Photo of Charlotta Lindvall, MD, PhD

Charlotta Lindvall, MD, PhD

Dana-Farber Cancer Institute

Dana-Farber Cancer Institute
Phone: (617) 582-9317


Charlotta_Lindvall@dfci.harvard.edu

Photo of Charlotta Lindvall, MD, PhD

Dana-Farber Cancer Institute
Phone: (617) 582-9317


Charlotta_Lindvall@dfci.harvard.edu

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Charlotta Lindvall, MD, PhD

Dana-Farber Cancer Institute

EDUCATIONAL TITLES

  • Assistant Professor, Medicine, Harvard Medical School
  • Physician, Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute

HCC PROGRAM AFFILIATION

Research Abstract

My ultimate goal is to develop and implement scalable quality improvement programs that utilize methods such as natural language processing (NLP) and deep learning. Developing and testing a novel NLP-based approach to capture palliative care quality measures is a strategic step toward these goals, with ample opportunity for extension and tremendous potential to improve clinical care.

Publications from Harvard Catalyst Profiles

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  • Tentor Z, Finnemore A, Miller PJ, Davis J, Juarez Martinez E, Lindvall C, Kimchi EY, Rhee JY. Occurrence Rates of Delirium in Brain Tumor Patients: A Systematic Review and Meta-Analysis. Cancers (Basel) 2025. PubMed
  • Volandes AE, Chang Y, Lakin JR, Paasche-Orlow MK, Lindvall C, Zupanc SN, Martins-Welch D, Carney MT, Burns EA, Itty J, Emmert-Tangredi K, Martin NJ, Sanghani S, Tilburt J, Pollak KI, Davis AD, Garde C, Barry MJ, El-Jawahri A, Quintiliani L, Sciacca K, Goldman J, Tulsky JA. An Intervention to Increase Advance Care Planning Among Older Adults With Advanced Cancer: A Randomized Clinical Trial. JAMA Netw Open 2025; 8:e259150. PubMed
  • Agaronnik ND, Davis J, Manz CR, Tulsky JA, Lindvall C. Feasibility Study for Using Large Language Models to Identify Goals-of-Care Documentation at Scale in Patients With Advanced Cancer. JCO Oncol Pract 2025. PubMed
  • Pozzar RA, Tulsky JA, Berry DL, Batista J, Barwick P, Lindvall CJ, Dykes PC, Manni M, Matulonis UA, McCleary NJ, Wright AA. Usability, Acceptability, and Barriers to Implementation of a Collaborative Agenda-Setting Intervention (CASI) to Promote Person-Centered Ovarian Cancer Care: Development Study. JMIR Cancer 2025; 11:e66801. PubMed
  • Durieux BN, Zverev SR, Agaronnik ND, Davis J, Pollak KI, Tulsky JA, Tarbi E, Lindvall C. Physician-dominated conversations: An analysis of illness understanding discussions among patients with advanced cancer. Patient Educ Couns 2025; 133:108633. PubMed
  • Agaronnik ND, Davis J, Manz CR, Tulsky JA, Lindvall C. Large language models to identify advance care planning in patients with advanced cancer. J Pain Symptom Manage 2024. PubMed
  • Hachem Y, Lakin J, Teuteberg W, Cullinan A, Gonzales MJ, Lindvall C, Kumar P, Dingfield L, Kilpatrick L, Greenwald J, Miller A, Keeney T, Fromme EK, Paladino J. Electronic Health Record Serious Illness Conversation Dashboards: An Implementation Case Series. J Pain Symptom Manage 2024. PubMed
  • Walling AM, Lorenz KA, Yuan A, O'Hanlon CE, McClean M, Ljungberg BF, Giannitrapani KF, Bozkurt S, Anand S, Glaspy J, Wenger NS, Lindvall C. Creating a Learning Health System in a Cancer Center: Generalizability of an Electronic Health Record Phenotype for Advanced Solid Cancer. JCO Oncol Pract 2024. PubMed
