Photo of Andrea K. Ng,  MD, MPH

Andrea K. Ng, MD, MPH

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 732-6310
Fax: (617) 732-7347


ang@lroc.harvard.edu

Andrea K. Ng, MD, MPH

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Professor, Radiation Oncology, Harvard Medical School
  • Attending Physician, Radiation Oncology, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

The area of my clinical research is on treatment outcome of patients diagnosed with Hodgkin's lymphoma and non-Hodgkin's lymphoma. I especially focus on treatment side effects and late effects of cancer therapy, including second malignancies, cardiopulmonary complications and quality of life of long-term survivors of lymphoma.

Publications from Harvard Catalyst Profiles

Powered by Harvard Catalyst
  • Ahmed S, Bossenberger T, Nalichowski A, Bredfeldt JS, Bartlett S, Bertone K, Dominello M, Dziemianowicz M, Komajda M, Makrigiorgos GM, Marcus KJ, Ng A, Thomas M, Burmeister J. A bi-institutional multi-disciplinary failure mode and effects analysis (FMEA) for a Co-60 based total body irradiation technique. Radiat Oncol 2021; 16:224. PubMed
  • Bergom C, Bradley JA, Ng AK, Samson P, Robinson C, Lopez-Mattei J, Mitchell JD. Past, Present, and Future of Radiation-Induced Cardiotoxicity: Refinements in Targeting, Surveillance, and Risk Stratification. JACC CardioOncol 2021; 3:343-359. PubMed
  • Rizwan R, Gauvreau K, Vinograd C, Yamada JM, Mangano C, Ng AK, Alexander ME, Chen MH. Vopeak in Adult Survivors of Hodgkin Lymphoma: Rate of Decline, Sex Differences, and Cardiovascular Events. JACC CardioOncol 2021; 3:263-273. PubMed
  • Lee SF, Evens AM, Ng AK, Luque-Fernandez MA. Socioeconomic inequalities in treatment and relative survival among patients with diffuse large B-cell lymphoma: a Hong Kong population-based study. Sci Rep 2021; 11:17950. PubMed
  • Mulder RL, Hudson MM, Bhatia S, Landier W, Levitt G, Constine LS, Wallace WH, van Leeuwen FE, Ronckers CM, Henderson TO, Moskowitz CS, Friedman DN, Ng AK, Jenkinson HC, Demoor-Goldschmidt C, Skinner R, Kremer LCM, Oeffinger KC. Updated Breast Cancer Surveillance Recommendations for Female Survivors of Childhood, Adolescent, and Young Adult Cancer From the International Guideline Harmonization Group. J Clin Oncol 2020; 38:4194-4207. PubMed
  • Lee SF, Luque-Fernandez MA, Chen YH, Catalano PJ, Chiang CL, Wan EY, Wong IC, Chen MH, Ng AK. Doxorubicin and subsequent risk of cardiovascular diseases among survivors of diffuse large B-cell lymphoma in Hong Kong. Blood Adv 2020; 4:5107-5117. PubMed
  • Binkley MS, Rauf MS, Milgrom SA, Pinnix CC, Tsang R, Dickinson M, Ng AK, Roberts KB, Gao S, Balogh A, Ricardi U, Levis M, Casulo C, Stolten M, Specht L, Plastaras JP, Wright C, Kelsey CR, Brady JL, Mikhaeel NG, Hoppe BS, Terezakis SA, Picardi M, Della Pepa R, Kirova Y, Akhtar S, Maghfoor I, Koenig JL, Jackson C, Song E, Sehgal S, Advani RH, Natkunam Y, Constine LS, Eich HT, Wirth A, Hoppe RT. Stage I-II nodular lymphocyte-predominant Hodgkin lymphoma: a multi-institutional study of adult patients by ILROG. Blood 2020; 135:2365-2374. PubMed
