Photo of Ignacio Vazquez-Garcia, PhD

Ignacio Vazquez-Garcia, PhD

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 726-6256


ivazquez-garcia@mgh.harvard.edu

Photo of Ignacio Vazquez-Garcia, PhD

Massachusetts General Hospital
Phone: (617) 726-6256


ivazquez-garcia@mgh.harvard.edu

Visualize Collaborations

Ignacio Vazquez-Garcia, PhD

Massachusetts General Hospital

EDUCATIONAL TITLES

  • Assistant Professor, Pathology, Harvard Medical School
  • Assistant Investigator, Pathology, Massachusetts General Hospital
  • Assistant Investigator, Center for Cancer Research, Massachusetts General Hospital

HCC PROGRAM AFFILIATION

Research Abstract

The Vazquez-Garcia Lab studies fundamental principles of somatic evolution and immune surveillance in cancer. We focus on data-driven approaches to study cellular dynamics in tumors, combining single-cell genomics, cellular imaging and AI/ML approaches with large clinical datasets and experimental models. Our research draws on multi-modal data from basic science and clinical practice to understand how genomic adaptations confer selective advantages to tumor cells, act as biomarkers of therapeutic response and resistance, and sensitize tumors for targeted intervention. Our ultimate goal is to impact human health and clinical care for patients, leveraging our understanding of cancer trajectories to enable biomarkers and therapeutic strategies that anticipate and overcome tumor progression.