  • Bozkurt S, Fereydooni S, Kar I, Diop Chalmers C, Leslie SL, Pathak R, Walling A, Lindvall C, Lorenz K, Quest T, Giannitrapani K, Kavalieratos D. Investigating Data Diversity and Model Robustness of AI Applications in Palliative Care and Hospice: Protocol for Scoping Review. JMIR Res Protoc 2024; 13:e56353. PubMed
  • Cotner CE, Tramontano AC, Post A, Finn B, Awan S, Gwynne N, Mwesigwa S, Lindvall C, Tulsky JA, Jacobson JO, Jackman DM, Wright AA, Manz CR. Using Oncology Treatment Pathway Data to Evaluate Serious Illness Communication, Care Utilization, and End-of-Life Care for Patients With Cancer. JCO Oncol Pract 2024. PubMed
  • Lindsay ME, de Oliveira S, Sciacca K, Lindvall C, Ananth PJ. Harnessing Natural Language Processing to Assess Quality of End-of-Life Care for Children With Cancer. JCO Clin Cancer Inform 2024; 8:e2400134. PubMed
  • Dhawale TM, Bhat RS, Johnson PC, Srikonda S, Lau-Min KS, Boateng K, Lee H, Amonoo HL, Nipp R, Lindvall C, El-Jawahri A. Telemedicine-based serious illness conversations, healthcare utilization, and end of life care among patients with advanced lung cancer. Oncologist 2024. PubMed
  • Durieux BN, Zupanc SN, Tarbi EC, Manz CR, Lakin JR, Lindvall C. Content Analysis of Serious Illness Conversation Documentation: Structured vs. Free-Text Information. J Pain Symptom Manage 2024. PubMed
  • Pozzar RA, Enzinger AC, Howard C, Tavormina A, Matulonis UA, Campos S, Liu JF, Horowitz N, Konstantinopoulos PA, Krasner C, Wall JA, Sciacca K, Meyer LA, Lindvall C, Wright AA. Feasibility and acceptability of a nurse-led telehealth intervention (BOLSTER) to support patients with peritoneal carcinomatosis and their caregivers: A pilot randomized clinical trial. Gynecol Oncol 2024; 188:1-7. PubMed
  • Davis J, Van Bulck L, Durieux BN, Lindvall C. The Temperature Feature of ChatGPT: Modifying Creativity for Clinical Research. JMIR Hum Factors 2024; 11:e53559. PubMed
  • Zupanc SN, Durieux BN, Walling AM, Lindvall C. Bolstering Advance Care Planning Measurement Using Natural Language Processing. J Palliat Med 2024. PubMed
  • Holdsworth LM, Giannitrapani K, Gamboa RC, O'Hanlon C, Singh N, Walling A, Lindvall C, Lorenz K. Role matters in understanding 'quality' in palliative care: a qualitative analysis of patient, caregiver and practitioner perspectives. BMJ Open 2024; 14:e076768. PubMed
  • Agaronnik ND, Streid JL, Kwok A, Schoenfeld AJ, Cooper Z, Lindvall C. Assessing performance of Geriatric Surgery Verification Program preoperative communication standards in spine surgery. J Am Geriatr Soc 2024. PubMed
  • Ramaswamy A, Hung M, Pelt J, Iranmahboub P, Calderon LP, Scherr IS, Wang G, Green D, Patel N, McClure TD, Barbieri C, Hu JC, Lindvall C, Scherr DS. Ascertaining provider-level implicit bias in electronic health records with rules-based natural language processing: A pilot study in the case of prostate cancer. PLoS ONE 2024; 19:e0314989. PubMed
  • Volandes AE, Zupanc SN, Lakin JR, Cabral HJ, Burns EA, Carney MT, Lopez S, Itty J, Emmert K, Martin NJ, Cole T, Dobie A, Cucinotta T, Joel M, Caruso LB, Henault L, Dugas JN, Astone K, Winter M, Wang N, Davis AD, Garde C, Rodriguez PM, El-Jawahri A, Moseley ET, Das S, Sciacca K, Ramirez AM, Gromova V, Lambert S, Sanghani S, Lindvall C, Paasche-Orlow MK. Video Intervention and Goals-of-Care Documentation in Hospitalized Older Adults: The VIDEO-PCE Randomized Clinical Trial. JAMA Netw Open 2023; 6:e2332556. PubMed
