Photo of Christopher Manz, MD

Christopher Manz, MD

Dana-Farber Cancer Institute

Dana-Farber Cancer Institute
Phone: (617) 632-3315


christopher_manz@dfci.harvard.edu

Photo of Christopher Manz, MD

Dana-Farber Cancer Institute
Phone: (617) 632-3315


christopher_manz@dfci.harvard.edu

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Christopher Manz, MD

Dana-Farber Cancer Institute

EDUCATIONAL TITLES

  • Assistant Professor, Medicine, Harvard Medical School
  • Instructor, Medicine, Brigham And Women's Hospital
  • Instructor, Medicine, Dana-Farber Cancer Institute

HCC PROGRAM AFFILIATION

Research Abstract

Dr. Christopher Manz completed his internal medicine internship and residency in 2015, his fellowship in medical oncology in 2020 and his master’s in the science of health policy research in 2020, all at the University of Pennsylvania. Since 2020, he has been a medical oncologist at the Dana-Farber Cancer Institute and Brigham and Women’s Hospital where he specializes in the treatment of patients with gastrointestinal cancers.

He conducts health services research mostly aimed at improving cancer care quality while improving disparities in cancer outcomes, particularly for patients who have experienced incarceration. He has also developed novel mechanisms to promote communication between patients and their oncology team to improve goal-concordant, high-quality care near the end of life. Finally, he conducts research that examines the way that health care policy, particularly payment policy, influences cancer disparities and how such policies can be modified to improve health equity.

