Photo of David M. Miller,  MD, PhD

David M. Miller, MD, PhD

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 726-2667


dmiller4@mgh.harvard.edu

David M. Miller, MD, PhD

Massachusetts General Hospital

EDUCATIONAL TITLES

  • Assistant Professor, Medicine, Harvard Medical School
  • Assistant Professor, Dermatology, Harvard Medical School
  • Clinical Assistant, Medicine, Massachusetts General Hospital

DF/HCC PROGRAM AFFILIATION

Publications from Harvard Catalyst Profiles

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  • Gross ND, Miller DM, Khushalani NI, Divi V, Ruiz ES, Lipson EJ, Meier F, Su YB, Swiecicki PL, Atlas J, Geiger JL, Hauschild A, Choe JH, Hughes BGM, Schadendorf D, Patel VA, Homsi J, Taube JM, Lim AM, Ferrarotto R, Yoo SY, Mathias M, Han H, Seebach F, Lowy I, Fury MG, Rischin D. Neoadjuvant cemiplimab and surgery for stage II-IV cutaneous squamous-cell carcinoma: follow-up and survival outcomes of a single-arm, multicentre, phase 2 study. Lancet Oncol. 2023; 24:1196-1205. PubMed
  • Granger EE, Silk AW, Sharma NS, Groover MK, Guenette JP, Emerick KS, Miller DM, Krause KA, Ruiz ES. Leptomeningeal carcinomatosis from a recurrent cutaneous squamous cell carcinoma with perineural invasion in a lung transplant patient. JAAD Case Rep 2023; 37:61-63. PubMed
  • Miller DM, Shalhout SZ. StoryboardR: an R package and Shiny application designed to visualize real-world data from clinical patient registries. JAMIA Open 2023; 6:ooac109. PubMed
  • Miller DM, Emerick KS. Skin-Cancer Chemoprevention in Transplant Recipients. N Engl J Med 2023; 388:844-846. PubMed
  • Sun Y, Revach OY, Anderson S, Kessler EA, Wolfe CH, Jenney A, Mills CE, Robitschek EJ, Davis TGR, Kim S, Fu A, Ma X, Gwee J, Tiwari P, Du PP, Sindurakar P, Tian J, Mehta A, Schneider AM, Yizhak K, Sade-Feldman M, LaSalle T, Sharova T, Xie H, Liu S, Michaud WA, Saad-Beretta R, Yates KB, Iracheta-Vellve A, Spetz JKE, Qin X, Sarosiek KA, Zhang G, Kim JW, Su MY, Cicerchia AM, Rasmussen MQ, Klempner SJ, Juric D, Pai SI, Miller DM, Giobbie-Hurder A, Chen JH, Pelka K, Frederick DT, Stinson S, Ivanova E, Aref AR, Paweletz CP, Barbie DA, Sen DR, Fisher DE, Corcoran RB, Hacohen N, Sorger PK, Flaherty KT, Boland GM, Manguso RT, Jenkins RW. Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature 2023. PubMed
  • Shalhout SZ, Miller DM, Emerick KS, Kaufman HL. Therapy with oncolytic viruses: progress and challenges. Nat Rev Clin Oncol 2023. PubMed
  • Gross ND, Miller DM, Khushalani NI, Divi V, Ruiz ES, Lipson EJ, Meier F, Su YB, Swiecicki PL, Atlas J, Geiger JL, Hauschild A, Choe JH, Hughes BGM, Schadendorf D, Patel VA, Homsi J, Taube JM, Lim AM, Ferrarotto R, Kaufman HL, Seebach F, Lowy I, Yoo SY, Mathias M, Fenech K, Han H, Fury MG, Rischin D. Neoadjuvant Cemiplimab for Stage II to IV Cutaneous Squamous-Cell Carcinoma. N Engl J Med 2022; 387:1557-1568. PubMed