  • Zupanc SN, Lakin JR, Volandes AE, Paasche-Orlow MK, Moseley ET, Gundersen DA, Das S, Penumarthy A, Martins-Welch D, Burns EA, Carney MT, Itty JE, Emmert K, Tulsky JA, Lindvall C. Forms or Free-Text? Measuring Advance Care Planning Activity Using Electronic Health Records. J Pain Symptom Manage 2023. PubMed
  • Tarbi EC, Durieux BN, Brain JM, Kwok A, Umeton R, Samineni S, Tulsky JA, Lindvall C. Measuring Palliative Care Communication via Telehealth: A Pilot Study. J Pain Symptom Manage 2023; 66:e155-e161. PubMed
  • Singh N, Giannitrapani KF, Gamboa RC, O'Hanlon CE, Fereydooni S, Holdsworth LM, Lindvall C, Walling AM, Lorenz KA. What Patients Facing Cancer and Caregivers Want From Communication in Times of Crisis: A Qualitative Study in the Early Months of the COVID-19 Pandemic. Am J Hosp Palliat Care 2023. PubMed
  • Durieux BN, Zverev SR, Tarbi EC, Kwok A, Sciacca K, Pollak KI, Tulsky JA, Lindvall C. Development of a keyword library for capturing PRO-CTCAE-focused "symptom talk" in oncology conversations. JAMIA Open 2023; 6:ooad009. PubMed
  • Streid JL, Lee KC, Bader AM, Jarman MP, Rosenthal RA, Cooper Z, Lindvall C. Shared Decision Making in the Geriatric Surgery Verification Program: Assessing Baseline Performance. J Pain Symptom Manage 2023. PubMed
  • Amonoo HL, Markovitz NH, Johnson PC, Kwok A, Dale C, Deary EC, Daskalakis E, Choe JJ, Yamin N, Gothoskar M, Cronin KG, Fernandez-Robles C, Pirl WF, Chen YB, Cutler C, Lindvall C, El-Jawahri A. Delirium and Healthcare Utilization in Patients Undergoing Hematopoietic Stem Cell Transplantation. Transplant Cell Ther 2023. PubMed
  • O'Hanlon CE, Giannitrapani KF, Gamboa RC, Walling AM, Lindvall C, Garrido M, Asch SM, Lorenz KA. Integrating Patient and Expert Perspectives to Conceptualize High-Quality Palliative Cancer Care for Symptoms in the US Veterans Health Administration: A Qualitative Study. Inquiry 2023; 60:469580231160374. PubMed
  • Huber MT, Ling DY, Rozen AS, Terauchi SY, Sharma P, Fleischer-Black J, Schoenherr LA, Hutchinson RN, Lindvall C, Jones CA, Guerry RT, Berlin A. Top Ten Tips Palliative Care Clinicians Should Know About Leveraging the Electronic Health Record for Data Collection and Quality Improvement. J Palliat Med 2022. PubMed
  • Bhatt S, Johnson PC, Markovitz NH, Gray T, Nipp RD, Ufere N, Rice J, Reynolds MJ, Lavoie MW, Clay MA, Lindvall C, El-Jawahri A. The Use of Natural Language Processing to Assess Social Support in Patients With Advanced Cancer. Oncologist 2022. PubMed
  • Hu FY, Tabata-Kelly M, Johnston FM, Walling AM, Lindvall C, Bernacki RE, Pusic AL, Cooper Z. Surgeon-reported Factors Influencing Adoption of Quality Standards for Goal-concordant Care in Patients with Advanced Cancer: A Qualitative Study. Ann Surg 2022. PubMed
  • Gray TF, Kwok A, Do KM, Zeng S, Moseley ET, Dbeis YM, Umeton R, Tulsky JA, El-Jawahri A, Lindvall C. Associations Between Family Member Involvement and Outcomes of Patients Admitted to the Intensive Care Unit: Retrospective Cohort Study. JMIR Med Inform 2022; 10:e33921. PubMed
  • Lindvall C, Deng CY, Agaronnik ND, Kwok A, Samineni S, Umeton R, Mackie-Jenkins W, Kehl KL, Tulsky JA, Enzinger AC. Deep Learning for Cancer Symptoms Monitoring on the Basis of Electronic Health Record Unstructured Clinical Notes. JCO Clin Cancer Inform 2022; 6:e2100136. PubMed
