K, McGillicudy M, Chi SN, Kieran MW, Cohen LE, Kothare S, Michael Scott R, Goumnerova LC, Sun P, London W, Marcus KJ, Pomeroy SL, Ullrich NJ. Sleep dysfunction in long term survivors of craniopharyngioma. J. Neurooncol. 2012; 108:543-9. PubMed
  • Metzger ML, Weinstein HJ, Hudson MM, Billett AL, Larsen EC, Friedmann A, Howard SC, Donaldson SS, Krasin MJ, Kun LE, Marcus KJ, Yock TI, Tarbell N, Billups CA, Wu J, Link MP. Association between radiotherapy vs no radiotherapy based on early response to VAMP chemotherapy and survival among children with favorable-risk Hodgkin lymphoma. JAMA 2012; 307:2609-16. PubMed
  • Kelly PJ, Lin YB, Yu AY, Ropper AE, Nguyen PL, Marcus KJ, Hacker FL, Weiss SE. Linear accelerator-based stereotactic radiosurgery for brainstem metastases: the Dana-Farber/Brigham and Women's Cancer Center experience. J. Neurooncol. 2011. PubMed
  • Astrakas L, Blekas KD, Constantinou C, Andronesi OC, Mindrinos MN, Likas AC, Rahme LG, Black PM, Marcus KJ, Tzika AA. Combining magnetic resonance spectroscopy and molecular genomics offers better accuracy in brain tumor typing and prediction of survival than either methodology alone. Int J Oncol 2011; 38:1113-27. PubMed
  • Kelly PJ, Lin YB, Yu AY, Alexander BM, Hacker F, Marcus KJ, Weiss SE. Stereotactic Irradiation of the Postoperative Resection Cavity for Brain Metastasis: A Frameless Linear Accelerator-Based Case Series and Review of the Technique. Int J Radiat Oncol Biol Phys 2010. PubMed
  • Winkfield KM, Tsai HK, Yao X, Larson E, Neuberg D, Pomeroy SL, Ullrich NJ, Cohen LE, Kieran MW, Scott RM, Goumnerova LC, Marcus KJ. Long-term clinical outcomes following treatment of childhood craniopharyngioma. Pediatr Blood Cancer 2010. PubMed
  • Sawamura C, Springfield DS, Marcus KJ, Perez-Atayde AR, Gebhardt MC. Factors predicting local recurrence, metastasis, and survival in pediatric soft tissue sarcoma in extremities. Clin Orthop Relat Res 2010; 468:3019-27. PubMed
  • Galper SL, Yu JB, Mauch PM, Strasser JF, Silver B, Lacasce A, Marcus KJ, Stevenson MA, Chen MH, Ng AK. Clinically significant cardiac disease in patients with Hodgkin lymphoma treated with mediastinal irradiation. Blood 2010. PubMed
  • Ullrich NJ, Zimmerman M, Smith E, Irons M, Marcus K, Kieran MW. Association of Rapidly Progressive Moyamoya Syndrome With Bevacizumab Treatment for Glioblastoma in a Child With Neurofibromatosis Type 1. J Child Neurol 2010. PubMed
  • Wong JM, Chi SN, Marcus KJ, Levine BS, Ullrich NJ, MacDonald S, Lechpammer M, Goumnerova LC. Germinoma with malignant transformation to nongerminomatous germ cell tumor. J Neurosurg Pediatrics 2010; 6:295-8. PubMed
  • Robson CD, Rahbar R, Vargas SO, Marcus KJ, Mack JW, Licameli GR, Grier HE. Sinonasal and laryngeal carcinoma in children: correlation of imaging characteristics with clinicopathologic and cytogenetic features. AJNR Am J Neuroradiol 2010; 31:257-61. PubMed
  • Marcus KJ, Tishler RB. Head and neck carcinomas across the age spectrum: epidemiology, therapy, and late effects. Semin Radiat Oncol 2010; 20:52-7. PubMed
