Photo of Mizuki Nishino, MD, MPH

Mizuki Nishino, MD, MPH

Dana-Farber Cancer Institute

Dana-Farber Cancer Institute

Photo of Mizuki Nishino, MD, MPH

Dana-Farber Cancer Institute

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Mizuki Nishino, MD, MPH

Dana-Farber Cancer Institute

EDUCATIONAL TITLES

  • Professor, Radiology, Harvard Medical School
  • Staff Radiologist, Radiology, Dana-Farber Cancer Institute
  • Staff Radiologist, Radiology, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

I am a Professor of Radiology at Harvard Medical School and a staff radiologist at the Department of Radiology at Brigham and Women's Hospital and Dana-Farber Cancer Institute. I have been engaged in imaging research for lung cancer precision therapy and immunotherapy, supported by R01 and U01 awards from NIH. I am committed to continuing these efforts and make further contributions to move the field of cancer imaging forward.

Publications from Harvard Catalyst Profiles

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  • Nishino M, Hatabu H, Ricciuti B, Vaz V, Michael K, Awad MM. Axillary Lymphadenopathy After Coronavirus Disease 2019 Vaccinations in Patients With Thoracic Malignancy: Incidence, Predisposing Factors, and Imaging Characteristics. J Thorac Oncol 2021. PubMed
  • Nishino M, Lu J, Hino T, Vokes NI, Jänne PA, Hatabu H, Johnson BE. Prediction Model for Tumor Volume Nadir in EGFR-mutant NSCLC Patients Treated With EGFR Tyrosine Kinase Inhibitors. J Thorac Imaging 2021. PubMed
  • Alessi JV, Ricciuti B, Spurr LF, Gupta H, Li YY, Glass C, Nishino M, Cherniack AD, Lindsay J, Sharma B, Felt KD, Rodig SJ, Cheng ML, Sholl LM, Awad MM. SMARCA4 and other SWI/SNF family genomic alterations in non-small cell lung cancer: Clinicopathological characteristics and outcomes to immune checkpoint inhibition. J Thorac Oncol 2021. PubMed
  • Ricciuti B, Jones G, Severgnini M, Alessi JV, Recondo G, Lawrence M, Forshew T, Lydon C, Nishino M, Cheng M, Awad M. Early plasma circulating tumor DNA (ctDNA) changes predict response to first-line pembrolizumab-based therapy in non-small cell lung cancer (NSCLC). J Immunother Cancer 2021. PubMed
  • Johkoh T, Lee KS, Nishino M, Travis WD, Ryu JH, Lee HY, Ryerson CJ, Franquet T, Bankier AA, Brown KK, Goo JM, Kauczor HU, Lynch DA, Nicholson AG, Richeldi L, Schaefer-Prokop CM, Verschakelen J, Raoof S, Rubin GD, Powell C, Inoue Y, Hatabu H. Chest CT Diagnosis and Clinical Management of Drug-related Pneumonitis in Patients Receiving Molecular Targeting Agents and Immune Checkpoint Inhibitors: A Position Paper from the Fleischner Society. Radiology 2021; 298:550-566. PubMed
  • Nishino M. Imaging of Oncologic Treatment-Related Pneumonitis: A Focused Review on Emerging Issues of Immune-Checkpoint Inhibitor Pneumonitis, From the Special Series on Inflammation. AJR Am J Roentgenol 2021. PubMed
  • Alden SL, Swanson SJ, Nishino M, Sholl LM, Awad MM. -Mutant Pulmonary Langerhans Cell Histiocytosis Mimicking Recurrence of Early-Stage -Mutant Lung Adenocarcinoma. JTO Clin Res Rep 2021; 2:100127. PubMed
  • Hida T, Hata A, Lu J, Valtchinov VI, Hino T, Nishino M, Honda H, Tomiyama N, Christiani DC, Hatabu H. Interstitial lung abnormalities in patients with stage I non-small cell lung cancer are associated with shorter overall survival: the Boston lung cancer study. Cancer Imaging 2021; 21:14. PubMed
  • Johkoh T, Lee KS, Nishino M, Travis WD, Ryu JH, Lee HY, Ryerson CJ, Franquet T, Bankier AA, Brown KK, Goo JM, Kauczor HU, Lynch DA, Nicholson AG, Richeldi L, Schaefer-Prokop CM, Verschakelen J, Raoof S, Rubin GD, Powell C, Inoue Y, Hatabu H. Chest CT Diagnosis and Clinical Management of Drug-related Pneumonitis in Patients Receiving Molecular Targeting Agents and Immune Checkpoint Inhibitors: A Position Paper From the Fleischner Society. Chest 2021. PubMed
  • Nishino M, Hong F, Ricciuti B, Hatabu H, Awad MM. Tumor Response Dynamics During First-Line Pembrolizumab Therapy in Patients With Advanced Non-Small-Cell Lung Cancer. JCO Precis Oncol 2021. PubMed
  • Araujo-Filho JAB, Halpenny D, McQuade C, Puthoff G, Chiles C, Nishino M, Ginsberg MS. Management of Pulmonary Nodules in Oncologic Patients: Expert Panel Narrative Review. AJR Am J Roentgenol 2020. PubMed
