Photo of Omar Arnaout,  MD

Omar Arnaout, MD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 525-8135
Fax: (617) 713-3050

Omar Arnaout, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Associate Professor, Neurosurgery, Harvard Medical School
  • Assistant Professor, Neurological Surgery, Harvard Medical School
  • Attending, Neurosurgery, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Publications from Harvard Catalyst Profiles

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  • Gerstl JVE, Gupta S, Stenberg CE, Chabros J, Nonnenbroich LF, Lindberg R, Altshuler MS, Seaver D, Mooney MA, Frerichs KU, Smith TR, Arnaout O. From Operating Room to Courtroom: Analyzing Malpractice Trajectories in Cranial Neurosurgery. Neurosurgery 2024. PubMed
  • Chang C, Chavarro VS, Gerstl JVE, Blitz SE, Spanehl L, Dubinski D, Valdes PA, Tran LN, Gupta S, Esposito L, Mazzetti D, Gessler FA, Arnaout O, Smith TR, Friedman GK, Peruzzi P, Bernstock JD. Recurrent Glioblastoma-Molecular Underpinnings and Evolving Treatment Paradigms. Int J Mol Sci 2024. PubMed
  • Ginder CR, Suero-Abreu GA, Ghumman SS, Bergmark BA, Arnaout O, Giugliano RP. Emergent Coronary Thrombectomy for Acute Myocardial Infarction Immediately Following Craniotomy with Tumor Resection. Cardiol Ther 2024; 13:443-452. PubMed
  • Huang KT, Mehta NH, Gupta S, See AP, Arnaout O. Evaluation of the safety, accuracy, and helpfulness of the GPT-4.0 Large Language Model in neurosurgery. J Clin Neurosci 2024; 123:151-156. PubMed
  • Gupta S, Hoffman SE, Mehta NH, Hauser B, Altshuler M, Bernstock JD, Smith TR, Arnaout O, Laws ER. Elevated risk of recurrence and retreatment for silent pituitary adenomas. Pituitary 2024. PubMed
  • Rahman R, Trippa L, Lee EQ, Arrillaga-Romany I, Fell G, Touat M, McCluskey C, Wiley J, Gaffey S, Drappatz J, Welch MR, Galanis E, Ahluwalia MS, Colman H, Nabors LB, Hepel J, Elinzano H, Schiff D, Chukwueke UN, Beroukhim R, Nayak L, McFaline-Figueroa JR, Batchelor TT, Rinne ML, Kaley TJ, Lu-Emerson C, Mellinghoff IK, Bi WL, Arnaout O, Peruzzi PP, Haas-Kogan D, Tanguturi S, Cagney D, Aizer A, Doherty L, Lavallee M, Fisher-Longden B, Dowling S, Geduldig J, Watkinson F, Pisano W, Malinowski S, Ramkissoon S, Santagata S, Meredith DM, Chiocca EA, Reardon DA, Alexander BM, Ligon KL, Wen PY. Inaugural Results of the Individualized Screening Trial of Innovative Glioblastoma Therapy: A Phase II Platform Trial for Newly Diagnosed Glioblastoma Using Bayesian Adaptive Randomization. J Clin Oncol 2023. PubMed
  • Yearley AG, Chalif EJ, Gupta S, Chalif JI, Bernstock JD, Nawabi N, Arnaout O, Smith TR, Reardon DA, Laws ER. Metastatic pituitary tumors: an institutional case series. Pituitary 2023. PubMed
  • Youssef G, Rahman R, Bay C, Wang W, Lim-Fat MJ, Arnaout O, Bi WL, Cagney DN, Chang YS, Cloughesy TF, DeSalvo M, Ellingson BM, Flood TF, Gerstner ER, Gonzalez Castro LN, Guenette JP, Kim AE, Lee EQ, McFaline-Figueroa JR, Potter CA, Reardon DA, Huang RY, Wen PY. Evaluation of Standard Response Assessment in Neuro-Oncology, Modified Response Assessment in Neuro-Oncology, and Immunotherapy Response Assessment in Neuro-Oncology in Newly Diagnosed and Recurrent Glioblastoma. J Clin Oncol 2023; 41:3160-3171. PubMed