Publications from Harvard Catalyst Profiles

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  • Stur E, Peng F, Teng PN, Bayraktar E, Hu M, Corvigno S, Brown DJ, Lee S, Moore KN, Bateman NW, Darcy KM, Maxwell GL, P Conrads T, Sahni N, Vázquez-García I, Shah SP, Celestino J, D Fleming N, Navin NE, Wang L, Sood AK. The dynamic immune behavior of primary and metastatic ovarian carcinoma. NPJ Precis Oncol 2025; 9:120. PubMed
  • Vázquez-García I, Uhlitz F, Ceglia N, Lim JLP, Wu M, Mohibullah N, Niyazov J, Ruiz AEB, Boehm KM, Bojilova V, Fong CJ, Funnell T, Grewal D, Havasov E, Leung S, Pasha A, Patel DM, Pourmaleki M, Rusk N, Shi H, Vanguri R, Williams MJ, Zhang AW, Broach V, Chi DS, Da Cruz Paula A, Gardner GJ, Kim SH, Lennon M, Long Roche K, Sonoda Y, Zivanovic O, Kundra R, Viale A, Derakhshan FN, Geneslaw L, Issa Bhaloo S, Maroldi A, Nunez R, Pareja F, Stylianou A, Vahdatinia M, Bykov Y, Grisham RN, Liu YL, Lakhman Y, Nikolovski I, Kelly D, Gao J, Schietinger A, Hollmann TJ, Bakhoum SF, Soslow RA, Ellenson LH, Abu-Rustum NR, Aghajanian C, Friedman CF, McPherson A, Weigelt B, Zamarin D, Shah SP. Ovarian cancer mutational processes drive site-specific immune evasion. Nature 2022; 612:778-786. PubMed
  • Funnell T, O'Flanagan CH, Williams MJ, McPherson A, McKinney S, Kabeer F, Lee H, Salehi S, Vázquez-García I, Shi H, Leventhal E, Masud T, Eirew P, Yap D, Zhang AW, Lim JLP, Wang B, Brimhall J, Biele J, Ting J, Au V, Van Vliet M, Liu YF, Beatty S, Lai D, Pham J, Grewal D, Abrams D, Havasov E, Leung S, Bojilova V, Moore RA, Rusk N, Uhlitz F, Ceglia N, Weiner AC, Zaikova E, Douglas JM, Zamarin D, Weigelt B, Kim SH, Da Cruz Paula A, Reis-Filho JS, Martin SD, Li Y, Xu H, de Algara TR, Lee SR, Llanos VC, Huntsman DG, McAlpine JN, , Shah SP, Aparicio S. Single-cell genomic variation induced by mutational processes in cancer. Nature 2022; 612:106-115. PubMed
  • Boehm KM, Aherne EA, Ellenson L, Nikolovski I, Alghamdi M, Vázquez-García I, Zamarin D, Long Roche K, Liu Y, Patel D, Aukerman A, Pasha A, Rose D, Selenica P, Causa Andrieu PI, Fong C, Capanu M, Reis-Filho JS, Vanguri R, Veeraraghavan H, Gangai N, Sosa R, Leung S, McPherson A, Gao J, , Lakhman Y, Shah SP. Multimodal data integration using machine learning improves risk stratification of high-grade serous ovarian cancer. 2022; 3:723-733. PubMed
  • Hoyos D, Zappasodi R, Schulze I, Sethna Z, de Andrade KC, Bajorin DF, Bandlamudi C, Callahan MK, Funt SA, Hadrup SR, Holm JS, Rosenberg JE, Shah SP, Vázquez-García I, Weigelt B, Wu M, Zamarin D, Campitelli LF, Osborne EJ, Klinger M, Robins HS, Khincha PP, Savage SA, Balachandran VP, Wolchok JD, Hellmann MD, Merghoub T, Levine AJ, Łuksza M, Greenbaum BD. Fundamental immune-oncogenicity trade-offs define driver mutation fitness. Nature 2022; 606:172-179. PubMed