  • Park HJ, Kim KW, Pyo J, Suh CH, Yoon S, Hatabu H, Nishino M. Incidence of Pseudoprogression during Immune Checkpoint Inhibitor Therapy for Solid Tumors: A Systematic Review and Meta-Analysis. Radiology 2020; 297:87-96. PubMed
  • Park H, Hatabu H, Ricciuti B, Aijazi SJ, Awad MM, Nishino M. Immune-related adverse events on body CT in patients with small-cell lung cancer treated with immune-checkpoint inhibitors. Eur J Radiol 2020; 132:109275. PubMed
  • Mahmood U, Bang A, Chen YH, Mak RH, Lorch JH, Hanna GJ, Nishino M, Manuszak C, Thrash EM, Severgnini M, Sanborn M, Sridharan V, Margalit DN, Tishler RB, Busse PM, Willers H, Mamon HJ, Yoo HJ, Pai SI, Wirth LJ, Haddad RI, Chau NG, Schoenfeld JD. A Randomized Phase 2 Study of Pembrolizumab With or Without Radiation in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma. Int J Radiat Oncol Biol Phys 2020. PubMed
  • Alessi JV, Ricciuti B, Jiménez-Aguilar E, Hong F, Wei Z, Nishino M, Plodkowski AJ, Sawan P, Luo J, Rizvi H, Carter BW, Heymach JV, Altan M, Hellmann M, Awad M. Outcomes to first-line pembrolizumab in patients with PD-L1-high (≥50%) non-small cell lung cancer and a poor performance status. J Immunother Cancer 2020. PubMed
  • Axelsson GT, Putman RK, Aspelund T, Gudmundsson EF, Hida T, Araki T, Nishino M, Hatabu H, Gudnason V, Hunninghake GM, Gudmundsson G. The Associations of Interstitial Lung Abnormalities with Cancer Diagnoses and Mortality. Eur. Respir. J. 2020. PubMed
  • Thomas R, Chen YH, Hatabu H, Mak RH, Nishino M. Radiographic patterns of symptomatic radiation pneumonitis in lung cancer patients: Imaging predictors for clinical severity and outcome. Lung Cancer 2020; 145:132-139. PubMed
  • Ricciuti B, Recondo G, Spurr LF, Li YY, Lamberti G, Venkatraman D, Umeton R, Cherniack AD, Nishino M, Sholl LM, Shapiro GI, Awad MM, Cheng ML. Impact of DNA Damage Response and Repair (DDR) Gene Mutations on Efficacy of PD-(L)1 Immune Checkpoint Inhibition in Non-Small Cell Lung Cancer. Clin Cancer Res 2020. PubMed
  • Naidoo J, Nishino M, Patel SP, Shankar B, Rekhtman N, Illei P, Camus P. Immune-Related Pneumonitis After Chemoradiotherapy and Subsequent Immune Checkpoint Blockade in Unresectable Stage III Non-Small-Cell Lung Cancer. Clin Lung Cancer 2020. PubMed
  • Recondo G, Bahcall M, Spurr LF, Che J, Ricciuti B, Leonardi GC, Lo YC, Li YY, Lamberti G, Nguyen T, Milan MSD, Venkatraman D, Umeton R, Paweletz CP, Albayrak A, Cherniack AD, Price KS, Fairclough SR, Nishino M, Sholl LM, Oxnard GR, Janne PA, Awad MM. Molecular mechanisms of acquired resistance to MET tyrosine kinase inhibitors in patients with MET exon 14 mutant NSCLC. Clin Cancer Res 2020. PubMed
  • Nishino M, Hida T, Kravets S, Dahlberg SE, Lydon CA, Hatabu H, Johnson BE, Awad MM. Tumor volume dynamics and tumor growth rate in -rearranged advanced non-small-cell lung cancer treated with crizotinib. European J Radiol Open 2020; 7:100210. PubMed
  • Naidoo J, Reuss JE, Suresh K, Feller-Kopman D, Forde PM, Mehta Steinke S, Rock C, Johnson DB, Nishino M, Brahmer JR. Immune-related (IR)-pneumonitis during the COVID-19 pandemic: multidisciplinary recommendations for diagnosis and management. J Immunother Cancer 2020. PubMed
  • Park H, Sholl LM, Hatabu H, Awad MM, Nishino M. Imaging of Precision Therapy for Lung Cancer: Current State of the Art. Radiology 2019; 293:15-29. PubMed
  • Sears CR, Peikert T, Possick JD, Naidoo J, Nishino M, Patel SP, Camus P, Gaga M, Garon EB, Gould MK, Limper AH, Montgrain PR, Travis WD, Rivera MP. Knowledge Gaps and Research Priorities in Immune Checkpoint Inhibitor-related Pneumonitis. An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med 2019; 200:e31-e43. PubMed
  • Ricciuti B, Dahlberg SE, Adeni A, Sholl LM, Nishino M, Awad MM. Immune Checkpoint Inhibitor Outcomes for Patients With Non-Small-Cell Lung Cancer Receiving Baseline Corticosteroids for Palliative Versus Nonpalliative Indications. J Clin Oncol 2019. PubMed
  • Suh CH, Kim KW, Pyo J, Hatabu H, Nishino M. The incidence of ALK inhibitor-related pneumonitis in advanced non-small-cell lung cancer patients: A systematic review and meta-analysis. Lung Cancer 2019; 132:79-86. PubMed