  • Volandes AE, Zupanc SN, Paasche-Orlow MK, Lakin JR, Chang Y, Burns EA, LaVine NA, Carney MT, Martins-Welch D, Emmert K, Itty JE, Moseley ET, Davis AD, El-Jawahri A, Gundersen DA, Fix GM, Yacoub AM, Schwartz P, Gabry-Kalikow S, Garde C, Fischer J, Henault L, Burgess L, Goldman J, Kwok A, Singh N, Alvarez Suarez AL, Gromova V, Jacome S, Tulsky JA, Lindvall C. Association of an Advance Care Planning Video and Communication Intervention With Documentation of Advance Care Planning Among Older Adults: A Nonrandomized Controlled Trial. JAMA Netw Open 2022; 5:e220354. PubMed
  • Lakin JR, Zupanc SN, Lindvall C, Moseley ET, Das S, Sciacca K, Cabral HJ, Burns EA, Carney MT, Itty J, Lopez S, Emmert K, Martin NJ, Lambert S, Polo J, Sanghani S, Dugas JN, Gomez M, Winter MR, Wang N, Gabry-Kalikow S, Dobie A, Amshoff M, Cucinotta T, Joel M, Caruso LB, Ramirez AM, Salerno K, Ogunneye Q, Henault L, Davis AD, Volandes A, Paasche-Orlow MK. .Study protocol for Video Images about Decisions to Improve Ethical Outcomes with Palliative Care Educators (VIDEO-PCE): a pragmatic stepped wedge cluster randomised trial of older patients admitted to the hospital BMJ Open 2022; 12:e065236. PubMed
  • Greer JA, Moy B, El-Jawahri A, Jackson VA, Kamdar M, Jacobsen J, Lindvall C, Shin JA, Rinaldi S, Carlson HA, Sousa A, Gallagher ER, Li Z, Moran S, Ruddy M, Anand MV, Carp JE, Temel JS. Randomized Trial of a Palliative Care Intervention to Improve End-of-Life Care Discussions in Patients With Metastatic Breast Cancer. J Natl Compr Canc Netw 2022; 20:136-143. PubMed
  • Johnson PC, Markovitz NH, Gray TF, Bhatt S, Nipp RD, Ufere N, Rice J, Reynolds MJ, Lavoie MW, Topping CEW, Clay MA, Lindvall C, El-Jawahri A. Association of Social Support With Overall Survival and Healthcare Utilization in Patients With Aggressive Hematologic Malignancies. J Natl Compr Canc Netw 2021. PubMed
  • O'Hanlon CE, Giannitrapani KF, Lindvall C, Gamboa RC, Canning M, Asch SM, Garrido MM, , Walling AM, Lorenz KA. Patient and Caregiver Prioritization of Palliative and End-of-Life Cancer Care Quality Measures. J Gen Intern Med 2021. PubMed
  • Lindvall C, Deng CY, Moseley E, Agaronnik N, El-Jawahri A, Paasche-Orlow MK, Lakin JR, Volandes A, Tulsky TAIJA. Natural Language Processing to Identify Advance Care Planning Documentation in a Multisite Pragmatic Clinical Trial. J Pain Symptom Manage 2021. PubMed
  • Huang K, Gray TF, Romero-Brufau S, Tulsky JA, Lindvall C. Using nursing notes to improve clinical outcome prediction in intensive care patients: A retrospective cohort study. J Am Med Inform Assoc 2021. PubMed
  • Lakin JR, Gundersen DA, Lindvall C, Paasche-Orlow MK, Tulsky JA, Brannen EN, Pollak KI, Kennedy D, McLeggon JA, Stout JJ, Volandes A, . A Yet Unrealized Promise: Structured Advance Care Planning Elements in the Electronic Health Record. J Palliat Med 2021. PubMed
  • O'Hanlon CE, Lindvall C, Giannitrapani KF, Garrido M, Ritchie C, Asch S, Gamboa RC, Canning M, Lorenz KA, Walling AM, . Expert Stakeholder Prioritization of Process Quality Measures to Achieve Patient- and Family-Centered Palliative and End-of-Life Cancer Care. J Palliat Med 2021. PubMed
  • Wen Z, Nair P, Deng CY, Lu XH, Moseley E, George N, Lindvall C, Li Y. Mining heterogeneous clinical notes by multi-modal latent topic model. PLoS ONE 2021; 16:e0249622. PubMed