  • Dentro SC, Leshchiner I, Haase K, Tarabichi M, Wintersinger J, Deshwar AG, Yu K, Rubanova Y, Macintyre G, Demeulemeester J, Vázquez-García I, Kleinheinz K, Livitz DG, Malikic S, Donmez N, Sengupta S, Anur P, Jolly C, Cmero M, Rosebrock D, Schumacher SE, Fan Y, Fittall M, Drews RM, Yao X, Watkins TBK, Lee J, Schlesner M, Zhu H, Adams DJ, McGranahan N, Swanton C, Getz G, Boutros PC, Imielinski M, Beroukhim R, Sahinalp SC, Ji Y, Peifer M, Martincorena I, Markowetz F, Mustonen V, Yuan K, Gerstung M, Spellman PT, Wang W, Morris QD, Wedge DC, Van Loo P, . Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes. Cell 2021; 184:2239-2254.e39. PubMed
  • Liu YL, Selenica P, Zhou Q, Iasonos A, Callahan M, Feit NZ, Boland J, Vazquez-Garcia I, Mandelker D, Zehir A, Burger RA, Powell DJ, Friedman C, Cadoo K, Grisham R, Konner JA, O'Cearbhaill RE, Aghajanian C, Reis-Filho JS, Weigelt B, Zamarin D. Mutations, Homologous DNA Repair Deficiency, Tumor Mutational Burden, and Response to Immune Checkpoint Inhibition in Recurrent Ovarian Cancer. JCO Precis Oncol 2020. PubMed
  • Gerstung M, Jolly C, Leshchiner I, Dentro SC, Gonzalez S, Rosebrock D, Mitchell TJ, Rubanova Y, Anur P, Yu K, Tarabichi M, Deshwar A, Wintersinger J, Kleinheinz K, Vázquez-García I, Haase K, Jerman L, Sengupta S, Macintyre G, Malikic S, Donmez N, Livitz DG, Cmero M, Demeulemeester J, Schumacher S, Fan Y, Yao X, Lee J, Schlesner M, Boutros PC, Bowtell DD, Zhu H, Getz G, Imielinski M, Beroukhim R, Sahinalp SC, Ji Y, Peifer M, Markowetz F, Mustonen V, Yuan K, Wang W, Morris QD, , Spellman PT, Wedge DC, Van Loo P, . The evolutionary history of 2,658 cancers. Nature 2020; 578:122-128. PubMed
  • Campbell PJ, Getz G, Korbel JO, Stuart JM, Jennings JL, Stein LD, Perry MD, Nahal-Bose HK, Ouellette BFF, Li CH, Rheinbay E, Nielsen GP, Sgroi DC, Wu CL, Faquin WC, Deshpande V, Boutros PC, Lazar AJ, Hoadley KA, Louis DN, Dursi LJ, Yung CK, Bailey MH, Saksena G, Raine KM, Buchhalter I, Kleinheinz K, Schlesner M, Zhang J, Wang W, Wheeler DA, Ding L, Simpson JT, O'Connor BD, Yakneen S, Ellrott K, Miyoshi N, Butler AP, Royo R, Shorser SI, Vazquez M, Rausch T, Tiao G, Waszak SM, Rodriguez-Martin B, Shringarpure S, Wu DY, Demidov GM, Delaneau O, Hayashi S, Imoto S, Habermann N, Segre AV, Garrison E, Cafferkey A, Alvarez EG, Heredia-Genestar JM, Muyas F, Drechsel O, Bruzos AL, Temes J, Zamora J, Baez-Ortega A, Kim HL, Mashl RJ, Ye K, DiBiase A, Huang KL, Letunic I, McLellan MD, Newhouse SJ, Shmaya T, Kumar S, Wedge DC, Wright MH, Yellapantula VD, Gerstein M, Khurana E, Marques-Bonet T, Navarro A, Bustamante CD, Siebert R, Nakagawa H, Easton DF, Ossowski S, Tubio JMC, De La Vega FM, Estivill X, Yuen D, Mihaiescu GL, Omberg L, Ferretti