  • , Videtic GM, Gaspar LE, Aref AM, Germano IM, Goldsmith BJ, Imperato JP, Marcus KJ, McDermott MW, McDonald MW, Patchell RA, Robins HI, Rogers CL, Suh JH, Wolfson AH, Wippold FJ. American College of Radiology appropriateness criteria on multiple brain metastases. Int J Radiat Oncol Biol Phys 2009; 75:961-5. PubMed
  • Manley P,Li X,Turner C,Chi S,Zimmerman MA,Chordas C,Gordon A,Baker A,Ullrich NJ,Goumnerova L,Marcus K,Hoffman K,Kieran MW. A prospective, blinded analysis of A-PROTEIN (recoverin or CAR protein) levels in pediatric patients with central nervous system tumors. Pediatr Blood Cancer 2009; 53:343-7. PubMed
  • Granowetter L,Womer R,Devidas M,Krailo M,Wang C,Bernstein M,Marina N,Leavey P,Gebhardt M,Healey J,Shamberger RC,Goorin A,Miser J,Meyer J,Arndt CA,Sailer S,Marcus K,Perlman E,Dickman P,Grier HE. Dose-intensified compared with standard chemotherapy for nonmetastatic Ewing sarcoma family of tumors: a Children's Oncology Group Study. J Clin Oncol 2009; 27:2536-41. PubMed
  • Chi SN,Zimmerman MA,Yao X,Cohen KJ,Burger P,Biegel JA,Rorke-Adams LB,Fisher MJ,Janss A,Mazewski C,Goldman S,Manley PE,Bowers DC,Bendel A,Rubin J,Turner CD,Marcus KJ,Goumnerova L,Ullrich NJ,Kieran MW. Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor. J Clin Oncol 2009; 27:385-9. PubMed
  • Gutweiler JR, Yu DC, Kim HB, Kozakewich HP, Marcus KJ, Shamberger RC, Weldon CB. Hepatoblastoma presenting with focal nodular hyperplasia after treatment of neuroblastoma. J Pediatr Surg 2008; 43:2297-300. PubMed
  • Basu SK, Schwartz C, Fisher SG, Hudson MM, Tarbell N, Muhs A, Marcus KJ, Mendenhall N, Mauch P, Kun LE, Constine LS. Unilateral and bilateral breast cancer in women surviving pediatric Hodgkin's disease. Int J Radiat Oncol Biol Phys 2008; 72:34-40. PubMed
  • Gilheeney SW, Saad A, Chi S, Turner C, Ullrich NJ, Goumnerova L, Scott RM, Marcus K, Lehman L, De Girolami U, Kieran MW. Outcome of pediatric pineoblastoma after surgery, radiation and chemotherapy. J Neurooncol 2008; 89:89-95. PubMed
  • Hamacher M, Eisenacher M, Tribl F, Stephan C, Marcus K, Hardt T, Wiltfang J, Martens L, Desiderio D, Gutstein H, Park YM, Meyer HE. The HUPO Brain Proteome Project Wish List - Summary of the 9(th) HUPO BPP Workshop 9-10 January 2008, Barbados. Proteomics 2008; 8:2160-4. PubMed
  • Hamacher M, Stephan C, Hardt T, Eisenacher M, Henkel A, Wiltfang J, Jimenez CR, Park YM, Marcus K, Meyer HE. Applications in brain proteomics: 8(th) HUPO Brain Proteome Project Workshop 7 October 2007, Seoul, Korea. Proteomics 2008; 8:1750-3. PubMed
  • Hamacher M, Hardt T, van Hall A, Stephan C, Marcus K, Meyer HE. Inside SMP proteomics: six years German Human Brain Proteome Project (HBPP) - a summary. Proteomics 2008; 8:1118-28. PubMed
  • Schuchhardt J, Glintschert A, Hartl D, Irmler M, Beckers J, Stephan C, Marcus K, Klose J, Meyer HE, Malik A. BrainProfileDB - a platform for integration of functional genomics data. Proteomics 2008; 8:1162-4. PubMed
  • Liu AK, Marcus KJ, Fischl B, Grant PE, Young Poussaint T, Rivkin MJ, Davis P, Tarbell NJ, Yock TI. Changes in cerebral cortex of children treated for medulloblastoma. Int J Radiat Oncol Biol Phys 2007; 68:992-8. PubMed