  • Patel CG, Ng AK. Involved-Site Radiation Therapy for Early-Stage NLPHL. Int J Radiat Oncol Biol Phys 2020; 107:21-22. PubMed
  • Wirth A, Mikhaeel NG, Pauline Aleman BM, Pinnix CC, Constine LS, Wilmot JP, Ricardi U, Illidge TM, Eich HT, Hoppe BS, Dabaja B, Ng AK, Kirova Y, Berthelsen AK, Dieckmann K, Yahalom J, Specht L. Involved Site Radiation Therapy in Adult Lymphomas: An Overview of International Lymphoma Radiation Oncology Group Guidelines. Int J Radiat Oncol Biol Phys 2020. PubMed
  • Kim DW, Lee G, Lee H, Mahal AR, Lam MB, Ng AK. Response to hyperfractionated accelerated radiotherapy in chemotherapy-refractory non-Hodgkin lymphoma. Leuk Lymphoma 2020. PubMed
  • Tseng YD, Ng AK. Hematologic Malignancies. Hematol Oncol Clin North Am 2020; 34:127-142. PubMed
  • Dabaja BS, Ng AK, Terezakis SA, Plastaras JP, Yunes M, Wilson LD, Specht L, Yahalom J. Making Every Single Gray Count: Involved Site Radiation Therapy Delineation Guidelines for Hematological Malignancies. Int J Radiat Oncol Biol Phys 2020; 106:279-281. PubMed
  • Binkley MS, Brady JL, Hajj C, Chelius M, Chau K, Balogh A, Levis M, Filippi AR, Jones M, Ahmed S, MacManus M, Wirth A, Oguchi M, Vistisen AK, Andraos TY, Ng AK, Aleman BMP, Choi SH, Kirova YM, Hardy S, Reinartz G, Eich HT, Bratman SV, Constine LS, Suh CO, Dabaja B, El-Galaly TC, Hodgson DC, Ricardi U, Yahalom J, Mikhaeel NG, Hoppe RT. Salvage Treatment and Survival for Relapsed Follicular Lymphoma Following Primary Radiation Therapy: A Collaborative Study on Behalf of ILROG. Int J Radiat Oncol Biol Phys 2019; 104:522-529. PubMed
  • Wallner PE, Kachnic LA, Alektiar KM, Davis BJ, Hardenbergh PH, Ng AK. The American Board of Radiology Initial Certification in Radiation Oncology: Moving Forward Through Collaboration. Int J Radiat Oncol Biol Phys 2019; 104:21-23. PubMed
  • Tseng YD, Ng AK, Wirth A. New tools of the trade: parsing out the role of radiotherapy for early-stage diffuse large B-cell lymphoma. Leuk Lymphoma 2018. PubMed
  • Brady JL, Binkley MS, Hajj C, Chelius M, Chau K, Balogh A, Levis M, Filippi AR, Jones M, Mac Manus M, Wirth A, Oguchi M, Krog Vistisen A, Andraos TY, Ng AK, Aleman BMP, Choi SH, Kirova Y, Hardy S, Reinartz G, Eich HT, Bratman SV, Constine LS, Suh CO, Dabaja B, El-Galaly TC, Hodgson DC, Ricardi U, Yahalom J, Hoppe RT, Mikhaeel NG. Definitive radiotherapy for localized follicular lymphoma staged by F-FDG PET-CT: a collaborative study by ILROG. Blood 2018. PubMed
  • Tsang RW, Campbell BA, Goda JS, Kelsey CR, Kirova YM, Parikh RR, Ng AK, Ricardi U, Suh CO, Mauch PM, Specht L, Yahalom J. Radiation Therapy for Solitary Plasmacytoma and Multiple Myeloma: Guidelines From the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys 2018; 101:794-808. PubMed
  • Pinnix CC, Ng AK, Dabaja BS, Milgrom SA, Gunther JR, Fuller CD, Smith GL, Abou Yehia Z, Qiao W, Wogan CF, Akhtari M, Mawlawi O, Medeiros LJ, Chuang HH, Martin-Doyle W, Armand P, LaCasce AS, Oki Y, Fanale M, Westin J, Neelapu S, Nastoupil L. Positron emission tomography-computed tomography predictors of progression after DA-R-EPOCH for PMBCL. Blood Adv 2018; 2:1334-1343. PubMed