V, Sabarinathan R, Pich O, Gonzalez-Perez A, Taylor-Weiner A, Fittall MW, Demeulemeester J, Tarabichi M, Roberts ND, Van Loo P, Cortés-Ciriano I, Urban L, Park P, Zhu B, Pitkänen E, Li Y, Saini N, Klimczak LJ, Weischenfeldt J, Sidiropoulos N, Alexandrov LB, Rabionet R, Escaramis G, Bosio M, Holik AZ, Susak H, Prasad A, Erkek S, Calabrese C, Raeder B, Harrington E, Mayes S, Turner D, Juul S, Roberts SA, Song L, Koster R, Mirabello L, Hua X, Tanskanen TJ, Tojo M, Chen J, Aaltonen LA, Rätsch G, Schwarz RF, Butte AJ, Brazma A, Chanock SJ, Chatterjee N, Stegle O, Harismendy O, Bova GS, Gordenin DA, Haan D, Sieverling L, Feuerbach L, Chalmers D, Joly Y, Knoppers B, Molnár-Gábor F, Phillips M, Thorogood A, Townend D, Goldman M, Fonseca NA, Xiang Q, Craft B, Piñeiro-Yáñez E, Muñoz A, Petryszak R, Füllgrabe A, Al-Shahrour F, Keays M, Haussler D, Weinstein J, Huber W, Valencia A, Papatheodorou I, Zhu J, Fan Y, Torrents D, Bieg M, Chen K, Chong Z, Cibulskis K, Eils R, Fulton RS, Gelpi JL, Gonzalez S, Gut IG, Hach F, Heinold M, Hu T, Huang V, Hutter B, Jäger N, Jung J, Kumar Y, Lalansingh C, Leshchiner I, Livitz D, Ma EZ, Maruvka YE, Milovanovic A, Nielsen MM, Paramasivam N, Pedersen JS, Puiggròs M, Sahinalp SC, Sarrafi I, Stewart C, Stobbe MD, Wala JA, Wang J, Wendl M, Werner J, Wu Z, Xue H, Yamaguchi TN, Yellapantula V, Davis-Dusenbery BN, Grossman RL, Kim Y, Heinold MC, Hinton J, Jones DR, Menzies A, Stebbings L, Hess JM, Rosenberg M, Dunford AJ, Gupta M, Imielinski M, Meyerson M, Beroukhim R, Reimand J, Dhingra P, Favero F, Dentro S, Wintersinger J, Rudneva V, Park JW, Hong EP, Heo SG, Kahles A, Lehmann KV, Soulette CM, Shiraishi Y, Liu F, He Y, Demircioğlu D, Davidson NR, Greger L, Li S, Liu D, Stark SG, Zhang F, Amin SB, Bailey P, Chateigner A, Frenkel-Morgenstern M, Hou Y, Huska MR, Kilpinen H, Lamaze FC, Li C, Li X, Li X, Liu X, Marin MG, Markowski J, Nandi T, Ojesina AI, Pan-Hammarström Q, Park PJ, Pedamallu CS, Su H, Tan P, Teh BT, Wang J, Xiong H, Ye C, Yung C, Zhang X, Zheng L, Zhu S, Awadalla P, Creighton CJ, Wu K, Yang H, Göke J, Zhang Z, Brooks AN, Fittall MW, Martincorena I, Rubio-Perez C, Juul M, Schumacher S, Shapira O, Tamborero D, Mularoni L, Hornshøj H, Deu-Pons J, Muiños F, Bertl J, Guo Q, Gonzalez-Perez A, Xiang Q, Bazant W, Barrera E, Al-Sedairy ST, Aretz A, Bell C, Betancourt M, Buchholz C, Calvo F, Chomienne C, Dunn M, Edmonds S, Green E, Gupta S, Hutter CM, Jegalian K, Jones N, Lu Y, Nakagama H, Nettekoven G, Planko L, Scott D, Shibata T, Shimizu K, Stratton MR, Yugawa T, Tortora G, VijayRaghavan K, Zenklusen JC, Townend D, Knoppers BM, Aminou B, Bartolome J, Boroevich KA, Boyce R, Buchanan A, Byrne NJ, Chen Z, Cho S, Choi W, Clapham P, Dow MT, Dursi LJ, Eils J, Farcas C, Fayzullaev N, Flicek