Photo of Tianyi Huang,  ScD

Tianyi Huang, ScD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 525-2087
Fax: (617) 525-2008


tih541@mail.harvard.edu

Tianyi Huang, ScD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Instructor, Medicine, Harvard Medical School
  • Associate Epidemiologist, Medicine, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

Despite compelling experimental evidence supporting an important role of sleep and circadian mechanisms in carcinogenesis and tumor progression, population-based studies yielded very mixed findings regarding the relationships of sleep quality, sleep disorders and circadian disruption with cancer incidence and mortality. A notable limitation of prior studies is the reliance on subjective and crude assessment of sleep. Recent advances in mobile health technologies provide an opportunity to objectively measure and subtype sleep and sleep disorders in greater detail. I'm interested in applying these technologies in large population-based cohorts to understand the role of sleep and sleep disorders in cancer etiology and survivorship.

Publications

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  • Tabung FK, Liang L, Huang T, Balasubramanian R, Zhao Y, Chandler PD, Manson JE, Cespedes Feliciano EM, Hayden KM, Van Horn L, Clish CB, Giovannucci EL, Rexrode KM. Identifying metabolomic profiles of inflammatory diets in postmenopausal women. 2019. PubMed
  • Huang T, Trudel-Fitzgerald C, Poole EM, Sawyer S, Kubzansky LD, Hankinson SE, Okereke OI, Tworoger SS. The Mind-Body Study: study design and reproducibility and interrelationships of psychosocial factors in the Nurses' Health Study II. Cancer Causes Control 2019. PubMed
  • Baden MY, Satija A, Hu FB, Huang T. Change in Plant-Based Diet Quality Is Associated with Changes in Plasma Adiposity-Associated Biomarker Concentrations in Women. J Nutr 2019. PubMed
  • Huang T, Tworoger SS, Willett WC, Stampfer MJ, Rosner BA. Associations of early life and adulthood adiposity with risk of epithelial ovarian cancer. Ann. Oncol. 2019; 30:303-309. PubMed
  • Reid M, Maras JE, Shea S, Wood AC, Castro-Diehl C, Johnson DA, Huang T, Jacobs DR, Crawford A, St-Onge MP, Redline S. Association between diet quality and sleep apnea in the Multi-Ethnic Study of Atherosclerosis. Sleep 2019. PubMed
  • Huang T, Glass K, Zeleznik OA, Kang JH, Ivey KL, Sonawane AR, Birmann BM, Hersh CP, Hu FB, Tworoger SS. A Network Analysis of Biomarkers for Type 2 Diabetes. Diabetes 2018. PubMed
  • Huang T, Zeleznik OA, Poole EM, Clish CB, Deik AA, Scott JM, Vetter C, Schernhammer ES, Brunner R, Hale L, Manson JE, Hu FB, Redline S, Tworoger SS, Rexrode KM. Habitual sleep quality, plasma metabolites and risk of coronary heart disease in post-menopausal women. Int J Epidemiol 2018. PubMed
  • Huang T, Lin BM, Markt SC, Stampfer MJ, Laden F, Hu FB, Tworoger SS, Redline S. Sex differences in the associations of obstructive sleep apnoea with epidemiological factors. Eur. Respir. J. 2018. PubMed
  • Huang T, Lin BM, Redline S, Curhan GC, Hu FB, Tworoger SS. Type of Menopause, Age at Menopause, and Risk of Developing Obstructive Sleep Apnea in Postmenopausal Women. Am J Epidemiol 2018. PubMed
  • Huang T, Lin BM, Stampfer MJ, Tworoger SS, Hu FB, Redline S. A Population-Based Study of the Bidirectional Association Between Obstructive Sleep Apnea and Type 2 Diabetes in Three Prospective U.S. Cohorts. Diabetes Care 2018; 41:2111-2119. PubMed
  • Li J, Rice MS, Huang T, Hankinson SE, Clevenger CV, Hu FB, Tworoger SS. Circulating prolactin concentrations and risk of type 2 diabetes in US women. Diabetologia 2018; 61:2549-2560. PubMed
  • Huang T, Poole EM, Vetter C, Rexrode KM, Kubzansky LD, Schernhammer E, Rohleder N, Hu FB, Redline S, Tworoger SS. Habitual sleep quality and diurnal rhythms of salivary cortisol and dehydroepiandrosterone in postmenopausal women. Psychoneuroendocrinology 2017; 84:172-180. PubMed
