Research Abstract
The mission of the Hill Lab is to develop a deep mechanistic understanding of ovarian cancer development and progression which we will harness to make ovarian cancer a more manageable disease for all patients through the development of effective methods of early detection, more personalized treatment, and better therapeutic strategies.
In pursuit of this mission, the Hill lab focuses on understanding the role of the DNA damage response in ovarian carcinogenesis, tumor evolution, the anti-tumor immune response, and therapeutic sensitivity and resistance.
We utilize molecular and cellular biology, immunology, sequencing, and imaging techniques in ovarian cancer cell lines, patient-derived normal and ovarian cancer organoids, and ovarian cancer mouse models.