Publications from Harvard Catalyst Profiles

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  • Manz CR, Barnett ML. Are linchpin oncologists keeping the wheels from falling off cancer care? Journal of the National Cancer Institute 2023. PubMed
  • Sedhom R, Tomita-Barber J, Manz CR, Parikh RB, Gupta A, Hussaini Q, Dougherty D. Creating a culture for change: Lessons from behavioral economics and complexity science to increase serious illness conversations for patients with cancer. Curr Probl Cancer 2023. PubMed
  • Parikh RB, Schriver E, Ferrell WJ, Wakim J, Williamson J, Khan N, Kopinsky M, Balachandran M, Gabriel PE, Schuchter LM, Patel MS, Shulman LN, Manz CR. Remote Patient-Reported Outcomes and Activity Monitoring to Improve Patient-Clinician Communication Regarding Symptoms and Functional Status: A Randomized Controlled Trial. JCO Oncol Pract 2023. PubMed
  • Manz CR, Odayar VS, Schrag D. Cancer Screening Rates and Outcomes for Justice-Involved Individuals: A Scoping Review. J Correct Health Care 2023; 29:220-231. PubMed
  • Ramaswamy M, Manz C, Kouyoumdjian F, Vest N, Puglisi L, Wang E, Salyer C, Osei B, Zaller N, Rebbeck TR. Cancer equity for those impacted by mass incarceration. Journal of the National Cancer Institute 2023. PubMed
  • Manz CR, Zhang Y, Chen K, Long Q, Small DS, Evans CN, Chivers C, Regli SH, Hanson CW, Bekelman JE, Braun J, Rareshide CAL, O'Connor N, Kumar P, Schuchter LM, Shulman LN, Patel MS, Parikh RB. Long-term Effect of Machine Learning-Triggered Behavioral Nudges on Serious Illness Conversations and End-of-Life Outcomes Among Patients With Cancer: A Randomized Clinical Trial. JAMA Oncol 2023. PubMed
  • Huffman BM, Basu Mallick A, Horick NK, Wang-Gillam A, Hosein PJ, Morse MA, Beg MS, Murphy JE, Mavroukakis S, Zaki A, Schlechter BL, Sanoff H, Manz C, Wolpin BM, Arlen P, Lacy J, Cleary JM. Effect of a MUC5AC Antibody (NPC-1C) Administered With Second-Line Gemcitabine and Nab-Paclitaxel on the Survival of Patients With Advanced Pancreatic Ductal Adenocarcinoma: A Randomized Clinical Trial. JAMA Netw Open 2023; 6:e2249720. PubMed
  • Manz CR, Tramontano AC, Uno H, Parikh RB, Bekelman JE, Schrag D. Association of Oncologist Participation in Medicare's Oncology Care Model With Patient Receipt of Novel Cancer Therapies. JAMA Netw Open 2022; 5:e2234161. PubMed
  • Parikh RB, Manz CR, Nelson MN, Ferrell W, Belardo Z, Temel JS, Patel MS, Shea JA. Oncologist Perceptions of Algorithm-Based Nudges to Prompt Early Serious Illness Communication: A Qualitative Study. J Palliat Med 2022. PubMed
  • Stavrou E, Qiu J, Zafar A, Tramontano AC, Isakoff S, Winer E, Schrag D, Manz C. Breast Medical Oncologists' Perspectives of Telemedicine for Breast Cancer Care: A Survey Study. JCO Oncol Pract 2022. PubMed
  • Parikh RB, Manz CR, Nelson MN, Evans CN, Regli SH, O'Connor N, Schuchter LM, Shulman LN, Patel MS, Paladino J, Shea JA. Clinician perspectives on machine learning prognostic algorithms in the routine care of patients with cancer: a qualitative study. Support Care Cancer 2022; 30:4363-4372. PubMed
  • Li EH, Ferrell W, Klaiman T, Kumar P, O'Connor N, Schuchter LM, Chen J, Patel MS, Manz CR, Parikh RB. Impact of Behavioral Nudges on the Quality of Serious Illness Conversations Among Patients With Cancer: Secondary Analysis of a Randomized Controlled Trial. JCO Oncol Pract 2022; 18:e495-e503. PubMed
  • Li E, Manz C, Liu M, Chen J, Chivers C, Braun J, Schuchter LM, Kumar P, Patel MS, Shulman LN, Parikh RB. Oncologist phenotypes and associations with response to a machine learning-based intervention to increase advance care planning: Secondary analysis of a randomized clinical trial. PLoS ONE 2022; 17:e0267012. PubMed
  • Parikh RB, Ferrell W, Wakim J, Williamson J, Khan N, Kopinsky M, Balachandran M, Gabriel PE, Zhang Y, Schuchter LM, Shulman LN, Chen J, Patel MS, Manz CR. Patient and clinician nudges to improve symptom management in advanced cancer using patient-generated health data: study protocol for the PROStep randomised controlled trial. BMJ Open 2022; 12:e054675. PubMed
  • Manz CR, Odayar VS, Schrag D. Disparities in cancer prevalence, incidence, and mortality for incarcerated and formerly incarcerated patients: A scoping review. Cancer Med 2021; 10:7277-7288. PubMed
  • Doshi JA, Jahnke J, Raman S, Puckett JT, Brown VT, Ward MA, Li P, Manz CR. Treatment utilization patterns of newly initiated oral anticancer agents in a national sample of Medicare beneficiaries. J Manag Care Spec Pharm 2021; 27:1457-1468. PubMed
  • Manz CR, Parikh RB, Patel MS. Combining Machine Learning Predictive Algorithms With Behavioral Nudges to Increase Rates of Serious Illness Conversations in Patients With Cancer-Reply. JAMA Oncol 2021; 7:782. PubMed
  • Cotner CE, Balachandran M, Do D, Ferrell W, Khan N, Kopinsky M, McGettigan S, Morgan AU, Zinck L, Schuchter LM, Shulman LN, Asch DA, Manz CR, Parikh RB. Automated Text-Based Symptom Monitoring With Rapid Clinician Triage for Patients With Cancer and Suspected or Confirmed COVID-19. JCO Clin Cancer Inform 2021; 5:1134-1140. PubMed
  • Manz CR, Parikh RB, Small DS, Evans CN, Chivers C, Regli SH, Hanson CW, Bekelman JE, Rareshide CAL, O'Connor N, Schuchter LM, Shulman LN, Patel MS. Effect of Integrating Machine Learning Mortality Estimates With Behavioral Nudges to Clinicians on Serious Illness Conversations Among Patients With Cancer: A Stepped-Wedge Cluster Randomized Clinical Trial. JAMA Oncol 2020; 6:e204759. PubMed
  • Manz CR, Schrag D. Racial disparities in colorectal cancer recurrence and mortality: equitable care, inequitable outcomes? Journal of the National Cancer Institute 2020. PubMed
  • Manz CR, Chen J, Liu M, Chivers C, Regli SH, Braun J, Draugelis M, Hanson CW, Shulman LN, Schuchter LM, O'Connor N, Bekelman JE, Patel MS, Parikh RB. Validation of a Machine Learning Algorithm to Predict 180-Day Mortality for Outpatients With Cancer. JAMA Oncol 2020; 6:1723-1730. PubMed
  • Manz CR, Bekelman JE, Doshi JA. The Changing Characteristics of Technologies Covered by Medicare's New Technology Add-on Payment Program. JAMA Netw Open 2020; 3:e2012569. PubMed
  • Manz C, Rendle K, Bekelman J. Mind the gap: how vulnerable patients fall through the cracks of cancer quality metrics. BMJ Qual Saf 2020; 29:91-94. PubMed
  • Manz CR, Porter DL, Bekelman JE. Innovation and Access at the Mercy of Payment Policy: The Future of Chimeric Antigen Receptor Therapies. J Clin Oncol 2020; 38:384-387. PubMed
  • Parikh RB, Manz C, Chivers C, Regli SH, Braun J, Draugelis ME, Schuchter LM, Shulman LN, Navathe AS, Patel MS, O'Connor NR. Machine Learning Approaches to Predict 6-Month Mortality Among Patients With Cancer. JAMA Netw Open 2019; 2:e1915997. PubMed
  • Manz C, Ross JS, Grande D. Marketing to physicians in a digital world. N Engl J Med 2014; 371:1857-9. PubMed
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