  • Lalani N, Winkfield KM, Soto DE, Yeap BY, Ng AK, Mauch PM, Jimenez RB. Management and outcomes of women diagnosed with primary breast lymphoma: a multi-institution experience. Breast Cancer Res Treat 2018; 169:197-202. PubMed
  • Constine LS, Yahalom J, Ng AK, Hodgson DC, Wirth A, Milgrom SA, Mikhaeel NG, Eich HT, Illidge T, Ricardi U, Dieckmann K, Moskowitz CH, Advani R, Mauch PM, Specht L, Hoppe RT. The Role of Radiation Therapy in Patients With Relapsed or Refractory Hodgkin Lymphoma: Guidelines From the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys 2018; 100:1100-1118. PubMed
  • Ng AK, Yahalom J, Goda JS, Constine LS, Pinnix CC, Kelsey CR, Hoppe B, Oguchi M, Suh CO, Wirth A, Qi S, Davies A, Moskowitz CH, Laskar S, Li Y, Mauch PM, Specht L, Illidge T. Role of Radiation Therapy in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Guidelines from the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys 2018; 100:652-669. PubMed
  • Patel CG, Michaelson E, Chen YH, Silver B, Marcus KJ, Stevenson MA, Mauch PM, Ng AK. Reduced Mortality Risk in the Recent Era in Early-Stage Hodgkin Lymphoma Patients Treated With Radiation Therapy With or Without Chemotherapy. Int J Radiat Oncol Biol Phys 2017. PubMed
  • Kamran SC, Jacene HA, Chen YH, Mauch PM, Ng AK. Clinical outcome of patients with early stage favorable Hodgkin lymphoma treated with ABVD × two cycles followed by FDG-PET/CT restaging and 20 Gy of involved-site radiotherapy. Leuk Lymphoma 2017. PubMed
  • van Leeuwen FE, Ng AK. Late sequelae in Hodgkin lymphoma survivors. Hematol Oncol 2017; 35 Suppl 1:60-66. PubMed
  • Hodgson D, van Leeuwen F, Ng A, Morton L, Henderson TO. Breast Cancer After Childhood, Adolescent, and Young Adult Cancer: It's Not Just About Chest Radiation. Am Soc Clin Oncol Educ Book 2017; 37:736-745. PubMed
  • van Leeuwen FE, Ng AK. Long-term risk of second malignancy and cardiovascular disease after Hodgkin lymphoma treatment. Hematology Am Soc Hematol Educ Program 2016; 2016:323-330. PubMed
  • Shields H, Li J, Pelletier S, Wang H, Freedman R, Mamon H, Ng A, Freedman A, Come S, Avigan D, Huberman M, Recht A. Persistence of dysphagia and odynophagia after mediastinal radiation and chemotherapy in patients with lung cancer or lymphoma. 2016. PubMed
  • Ng AK, Dabaja BS, Hoppe RT, Illidge T, Yahalom J. Re-Examining the Role of Radiation Therapy for Diffuse Large B-Cell Lymphoma in the Modern Era. J Clin Oncol 2016; 34:1443-7. PubMed
  • Maraldo MV, Ng AK. Minimizing Cardiac Risks With Contemporary Radiation Therapy for Hodgkin Lymphoma. J Clin Oncol 2015. PubMed
  • Nambudiri VE, Vivero M, Watson AJ, Thakuria M, Ng A, Russell S, Rabinowits G, LeBoeuf NR. Merkel Cell Carcinoma Presenting as Subcutaneous Breast Masses: An Uncommon Presentation of a Rare Neuroendocrine Neoplasm. Breast J 2015. PubMed
