Photo of Lydia Pace,  MD, MPH

Lydia Pace, MD, MPH

Brigham And Women's Hospital

Brigham And Women's Hospital


lepace@partners.org

Lydia Pace, MD, MPH

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Assistant Professor, Medicine, Harvard Medical School
  • Assistant Professor, Medicine, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

I am interested in decision-making about breast cancer screening and genetic testing both at a policy level and the level of the individual clinician and patient. I am also interested in breast cancer screening policies and early detection strategies in low- and middle-income countries, and using implementation science to inform effective and feasible strategies in such settings. I am also working increasingly on the quality of breast cancer care in low- and middle-income countries. My clinical practice is in primary care internal medicine at the Phyllis Jen Center for Primary Care at BWH. I also care for individuals at elevated risk of developing breast cancer in the BWH Breast Cancer Personalized Risk Assessment, Education and Prevention (B-PREP) Program. I precept BWH internal medicine residents and regularly give lectures about breast cancer screening and cancer screening more generally.

Publications from Harvard Catalyst Profiles

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  • Bychkovsky B, Laws A, Katlin F, Hans M, Knust Graichen M, Pace LE, Scheib R, Garber JE, King TA. Initiation and tolerance of chemoprevention among women with high-risk breast lesions: the potential of low-dose tamoxifen. Breast Cancer Res Treat 2022. PubMed
  • Ganguli I, Keating NL, Thakore N, Lii J, Raza S, Pace LE. Downstream Mammary and Extramammary Cascade Services and Spending Following Screening Breast Magnetic Resonance Imaging vs Mammography Among Commercially Insured Women. JAMA Netw Open 2022; 5:e227234. PubMed
  • Morgan KM, Hamilton JG, Symecko H, Kamara D, Jenkins C, Lester J, Spielman K, Pace LE, Gabriel C, Levin JD, Tejada PR, Braswell A, Marcell V, Wildman T, Devolder B, Baum RC, Block JN, Fesko Y, Boehler K, Howell V, Heitler J, Robson ME, Nathanson KL, Tung N, Karlan BY, Domchek SM, Garber JE, Offit K. Targeted BRCA1/2 population screening among Ashkenazi Jewish individuals using a web-enabled medical model: An observational cohort study. Genet Med 2022; 24:564-575. PubMed
  • Pace LE, Tung N, Lee YS, Hamilton JG, Gabriel C, Revette A, Raja S, Jenkins C, Braswell A, Morgan K, Levin J, Block J, Domchek SM, Nathanson K, Symecko H, Spielman K, Karlan B, Kamara D, Lester J, Offit K, Garber JE, Keating NL. Challenges and Opportunities in Engaging Primary Care Providers in BRCA Testing: Results from the BFOR Study. J Gen Intern Med 2021. PubMed
  • Erfani P, Bhangdia K, Stauber C, Mugunga JC, Pace LE, Fadelu T. Economic Evaluations of Breast Cancer Care in Low- and Middle-Income Countries: A Scoping Review. Oncologist 2021. PubMed
  • Hawkins SS, Horvath K, Cohen J, Pace LE, Baum CF. Associations between ACA-related policies and a clinical recommendation with HPV vaccine initiation. Cancer Causes Control 2021. PubMed
  • Becker NV, Keating NL, Pace LE. ACA Mandate Led To Substantial Increase In Contraceptive Use Among Women Enrolled In High-Deductible Health Plans. Health Aff (Millwood) 2021; 40:579-586. PubMed
  • Erfani P, Bhangdia K, Mugunga JC, Pace LE, Fadelu T. Cost of breast cancer care in low and middle-income countries: a scoping review protocol. JBI Evid Synth 2021. PubMed
  • Gebremariam A, Assefa M, Addissie A, Worku A, Dereje N, Abreha A, Tigeneh W, Pace LE, Kantelhardt EJ, Jemal A. Delayed initiation of adjuvant chemotherapy among women with breast cancer in Addis Ababa, Ethiopia. Breast Cancer Res Treat 2021. PubMed
  • Hawkins SS, Horvath K, Cohen J, Pace LE, Baum CF. Associations between insurance-related affordable care act policy changes with HPV vaccine completion. BMC Public Health 2021; 21:304. PubMed