  • Emani S, Swaminathan A, Grobman B, Duvall JB, Lopez I, Arnaout O, Huang KT. Critically reading machine learning literature in neurosurgery: a reader's guide and checklist for appraising prediction models. Neurosurg Focus 2023; 54:E3. PubMed
  • Ibn Essayed W, Jarvis CA, Bernstock JD, Slingerland A, Albanese J, Friedman GK, Arnaout O, Baird L. Positioning Transclival Tumor-Treating Fields for the Treatment of Diffuse Intrinsic Pontine Gliomas. Life (Basel) 2023. PubMed
  • Segar DJ, Bernstock JD, Arnaout O, Bi WL, Friedman GK, Langer R, Traverso G, Rampersad SM. Modeling of intracranial tumor treating fields for the treatment of complex high-grade gliomas. Sci Rep 2023; 13:1636. PubMed
  • Hoffman SE, Gupta S, O'Connor M, Jarvis CA, Zhao M, Hauser BM, Bernstock JD, Murphy S, Raftery SM, Lane K, Chiocca EA, Arnaout O. Reduced time to imaging, length of stay, and hospital charges following implementation of a novel postoperative pathway for craniotomy. J Neurosurg 2023. PubMed
  • Karandikar PV, Suh L, Gerstl JVE, Blitz SE, Qu QR, Won SY, Gessler FA, Arnaout O, Smith TR, Peruzzi PP, Yang W, Friedman GK, Bernstock JD. Positioning SUMO as an immunological facilitator of oncolytic viruses for high-grade glioma. Front Cell Dev Biol 2023; 11:1271575. PubMed
  • Deng D, Hammoudeh L, Youssef G, Chen YH, Shin KY, Lim-Fat MJ, McFaline-Figueroa JR, Chukwueke UN, Tanguturi S, Reardon DA, Lee EQ, Nayak L, Bi WL, Arnaout O, Ligon KL, Wen PY, Rahman R. Evaluating hematologic parameters in newly diagnosed and recurrent glioblastoma: Prognostic utility and clinical trial implications of myelosuppression. 2023; 5:vdad083. PubMed
  • Segar DJ, Bernstock JD, Rampersad S, Linda Bi W, Arnaout O, Friedman GK, Chiocca EA. Intracranial stimulation for brain cancer-The case for implantable, intracranial tumor treating fields. 2023; 5:vdad100. PubMed
  • Gupta S, Nawabi NL, Emani S, Medeiros L, Bernstock JD, Duvall J, Ng P, Smith TR, Wen PY, Reardon DA, Arnaout O. An expanded role for surgery in grade 3 1p/19q co-deleted oligodendroglioma. 2023; 5:vdad046. PubMed
  • Raghu ALB, Chen JA, Valdes PA, Essayed W, Claus E, Arnaout O, Smith TR, Chiocca EA, Peruzzi PP, Bernstock JD. Cerebellar High-Grade Glioma: A Translationally Oriented Review of the Literature. Cancers (Basel) 2022. PubMed
  • Yearley AG, Blitz SE, Patel RV, Chan A, Baird LC, Friedman GK, Arnaout O, Smith TR, Bernstock JD. Machine Learning in the Classification of Pediatric Posterior Fossa Tumors: A Systematic Review. Cancers (Basel) 2022. PubMed
  • Boaro A, Kaczmarzyk JR, Kavouridis VK, Harary M, Mammi M, Dawood H, Shea A, Cho EY, Juvekar P, Noh T, Rana A, Ghosh S, Arnaout O. Deep neural networks allow expert-level brain meningioma segmentation and present potential for improvement of clinical practice. Sci Rep 2022; 12:15462. PubMed
  • Hulsbergen AFC, Lo YT, Awakimjan I, Kavouridis VK, Phillips JG, Smith TR, Verhoeff JJC, Yu KH, Broekman MLD, Arnaout O. Survival Prediction After Neurosurgical Resection of Brain Metastases: A Machine Learning Approach. Neurosurgery 2022. PubMed