  • Chandra RA, Wilhite TJ, Balboni TA, Alexander BM, Spektor A, Ott PA, Ng AK, Hodi FS, Schoenfeld JD. A systematic evaluation of abscopal responses following radiotherapy in patients with metastatic melanoma treated with ipilimumab. Oncoimmunology 2015; 4:e1046028. PubMed
  • Tseng YD, Chen YH, Catalano PJ, Ng A. Rates and durability of response to salvage radiation therapy among patients with refractory or relapsed aggressive non-Hodgkin lymphoma. Int J Radiat Oncol Biol Phys 2015; 91:223-31. PubMed
  • Ng AK. Current survivorship recommendations for patients with Hodgkin lymphoma: focus on late effects. Hematology Am Soc Hematol Educ Program 2014; 2014:488-94. PubMed
  • Chen MH, Blackington LH, Zhou J, Chu TF, Gauvreau K, Marcus KJ, Fisher DC, Diller LR, Ng AK. Blood pressure is associated with occult cardiovascular disease in prospectively studied Hodgkin lymphoma survivors after chest radiation. Leuk Lymphoma 2014. PubMed
  • Wattson DA, Hunink MG, DiPiro PJ, Das P, Hodgson DC, Mauch PM, Ng AK. Low-dose chest computed tomography for lung cancer screening among Hodgkin lymphoma survivors: a cost-effectiveness analysis. Int J Radiat Oncol Biol Phys 2014; 90:344-53. PubMed
  • Tieu MT, Cigsar C, Ahmed S, Ng A, Diller L, Millar BA, Crystal P, Hodgson DC. Breast cancer detection among young survivors of pediatric Hodgkin lymphoma with screening magnetic resonance imaging. Cancer 2014. PubMed
  • Michaelson EM, Chen YH, Silver B, Tishler RB, Marcus KJ, Stevenson MA, Ng AK. Thyroid malignancies in survivors of Hodgkin lymphoma. Int J Radiat Oncol Biol Phys 2014; 88:636-41. PubMed
  • Travis LB, Ng AK, Allan JM, Pui CH, Kennedy AR, Xu XG, Purdy JA, Applegate K, Yahalom J, Constine LS, Gilbert ES, Boice JD. Second malignant neoplasms and cardiovascular disease following radiotherapy. Health Phys 2014; 106:229-46. PubMed
  • Beard CJ, Travis LB, Chen MH, Arvold ND, Nguyen PL, Martin NE, Kuban DA, Ng AK, Hoffman KE. Outcomes in stage I testicular seminoma: a population-based study of 9193 patients. Cancer 2013. PubMed
  • Ng AK, Garber JE, Diller LR, Birdwell RL, Feng Y, Neuberg DS, Silver B, Fisher DC, Marcus KJ, Mauch PM. Prospective study of the efficacy of breast magnetic resonance imaging and mammographic screening in survivors of Hodgkin lymphoma. J Clin Oncol 2013. PubMed
  • Russo AL, Chen YH, Martin NE, Vinjamoori A, Luthy SK, Freedman A, Michaelson EM, Silver B, Mauch PM, Ng AK. Low-dose involved-field radiation in the treatment of non-hodgkin lymphoma: predictors of response and treatment failure. Int J Radiat Oncol Biol Phys 2013; 86:121-7. PubMed
  • Travis LB, Demark Wahnefried W, Allan JM, Wood ME, Ng AK. Aetiology, genetics and prevention of secondary neoplasms in adult cancer survivors. Nat Rev Clin Oncol 2013; 10:289-301. PubMed
  • Pashtan I, Mauch PM, Chen YH, Dorfman DM, Silver B, Ng AK. Radiotherapy in the management of localized primary cutaneous B-cell lymphoma. Leuk Lymphoma 2013. PubMed
  • Halasz LM, Jacene HA, Catalano PJ, Van den Abbeele AD, Lacasce A, Mauch PM, Ng AK. Combined modality treatment for PET-positive non-Hodgkin lymphoma: favorable outcomes of combined modality treatment for patients with non-Hodgkin lymphoma and positive interim or postchemotherapy FDG-PET. Int J Radiat Oncol Biol Phys 2012; 83:e647-54. PubMed
