Ibrahim Chamseddine, PhD
Massachusetts General Hospital
Massachusetts General Hospital
Ibrahim Chamseddine, PhD
Massachusetts General Hospital
EDUCATIONAL TITLES
HCC PROGRAM AFFILIATION
Publications from Harvard Catalyst Profiles
- Thonglert K, Apisarnthanarax S, Yeap BY, Havard ME, Schaub SK, Nyflot MJ, Bowen SR, He Y, Tsai J, De BS, Chamseddine I, Pursley J, Roberts H, Wo J, Prayongrat A, Alisanant P, Amornwichet N, Khorprasert C, Hong T, Koay EJ, Grassberger C. Establishing Albumin-Bilirubin (ALBI) score changes as predictors of radiation-induced liver disease (RILD) in hepatocellular carcinoma (HCC) patients post external beam radiotherapy (EBRT). Int J Radiat Oncol Biol Phys 2025. PubMed
- Shah KD, Chamseddine I, Yuan X, Tian S, Qiu R, Zhou J, Dhabaan A, Al-Hallaq H, Yu DS, Paganetti H, Yang X. Clinically Interpretable Survival Risk Stratification in Head and Neck Cancer Using Bayesian Networks and Markov Blankets. Int J Radiat Oncol Biol Phys 2025. PubMed
- Cogno N, Shah KD, Ehret F, Beekman C, Enderling H, Dawson RJ, Bolch WE, Shih HA, Paganetti H, Chamseddine I. A mechanistic model of brain necrosis progression based on vascular heterogeneity. Int J Radiat Oncol Biol Phys 2025. PubMed
- Shah KD, Paganetti H, Yepes P, Hong TS, Wo JY, Roberts JH, Koay EJ, Guthier CV, Chamseddine I. Linear Federated Learning for Outcome Prediction With Application to Hepatocellular Carcinoma Radiotherapy. JCO Clin Cancer Inform 2025; 9:e2500074. PubMed
- Chamseddine I, Cowan C, Donnelly L, Abergel RJ, Schuemann J, Bertolet A, Maitz CA. Prognostic Role of Patient, Tumour and Radiomic Factors Influencing Outcomes in Dogs With Thyroid Cancer Treated With Iodine-131. Vet Comp Oncol 2025. PubMed
- Shah KD, Yeap BY, Lee H, Soetan ZO, Moteabbed M, Muise S, Cowan J, Remillard K, Silvia B, Mendenhall NP, Soffen E, Mishra MV, Kamran SC, Miyamoto DT, Paganetti H, Efstathiou JA, Chamseddine I. Predictive Model of Acute Rectal Toxicity in Prostate Cancer Treated With Radiotherapy. JCO Clin Cancer Inform 2025; 9:e2400252. PubMed
- Kunz LV, Bosque JJ, Nikmaneshi M, Chamseddine I, Munn LL, Schuemann J, Paganetti H, Bertolet A. AMBER: A Modular Model for Tumor Growth, Vasculature and Radiation Response. Bull. Math. Biol. 2024; 86:139. PubMed
- Chamseddine I, Shah K, Lee H, Ehret F, Schuemann J, Bertolet A, Shih HA, Paganetti H. Decoding Patient Heterogeneity Influencing Radiation-Induced Brain Necrosis. Clin Cancer Res 2024. PubMed
- Lalonde A, Bobić M, Sharp GC, Chamseddine I, Winey B, Paganetti H. Evaluating the effect of setup uncertainty reduction and adaptation to geometric changes on normal tissue complication probability using online adaptive head and neck intensity modulated proton therapy. Phys Med Biol 2023. PubMed
- Kim Y, Chamseddine I, Cho Y, Kim JS, Mohan R, Shusharina N, Paganetti H, Lin S, Yoon HI, Cho S, Grassberger C. Neural network based ensemble model to predict radiation induced lymphopenia after concurrent chemo-radiotherapy for non-small cell lung cancer from two institutions. Neoplasia 2023; 39:100889. PubMed
- Chamseddine I, Kim Y, De B, Naqa IE, Duda DG, Wolfgang JA, Pursley J, Wo JY, Hong TS, Paganetti H, Koay EJ, Grassberger C. Predictive Model of Liver Toxicity to Aid the Personalized Selection of Proton Versus Photon Therapy in Hepatocellular Carcinoma. Int J Radiat Oncol Biol Phys 2023. PubMed
- Bertolet A, Chamseddine I, Paganetti H, Schuemann J. The complexity of DNA damage by radiation follows a Gamma distribution: insights from the Microdosimetric Gamma Model. 2023; 13:1196502. PubMed
- Khalil A, Al Handawi K, Mohsen Z, Abdel Nour A, Feghali R, Chamseddine I, Kokkolaras M. Weekly Nowcasting of New COVID-19 Cases Using Past Viral Load Measurements. Viruses 2022. PubMed
- Kipouros T, Chamseddine I, Kokkolaras M. Using Parallel Coordinates in Optimization of Nano-Particle Drug Delivery. J Biomech Eng 2022. PubMed
- Cho Y, Kim Y, Chamseddine I, Lee WH, Kim HR, Lee IJ, Hong MH, Cho BC, Lee CG, Cho S, Kim JS, Yoon HI, Grassberger C. Lymphocyte dynamics during and after chemo-radiation correlate to dose and outcome in stage III NSCLC patients undergoing maintenance immunotherapy. Radiother Oncol 2022; 168:1-7. PubMed
- Chamseddine I, Kim Y, De B, El Naqa I, Duda DG, Wolfgang J, Pursley J, Paganetti H, Wo J, Hong T, Koay EJ, Grassberger C. Predictive Modeling of Survival and Toxicity in Patients With Hepatocellular Carcinoma After Radiotherapy. JCO Clin Cancer Inform 2022; 6:e2100169. PubMed
- Suveges S, Chamseddine I, Rejniak KA, Eftimie R, Trucu D. Collective Cell Migration in a Fibrous Environment: A Hybrid Multiscale Modelling Approach. Front Appl Math Stat 2021. PubMed
- Chamseddine IM, Kokkolaras M. A Dual Nanoparticle Delivery Strategy for Enhancing Drug Distribution in Cancerous Tissue. J Biomech Eng 2020. PubMed
- Chamseddine IM, Frieboes HB, Kokkolaras M. Multi-objective optimization of tumor response to drug release from vasculature-bound nanoparticles. Sci Rep 2020; 10:8294. PubMed
- Chamseddine IM, Rejniak KA. Hybrid modeling frameworks of tumor development and treatment. 2020; 12:e1461. PubMed
- Chamseddine IM, Frieboes HB, Kokkolaras M. Design Optimization of Tumor Vasculature-Bound Nanoparticles. Sci Rep 2018; 8:17768. PubMed
- Chamseddine IM, Kokkolaras M. Nanoparticle Optimization for Enhanced Targeted Anticancer Drug Delivery. J Biomech Eng 2018. PubMed