  • Schoenfeld JD, Nishino M, Severgnini M, Manos M, Mak RH, Hodi FS. Pneumonitis resulting from radiation and immune checkpoint blockade illustrates characteristic clinical, radiologic and circulating biomarker features. J Immunother Cancer 2019; 7:112. PubMed
  • Hida T, Dahlberg SE, Lydon CA, Hatabu H, Johnson BE, Awad MM, Nishino M. Tumor Volume Analysis as a Predictive Marker for Prolonged Survival in Anaplastic Lymphoma Kinase-rearranged Advanced Non-Small Cell Lung Cancer Patients Treated With Crizotinib. J Thorac Imaging 2019. PubMed
  • Ricciuti B, Kravets S, Dahlberg SE, Umeton R, Albayrak A, Subegdjo SJ, Johnson BE, Nishino M, Sholl LM, Awad MM. Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer. J Immunother Cancer 2019; 7:87. PubMed
  • Lee G, Bak SH, Lee HY, Choi JY, Park H, Lee SH, Ohno Y, Nishino M, van Beek EJR, Lee KS. Measurement Variability in Treatment Response Determination for Non-Small Cell Lung Cancer: Improvements Using Radiomics. J Thorac Imaging 2019; 34:103-115. PubMed
  • Alessandrino F, Sahu S, Nishino M, Adeni AE, Tirumani SH, Shinagare AB, Awad MM. Frequency and imaging features of abdominal immune-related adverse events in metastatic lung cancer patients treated with PD-1 inhibitor. Abdom Radiol (NY) 2019. PubMed
  • Park H, Dahlberg SE, Lydon CA, Araki T, Hatabu H, Rabin MS, Johnson BE, Nishino M. M1b Disease in the 8th Edition of TNM Staging of Lung Cancer: Pattern of Single Extrathoracic Metastasis and Clinical Outcome. Oncologist 2019. PubMed
  • Hung YP, Hunninghake GM, Miller ER, Putman R, Nishino M, Araki T, Hatabu H, Sholl LM, Vivero M. Incidental non-neoplastic parenchymal findings in patients undergoing lung resection for mass lesions. Hum Pathol 2019. PubMed
  • Araki T, Dahlberg SE, Hida T, Lydon CA, Rabin MS, Hatabu H, Johnson BE, Nishino M. Interstitial lung abnormality in stage IV non-small cell lung cancer: A validation study for the association with poor clinical outcome. European J Radiol Open 2019; 6:128-131. PubMed
  • Vokes NI, Liu D, Ricciuti B, Jimenez-Aguilar E, Rizvi H, Dietlein F, He MX, Margolis CA, Elmarakeby HA, Girshman J, Adeni A, Sanchez-Vega F, Schultz N, Dahlberg S, Zehir A, Jänne PA, Nishino M, Umeton R, Sholl LM, Van Allen EM, Hellmann MD, Awad MM. Harmonization of Tumor Mutational Burden Quantification and Association With Response to Immune Checkpoint Blockade in Non-Small-Cell Lung Cancer. JCO Precis Oncol 2019. PubMed
  • Nishino M, Hatabu H, Hodi FS. Imaging of Cancer Immunotherapy: Current Approaches and Future Directions. Radiology 2019; 290:9-22. PubMed
  • Nishino M. Perinodular Radiomic Features to Assess Nodule Microenvironment: Does It Help to Distinguish Malignant versus Benign Lung Nodules? Radiology 2018. PubMed
  • Nishino M, Wakai S, Hida T, Dahlberg SE, Ozaki M, Hatabu H, Tachizaki H, Johnson BE. Automated image analysis tool for tumor volume growth rate to guide precision cancer therapy: EGFR-mutant non-small-cell lung cancer as a paradigm. Eur J Radiol 2018; 109:68-76. PubMed
  • Park H, Nishino M, Hornick JL, Jacobsen ED. Imaging of Histiocytosis in the Era of Genomic Medicine. Radiographics 2018. PubMed
  • Suh CH, Park HS, Kim KW, Pyo J, Hatabu H, Nishino M. Pneumonitis in advanced non-small-cell lung cancer patients treated with EGFR tyrosine kinase inhibitor: Meta-analysis of 153 cohorts with 15,713 patients: Meta-analysis of incidence and risk factors of EGFR-TKI pneumonitis in NSCLC. Lung Cancer 2018; 123:60-69. PubMed
  • Bahcall M, Awad MM, Sholl LM, Wilson FH, Xu M, Wang S, Palakurthi S, Choi J, Ivanova EV, Leonardi GC, Ulrich BC, Paweletz CP, Kirschmeier PT, Watanabe M, Baba H, Nishino M, Nagy RJ, Lanman RB, Capelletti M, Chambers ES, Redig AJ, VanderLaan PA, Costa DB, Imamura Y, Jänne PA. Amplification of Wild-type Imparts Resistance to Crizotinib in Exon 14 Mutant Non-Small Cell Lung Cancer. Clin Cancer Res 2018. PubMed