  • Ullrich NJ, Robertson R, Kinnamon DD, Scott RM, Kieran MW, Turner CD, Chi SN, Goumnerova L, Proctor M, Tarbell NJ, Marcus KJ, Pomeroy SL. Moyamoya following cranial irradiation for primary brain tumors in children. Neurology 2007; 68:932-8. PubMed
  • Marcus KJ, Astrakas LG, Zurakowski D, Zarifi MK, Mintzopoulos D, Poussaint TY, Anthony DC, De Girolami U, Black PM, Tarbell NJ, Tzika AA. Predicting survival of children with CNS tumors using proton magnetic resonance spectroscopic imaging biomarkers. Int J Oncol 2007; 30:651-7. PubMed
  • Turner CD, Chi S, Marcus KJ, MacDonald T, Packer RJ, Poussaint TY, Vajapeyam S, Ullrich N, Goumnerova LC, Scott RM, Briody C, Chordas C, Zimmerman MA, Kieran MW. Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme. J Neurooncol 2007; 82:95-101. PubMed
  • Saad AG, Sachs J, Turner CD, Proctor M, Marcus KJ, Wang L, Lidov H, Ullrich NJ. Extracranial metastases of glioblastoma in a child: case report and review of the literature. J Pediatr Hematol Oncol 2007; 29:190-4. PubMed
  • Donaldson SS, Link MP, Weinstein HJ, Rai SN, Brain S, Billett AL, Hurwitz CA, Krasin M, Kun LE, Marcus KC, Tarbell NJ, Young JA, Hudson MM. Final results of a prospective clinical trial with VAMP and low-dose involved-field radiation for children with low-risk Hodgkin's disease. J Clin Oncol 2007; 25:332-7. PubMed
  • Squire SE, Chan MD, Marcus KJ. Atypical teratoid/rhabdoid tumor: the controversy behind radiation therapy. J Neurooncol 2007; 81:97-111. PubMed
  • Ng AK, Li S, Neuberg D, Fisher DC, McMillan C, Silver B, Marcus KC, Stevenson MA, Mauch PM. Long-term results of a prospective trial of mantle irradiation alone for early-stage Hodgkin's disease. Ann Oncol 2006; 17:1693-7. PubMed
  • Ullrich NJ, Marcus K, Pomeroy SL, Turner CD, Zimmerman M, Lehmann LE, Scott RM, Goumnerova L, Gillan E, Kieran MW, Chi SN. Transverse Myelitis After Therapy For Primitive Neuroectodermal Tumors. Pediatr Neurol 2006; 35:122-125. PubMed
  • George RE, Li S, Medeiros-Nancarrow C, Neuberg D, Marcus K, Shamberger RC, Pulsipher M, Grupp SA, Diller L. High-risk neuroblastoma treated with tandem autologous peripheral-blood stem cell-supported transplantation: long-term survival update. J Clin Oncol 2006; 24:2891-6. PubMed
  • Rahbar R, Grimmer JF, Vargas SO, Robson CD, Mack JW, Perez-Atayde AR, Marcus KJ, Grier HE, Healy GB, McGill TJ. Mucoepidermoid carcinoma of the parotid gland in children: A 10-year experience. Arch Otolaryngol Head Neck Surg 2006; 132:375-80. PubMed
  • Suh JH, Videtic GM, Aref AM, Germano I, Goldsmith BJ, Imperato JP, Marcus KJ, McDermott MW, McDonald MW, Patchell RA, Robins HI, Rogers CL, Wolfson AH, Wippold FJ, Gaspar LE. ACR Appropriateness Criteria: single brain metastasis. Curr Probl Cancer ; 34:162-74. PubMed
  • Liu KX, Chen YH, Kozono D, Mak RH, Boyle PJ, Janeway KA, Mullen EA, Marcus KJ. Phase I/II Study of Stereotactic Body Radiation Therapy for Pulmonary Metastases in Pediatric Patients. Adv Radiat Oncol ; 5:1267-1273. PubMed
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DF/HCC members that share similar concepts* with Karen Jean C. Marcus, MD but have yet to coauthor a publication with this researcher.

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