Photo of Scott J. Swanson,  MD

Scott J. Swanson, MD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 525-7532
Fax: (617) 582-6171


sjswanson@bwh.harvard.edu

Scott J. Swanson, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Professor, Surgery, Harvard Medical School
  • Associate Chief of Surgery, Surgical Oncology, Dana-Farber Cancer Institute
  • Vice Chair, Cancer Affairs, Surgery, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

My research is focused on the better understanding of early stage lung cancer in terms of its biologic fingerprint as well as clinical behavior. I am overseeing the development of a comprehensive database that will link clinical variables with pathologic and biologic markers within the specific tumor of interest. Associated with this and on the national front, I was the Chair of the Thoracic Surgery Sub-Committee for CALGB prior to its integration with Alliance, an NCI-sponsored National Comprehensive Cancer Cooperative Group. in this role, I oversaw thoracic surgery protocols. Additionally, I serve on advisory boards to further the education, training, and advancement of minimally invasive thoracic surgery. I direct 4-6 courses per year that are given nationally to help advance the knowledge of this field.

I focus my clinical attention on the treatment of thoracic malignancies and in particular I apply minimally invasive and newer technologies to optimize treatment. I took on the leadership of the Minimally Invasive Thoracic Surgery program while continuing to advance the education and implementation of operations such as minimally invasive thoracoscopic lobectomy through national courses, the editing of The Atlas of Minimally Invasive Thoracic Surgery, and directing AATS focus courses on thoracic surgery; the most recent course was in Chengdu in November 2019.

My research integrates clinical data with the tumor pathology to better define prognostic variables. This should permit better treatment options for patients with lung cancer. I focus a significant amount of his clinical activity in further developing minimally invasive thoracic surgery both in terms of its breadth and depth at the hospital as well as spending approximately 30 hours per week teaching the residents and fellows on the service