  • Skoulidis F, Goldberg ME, Greenawalt DM, Hellmann MD, Awad MM, Gainor JF, Schrock AB, Hartmaier RJ, Trabucco SE, Gay L, Ali SM, Elvin JA, Singal G, Ross JS, Fabrizio D, Szabo PM, Chang H, Sasson A, Srinivasan S, Kirov S, Szustakowski J, Vitazka P, Edwards R, Bufill JA, Sharma N, Ou SI, Peled N, Spigel DR, Rizvi H, Aguilar EJ, Carter BW, Erasmus J, Halpenny DF, Plodkowski AJ, Long NM, Nishino M, Denning WL, Galan-Cobo A, Hamdi H, Hirz T, Tong P, Wang J, Rodriguez-Canales J, Villalobos PA, Parra ER, Kalhor N, Sholl LM, Sauter JL, Jungbluth AA, Mino-Kenudson M, Azimi R, Elamin YY, Zhang J, Leonardi GC, Jiang F, Wong KK, Lee JJ, Papadimitrakopoulou VA, Wistuba II, Miller VA, Frampton GM, Wolchok JD, Shaw AT, Jänne PA, Stephens PJ, Rudin CM, Geese WJ, Albacker LA, Heymach JV. Mutations and PD-1 Inhibitor Resistance in -Mutant Lung Adenocarcinoma. 2018; 8:822-835. PubMed
  • Nishino M, Sholl LM, Awad MM, Hatabu H, Armand P, Hodi FS. Sarcoid-Like Granulomatosis of the Lung Related to Immune-Checkpoint Inhibitors: Distinct Clinical and Imaging Features of a Unique Immune-Related Adverse Event. Cancer Immunol Res 2018; 6:630-635. PubMed
  • Nishino M. Tumor Response Assessment for Precision Cancer Therapy: Response Evaluation Criteria in Solid Tumors and Beyond. Am Soc Clin Oncol Educ Book 2018. PubMed
  • Abravanel DL, Nishino M, Sholl LM, Ambrogio C, Awad MM. An Acquired NRAS Q61K Mutation in BRAF V600E-Mutant Lung Adenocarcinoma Resistant to Dabrafenib Plus Trametinib. J Thorac Oncol 2018. PubMed
  • Hodi FS, Ballinger M, Lyons B, Soria JC, Nishino M, Tabernero J, Powles T, Smith D, Hoos A, McKenna C, Beyer U, Rhee I, Fine G, Winslow N, Chen DS, Wolchok JD. Immune-Modified Response Evaluation Criteria In Solid Tumors (imRECIST): Refining Guidelines to Assess the Clinical Benefit of Cancer Immunotherapy. J Clin Oncol 2018; 36:850-858. PubMed
  • Miller ER, Putman RK, Vivero M, Hung Y, Araki T, Nishino M, Washko GR, Rosas IO, Hatabu H, Sholl LM, Hunninghake GM. Histopathology of Interstitial Lung Abnormalities in the Context of Lung Nodule Resections. Am J Respir Crit Care Med 2017. PubMed
  • Nishino M, Giobbie-Hurder A, Manos MP, Bailey N, Buchbinder EI, Ott PA, Ramaiya NH, Hodi FS. Immune-Related Tumor Response Dynamics in Melanoma Patients Treated with Pembrolizumab: Identifying Markers for Clinical Outcome and Treatment Decisions. Clin Cancer Res 2017. PubMed
  • Nishino M, Dahlberg SE, Adeni AE, Lydon C, Hatabu H, Janne PA, Hodi FS, Awad MM. Tumor response dynamics of advanced non-small-cell lung cancer patients treated with PD-1 inhibitors: Imaging markers for treatment outcome. Clin Cancer Res 2017. PubMed
  • Nishino M, Ramaiya NH, Hatabu H, Hodi FS. Monitoring immune-checkpoint blockade: response evaluation and biomarker development. Nat Rev Clin Oncol 2017. PubMed
  • Nishino M, Sacher AG, Gandhi L, Chen Z, Akbay E, Fedorov A, Westin CF, Hatabu H, Johnson BE, Hammerman P, Wong KK. Co-clinical quantitative tumor volume imaging in ALK-rearranged NSCLC treated with crizotinib. Eur J Radiol 2017; 88:15-20. PubMed
  • Comstock DE, Nishino M, Giardino AA. Headache in the Setting of Immunotherapy Treatment for Metastatic Melanoma. JAMA Oncol 2017. PubMed
  • Nishino M, Hatabu H. Programmed Death-1/Programmed Death Ligand-1 Inhibitor-Related Pneumonitis and Radiographic Patterns. J Clin Oncol 2017. PubMed
  • Nishino M, Hatabu H, Hodi FS, Ramaiya NH. Drug-Related Pneumonitis in the Era of Precision Cancer Therapy. JCO Precis Oncol 2017. PubMed
  • Nishino M, Hatabu H. Osimertinib in EGFR T790M-Positive Lung Cancer. N Engl J Med 2017; 376:1992-3. PubMed
  • Nishino M, Ramaiya NH, Awad MM, Sholl LM, Maattala JA, Taibi M, Hatabu H, Ott PA, Armand PF, Hodi FS. PD-1 Inhibitor-Related Pneumonitis in Advanced Cancer Patients: Radiographic Patterns and Clinical Course. Clin Cancer Res 2016. PubMed
  • Nishino M, Ramaiya NH, Hatabu H, Hodi FS, Armand PF. PD-1 inhibitor-related pneumonitis in lymphoma patients treated with single-agent pembrolizumab therapy. British Journal of Haematology 2016. PubMed
  • Nishino M. Pseudoprogression and Measurement Variability. J Clin Oncol 2016; 34:3480-1. PubMed
  • Nishino M, Giobbie-Hurder A, Hatabu H, Ramaiya NH, Hodi FS. Incidence of Programmed Cell Death 1 Inhibitor-Related Pneumonitis in Patients With Advanced Cancer: A Systematic Review and Meta-analysis. JAMA Oncol 2016. PubMed