  • Blitz SE, Kappel AD, Gessler FA, Klinger NV, Arnaout O, Lu Y, Peruzzi PP, Smith TR, Chiocca EA, Friedman GK, Bernstock JD. Tumor-Associated Macrophages/Microglia in Glioblastoma Oncolytic Virotherapy: A Double-Edged Sword. Int J Mol Sci 2022. PubMed
  • Lim-Fat MJ, Youssef GC, Touat M, Iorgulescu JB, Whorral S, Allen M, Rahman R, Chukwueke U, McFaline-Figueroa JR, Nayak L, Lee EQ, Batchelor TT, Arnaout O, Peruzzi PP, Chiocca EA, Reardon DA, Meredith D, Santagata S, Beroukhim R, Bi WL, Ligon KL, Wen PY. Clinical utility of targeted next generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making. 2021. PubMed
  • McAvoy M, Prieto PC, Kaczmarzyk JR, Fernández IS, McNulty J, Smith T, Yu KH, Gormley WB, Arnaout O. Classification of glioblastoma versus primary central nervous system lymphoma using convolutional neural networks. Sci Rep 2021; 11:15219. PubMed
  • Faulkner H, Arnaout O, Hoshide R, Young IM, Yeung JT, Sughrue ME, Teo C. The Surgical Resection of Brainstem Glioma: Outcomes and Prognostic Factors. World Neurosurg 2021; 146:e639-e650. PubMed
  • Tewarie IA, Senders JT, Kremer S, Devi S, Gormley WB, Arnaout O, Smith TR, Broekman MLD. Survival prediction of glioblastoma patients-are we there yet? A systematic review of prognostic modeling for glioblastoma and its clinical potential. Neurosurg Rev 2020. PubMed
  • Shi DD, Arnaout O, Bi WL, Buchbinder EI, Cagney DN, Insco ML, Liu D, Schoenfeld JD, Aizer AA. Severe Radiation Necrosis Refractory to Surgical Resection in Patients with Melanoma and Brain Metastases Managed with Ipilimumab/Nivolumab and Brain-Directed Stereotactic Radiation Therapy. World Neurosurg 2020; 139:226-231. PubMed
  • Senders JT, Cho LD, Calvachi P, McNulty JJ, Ashby JL, Schulte IS, Almekkawi AK, Mehrtash A, Gormley WB, Smith TR, Broekman MLD, Arnaout O. Automating Clinical Chart Review: An Open-Source Natural Language Processing Pipeline Developed on Free-Text Radiology Reports From Patients With Glioblastoma. JCO Clin Cancer Inform 2020; 4:25-34. PubMed
  • Kavouridis VK, Boaro A, Dorr J, Cho EY, Iorgulescu JB, Reardon DA, Arnaout O, Smith TR. Contemporary assessment of extent of resection in molecularly defined categories of diffuse low-grade glioma: a volumetric analysis. J Neurosurg 2019. PubMed
  • Senders JT, Staples P, Mehrtash A, Cote DJ, Taphoorn MJB, Reardon DA, Gormley WB, Smith TR, Broekman ML, Arnaout O. An Online Calculator for the Prediction of Survival in Glioblastoma Patients Using Classical Statistics and Machine Learning. Neurosurgery 2019. PubMed
  • Chang K, Beers AL, Bai HX, Brown JM, Ly KI, Li X, Senders JT, Kavouridis VK, Boaro A, Su C, Bi WL, Rapalino O, Liao W, Shen Q, Zhou H, Xiao B, Wang Y, Zhang PJ, Pinho MC, Wen PY, Batchelor TT, Boxerman JL, Arnaout O, Rosen BR, Gerstner ER, Yang L, Huang RY, Kalpathy-Cramer J. Automatic assessment of glioma burden: A deep learning algorithm for fully automated volumetric and bi-dimensional measurement. 2019. PubMed