P, Heath AP, Hofmann O, Hong JH, Hudson TJ, Hübschmann D, Ivkovic S, Jeon SH, Jiao W, Kabbe R, Kahles A, Kerssemakers JNA, Kim H, Kim J, Koscher M, Koures A, Kovacevic M, Lawerenz C, Liu J, Mijalkovic S, Mijalkovic-Lazic AM, Miyano S, Nastic M, Nicholson J, Ocana D, Ohi K, Ohno-Machado L, Pihl TD, Prinz M, Radovic P, Short C, Sofia HJ, Spring J, Struck AJ, Tijanic N, Vicente D, Wang Z, Williams A, Woo Y, Wright AJ, Yang L, Hamilton MP, Johnson TA, Kahraman A, Kellis M, Polak P, Sallari R, Sinnott-Armstrong N, von Mering C, Beltran S, Gerhard DS, Gut M, Trotta JR, Whalley JP, Niu B, Espiritu SMG, Gao S, Huang Y, Lalansingh CM, Teague JW, Wendl MC, Abascal F, Bader GD, Bandopadhayay P, Barenboim J, Brunak S, Carlevaro-Fita J, Chakravarty D, Chan CWY, Choi JK, Diamanti K, Fink JL, Frigola J, Gambacorti-Passerini C, Garsed DW, Haradhvala NJ, Harmanci AO, Helmy M, Herrmann C, Hobolth A, Hodzic E, Hong C, Isaev K, Izarzugaza JMG, Johnson R, Juul RI, Kim J, Kim JK, Jan Komorowski, Lanzós A, Larsson E, Lee D, Li S, Li X, Lin Z, Liu EM, Lochovsky L, Lou S, Madsen T, Marchal K, Martinez-Fundichely A, McGillivray PD, Meyerson W, Paczkowska M, Park K, Park K, Pons T, Pulido-Tamayo S, Reyes-Salazar I, Reyna MA, Rubin MA, Salichos L, Sander C, Schumacher SE, Shackleton M, Shen C, Shrestha R, Shuai S, Tsunoda T, Umer HM, Uusküla-Reimand L, Verbeke LPC, Wadelius C, Wadi L, Warrell J, Wu G, Yu J, Zhang J, Zhang X, Zhang Y, Zhao Z, Zou L, Lawrence MS, Raphael BJ, Bailey PJ, Craft D, Goldman MJ, Aburatani H, Binder H, Dinh HQ, Heath SC, Hoffmann S, Imbusch CD, Kretzmer H, Laird PW, Martin-Subero JI, Nagae G, Shen H, Wang Q, Weichenhan D, Zhou W, Berman BP, Brors B, Plass C, Akdemir KC, Bowtell DDL, Burns KH, Busanovich J, Chan K, Dueso-Barroso A, Edwards PA, Etemadmoghadam D, Haber JE, Jones DTW, Ju YS, Kazanov MD, Koh Y, Kumar K, Lee EA, Lee JJ, Lynch AG, Macintyre G, Markowetz F, Navarro FCP, Pearson JV, Rippe K, Scully R, Villasante I, Waddell N, Yang L, Yao X, Yoon SS, Zhang CZ, Bergstrom EN, Boot A, Covington K, Fujimoto A, Huang MN, Islam SMA, McPherson JR, Morganella S, Mustonen V, Ng AWT, Prokopec SD, Vázquez-García I, Wu Y, Yousif F, Yu W, Rozen SG, Rudneva VA, Shringarpure SS, Turner DJ, Xia T, Atwal G, Chang DK, Cooke SL, Faltas BM, Haider S, Kaiser VB, Karlić R, Kato M, Kübler K, Margolin A, Martin S, Nik-Zainal S, P'ng C, Semple CA, Smith J, Sun RX, Thai K, Wright DW, Yuan K, Biankin AV, Garraway L, Grimmond SM, Adams DJ, Anur P, Cao S, Christie EL, Cmero M, Cun Y, Dawson KJ, Dentro SC, Deshwar AG, Donmez N, Drews RM, Gerstung M, Ha G, Haase K, Jerman L, Ji Y, Jolly C, Lee J, Lee-Six H, Malikic S, Mitchell TJ, Morris QD, Oesper L, Peifer M, Peto M, Rosebrock D, Rubanova Y, Salcedo A, Sengupta S, Shi R, Shin SJ, Spiro