  • Lampson BL, Nishino M, Dahlberg SE, Paul D, Santos AA, Jänne PA, Oxnard GR. Activity of erlotinib when dosed below the maximum tolerated dose for EGFR-mutant lung cancer: Implications for targeted therapy development. Cancer 2016. PubMed
  • Chong CR, Bahcall M, Capelletti M, Kosaka T, Ercan D, Sim T, Sholl LM, Nishino M, Johnson BE, Gray NS, Janne PA. Identification of existing drugs that effectively target NTRK1- and ROS1-rearrangements in lung cancer. Clin Cancer Res 2016. PubMed
  • Nishino M, Chambers ES, Chong CR, Ramaiya NH, Gray SW, Marcoux JP, Hatabu H, Jänne PA, Hodi FS, Awad MM. Anti-PD-1 Inhibitor-Related Pneumonitis in Non-Small Cell Lung Cancer. Cancer Immunol Res 2016; 4:289-93. PubMed
  • Nishino M, Dahlberg SE, Fulton LE, Digumarthy SR, Hatabu H, Johnson BE, Sequist LV. Volumetric Tumor Response and Progression in EGFR-mutant NSCLC Patients Treated with Erlotinib or Gefitinib. Acad Radiol 2016. PubMed
  • Nishino M, Brais LK, Brooks NV, Hatabu H, Kulke MH, Ramaiya NH. Drug-related pneumonitis during mammalian target of rapamycin inhibitor therapy in patients with neuroendocrine tumors: a radiographic pattern-based approach. Eur J Cancer 2016; 53:163-70. PubMed
  • Tirumani SH, Shinagare AB, O'Neill AC, Nishino M, Rosenthal MH, Ramaiya NH. Accuracy and feasibility of estimated tumour volumetry in primary gastric gastrointestinal stromal tumours: validation using semiautomated technique in 127 patients. Eur Radiol 2016. PubMed
  • Nishino M. Immune-related response evaluations during immune-checkpoint inhibitor therapy: establishing a "common language" for the new arena of cancer treatment. J Immunother Cancer 2016; 4:30. PubMed
  • Nishino M, Ramaiya NH, Chambers ES, Adeni AE, Hatabu H, Jänne PA, Hodi FS, Awad MM. Immune-related response assessment during PD-1 inhibitor therapy in advanced non-small-cell lung cancer patients. J Immunother Cancer 2016; 4:84. PubMed
  • Kubo T, Ohno Y, Takenaka D, Nishino M, Gautam S, Sugimura K, Kauczor HU, Hatabu H, . Standard-dose vs. low-dose CT protocols in the evaluation of localized lung lesions: Capability for lesion characterization-iLEAD study. European J Radiol Open 2016; 3:67-73. PubMed
  • Shinagare AB, O'Neill AC, Cheng S, Somarouthu B, Tirumani SH, Nishino M, Van den Abbeele AD, Ramaiya NH. Advanced High-Grade Serous Ovarian Cancer: Frequency and Timing of Thoracic Metastases and the Implications for Chest Imaging Follow-up. Radiology 2015. PubMed
  • Gao X, Sholl LM, Nishino M, Heng JC, Jänne PA, Oxnard GR. Clinical Implications of Variant ALK FISH Rearrangement Patterns. J Thorac Oncol 2015; 10:1648-52. PubMed
  • Tirumani SH, Ramaiya NH, Keraliya A, Bailey ND, Ott PA, Hodi FS, Nishino M. Radiographic Profiling of Immune-Related Adverse Events in Advanced Melanoma Patients Treated with Ipilimumab. Cancer Immunol Res 2015. PubMed
  • Nishino M, Boswell EN, Hatabu H, Ghobrial IM, Ramaiya NH. Drug-Related Pneumonitis During Mammalian Target of Rapamycin Inhibitor Therapy: Radiographic Pattern-Based Approach in Waldenström Macroglobulinemia as a Paradigm. Oncologist 2015; 20:1077-83. PubMed
  • Luke JJ, Donahue H, Nishino M, Giobbie-Hurder A, Davis M, Bailey N, Ott PA, Hodi FS. Single Institution Experience of Ipilimumab 3 mg/kg with Sargramostim (GM-CSF) in Metastatic Melanoma. Cancer Immunol Res 2015. PubMed
  • Lo PC, Dahlberg SE, Nishino M, Johnson BE, Sequist LV, Jackman DM, Jänne PA, Oxnard GR. Delay of treatment change after objective progression on first-line erlotinib in epidermal growth factor receptor-mutant lung cancer. Cancer 2015. PubMed
  • Nishino M, Sholl LM, Hodi FS, Hatabu H, Ramaiya NH. Anti-PD-1-Related Pneumonitis during Cancer Immunotherapy. N Engl J Med 2015; 373:288-90. PubMed
  • Nishino M, Tirumani SH, Ramaiya NH, Hodi FS. Cancer immunotherapy and immune-related response assessment: The role of radiologists in the new arena of cancer treatment. Eur J Radiol 2015; 84:1259-68. PubMed
  • Sholl LM, Nishino M, Pokharel S, Mino-Kenudson M, French CA, Janne PA, Lathan C. Primary Pulmonary NUT Midline Carcinoma: Clinical, Radiographic, and Pathologic Characterizations. J Thorac Oncol 2015; 10:951-9. PubMed