  • Senders JT, Karhade AV, Cote DJ, Mehrtash A, Lamba N, DiRisio A, Muskens IS, Gormley WB, Smith TR, Broekman MLD, Arnaout O. Natural Language Processing for Automated Quantification of Brain Metastases Reported in Free-Text Radiology Reports. JCO Clin Cancer Inform 2019; 3:1-9. PubMed
  • Bi WL, Hosny A, Schabath MB, Giger ML, Birkbak NJ, Mehrtash A, Allison T, Arnaout O, Abbosh C, Dunn IF, Mak RH, Tamimi RM, Tempany CM, Swanton C, Hoffmann U, Schwartz LH, Gillies RJ, Huang RY, Aerts HJWL. Artificial intelligence in cancer imaging: Clinical challenges and applications. CA Cancer J Clin 2019; 69:127-157. PubMed
  • Zhou H, Chang K, Bai HX, Xiao B, Su C, Bi WL, Zhang PJ, Senders JT, Vallières M, Kavouridis VK, Boaro A, Arnaout O, Yang L, Huang RY. Machine learning reveals multimodal MRI patterns predictive of isocitrate dehydrogenase and 1p/19q status in diffuse low- and high-grade gliomas. J. Neurooncol. 2019. PubMed
  • Senders JT, Arnaout O, Karhade AV, Dasenbrock HH, Gormley WB, Broekman ML, Smith TR. Natural and Artificial Intelligence in Neurosurgery: A Systematic Review. Neurosurgery 2018; 83:181-192. PubMed
  • Sanusi O, Arnaout O, Rahme RJ, Horbinski C, Chandler JP. Surgical Resection and Adjuvant Radiation Therapy in the Treatment of Skull Base Chordomas. World Neurosurg 2018; 115:e13-e21. PubMed
  • Rahme RJ, Arnaout OM, Sanusi OR, Kesavabhotla K, Chandler JP. Endoscopic Approach to Clival Chordomas: The Northwestern Experience. World Neurosurg 2018; 110:e231-e238. PubMed
  • Senders JT, Staples PC, Karhade AV, Zaki MM, Gormley WB, Broekman MLD, Smith TR, Arnaout O. Machine Learning and Neurosurgical Outcome Prediction: A Systematic Review. World Neurosurg 2018; 109:476-486.e1. PubMed
  • Ahmed AK, Dawood HY, Arnaout OM, Laws ER, Smith TR. Presentation, Treatment, and Long-Term Outcome of Intrasellar Chordoma: A Pooled Analysis of Institutional, SEER (Surveillance Epidemiology and End Results), and Published Data. World Neurosurg 2018; 109:e676-e683. PubMed
  • Senders JT, Zaki MM, Karhade AV, Chang B, Gormley WB, Broekman ML, Smith TR, Arnaout O. An introduction and overview of machine learning in neurosurgical care. Acta Neurochir (Wien) 2018; 160:29-38. PubMed
  • Senders JT, Harary M, Stopa BM, Staples P, Broekman MLD, Smith TR, Gormley WB, Arnaout O. Information-Based Medicine in Glioma Patients: A Clinical Perspective. Comput Math Methods Med 2018; 2018:8572058. PubMed
  • Chang K, Bai HX, Zhou H, Su C, Bi WL, Agbodza E, Kavouridis VK, Senders JT, Boaro A, Beers AL, Zhang B, Capellini A, Liao W, Shen Q, Li X, Xiao B, Cryan J, Ramkissoon S, Ramkissoon L, Ligon KL, Wen PY, Bindra RS, Woo JH, Arnaout O, Gerstner E, Zhang PJ, Rosen B, Yang L, Huang RY, Kalpathy-Cramer J. Residual Convolutional Neural Network for Determination of IDH Status in Low- and High-grade Gliomas from MR Imaging. Clin Cancer Res 2017. PubMed
  • Olsen HE, Lynn GM, Valdes PA, Cerecedo Lopez CD, Ishizuka AS, Arnaout O, Bi WL, Peruzzi PP, Chiocca EA, Friedman GK, Bernstock JD. Therapeutic cancer vaccines for pediatric malignancies: advances, challenges, and emerging technologies. ; 3:vdab027. PubMed
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