O, Vembu S, Wintersinger JA, Yang TP, Yu K, Zhu H, Spellman PT, Weinstein JN, Chen Y, Fujita M, Han L, Hasegawa T, Komura M, Li J, Mizuno S, Shimizu E, Wang Y, Xu Y, Yamaguchi R, Yang F, Yang Y, Yoon CJ, Yuan Y, Liang H, Alawi M, Borozan I, Brewer DS, Cooper CS, Desai N, Grundhoff A, Iskar M, Su X, Zapatka M, Lichter P, Alsop K, Bruxner TJC, Christ AN, Cordner SM, Cowin PA, Drapkin R, Fereday S, George J, Hamilton A, Holmes O, Hung JA, Kassahn KS, Kazakoff SH, Kennedy CJ, Leonard CR, Mileshkin L, Miller DK, Arnau GM, Mitchell C, Newell F, Nones K, Patch AM, Quinn MC, Taylor DF, Thorne H, Traficante N, Vedururu R, Waddell NM, Waring PM, Wood S, Xu Q, deFazio A, Anderson MJ, Antonello D, Barbour AP, Bassi C, Bersani S, Cataldo I, Chantrill LA, Chiew YE, Chou A, Cingarlini S, Cloonan N, Corbo V, Davi MV, Duthie FR, Gill AJ, Graham JS, Harliwong I, Jamieson NB, Johns AL, Kench JG, Landoni L, Lawlor RT, Mafficini A, Merrett ND, Miotto M, Musgrove EA, Nagrial AM, Oien KA, Pajic M, Pinese M, Robertson AJ, Rooman I, Rusev BC, Samra JS, Scardoni M, Scarlett CJ, Scarpa A, Sereni E, Sikora KO, Simbolo M, Taschuk ML, Toon CW, Vicentini C, Wu J, Zeps N, Behren A, Burke H, Cebon J, Dagg RA, De Paoli-Iseppi R, Dutton-Regester K, Field MA, Fitzgerald A, Hersey P, Jakrot V, Johansson PA, Kakavand H, Kefford RF, Lau LMS, Long GV, Pickett HA, Pritchard AL, Pupo GM, Saw RPM, Schramm SJ, Shang CA, Shang P, Spillane AJ, Stretch JR, Tembe V, Thompson JF, Vilain RE, Wilmott JS, Yang JY, Hayward NK, Mann GJ, Scolyer RA, Bartlett J, Bavi P, Chadwick DE, Chan-Seng-Yue M, Cleary S, Connor AA, Czajka K, Denroche RE, Dhani NC, Eagles J, Gallinger S, Grant RC, Hedley D, Hollingsworth MA, Jang GH, Johns J, Kalimuthu S, Liang SB, Lungu I, Luo X, Mbabaali F, McPherson TA, Miller JK, Moore MJ, Notta F, Pasternack D, Petersen GM, Roehrl MHA, Sam M, Selander I, Serra S, Shahabi S, Thayer SP, Timms LE, Wilson GW, Wilson JM, Wouters BG, McPherson JD, Beck TA, Bhandari V, Collins CC, Fleshner NE, Fox NS, Fraser M, Heisler LE, Lalonde E, Livingstone J, Meng A, Sabelnykova VY, Shiah YJ, Van der Kwast T, Bristow RG, Ding S, Fan D, Li L, Nie Y, Xiao X, Xing R, Yang S, Yu Y, Zhou Y, Banks RE, Bourque G, Brennan P, Letourneau L, Riazalhosseini Y, Scelo G, Vasudev N, Viksna J, Lathrop M, Tost J, Ahn SM, Aparicio S, Arnould L, Aure MR, Bhosle SG, Birney E, Borg A, Boyault S, Brinkman AB, Brock JE, Broeks A, Børresen-Dale AL, Caldas C, Chin SF, Davies H, Desmedt C, Dirix L, Dronov S, Ehinger A, Eyfjord JE, Fatima A, Foekens JA, Futreal PA, Garred Ø, Giri DD, Glodzik D, Grabau D, Hilmarsdottir H, Hooijer GK, Jacquemier J, Jang SJ, Jonasson JG, Jonkers J, Kim HY, King TA, Knappskog S, Kong G, Krishnamurthy S, Lakhani SR, Langerød A, Larsimont D, Lee HJ, Lee