  • Pace LE, Keating NL. Should Women at Lower-Than-Average Risk of Breast Cancer Undergo Less Frequent Screening? Journal of the National Cancer Institute 2021. PubMed
  • O'Neil DS, Nxumalo S, Ngcamphalala C, Tharp G, Jacobson JS, Nuwagaba-Biribonwoha H, Dlamini X, Pace LE, Neugut AI, Harris TG. Breast Cancer Early Detection in Eswatini: Evaluation of a Training Curriculum and Patient Receipt of Recommended Follow-Up Care. JCO Glob Oncol 2021; 7:1349-1357. PubMed
  • Gebremariam A, Dereje N, Addissie A, Worku A, Assefa M, Abreha A, Tigeneh W, Pace LE, Kantelhardt EJ, Jemal A. Factors associated with late-stage diagnosis of breast cancer among women in Addis Ababa, Ethiopia. Breast Cancer Res Treat 2020. PubMed
  • Pace LE, Baum CF, Horvath K, Raja SC, Cohen J, Hawkins SS. BRCA1/2 Testing in Massachusetts Among Women With Private Insurance or Medicaid, 2011-2015. Med Care 2020. PubMed
  • Raza S, Frost E, Kwait D, Bowerson M, Rugema V, Hategekimana V, Umwizerwa A, Shabani K, Shulman L, Lee YS, Huang CC, Mpunga T, Shyirambere C, Vianney Dusengimana JM, Pace LE. Training Nonradiologist Clinicians in Diagnostic Breast Ultrasound in Rural Rwanda: Impact on Knowledge and Skills. J Am Coll Radiol 2020. PubMed
  • Pace LE, Schleimer LE, Shyirambere C, Ilbawi A, Dusengimana JMV, Bigirimana JB, Uwizeye FR, Chamberlin M, Lee YS, Shulman LN, Troyan S, Anderson BO, Duggan C, O'Neil DS, Dvaladze A, Brock J, Nguyen C, Ruhangaza D, Habimana O, Nsabimana N, Butonzi J, Nkusi E, Mpunga T, Keating NL. Identifying Breast Cancer Care Quality Measures for a Cancer Facility in Rural Sub-Saharan Africa: Results of a Systematic Literature Review and Modified Delphi Process. JCO Glob Oncol 2020; 6:1446-1454. PubMed
  • Pace LE, Lee YS, Tung N, Hamilton JG, Gabriel C, Raja SC, Jenkins C, Braswell A, Domchek SM, Symecko H, Spielman K, Karlan BY, Lester J, Kamara D, Levin J, Morgan K, Offit K, Garber J, Keating NL. Comparison of up-front cash cards and checks as incentives for participation in a clinician survey: a study within a trial. 2020; 20:210. PubMed
  • Rubagumya F, Costas-Chavarri A, Manirakiza A, Murenzi G, Uwinkindi F, Ntizimira C, Rukundo I, Mugenzi P, Rugwizangoga B, Shyirambere C, Urusaro S, Pace L, Buswell L, Ntirenganya F, Rudakemwa E, Fadelu T, Mpunga T, Shulman LN, Booth CM. State of Cancer Control in Rwanda: Past, Present, and Future Opportunities. JCO Glob Oncol 2020; 6:1171-1177. PubMed
  • Pace LE. Dense Breast Notification Legislation: More Reasons for Caution. J Gen Intern Med 2020. PubMed
  • Ginsburg O, Yip CH, Brooks A, Cabanes A, Caleffi M, Dunstan Yataco JA, Gyawali B, McCormack V, McLaughlin de Anderson M, Mehrotra R, Mohar A, Murillo R, Pace LE, Paskett ED, Romanoff A, Rositch AF, Scheel JR, Schneidman M, Unger-SaldaƱa K, Vanderpuye V, Wu TY, Yuma S, Dvaladze A, Duggan C, Anderson BO. Breast cancer early detection: A phased approach to implementation. Cancer 2020; 126 Suppl 10:2379-2393. PubMed
  • Haakenstad A, Hawkins SS, Pace LE, Cohen J. Rural-urban disparities in colonoscopies after the elimination of patient cost-sharing by the Affordable Care Act. Prev Med 2019; 129:105877. PubMed
  • Gebremariam A, Addissie A, Worku A, Assefa M, Pace LE, Kantelhardt EJ, Jemal A. Time intervals experienced between first symptom recognition and pathologic diagnosis of breast cancer in Addis Ababa, Ethiopia: a cross-sectional study. BMJ Open 2019; 9:e032228. PubMed
  • Pace LE, Dusengimana JMV, Shulman LN, Schleimer LE, Shyirambere C, Rusangwa C, Muvugabigwi G, Park PH, Huang C, Bigirimana JB, Hategekimana V, Rugema V, Umwizerwa A, Keating NL, Mpunga T. Cluster Randomized Trial to Facilitate Breast Cancer Early Diagnosis in a Rural District of Rwanda. J Glob Oncol 2019; 5:1-13. PubMed
  • Schleimer LE, Vianney Dusengimana JM, Butonzi J, Kigonya C, Natarajan A, Umwizerwa A, O'Neil DS, Costas-Chavarri A, Majyambere JP, Shulman LN, Keating NL, Shyirambere C, Mpunga T, Pace LE. Barriers to timely surgery for breast cancer in Rwanda. Surgery 2019. PubMed
  • Saulsberry L, Pace LE, Keating NL. The Impact of Breast Density Notification Laws on Supplemental Breast Imaging and Breast Biopsy. J Gen Intern Med 2019. PubMed