  • Tabung FK, Huang T, Giovannucci EL, Smith-Warner SA, Tworoger SS, Poole EM. The inflammatory potential of diet and ovarian cancer risk: results from two prospective cohort studies. Br J Cancer 2017; 117:907-911. PubMed
  • AlEssa HB, Malik VS, Yuan C, Willett WC, Huang T, Hu FB, Tobias DK. Dietary patterns and cardiometabolic and endocrine plasma biomarkers in US women. Am J Clin Nutr 2016; 105:432-441. PubMed
  • Ertel KA, Huang T, Rifas-Shiman SL, Kleinman K, Rich-Edwards J, Oken E, James-Todd T. Perinatal weight and risk of prenatal and postpartum depressive symptoms. Ann Epidemiol 2018; 27:695-700.e1. PubMed
  • James-Todd TM, Meeker JD, Huang T, Hauser R, Ferguson KK, Rich-Edwards JW, McElrath TF, Seely EW. Pregnancy urinary phthalate metabolite concentrations and gestational diabetes risk factors. Environ Int 2016; 96:118-126. PubMed
  • Huang T, Tworoger SS, Hecht JL, Rice MS, Sood AK, Kubzansky LD, Poole EM. Association of ovarian tumor β2-adrenergic receptor status with ovarian cancer risk factors and survival. Cancer Epidemiol Biomarkers Prev 2016. PubMed
  • James-Todd TM, Huang T, Seely EW, Saxena AR. The association between phthalates and metabolic syndrome: the National Health and Nutrition Examination Survey 2001-2010. Environ Health 2018; 15:52. PubMed
  • Huang T, Tobias DK, Hruby A, Rifai N, Tworoger SS, Hu FB. An Increase in Dietary Quality Is Associated with Favorable Plasma Biomarkers of the Brain-Adipose Axis in Apparently Healthy US Women. J Nutr 2016. PubMed
  • Huang T, Poole EM, Eliassen AH, Okereke OI, Kubzansky LD, Sood AK, Forman JP, Tworoger SS. Hypertension, use of antihypertensive medications, and risk of epithelial ovarian cancer. Int. J. Cancer 2016. PubMed
  • James-Todd TM, Meeker JD, Huang T, Hauser R, Seely EW, Ferguson KK, Rich-Edwards JW, McElrath TF. Racial and ethnic variations in phthalate metabolite concentration changes across full-term pregnancies. J Expo Sci Environ Epidemiol 2016. PubMed
  • Tworoger SS, Huang T. Obesity and Ovarian Cancer. Recent Results Cancer Res 2016; 208:155-176. PubMed
  • Li Y, Huang T, Zheng Y, Muka T, Troup J, Hu FB. Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials. J Am Heart Assoc 2016. PubMed
  • Tian Y, Jiang C, Wang M, Cai R, Zhang Y, He Z, Wang H, Wu D, Wang F, Liu X, He Z, An P, Wang M, Tang Q, Yang Y, Zhao J, Lv S, Zhou W, Yu B, Lan J, Yang X, Zhang L, Tian H, Gu Z, Song Y, Huang T, McNaughton LR. BMI, leisure-time physical activity, and physical fitness in adults in China: results from a series of national surveys, 2000-14. Lancet Diabetes Endocrinol 2018; 4:487-97. PubMed
  • Huang T, Poole EM, Okereke OI, Kubzansky LD, Eliassen AH, Sood AK, Wang M, Tworoger SS. Depression and risk of epithelial ovarian cancer: Results from two large prospective cohort studies. Gynecol Oncol 2015; 139:481-6. PubMed
  • Huang T, Eliassen AH, Hankinson SE, Okereke OI, Kubzansky LD, Wang M, Poole EM, Chavarro JE, Tworoger SS. A prospective study of leisure-time physical activity and risk of incident epithelial ovarian cancer: Impact by menopausal status. Int J Cancer 2015. PubMed
  • Huang T, Rifas-Shiman SL, Ertel KA, Rich-Edwards J, Kleinman K, Gillman MW, Oken E, James-Todd T. Pregnancy Hyperglycaemia and Risk of Prenatal and Postpartum Depressive Symptoms. Paediatr Perinat Epidemiol 2015; 29:281-9. PubMed
  • Cassidy A, Huang T, Rice MS, Rimm EB, Tworoger SS. Intake of dietary flavonoids and risk of epithelial ovarian cancer. Am J Clin Nutr 2014; 100:1344-51. PubMed
  • Huang T, Saxena AR, Isganaitis E, James-Todd T. Gender and racial/ethnic differences in the associations of urinary phthalate metabolites with markers of diabetes risk: National Health and Nutrition Examination Survey 2001-2008. Environ Health 2018; 13:6. PubMed
  • James-Todd T, Stahlhut R, Meeker JD, Powell SG, Hauser R, Huang T, Rich-Edwards J. Urinary Phthalate Metabolite Concentrations and Diabetes among Women in the National Health and Nutrition Examination Survey (NHANES) 2001-2008. Environ Health Perspect 2012; 120:1307-13. PubMed
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