JY, Lee MTM, Lingjærde OC, MacGrogan G, Martens JWM, O'Meara S, Pauporté I, Pinder S, Pivot X, Provenzano E, Purdie CA, Ramakrishna M, Ramakrishnan K, Reis-Filho J, Richardson AL, Ringnér M, Rodriguez JB, Rodríguez-González FG, Romieu G, Salgado R, Sauer T, Shepherd R, Sieuwerts AM, Simpson PT, Smid M, Sotiriou C, Span PN, Stefánsson ÓA, Stenhouse A, Stunnenberg HG, Sweep F, Tan BKT, Thomas G, Thompson AM, Tommasi S, Treilleux I, Tutt A, Ueno NT, Van Laere S, Van den Eynden GG, Vermeulen P, Viari A, Vincent-Salomon A, Wong BH, Yates L, Zou X, van Deurzen CHM, van de Vijver MJ, Van't Veer L, Ammerpohl O, Aukema S, Bergmann AK, Bernhart SH, Borkhardt A, Borst C, Burkhardt B, Claviez A, Goebler ME, Haake A, Haas S, Hansmann M, Hoell JI, Hummel M, Karsch D, Klapper W, Kneba M, Kreuz M, Kube D, Küppers R, Lenze D, Loeffler M, López C, Mantovani-Löffler L, Möller P, Ott G, Radlwimmer B, Richter J, Rohde M, Rosenstiel PC, Rosenwald A, Schilhabel MB, Schreiber S, Stadler PF, Staib P, Stilgenbauer S, Sungalee S, Szczepanowski M, Toprak UH, Trümper LHP, Wagener R, Zenz T, Hovestadt V, von Kalle C, Kool M, Korshunov A, Landgraf P, Lehrach H, Northcott PA, Pfister SM, Reifenberger G, Warnatz HJ, Wolf S, Yaspo ML, Assenov Y, Gerhauser C, Minner S, Schlomm T, Simon R, Sauter G, Sültmann H, Biswas NK, Maitra A, Majumder PP, Sarin R, Barbi S, Bonizzato G, Cantù C, Dei Tos AP, Fassan M, Grimaldi S, Luchini C, Malleo G, Marchegiani G, Milella M, Paiella S, Pea A, Pederzoli P, Ruzzenente A, Salvia R, Sperandio N, Arai Y, Hama N, Hiraoka N, Hosoda F, Nakamura H, Ojima H, Okusaka T, Totoki Y, Urushidate T, Fukayama M, Ishikawa S, Katai H, Katoh H, Komura D, Rokutan H, Saito-Adachi M, Suzuki A, Taniguchi H, Tatsuno K, Ushiku T, Yachida S, Yamamoto S, Aikata H, Arihiro K, Ariizumi SI, Chayama K, Furuta M, Gotoh K, Hayami S, Hirano S, Kawakami Y, Maejima K, Nakamura T, Nakano K, Ohdan H, Sasaki-Oku A, Tanaka H, Ueno M, Yamamoto M, Yamaue H, Choo SP, Cutcutache I, Khuntikeo N, Ong CK, Pairojkul C, Popescu I, Ahn KS, Aymerich M, Lopez-Guillermo A, López-Otín C, Puente XS, Campo E, Amary F, Baumhoer D, Behjati S, Bjerkehagen B, Futreal PA, Myklebost O, Pillay N, Tarpey P, Tirabosco R, Zaikova O, Flanagan AM, Boultwood J, Bowen DT, Cazzola M, Green AR, Hellstrom-Lindberg E, Malcovati L, Nangalia J, Papaemmanuil E, Vyas P, Ang Y, Barr H, Beardsmore D, Eldridge M, Gossage J, Grehan N, Hanna GB, Hayes SJ, Hupp TR, Khoo D, Lagergren J, Lovat LB, MacRae S, O'Donovan M, O'Neill JR, Parsons SL, Preston SR, Puig S, Roques T, Sanders G, Sothi S, Tavaré S, Tucker O, Turkington R, Underwood TJ, Welch I, Fitzgerald RC, Berney DM, De Bono JS, Cahill D, Camacho N, Dennis NM, Dudderidge T, Edwards SE, Fisher C, Foster CS, Ghori M, Gill P, Gnanapragasam