  • Fairchild A, Tirumani SH, Rosenthal MH, Howard SA, Krajewski KM, Nishino M, Shinagare AB, Jagannathan JP, Ramaiya NH. Hormonal therapy in oncology: a primer for the radiologist. AJR Am J Roentgenol 2015; 204:W620-30. PubMed
  • Nishino M, Cardarella S, Dahlberg SE, Araki T, Lydon C, Jackman DM, Rabin MS, Hatabu H, Johnson BE. Interstitial lung abnormalities in treatment-naïve advanced non-small-cell lung cancer patients are associated with shorter survival. Eur J Radiol 2015. PubMed
  • Krajewski KM, Nishino M, Ramaiya NH, Choueiri TK. RECIST 1.1 compared with RECIST 1.0 in patients with advanced renal cell carcinoma receiving vascular endothelial growth factor-targeted therapy. AJR Am J Roentgenol 2015; 204:W282-8. PubMed
  • Chong CR, Wirth LJ, Nishino M, Chen AB, Sholl LM, Kulke MH, McNamee CJ, Jänne PA, Johnson BE. Chemotherapy for locally advanced and metastatic pulmonary carcinoid tumors. Lung Cancer 2014. PubMed
  • Araki T, Sholl LM, Gerbaudo VH, Hatabu H, Nishino M. Thymic measurements in pathologically proven normal thymus and thymic hyperplasia: intraobserver and interobserver variabilities. Acad Radiol 2014; 21:733-42. PubMed
  • Krajewski KM, Franchetti Y, Nishino M, Fay AP, Ramaiya N, Van den Abbeele AD, Choueiri TK. 10% Tumor diameter shrinkage on the first follow-up computed tomography predicts clinical outcome in patients with advanced renal cell carcinoma treated with angiogenesis inhibitors: a follow-up validation study. Oncologist 2014. PubMed
  • Nishino M, Hatabu H, Johnson BE, McLoud TC. State of the art: Response assessment in lung cancer in the era of genomic medicine. Radiology 2014; 271:6-27. PubMed
  • Araki T, Sholl LM, Gerbaudo VH, Hatabu H, Nishino M. Imaging characteristics of pathologically proven thymic hyperplasia: identifying features that can differentiate true from lymphoid hyperplasia. AJR Am J Roentgenol 2014; 202:471-8. PubMed
  • Krajewski KM, Nishino M, Franchetti Y, Ramaiya NH, Van den Abbeele AD, Choueiri TK. Intraobserver and interobserver variability in computed tomography size and attenuation measurements in patients with renal cell carcinoma receiving antiangiogenic therapy: implications for alternative response criteria. Cancer 2014; 120:711-21. PubMed
  • Nishino M, Itoh H, Hatabu H. A practical approach to high-resolution CT of diffuse lung disease. Eur J Radiol 2014. PubMed
  • Nishino M, Giobbie-Hurder A, Ramaiya NH, Hodi FS. Response assessment in metastatic melanoma treated with ipilimumab and bevacizumab: CT tumor size and density as markers for response and outcome. J Immunother Cancer 2014; 2:40. PubMed
  • Nishino M, Gargano M, Suda M, Ramaiya NH, Hodi FS. Optimizing immune-related tumor response assessment: does reducing the number of lesions impact response assessment in melanoma patients treated with ipilimumab? J Immunother Cancer 2014; 2:17. PubMed
  • Cooley C, Nishino M, Jagannathan J, Ramaiya N, Di Salvo D, Krajewski KM. Clinical problem solving: utility of sonography in oncologic patients. J Ultrasound Med 2014; 33:9-22. PubMed
  • Nishino M, Dahlberg SE, Cardarella S, Jackman DM, Rabin MS, Ramaiya NH, Hatabu H, Jänne PA, Johnson BE. Volumetric tumor growth in advanced non-small cell lung cancer patients with EGFR mutations during EGFR-tyrosine kinase inhibitor therapy: developing criteria to continue therapy beyond RECIST progression. Cancer 2013; 119:3761-8. PubMed
  • Cardarella S, Ogino A, Nishino M, Butaney M, Shen J, Lydon C, Yeap BY, Sholl LM, Johnson BE, Jänne PA. Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer. Clin Cancer Res 2013; 19:4532-40. PubMed
  • Nishino M, Dahlberg SE, Cardarella S, Jackman DM, Rabin MS, Hatabu H, Jänne PA, Johnson BE. Tumor volume decrease at 8 weeks is associated with longer survival in EGFR-mutant advanced non-small-cell lung cancer patients treated with EGFR TKI. J Thorac Oncol 2013; 8:1059-68. PubMed
  • Nishino M, Giobbie-Hurder A, Gargano M, Suda M, Ramaiya NH, Hodi FS. Developing a common language for tumor response to immunotherapy: immune-related response criteria using unidimensional measurements. Clin Cancer Res 2013; 19:3936-43. PubMed