  • Shalhout SZ, Emerick KS, Kaufman HL, Silk AW, Thakuria M, Miller DM. A Retrospective Study of Ipilimumab Plus Nivolumab in Anti-PD-L1/PD-1 Refractory Merkel Cell Carcinoma. J Immunother 2022; 45:299-302. PubMed
  • Silk AW, Barker CA, Bhatia S, Bollin KB, Chandra S, Eroglu Z, Gastman BR, Kendra KL, Kluger H, Lipson EJ, Madden K, Miller DM, Nghiem P, Pavlick AC, Puzanov I, Rabinowits G, Ruiz ES, Sondak VK, Tavss EA, Tetzlaff MT, Brownell I. Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of nonmelanoma skin cancer. J Immunother Cancer 2022. PubMed
  • Miller DM, Shalhout SZ. BodyMapR: an R package and Shiny application designed to generate anatomical visualizations of cancer lesions. JAMIA Open 2022; 5:ooac013. PubMed
  • Shalhout SZ, Saqlain F, Wright K, Akinyemi O, Miller DM. Generalizable EHR-R-REDCap pipeline for a national multi-institutional rare tumor patient registry. JAMIA Open 2022; 5:ooab118. PubMed
  • Miller DM, Shalhout SZ, Casey D, Fashoyin-Aje L, Lemery S, Theoret MR, Pazdur R. Impact of an evolving regulatory landscape on skin cancer drug development in the U.S. Dermatol Online J 2022. PubMed
  • Shalhout SZ, Kaufman HL, Emerick KS, Miller DM. Immunotherapy for Nonmelanoma skin cancer: Facts and Hopes. Clin Cancer Res 2022. PubMed
  • Miller DM, Shalhout SZ, Saqlain F, Patel VA, Tsai KY, Elayavilli RK, Louv B, Brownell I, Wong MK. The Merkel Cell Carcinoma Patient Registry: From Promise to Prototype to Patient. J Registry Manag 2022; 49:4-9. PubMed
  • Shalhout SZ, Emerick K, Kaufman HL, Miller DM. Clinical utility of cell-free DNA liquid biopsies in Merkel cell carcinoma. Dermatol Online J 2021. PubMed
  • Saqlain F, Shalhout SZ, Wright K, Miller- DM. Evaluation of clinical characteristics and pre-biopsy impressions of primary Merkel cell carcinoma of the skin. Dermatol Online J 2021. PubMed
  • Saqlain F, Shalhout SZ, Emerick KS, Kaufman HL, Chen YE, Cusack JC, Wright K, Miller DM. Diagnostic yield of staging brain magnetic resonance imaging is low in Merkel cell carcinoma: A single-institution cohort study. J Am Acad Dermatol 2021. PubMed
  • Miller DM, Shalhout SZ. GENETEX-a GENomics Report TEXt mining R package and Shiny application designed to capture real-world clinico-genomic data. JAMIA Open 2021; 4:ooab082. PubMed
  • Saqlain F, Shalhout SZ, Wright K, Miller DM. Microsatellitosis in Merkel cell carcinoma: a staging quandary. Dermatol Online J 2021. PubMed
  • Shalhout SZ, Bloom R, Drake L, Miller DM. Evaluation of the fragility of pivotal trials used to support US Food and Drug Administration approval for plaque psoriasis. J Am Acad Dermatol 2021; 84:354-360. PubMed
  • Saqlain F, Shalhout SZ, Flaherty KT, Emerick KS, Miller DM. REDCap-Based Operational Tool to Guide Care Coordination in a Multidisciplinary Cutaneous Oncology Clinic. JCO Oncol Pract 2021. PubMed
  • Shalhout SZ, Park JC, Emerick KS, Sullivan RJ, Kaufman HL, Miller DM. Real-world assessment of response to anti-PD-1 therapy in advanced cutaneous squamous cell carcinoma. J Am Acad Dermatol 2021. PubMed