  • Keating NL, Pace LE. New Federal Requirements to Inform Patients About Breast Density: Will They Help Patients? JAMA 2019. PubMed
  • Pace LE, Percac-Lima S, Nguyen KH, Crofton CN, Normandin KA, Singer SJ, Rosenthal MB, Chien AT. Comparing Diagnostic Evaluations for Rectal Bleeding and Breast Lumps in Primary Care: a Retrospective Cohort Study. J Gen Intern Med 2019. PubMed
  • Gebremariam A, Addissie A, Worku A, Hirpa S, Assefa M, Pace LE, Kantelhardt EJ, Jemal A. Breast and cervical cancer patients' experience in Addis Ababa city, Ethiopia: a follow-up study protocol. BMJ Open 2019; 9:e027034. PubMed
  • Weiss A, Grossmith S, Cutts D, Mikami SA, Suskin JA, Graichen MK, Rojas NA, Pace LE, Joyce E, Rhei E, Scheib R, Bychkovsky B, Garber JE, Morganstern D, King TA. Customized breast cancer risk assessment in an ambulatory clinic: a portal for identifying women at risk. Breast Cancer Res Treat 2019. PubMed
  • Pace LE, Keating NL. Medications to Reduce Breast Cancer Risk: Promise and Limitations. JAMA 2019; 322:821-823. PubMed
  • Martin AN, Kaneza KM, Kulkarni A, Mugenzi P, Ghebre R, Ntirushwa D, Ilbawi AM, Pace LE, Costas-Chavarri A. Cancer Control at the District Hospital Level in Sub-Saharan Africa: An Educational and Resource Needs Assessment of General Practitioners. J Glob Oncol 2019; 5:1-8. PubMed
  • Keating NL, Pace LE. A Promising Tool to Increase Individualized Discussions About Lifestyle Risk Factors for Breast Cancer. J Womens Health (Larchmt) 2018. PubMed
  • Pace LE, Dusengimana JV, Keating NL, Hategekimana V, Rugema V, Bigirimana JB, Costas-Chavarri A, Umwizera A, Park PH, Shulman LN, Mpunga T. Impact of Breast Cancer Early Detection Training on Rwandan Health Workers' Knowledge and Skills. J Glob Oncol 2018. PubMed
  • O'Neil DS, Keating NL, Dusengimana JMV, Hategekimana V, Umwizera A, Mpunga T, Shulman LN, Pace LE. Quality of Breast Cancer Treatment at a Rural Cancer Center in Rwanda. J Glob Oncol 2018. PubMed
  • Dusengimana JMV, Hategekimana V, Borg R, Hedt-Gauthier B, Gupta N, Troyan S, Shulman LN, Nzayisenga I, Fadelu T, Mpunga T, Pace LE. Pregnancy-associated breast cancer in rural Rwanda: the experience of the Butaro Cancer Center of Excellence. BMC Cancer 2018; 18:634. PubMed
  • Keating NL, Pace LE. Breast Cancer Screening in 2018: Time for Shared Decision Making. JAMA 2018; 319:1814-1815. PubMed
  • Martei YM, Pace LE, Brock JE, Shulman LN. Breast Cancer in Low- and Middle-Income Countries: Why We Need Pathology Capability to Solve This Challenge. Clin. Lab. Med. 2018; 38:161-173. PubMed
  • Percac-Lima S, Pace LE, Nguyen KH, Crofton CN, Normandin KA, Singer SJ, Rosenthal MB, Chien AT. Diagnostic Evaluation of Patients Presenting to Primary Care with Rectal Bleeding. J Gen Intern Med 2018. PubMed
  • Freedman RA, Keating NL, Pace LE, Lii J, McCarthy EP, Schonberg MA. Use of Surveillance Mammography Among Older Breast Cancer Survivors by Life Expectancy. J Clin Oncol 2017; 35:3123-3130. PubMed
  • Pace LE, Dusengimana JV, Hategekimana V, Habineza H, Bigirimana JB, Tapela N, Mutumbira C, Mpanumusingo E, Brock JE, Meserve E, Uwumugambi A, Dillon D, Keating NL, Shulman LN, Mpunga T. Benign and Malignant Breast Disease at Rwanda's First Public Cancer Referral Center. Oncologist 2016. PubMed
  • Pace LE, Mpunga T, Hategekimana V, Dusengimana JM, Habineza H, Bigirimana JB, Mutumbira C, Mpanumusingo E, Ngiruwera JP, Tapela N, Amoroso C, Shulman LN, Keating NL. Delays in Breast Cancer Presentation and Diagnosis at Two Rural Cancer Referral Centers in Rwanda. Oncologist 2015; 20:780-8. PubMed
  • Pace LE, Keating NL. A systematic assessment of benefits and risks to guide breast cancer screening decisions. JAMA 2014; 311:1327-35. PubMed
  • Pace LE, He Y, Keating NL. Trends in mammography screening rates after publication of the 2009 US Preventive Services Task Force recommendations. Cancer 2013. PubMed
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