  • Nishino M, Cardarella S, Jackman DM, Ramaiya NH, Rabin MS, Hatabu H, Jänne PA, Johnson BE. RECIST 1.1 in NSCLC patients with EGFR mutations treated with EGFR tyrosine kinase inhibitors: comparison with RECIST 1.0. AJR Am J Roentgenol 2013; 201:W64-71. PubMed
  • Nishino M, Cardarella S, Dahlberg SE, Jackman DM, Ramaiya NH, Hatabu H, Rabin MS, Jänne PA, Johnson BE. Radiographic assessment and therapeutic decisions at RECIST progression in EGFR-mutant NSCLC treated with EGFR tyrosine kinase inhibitors. Lung Cancer 2013; 79:283-8. PubMed
  • Oxnard GR, Lo PC, Nishino M, Dahlberg SE, Lindeman NI, Butaney M, Jackman DM, Johnson BE, Jänne PA. Natural history and molecular characteristics of lung cancers harboring EGFR exon 20 insertions. J Thorac Oncol 2013; 8:179-84. PubMed
  • Kamran SC, Shinagare AB, Howard SA, Nishino M, Hornick JL, Krajewski KM, Ramaiya NH. Intrathoracic malignant peripheral nerve sheath tumors: imaging features and implications for management. Radiol Oncol 2013; 47:230-8. PubMed
  • Shinagare AB, Okajima Y, Oxnard GR, Dipiro PJ, Johnson BE, Hatabu H, Nishino M. Unsuspected pulmonary embolism in lung cancer patients: comparison of clinical characteristics and outcome with suspected pulmonary embolism. Lung Cancer 2012; 78:161-6. PubMed
  • Nishino M, Cryer SK, Okajima Y, Sholl LM, Hatabu H, Rabin MS, Jackman DM, Johnson BE. Tumoral cavitation in patients with non-small-cell lung cancer treated with antiangiogenic therapy using bevacizumab. Cancer Imaging 2012; 12:225-35. PubMed
  • Shinagare AB, Guo M, Hatabu H, Krajewski KM, Andriole K, Van den Abbeele AD, DiPiro PJ, Nishino M. Incidence of pulmonary embolism in oncologic outpatients at a tertiary cancer center. Cancer 2011. PubMed
  • Nishino M, Jackman DM, Hatabu H, Jänne PA, Johnson BE, Van den Abbeele AD. Imaging of lung cancer in the era of molecular medicine. Acad Radiol 2011; 18:424-36. PubMed
  • Washko GR, Hunninghake GM, Fernandez IE, Nishino M, Okajima Y, Yamashiro T, Ross JC, Estépar RS, Lynch DA, Brehm JM, Andriole KP, Diaz AA, Khorasani R, D'Aco K, Sciurba FC, Silverman EK, Hatabu H, Rosas IO, . Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med 2011; 364:897-906. PubMed
  • Nishino M, Guo M, Jackman DM, DiPiro PJ, Yap JT, Ho TK, Hatabu H, Jänne PA, Van den Abbeele AD, Johnson BE. CT tumor volume measurement in advanced non-small-cell lung cancer: Performance characteristics of an emerging clinical tool. Acad Radiol 2011; 18:54-62. PubMed
  • O'Regan KN, Nishino M, Armand P, Kelly PJ, Hwang DG, Di Salvo D. Sonographic features of pectoralis muscle necrosis secondary to gemcitabine-induced radiation recall: case report and review of current literature. J Ultrasound Med 2010; 29:1499-502. PubMed
  • Nishino M, Jackman DM, Hatabu H, Yeap BY, Cioffredi LA, Yap JT, Jänne PA, Johnson BE, Van den Abbeele AD. New Response Evaluation Criteria in Solid Tumors (RECIST) guidelines for advanced non-small cell lung cancer: comparison with original RECIST and impact on assessment of tumor response to targeted therapy. AJR Am J Roentgenol 2010; 195:W221-8. PubMed
  • Nishino M, Jagannathan JP, Ramaiya NH, Van den Abbeele AD. Revised RECIST guideline version 1.1: What oncologists want to know and what radiologists need to know. AJR Am J Roentgenol 2010; 195:281-9. PubMed
  • Nishino M, Patrick JL, Connors JM. Case 155: Lane-Hamilton syndrome. Radiology 2010; 254:985-8. PubMed
  • Nishino M, Washko GR, Hatabu H. Volumetric expiratory HRCT of the lung: clinical applications. Thorac Surg Clin 2010; 20:121-7, viii-ix. PubMed
  • Nishino M, Washko GR, Hatabu H. Volumetric expiratory HRCT of the lung: clinical applications. Radiol Clin North Am 2010; 48:177-83. PubMed
  • Nishino M, Lee KS, Itoh H, Hatabu H. The spectrum of pulmonary sarcoidosis: variations of high-resolution CT findings and clues for specific diagnosis. Eur J Radiol 2010; 73:66-73. PubMed
  • Kido A, Togashi K, Nishino M, Miyake K, Koyama T, Fujimoto R, Iwasaku K, Fujii S, Hayakawa K. Cine MR imaging of uterine peristalsis in patients with endometriosis. Eur Radiol 2007; 17:1813-9. PubMed