VJ, Gundem G, Hamdy FC, Hawkins S, Hazell S, Howat W, Isaacs WB, Karaszi K, Kay JD, Khoo V, Kote-Jarai Z, Kremeyer B, Kumar P, Lambert A, Leongamornlert DA, Livni N, Lu YJ, Luxton HJ, Marsden L, Massie CE, Matthews L, Mayer E, McDermott U, Merson S, Neal DE, Ng A, Nicol D, Ogden C, Rowe EW, Shah NC, Thomas S, Thompson A, Verrill C, Visakorpi T, Warren AY, Whitaker HC, Zhang H, van As N, Eeles RA, Abeshouse A, Agrawal N, Akbani R, Al-Ahmadie H, Albert M, Aldape K, Ally A, Appelbaum EL, Armenia J, Asa S, Auman JT, Balasundaram M, Balu S, Barnholtz-Sloan J, Bathe OF, Baylin SB, Benz C, Berchuck A, Berrios M, Bigner D, Birrer M, Bodenheimer T, Boice L, Bootwalla MS, Bosenberg M, Bowlby R, Boyd J, Broaddus RR, Brock M, Brooks D, Bullman S, Caesar-Johnson SJ, Carey TE, Carlsen R, Cerfolio R, Chandan VS, Chen HW, Cherniack AD, Chien J, Cho J, Chuah E, Cibulskis C, Cope L, Cordes MG, Curley E, Czerniak B, Danilova L, Davis IJ, Defreitas T, Demchok JA, Dhalla N, Dhir R, Doddapaneni H, El-Naggar A, Felau I, Ferguson ML, Finocchiaro G, Fong KM, Frazer S, Friedman W, Fronick CC, Fulton LA, Gabriel SB, Gao J, Gehlenborg N, Gershenwald JE, Ghossein R, Giama NH, Gibbs RA, Gomez C, Govindan R, Hayes DN, Hegde AM, Heiman DI, Heins Z, Hepperla AJ, Holbrook A, Holt RA, Hoyle AP, Hruban RH, Hu J, Huang M, Huntsman D, Huse J, Iacobuzio-Donahue CA, Ittmann M, Jayaseelan JC, Jefferys SR, Jones CD, Jones SJM, Juhl H, Kang KJ, Karlan B, Kasaian K, Kebebew E, Kim HK, Korchina V, Kundra R, Lai PH, Lander E, Le X, Lee D, Levine DA, Lewis L, Ley T, Li HI, Lin P, Linehan WM, Liu FF, Lu Y, Lype L, Ma Y, Maglinte DT, Mardis ER, Marks J, Marra MA, Matthew TJ, Mayo M, McCune K, Meier SR, Meng S, Mieczkowski PA, Mikkelsen T, Miller CA, Mills GB, Moore RA, Morrison C, Mose LE, Moser CD, Mungall AJ, Mungall K, Mutch D, Muzny DM, Myers J, Newton Y, Noble MS, O'Donnell P, O'Neill BP, Ochoa A, Park JW, Parker JS, Pass H, Pastore A, Pennell NA, Perou CM, Petrelli N, Potapova O, Rader JS, Ramalingam S, Rathmell WK, Reuter V, Reynolds SM, Ringel M, Roach J, Roberts LR, Robertson AG, Sadeghi S, Saller C, Sanchez-Vega F, Schadendorf D, Schein JE, Schmidt HK, Schultz N, Seethala R, Senbabaoglu Y, Shelton T, Shi Y, Shih J, Shmulevich I, Shriver C, Signoretti S, Simons JV, Singer S, Sipahimalani P, Skelly TJ, Smith-McCune K, Socci ND, Soloway MG, Sood AK, Tam A, Tan D, Tarnuzzer R, Thiessen N, Thompson RH, Thorne LB, Tsao M, Umbricht C, Van Den Berg DJ, Van Meir EG, Veluvolu U, Voet D, Wang L, Weinberger P, Weisenberger DJ, Wigle D, Wilkerson MD, Wilson RK, Winterhoff B, Wiznerowicz M, Wong T, Wong W, Xi L, Yau C, Zhang H, Zhang H, Zhang J. Pan-cancer analysis of whole genomes. Nature 2020; 578:82-93. PubMed
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