  • Shalhout SZ, Emerick KS, Kaufman HL, Miller DM. Immunotherapy for Non-melanoma Skin Cancer. Curr Oncol Rep 2021; 23:125. PubMed
  • Hoang MP, Donizy P, Wu CL, Kopczynski J, Pieniazek M, Miller DM, Ryś J. TdT Expression Is a Marker of Better Survival in Merkel Cell Carcinoma, and Expression of B-Cell Markers Is Associated With Merkel Cell Polyomavirus. Am J Clin Pathol 2020. PubMed
  • Ameri AH, Foreman RK, Vedak P, Chen S, Miller DM, Demehri S. Hypertrophic Lichen Planus with Histological Features of Squamous Cell Carcinoma Associated with Immune Checkpoint Blockade Therapy. Oncologist 2020. PubMed
  • Shalhout SZ, Emerick KS, Sadow PM, Linnoila JJ, Miller DM. Regionally Metastatic Merkel Cell Carcinoma Associated with Paraneoplastic Anti--methyl-D-aspartate Receptor Encephalitis. Case Rep Oncol Med 2020; 2020:1257587. PubMed
  • Saqlain F, Shalhout SZ, Emerick KS, Neilan TG, Sharova T, Miller DM. Metastatic Merkel Cell Carcinoma Masquerading as Multiple Immune-Related Adverse Events. Case Rep Dermatol Med 2020; 2020:8890845. PubMed
  • Macedo N, Miller DM, Haq R, Kaufman HL. Clinical landscape of oncolytic virus research in 2020. J Immunother Cancer 2020. PubMed
  • Shalhout SZ, Nahas MR, Drews RE, Miller DM. Generalized Acquired Cutis Laxa Associated with Monoclonal Gammopathy of Dermatological Significance. Case Rep Dermatol Med 2020; 2020:7480607. PubMed
  • Melms JC, Vallabhaneni S, Mills CE, Yapp C, Chen JY, Morelli E, Waszyk P, Kumar S, Deming D, Moret N, Rodriguez S, Subramanian K, Rogava M, Cartwright ANR, Luoma A, Mei S, Brinker TJ, Miller DM, Spektor A, Schadendorf D, Riggi N, Wucherpfennig KW, Sorger PK, Izar B. Inhibition of Haspin kinase promotes cell-intrinsic and extrinsic anti-tumor activity. Cancer Res 2019. PubMed
  • Miller DM, Trowbridge RM, Desai A, Drews RE. Kaposi's varicelliform eruption in a patient with metastatic melanoma and primary cutaneous anaplastic large cell lymphoma treated with talimogene laherparepvec and nivolumab. J Immunother Cancer 2018; 6:122. PubMed
  • Klebanov N, Gunasekera N, Lin WM, Hawryluk EB, Miller DM, Reddy BY, Christman MP, Beaulieu D, Rajadurai S, Duncan LM, Sober AJ, Tsao H. The Clinical Spectrum of Cutaneous Melanoma Morphology. J Am Acad Dermatol 2018. PubMed
  • Eliades P, Abraham BJ, Ji Z, Miller DM, Christensen CL, Kwiatkowski N, Kumar R, Njauw CN, Taylor M, Miao B, Zhang T, Wong KK, Gray NS, Young RA, Tsao H. High MITF Expression Is Associated with Super-Enhancers and Suppressed by CDK7 Inhibition in Melanoma. J Invest Dermatol 2018. PubMed
  • Miller DM, Faulkner-Jones BE, Stone JR, Drews RE. Complete pathologic response of metastatic cutaneous squamous cell carcinoma and allograft rejection after treatment with combination immune checkpoint blockade. JAAD Case Rep 2017; 3:412-415. PubMed
  • Shalhout SZ, Kaufman HL, Sullivan RJ, Lawrence D, Miller DM. Immune Checkpoint Inhibition in Marjolin Ulcer: A Case Series. J Immunother ; 44:234-238. PubMed
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