Publications from Harvard Catalyst Profiles

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  • McAllister MA, Rochefort MM, Ugalde Figueroa P, Leo R, Sugarbaker EA, Singh A, Herrera-Zamora J, Barcelos RR, Mazzola E, Heiling H, Jaklitsch MT, Bueno R, Swanson SJ. Complete anatomic segmentectomy shows improved oncologic outcomes compared to incomplete anatomic segmentectomy. 2024. PubMed
  • Singh A, McAllister M, De León LE, Kücükak S, Rochefort MM, Mazzola E, Maldonado L, Hartigan PM, Jaklitsch MT, Swanson SJ, Bueno R, Deeb AL, Patil N. Liposomal bupivacaine intercostal block placed under direct vision reduces morphine use in thoracic surgery. J Thorac Dis 2024; 16:1161-1170. PubMed
  • Sun JD, Sugarbaker E, Byrne SC, Gagné A, Leo R, Swanson SJ, Hammer MM. Clinical Outcomes of Resected Pure Ground-Glass, Heterogeneous Ground-Glass, and Part-Solid Pulmonary Nodules. AJR Am J Roentgenol 2024. PubMed
  • Solomon D, Deeb AL, Tarabine K, Xie Y, Mazzola E, Zhao L, Hammer MM, Jaklitsch MT, Swanson SJ, Bueno R, Wee JO. Predicting outcomes in esophageal adenocarcinoma following neoadjuvant chemoradiation: interactions between tumor response and survival. J Thorac Cardiovasc Surg 2023. PubMed
  • Steimer D, Coughlin JM, Yates E, Xie Y, Mazzola E, Jaklitsch MT, Swanson SJ, Orgill D, Marshall MB. Empiric Flap Coverage for the Pneumonectomy Stump: How Protective Is It? A Single-Institution Cohort Study. J Thorac Cardiovasc Surg 2023. PubMed
  • Forde PM, Spicer J, Lu S, Provencio M, Mitsudomi T, Awad MM, Felip E, Broderick SR, Brahmer JR, Swanson SJ, Kerr K, Wang C, Ciuleanu TE, Saylors GB, Tanaka F, Ito H, Chen KN, Liberman M, Vokes EE, Taube JM, Dorange C, Cai J, Fiore J, Jarkowski A, Balli D, Sausen M, Pandya D, Calvet CY, Girard N. Plain language summary of the CheckMate 816 study results: nivolumab plus chemotherapy given before surgery for non-small-cell lung cancer. Future Oncol 2023. PubMed
  • Khalil HA, Shi W, Mazzola E, Lee DN, Norton-Hughes E, Dolan D, Corman S, White A, Sholl LM, Swanson SJ. Analysis of recurrence in lung adenocarcinoma with spread through air spaces. J Thorac Cardiovasc Surg 2023. PubMed
  • Swanson SJ, White A. Sublobar resections for lung cancer: Finally, some answers and some more questions? J Surg Oncol 2023; 127:269-274. PubMed
  • Dolan DP, Polhemus E, Lee DN, Mazzola E, Jaklitsch MT, Wee JO, Bueno R, Swanson SJ, White A. Hyperthermic intraoperative chemotherapy (HIOC) for Stage IVa thymic malignancy may improve 5-year disease-free survival. J Surg Oncol 2022. PubMed
  • Weiss KD, Deeb AL, Wee JO, Swanson SJ, Bueno R, Jaklitsch MT, Rochefort MM. When a segmentectomy is not a segmentectomy: Quality assurance audit and evaluation of required elements for an anatomic segmentectomy. J Thorac Cardiovasc Surg 2022. PubMed
  • Swanson SJ. Going Green: Efforts to understand and recommend new technology in thoracic surgery. Ann Thorac Surg 2022. PubMed
  • Dolan DP, Lee DN, Polhemus E, Kucukak S, De León LE, Wiener D, Jaklitsch MT, Swanson SJ, White A. Report on lung cancer surgery during COVID-19 pandemic at a high volume US institution. J Thorac Dis 2022; 14:2874-2879. PubMed
  • Dezube AR, Hirji S, Shah R, Axtell A, Rodriguez M, Swanson SJ, Jaklitsch MT, Mody GN. Pre-COVID-19 National Mortality Trends in Open and Video-Assisted Lobectomy for Non-Small Cell Lung Cancer. J Surg Res 2022; 274:213-223. PubMed
  • Dolan DP, Lee DN, Kucukak S, De León LE, Bueno R, Jaklitsch MT, Swanson SJ, White A. Salvage surgery for local recurrence after sublobar surgery in Stages I and II non-small cell lung cancer. J Surg Oncol 2022. PubMed
  • Forde PM, Spicer J, Lu S, Provencio M, Mitsudomi T, Awad MM, Felip E, Broderick SR, Brahmer JR, Swanson SJ, Kerr K, Wang C, Ciuleanu TE, Saylors GB, Tanaka F, Ito H, Chen KN, Liberman M, Vokes EE, Taube JM, Dorange C, Cai J, Fiore J, Jarkowski A, Balli D, Sausen M, Pandya D, Calvet CY, Girard N, . Neoadjuvant Nivolumab plus Chemotherapy in Resectable Lung Cancer. N Engl J Med 2022. PubMed
  • Dezube AR, Cooper L, Mazzola E, Dolan DP, Lee DN, Kucukak S, De Leon LE, Dumontier C, Ademola B, Polhemus E, Bueno R, White A, Swanson SJ, Jaklitsch MT, Frain L, Wee JO. Long-term Outcomes Following Esophagectomy in Older and Younger Adults with Esophageal Cancer. J Gastrointest Surg 2022. PubMed
  • Dezube AR, Cooper L, Mazzola E, Dolan DP, Lee DN, Kucukak S, De Leon LE, Dumontier C, White A, Swanson SJ, Jaklitsch MT, Frain LN, Wee JO, Ademola B, Polhemus E, . Perioperative Esophagectomy Outcomes in Older Esophageal Cancer Patients in Two Different Time Eras. Semin Thorac Cardiovasc Surg 2022. PubMed
  • Pennathur A, Brunelli A, Criner GJ, Keshavarz H, Mazzone P, Walsh G, Luketich J, Liptay M, Wafford QE, Murthy S, Marshall MB, Tong B, Lanuti M, Wolf A, Pettiford B, Loo BW, Merritt RE, Rocco G, Schuchert M, Varghese TK, Swanson SJ, . Definition and assessment of high risk in patients considered for lobectomy for stage I non-small cell lung cancer: The American Association for Thoracic Surgery expert panel consensus document. J Thorac Cardiovasc Surg 2021; 162:1605-1618.e6. PubMed