  • Agaronnik ND, El-Jawahri A, Lindvall C, Iezzoni LI. Exploring the Process of Cancer Care for Patients With Pre-Existing Mobility Disability. JCO Oncol Pract 2021; 17:e53-e61. PubMed
  • Agaronnik N, Lindvall C, El-Jawahri A, He W, Iezzoni L. Use of Natural Language Processing to Assess Frequency of Functional Status Documentation for Patients Newly Diagnosed With Colorectal Cancer. JAMA Oncol 2020. PubMed
  • Lee RY, Brumback LC, Lober WB, Sibley J, Nielsen EL, Treece PD, Kross EK, Loggers ET, Fausto JA, Lindvall C, Engelberg RA, Curtis JR. Identifying Goals of Care Conversations in the Electronic Health Record Using Natural Language Processing and Machine Learning. J Pain Symptom Manage 2020. PubMed
  • O'Hanlon CE, Lindvall C, Lorenz KA, Giannitrapani KF, Garrido M, Asch SM, Wenger N, Malin J, Dy SM, Canning M, Gamboa RC, Walling AM. Measure Scan and Synthesis of Palliative and End-of-Life Process Quality Measures for Advanced Cancer. JCO Oncol Pract 2020. PubMed
  • Geerse OP, Lamas DJ, Bernacki RE, Sanders JJ, Paladino J, Berendsen AJ, Hiltermann TJN, Lindvall C, Fromme EK, Block SD. Adherence and Concordance between Serious Illness Care Planning Conversations and Oncology Clinician Documentation among Patients with Advanced Cancer. J Palliat Med 2020. PubMed
  • DeCamp M, Lindvall C. Latent bias and the implementation of artificial intelligence in medicine. J Am Med Inform Assoc 2020. PubMed
  • Agaronnik N, Lindvall C, El-Jawahri A, He W, Iezzoni L. Challenges of Developing a Natural Language Processing Method with Electronic Health Records to Identify Persons with Chronic Mobility Disability. Arch Phys Med Rehabil 2020. PubMed
  • O'Hanlon CE, Walling AM, Lindvall C. Shortlist of Quality Indicators for End-of-Life Cancer Care. JAMA Oncol 2020. PubMed
  • Waring J, Lindvall C, Umeton R. Automated machine learning: Review of the state-of-the-art and opportunities for healthcare. Artif Intell Med 2020; 104:101822. PubMed
  • Udelsman BV, Moseley ET, Sudore RL, Keating NL, Lindvall C. Deep Natural Language Processing Identifies Variation in Care Preference Documentation. J Pain Symptom Manage 2020. PubMed
  • Lakin JR, Brannen EN, Tulsky JA, Paasche-Orlow MK, Lindvall C, Chang Y, Gundersen DA, El-Jawahri A, Volandes A, . Advance Care Planning: Promoting Effective and Aligned Communication in the Elderly (ACP-PEACE): the study protocol for a pragmatic stepped-wedge trial of older patients with cancer. BMJ Open 2020; 10:e040999. PubMed
  • Brizzi K, Zupanc SN, Udelsman BV, Tulsky JA, Wright AA, Poort H, Lindvall C. Natural Language Processing to Assess Palliative Care and End-of-Life Process Measures in Patients With Breast Cancer With Leptomeningeal Disease. Am J Hosp Palliat Care 2019. PubMed
  • Udelsman BV, Lee KC, Lilley EJ, Chang DC, Lindvall C, Cooper Z. Variation in Serious Illness Communication among Surgical Patients Receiving Palliative Care. J Palliat Med 2019. PubMed
  • Lee KC, Udelsman BV, Streid J, Chang DC, Salim A, Livingston DH, Lindvall C, Cooper Z. Natural Language Processing Accurately Measures Adherence to Best Practice Guidelines for Palliative Care in Trauma. J Pain Symptom Manage 2019. PubMed
  • Udelsman BV, Lilley EJ, Qadan M, Chang DC, Lillemoe KD, Lindvall C, Cooper Z. Deficits in the Palliative Care Process Measures in Patients with Advanced Pancreatic Cancer Undergoing Operative and Invasive Nonoperative Palliative Procedures. Ann Surg Oncol 2019. PubMed