  • Vleugels FR, Girouard SD, Schmults CD, Ng AK, Russell SE, Wang LC, Buzney EA. Metastatic eccrine porocarcinoma after Mohs micrographic surgery: a case report. J Clin Oncol 2012; 30:e188-91. PubMed
  • Recklitis CJ, Sanchez Varela V, Ng A, Mauch P, Bober S. Sexual functioning in long-term survivors of Hodgkin's lymphoma. 2010; 19:1229-33. PubMed
  • Galper SL, Yu JB, Mauch PM, Strasser JF, Silver B, Lacasce A, Marcus KJ, Stevenson MA, Chen MH, Ng AK. Clinically significant cardiac disease in patients with Hodgkin lymphoma treated with mediastinal irradiation. Blood 2010. PubMed
  • Cotter SE, Devlin PM, Sahni D, Hansen JL, O'Farrell DA, Ng AK, Wang LC. Treatment of cutaneous metastases of Merkel cell carcinoma with surface-mold computer-optimized high-dose-rate brachytherapy. J Clin Oncol 2010; 28:e464-6. PubMed
  • Ng AK, Abramson JS, Digumarthy SR, Reingold JS, Stone JR. Case records of the Massachusetts General Hospital. Case 24-2010. A 56-year-old woman with a history of Hodgkin's lymphoma and sudden onset of dyspnea and shock. N Engl J Med 2010; 363:664-75. PubMed
  • Hoffman KE, Nguyen PL, Ng AK, D'Amico AV. Prostate Cancer Screening in Men 75 Years Old or Older: An Assessment of Self-Reported Health Status and Life Expectancy. J Urol 2010; 183:1798-802. PubMed
  • Zumsteg ZS, Ng AK. Mucosa-associated lymphoid tissue lymphoma of the breast: bilateral metachronous presentation. Leuk Lymphoma 2010; 51:168-70. PubMed
  • Ng AK, Kenney LB, Gilbert ES, Travis LB. Secondary malignancies across the age spectrum. Semin Radiat Oncol 2010; 20:67-78. PubMed
  • Chen RC, Chin MS, Ng AK, Feng Y, Neuberg D, Silver B, Pinkus GS, Stevenson MA, Mauch PM. Early-stage, lymphocyte-predominant Hodgkin's lymphoma: patient outcomes from a large, single-institution series with long follow-up. J Clin Oncol 2010; 28:136-41. PubMed
  • Rodrigues NA,Killion L,Hickey G,Silver B,Martin C,Stevenson MA,Mauch PM,Ng AK. A Prospective Study of Salivary Gland Function in Lymphoma Patients Receiving Head and Neck Irradiation. Int J Radiat Oncol Biol Phys 2009; 75:1079-83. PubMed
  • Chen AB, Punglia RS, Kuntz KM, Mauch PM, Ng AK. Cost effectiveness and screening interval of lipid screening in Hodgkin's lymphoma survivors. J Clin Oncol 2009; 27:5383-9. PubMed
  • Martin NE, Ng AK. Good things come in small packages: low-dose radiation as palliation for indolent non-Hodgkin lymphomas. Leuk Lymphoma 2009; 50:1765-72. PubMed
  • Ng AK, Travis LB. Radiation therapy and breast cancer risk. J Natl Compr Canc Netw 2009; 7:1121-8. PubMed
  • Sher DJ, Mauch PM, Van Den Abbeele A, Lacasce AS, Czerminski J, Ng AK. Prognostic significance of mid- and post-ABVD PET imaging in Hodgkin's lymphoma: the importance of involved-field radiotherapy. Ann Oncol 2009; 20:1848-53. PubMed
  • Hoffman KE, McCarthy EP, Recklitis CJ, Ng AK. Psychological distress in long-term survivors of adult-onset cancer: results from a national survey. Arch Intern Med 2009; 169:1274-81. PubMed