  • Dolan D, White A, Lee DN, Mazzola E, Polhemus E, Kucukak S, Wee JO, Swanson SJ. Short and Long-term Outcomes Among High-Volume vs Low-Volume Esophagectomy Surgeons at a High-Volume Center. Semin Thorac Cardiovasc Surg 2021. PubMed
  • Beattie R, Furrer K, Dolan DP, Curioni-Fontecedro A, Lee DN, Frauenfelder T, Hoeller S, Weder W, Bueno R, Opitz I, Swanson S. Two centres experience of lung cancer resection in patients with advanced non-small cell lung cancer upon treatment with immune checkpoint inhibitors: safety and clinical outcomes. 2021. PubMed
  • Dolan DP, Swanson SJ, Lee DN, Polhemus E, Kucukak S, Wiener DC, Bueno R, Wee JO, White A. Esophagectomy for Esophageal Cancer Performed During the Early Phase of the COVID-19 Pandemic. Semin Thorac Cardiovasc Surg 2021. PubMed
  • Dolan D, Swanson SJ, Gill R, Lee DN, Mazzola E, Kucukak S, Polhemus E, Bueno R, White A. Survival and Recurrence Following Wedge Resection Versus Lobectomy for Early-Stage Non-Small Cell Lung Cancer. Semin Thorac Cardiovasc Surg 2021. PubMed
  • Dolan DP, Swanson SJ. The modern approach to esophagectomy-review of the shift towards minimally invasive surgery. Ann Transl Med 2021; 9:901. PubMed
  • Bravo-Iñiguez CE, He Z, Dezube AR, Mazzola E, Yelamanchili N, Zhao L, Bueno R, Swanson SJ, White A, Wiener DC, Jaklitsch MT, Wee JO. Impact of radial margins after esophagectomy for esophageal cancer. Eur J Surg Oncol 2021. PubMed
  • White A, Kucukak S, Lee DN, Mazzola E, Dolan D, Bueno R, Jaklitsch MT, Swanson SJ. Chemotherapy and surgical resection for N1 positive non-small cell lung cancer: Better than expected outcomes. Semin Thorac Cardiovasc Surg 2021. PubMed
  • Alden SL, Swanson SJ, Nishino M, Sholl LM, Awad MM. -Mutant Pulmonary Langerhans Cell Histiocytosis Mimicking Recurrence of Early-Stage -Mutant Lung Adenocarcinoma. JTO Clin Res Rep 2021; 2:100127. PubMed
  • White AA, Lee DN, Mazzola E, Kucukak S, Polhemus E, Jaklitsch MT, Mentzer SJ, Wee JO, Bueno R, Swanson SJ. Adjuvant therapy following induction therapy and surgery improves survival in N2-positive non-small cell lung cancer. J Surg Oncol 2021; 123:579-586. PubMed
  • Dolan DP, White A, Mazzola E, Lee DN, Gill R, Kucukak S, Bueno R, Jaklitsch MT, Mentzer SJ, Swanson SJ. Outcomes of superior segmentectomy versus lower lobectomy for superior segment Stage I non-small-cell lung cancer are equivalent: An analysis of 196 patients at a single, high volume institution. J Surg Oncol 2021; 123:570-578. PubMed
  • Lapidot M, Gill RR, Mazzola E, Freyaldenhoven S, Swanson SJ, Jaklitsch MT, Sugarbaker DJ, Bueno R. Pleurectomy Decortication in the Treatment of Malignant Pleural Mesothelioma: Encouraging Results and Novel Prognostic Implications Based on Experience in 355 Consecutive Patients. Ann Surg 2020. PubMed
  • Rodriguez M, Dezube AR, Bravo-Iniguez CE, Fox S, De León LE, Tarascio J, Freyaldenhoven S, Mentzer SJ, Swanson SJ, Bueno R, Rochefort MM, Marshall MB, Jaklitsch MT. Impact of Neoadjuvant Chemoradiation On Adverse Events Following Bronchial Sleeve Resection. Ann Thorac Surg 2020. PubMed
  • Bhagat R, Swanson SJ, Hammer MM, Mallidi HR, White A. Multimodality Curative Treatment of IIIA/T4 Lung Adenocarcinoma. Ann Thorac Surg 2020. PubMed
  • White A, Kucukak S, Lee DN, Bueno R, Jaklitsch M, Mentzer S, Sugarbaker D, Wee J, Swanson SJ. Completion pneumonectomy is safe and effective in select patients with recurrent non-small cell lung cancer. J Thorac Dis 2020; 12:217-222. PubMed
  • Bilgi Z, Swanson SJ. Current indications and outcomes for thoracoscopic segmentectomy for early stage lung cancer. J Thorac Dis 2019; 11:S1662-S1669. PubMed
  • White A, Kucukak S, Lee DN, Mazzola E, Zhang Y, Swanson SJ. Ivor Lewis minimally invasive esophagectomy for esophageal cancer: An excellent operation that improves with experience. J Thorac Cardiovasc Surg 2019; 157:783-789. PubMed
  • Hirji SA, Swanson SJ. T1a lung carcinoma: the place of segmentectomy in the treatment array. J Thorac Dis 2018; 10:S1151-S1156. PubMed
  • Yang H, Liu H, Chen Y, Zhu C, Fang W, Yu Z, Mao W, Xiang J, Han Y, Chen Z, Yang H, Wang J, Pang Q, Zheng X, Yang H, Li T, Lordick F, D'Journo XB, Cerfolio RJ, Korst RJ, Novoa NM, Swanson SJ, Brunelli A, Ismail M, Fernando HC, Zhang X, Li Q, Wang G, Chen B, Mao T, Kong M, Guo X, Lin T, Liu M, Fu J, . Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial. J Clin Oncol 2018; 36:2796-2803. PubMed
  • Mohiuddin K, Haneuse S, Sofer T, Gill R, Jaklitsch MT, Colson YL, Wee J, Bueno R, Mentzer SJ, Sugarbaker DJ, Swanson SJ. Relationship between margin distance and local recurrence among patients undergoing wedge resection for small (≤2 cm) non-small cell lung cancer. J Thorac Cardiovasc Surg 2014; 147:1169-75; discussion 1175-7. PubMed
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