Research Abstract
My research focuses on 1) pancreatic cancer and 2) intestinal regeneration. We are characterizing factors modulating invasiveness and metastatic potential of pancreatic cancers. Tissue arrays containing resected human pancreatic cancers and a corresponding clinical outcomes database are being constructed to evaluate the clinical importance of specific factors that have been identified using in vitro and in vivo model systems. In addition, we are characterizing the mechanisms of action of intestinal epithelium-specific growth factors and the biology of tissue-engineered intestine.