Photo of Kathleen Lyons,  ScD

Kathleen Lyons, ScD

MGH Institute of Health Professions

MGH Institute of Health Professions
Phone: (617) 643-5372


KLyons2@mghihp.edu

Photo of Kathleen Lyons,  ScD

MGH Institute of Health Professions
Phone: (617) 643-5372


KLyons2@mghihp.edu

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Kathleen Lyons, ScD

MGH Institute of Health Professions

EDUCATIONAL TITLES

  • Professor, Occupational Therapy, MGH Institute of Health Professions
  • Research Associate, Physical Medicine and Rehabilitation, Harvard Medical School

HCC PROGRAM AFFILIATION

Research Abstract

In my research, I use my expertise in occupational therapy theory and practice to develop treatments to better target and ameliorate difficulties that adult cancer survivors face when engaging in daily activities within the home and community. I lead studies developing and testing interventions that directly target disability and foster full participation in meaningful activities. My approach to intervention development is informed by my training in implementation science and mixed methods research.

I spent 18 years conducting behavioral intervention development research at Dartmouth College within an interdisciplinary team. I completed my career development award in 2018 and initiated three other pilot studies while pursuing my first R01 (awarded in 2019; R01CA225792). I recently left Dartmouth to join the faculty at Massachusetts General Hospital Institute of Health Professions where I had the opportunity to establish the Cancer Rehabilitation (CaRe) laboratory.

My post-doctoral fellowship and career development award both involved training in experimental methods and developing and testing an intervention to reduce disability for older adult cancer survivors. As part of my career development award, I completed the NIH Training Institute for Dissemination and Implementation Research in Health in 2018. I applied those skills as the project principal investigator and lead author for two global health studies internally funded by the Norris Cotton Cancer Center (NCCC) at Dartmouth. Since leaving Dartmouth, I have maintained my role as the implementation science methodologist for the global health team at NCCC; we are now conducting a study to identify and characterize implementation strategies utilized during the COVID-19 pandemic to maintain radiation treatment for cancer patients in Central America. I am also currently a Co-investigator on a full scale randomized controlled trial (RCT) of two implementation strategies to explore their effectiveness in promoting uptake of early palliative care within community oncology practices. My role on that project is to facilitate a learning collaborative to help oncology practices implement the evidence-based palliative care intervention that our team developed fifteen years ago.

Throughout the intervention development and testing process, I use qualitative methods to elicit and incorporate stakeholder feedback regarding research priorities and the interventions we test. I completed coursework in qualitative analysis during all phases of my graduate work and was mentored by a medical anthropologist during my career development award. In turn, I have served on the dissertation committees of four students conducting qualitative studies. I have designed and conducted studies using qualitative data collection methods including participant observation, interview, and videotape analysis and analysis techniques of content analysis, thematic analysis, and Delphi procedures, resulting in 19 publications. Many of those studies have employed mixed methods, integrating both qualitative and quantitative data to describe concepts.

In summary, I have been a principal investigator or co-investigator for studies all along the intervention development pipeline. My team science has ranged from efficacy to implementation studies regarding early palliative care for people living with advanced cancer. My own line of inquiry ranges from descriptive to feasibility to efficacy studies of cancer rehabilitation approaches. I am committed to studying ways to maximize quality of life and minimize disability in people living with or recovering from cancer.

Publications from Harvard Catalyst Profiles

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  • Coss D, Bass JD, Lyons KD. Activity Engagement after Cancer in Community-Based Survivors. Occup Ther Health Care 2022; 36:141-151. PubMed
  • Brick R, Turner R, Bender C, Douglas M, Eilers R, Ferguson R, Leland N, Lyons KD, Toto P, Skidmore E. Impact of non-pharmacological interventions on activity limitations and participation restrictions in older breast cancer survivors: A scoping review. 2022; 13:132-142. PubMed
  • Stout NL, Santa Mina D, Lyons KD, Robb K, Silver JK. A systematic review of rehabilitation and exercise recommendations in oncology guidelines. CA Cancer J Clin 2021; 71:149-175. PubMed
  • Lyons KD, Slaughenhaupt RM, Mupparaju SH, Lim JS, Anderson AA, Stankovic AS, Cowan DR, Fellows AM, Binsted KA, Buckey JC. Autonomous Psychological Support for Isolation and Confinement. Aerosp Med Hum Perform 2020; 91:876-885. PubMed
  • Lyons KD, Padgett LS, Marshall TF, Greer JA, Silver JK, Raj VS, Zucker DS, Fu JB, Pergolotti M, Sleight AG, Alfano CM. Follow the trail: Using insights from the growth of palliative care to propose a roadmap for cancer rehabilitation. CA Cancer J Clin 2018. PubMed
  • Lyons KD, Li HH, Mader EM, Stewart TM, Morley CP, Formica MK, Perrapato SD, Seigne JD, Hyams ES, Irwin BH, Mosher T, Hegel MT. Cognitive and Affective Representations of Active Surveillance as a Treatment Option for Low-Risk Prostate Cancer. Am J Mens Health 2017; 11:63-72. PubMed
  • Dionne-Odom JN, Azuero A, Lyons KD, Hull JG, Prescott AT, Tosteson T, Frost J, Dragnev KH, Bakitas MA. Family Caregiver Depressive Symptom and Grief Outcomes From the ENABLE III Randomized Controlled Trial. J Pain Symptom Manage 2016; 52:378-85. PubMed
  • Dionne-Odom JN, Azuero A, Lyons KD, Hull JG, Tosteson T, Li Z, Li Z, Frost J, Dragnev KH, Akyar I, Hegel MT, Bakitas MA. Benefits of Early Versus Delayed Palliative Care to Informal Family Caregivers of Patients With Advanced Cancer: Outcomes From the ENABLE III Randomized Controlled Trial. J Clin Oncol 2015; 33:1446-52. PubMed
  • Bakitas MA, Tosteson TD, Li Z, Lyons KD, Hull JG, Li Z, Dionne-Odom JN, Frost J, Dragnev KH, Hegel MT, Azuero A, Ahles TA. Early Versus Delayed Initiation of Concurrent Palliative Oncology Care: Patient Outcomes in the ENABLE III Randomized Controlled Trial. J Clin Oncol 2015; 33:1438-45. PubMed
  • Lyons KD, Svensborn IA, Kornblith AB, Hegel MT. A Content Analysis of Functional Recovery Strategies of Breast Cancer Survivors. OTJR (Thorofare N J) 2015; 35:73-80. PubMed
  • Lyons KD, Hull JG, Kaufman PA, Li Z, Seville JL, Ahles TA, Kornblith AB, Hegel MT. Development and initial evaluation of a telephone-delivered, behavioral activation, and problem-solving treatment program to address functional goals of breast cancer survivors. J Psychosoc Oncol 2015; 33:199-218. PubMed
  • Lyons KD, Erickson KS, Hegel MT. Problem-solving strategies of women undergoing chemotherapy for breast cancer. Can J Occup Ther 2012; 79:33-40. PubMed
  • Hegel MT, Lyons KD, Hull JG, Kaufman P, Urquhart L, Li Z, Ahles TA. Feasibility study of a randomized controlled trial of a telephone-delivered problem-solving-occupational therapy intervention to reduce participation restrictions in rural breast cancer survivors undergoing chemotherapy. 2011; 20:1092-101. PubMed
  • Dionne-Odom JN, Lyons KD, Akyar I, Bakitas MA. Coaching Family Caregivers to Become Better Problem Solvers When Caring for Persons with Advanced Cancer. J Soc Work End Life Palliat Care ; 12:63-81. PubMed
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