  • Poort H, Zupanc SN, Leiter RE, Wright AA, Lindvall C. Documentation of Palliative and End-of-Life Care Process Measures Among Young Adults Who Died of Cancer: A Natural Language Processing Approach. J Adolesc Young Adult Oncol 2019. PubMed
  • Udelsman B, Lee K, Qadan M, Lillemoe KD, Chang D, Lindvall C, Cooper Z. Management of Pneumoperitoneum: Role and Limits of Nonoperative Treatment. Ann Surg 2019. PubMed
  • Sanders JJ, Berrier AI, Nshuti L, Tulsky JA, Lindvall C. Differences by Race, Religiosity, and Mental Health in Preferences for Life-Prolonging Treatment Among Medicare Beneficiaries. J Gen Intern Med 2019. PubMed
  • Chua IS, Leiter RE, Brizzi KT, Coey CA, Mazzola E, Tulsky JA, Lindvall C. US National Trends in Opioid-Related Hospitalizations Among Patients With Cancer. JAMA Oncol 2019. PubMed
  • Udelsman BV, Corey KE, Lindvall C, Gee DW, Meireles OR, Hutter MM, Chang DC, Witkowski ER. Risk factors and prevalence of liver disease in review of 2557 routine liver biopsies performed during bariatric surgery. Surg Obes Relat Dis 2019. PubMed
  • Ouchi K, George N, Schuur JD, Aaronson EL, Lindvall C, Bernstein E, Sudore RL, Schonberg MA, Block SD, Tulsky JA. Goals-of-Care Conversations for Older Adults With Serious Illness in the Emergency Department: Challenges and Opportunities. Ann Emerg Med 2019. PubMed
  • Hu SY, Santus E, Forsyth AW, Malhotra D, Haimson J, Chatterjee NA, Kramer DB, Barzilay R, Tulsky JA, Lindvall C. Can machine learning improve patient selection for cardiac resynchronization therapy? PLoS ONE 2019; 14:e0222397. PubMed
  • Chan A, Chien I, Moseley E, Salman S, Kaminer Bourland S, Lamas D, Walling AM, Tulsky JA, Lindvall C. Deep learning algorithms to identify documentation of serious illness conversations during intensive care unit admissions. Palliat Med 2018. PubMed
  • Lindvall C, Lilley EJ, Zupanc SN, Chien I, Udelsman BV, Walling A, Cooper Z, Tulsky JA. Natural Language Processing to Assess End-of-Life Quality Indicators in Cancer Patients Receiving Palliative Surgery. J Palliat Med 2018. PubMed
  • Udelsman B, Chien I, Ouchi K, Brizzi K, Tulsky JA, Lindvall C. Needle in a Haystack: Natural Language Processing to Identify Serious Illness. J Palliat Med 2018. PubMed
  • Curtis JR, Sathitratanacheewin S, Starks H, Lee RY, Kross EK, Downey L, Sibley J, Lober W, Loggers ET, Fausto JA, Lindvall C, Engelberg RA. Using Electronic Health Records for Quality Measurement and Accountability in Care of the Seriously Ill: Opportunities and Challenges. J Palliat Med 2018; 21:S52-S60. PubMed
  • Forsyth AW, Barzilay R, Hughes KS, Lui D, Lorenz KA, Enzinger A, Tulsky JA, Lindvall C. Machine Learning Methods to Extract Documentation of Breast Cancer Symptoms From Electronic Health Records. J Pain Symptom Manage 2018. PubMed
  • Lilley EJ, Lindvall C, Lillemoe KD, Tulsky JA, Wiener DC, Cooper Z. Measuring Processes of Care in Palliative Surgery: A Novel Approach Using Natural Language Processing. Ann Surg 2017. PubMed
  • Zhang H, Barysauskas C, Rickerson E, Catalano P, Jacobson J, Dalby C, Lindvall C, Selvaggi K. The Intensive Palliative Care Unit: Changing Outcomes for Hospitalized Cancer Patients in an Academic Medical Center. J Palliat Med 2017; 20:285-289. PubMed
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