  • Ng AK,Mauch PM. Late effects of Hodgkin's disease and its treatment. Cancer J 2009; 15:164-8. PubMed
  • Luthy SK,Ng AK,Silver B,Degnan KO,Fisher DC,Freedman AS,Mauch PM. Response to low-dose involved-field radiotherapy in patients with non-Hodgkin's lymphoma. Ann Oncol 2008; 19:2043-7. PubMed
  • Ng AK,Travis LB. Subsequent malignant neoplasms in cancer survivors. Cancer J 2008; 14:429-34. PubMed
  • Ng AK, Li S, Neuberg D, Chi R, Fisher DC, Silver B, Mauch PM. A prospective study of pulmonary function in Hodgkin's lymphoma patients. Ann Oncol 2008; 19:1754-8. PubMed
  • Ng AK, Li S, Recklitis C, Diller LR, Neuberg D, Silver B, Mauch PM. Health Practice in Long-Term Survivors of Hodgkin Lymphoma. Int J Radiat Oncol Biol Phys 2008; 71:468-76. PubMed
  • Ng AK, Travis LB. Second primary cancers: an overview. Hematol Oncol Clin North Am 2008; 22:271-89. PubMed
  • Carver JR, Ng A, Meadows AT, Vaughn DJ. Cardiovascular late effects and the ongoing care of adult cancer survivors. Dis Manag 2008; 11:1-6. PubMed
  • Plumer A, Duan H, Subramaniam S, Lucas FL, Miesfeldt S, Ng AK, Liaw L. Development of fragment-specific osteopontin antibodies and ELISA for quantification in human metastatic breast cancer. BMC Cancer 2008; 8:38. PubMed
  • Lin SJ, Chang C, Ng AK, Wang SH, Li JJ, Hu CP. Prevention of TGF-beta-induced apoptosis by interlukin-4 through Akt activation and p70S6K survival signaling pathways. Apoptosis 2007; 12:1659-70. PubMed
  • Carver JR, Shapiro CL, Ng A, Jacobs L, Schwartz C, Virgo KS, Hagerty KL, Somerfield MR, Vaughn DJ. American Society of Clinical Oncology clinical evidence review on the ongoing care of adult cancer survivors: cardiac and pulmonary late effects. J Clin Oncol 2007; 25:3991-4008. PubMed
  • Ng AK. Diffuse large B-cell lymphoma. Semin Radiat Oncol 2007; 17:169-75. PubMed
  • Tsai HK, Li S, Ng AK, Silver B, Stevenson MA, Mauch PM. Role of radiation therapy in the treatment of stage I/II mucosa-associated lymphoid tissue lymphoma. Ann Oncol 2007; 18:672-8. PubMed
  • Ng AK, Mauch PM. Role of radiation therapy in localized aggressive lymphoma. J Clin Oncol 2007; 25:757-9. PubMed
  • Ng AK, Mauch PM. The impact of treatment on the risk of second malignancy after Hodgkin's disease. Ann Oncol 2006; 17:1727-9. PubMed
  • Ng AK, Li S, Neuberg D, Fisher DC, McMillan C, Silver B, Marcus KC, Stevenson MA, Mauch PM. Long-term results of a prospective trial of mantle irradiation alone for early-stage Hodgkin's disease. Ann Oncol 2006; 17:1693-7. PubMed
  • Guadagnolo BA, Punglia RS, Kuntz KM, Mauch PM, Ng AK. Cost-effectiveness analysis of computerized tomography in the routine follow-up of patients after primary treatment for Hodgkin's disease. J Clin Oncol 2006; 24:4116-22. PubMed
  • Ng A, Constine LS, Advani R, Das P, Flowers C, Friedberg J, Hodgson DC, Schwartz CL, Wilder RB, Wilson LD, Yunes MJ. ACR Appropriateness Criteria: follow-up of Hodgkin's lymphoma. Curr Probl Cancer ; 34:211-27. PubMed
Hide