  • Nishino M, Kubo T, Kataoka ML, Raptopoulos V, Hatabu H. Coronal reformations of the chest on 64-row multi-detector row CT: evaluation of image quality in comparison with 16-, 8- and 4-row multi-detector row CT. Eur J Radiol 2006; 59:231-7. PubMed
  • Ward VL, Nishino M, Hatabu H, Estroff JA, Barnewolt CE, Feldman HA, Levine D. Fetal lung volume measurements: determination with MR imaging--effect of various factors. Radiology 2006; 240:187-93. PubMed
  • Nishino M, Kubo T, Kataoka ML, Gautam S, Raptopoulos V, Hatabu H. Evaluation of thoracic abnormalities on 64-row multi-detector row CT: comparison between axial images versus coronal reformations. Eur J Radiol 2006; 59:33-41. PubMed
  • Kuroki M, Nishino M, Takahashi M, Mori Y, Raptopoulos VD, Boiselle PM, Tamura S, Hatabu H. Incidence of pulmonary embolism in younger versus older patients using CT. J Thorac Imaging 2006; 21:167-71. PubMed
  • Nishino M, Roberts DH, Sitek A, Raptopoulos V, Boiselle PM, Hatabu H. Loss of anteroposterior intralobar attenuation gradient of the lung: Correlation with pulmonary function. Acad Radiol 2006; 13:589-97. PubMed
  • Nishino M, Hatabu H. Volumetric expiratory HRCT imaging with MSCT. J Thorac Imaging 2005; 20:176-85. PubMed
  • Miyake K, Hayakawa K, Nishino M, Morimoto T, Mukaihara S. Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer. Acad Radiol 2005; 12:722-7. PubMed
  • Boiselle PM, Hasegawa I, Nishino M, Raptopoulos V, Hatabu H. Comparison of artifacts on coronal reformation and axial CT pulmonary angiography images using single-detector and 4- and 8-detector multidetector-row helical CT scanners. Acad Radiol 2005; 12:602-7. PubMed
  • Nishino M, Kuroki M, Roberts DH, Mori Y, Boiselle PM, Hatabu H. Bronchomalacia in sarcoidosis: evaluation on volumetric expiratory high-resolution CT of the lung. Acad Radiol 2005; 12:596-601. PubMed
  • Baroni RH, Feller-Kopman D, Nishino M, Hatabu H, Loring SH, Ernst A, Boiselle PM. Tracheobronchomalacia: comparison between end-expiratory and dynamic expiratory CT for evaluation of central airway collapse. Radiology 2005; 235:635-41. PubMed
  • Nishino M, Iwata S, Hayakawa K, Kanao S, Morimoto T, Mukaihara S, Hatabu H. Functional evaluation of the postoperative gastrointestinal tract using kinematic MR imaging: Quantitative assessment of peristaltic activity. Eur J Radiol 2005; 53:263-7. PubMed
  • Yam CS, Levine D, Nishino M, Sitek A, Larson M. A simple method for displaying cine images on web-based teaching files. AJR Am J Roentgenol 2005; 184:691-4. PubMed
  • Nishino M, Togashi K, Nakai A, Hayakawa K, Kanao S, Iwasaku K, Fujii S. Uterine contractions evaluated on cine MR imaging in patients with uterine leiomyomas. Eur J Radiol 2005; 53:142-6. PubMed
  • Nishino M, Kuroki M, Boiselle PM, Raptopoulos V, Hatabu H. Sagittal reformations of volumetric inspiratory and expiratory high-resolution CT of the lung. Acad Radiol 2004; 11:1282-90. PubMed
  • Nishino M, Hatabu H. Volumetric expiratory high-resolution CT of the lung. Eur J Radiol 2004; 52:180-4. PubMed
  • Nishino M, Busch JM, Wei J, Barbaras L, Yam CS, Hatabu H. Use of personal digital assistants in diagnostic radiology resident education. Acad Radiol 2004; 11:1153-8. PubMed
  • Nishino M, Wolfe D, Yam CS, Larson M, Boiselle PM, Hatabu H. Comprehensive innovative solution for resident education using the Intranet Journal of Chest Radiology. Acad Radiol 2004; 11:1149-52. PubMed
  • Itoh H, Nishino M, Hatabu H. Architecture of the lung: morphology and function. J Thorac Imaging 2004; 19:221-7. PubMed
  • Busch JM, Barbaras L, Wei J, Nishino M, Yam CS, Hatabu H. A mobile solution: PDA-based platform for radiology information management. AJR Am J Roentgenol 2004; 183:237-42. PubMed
  • Nishino M, Hayakawa K, Iwasaku K, Togashi K, Ueda H, Sago T, Noguchi M. MR imaging of ovarian hemorrhage. Eur J Radiol 2004; 51:34-40. PubMed
  • Nishino M, Kuroki M, Boiselle PM, Copeland JF, Raptopoulos V, Hatabu H. Coronal reformations of volumetric expiratory high-resolution CT of the lung. AJR Am J Roentgenol 2004; 182:979-82. PubMed
  • Nakayama T, Nishino M, Takasu K, Hayakawa K, Toguchida J, Tanaka C. Endovascular papillary angioendothelioma (Dabska tumor) of bone. Orthopedics 2004; 27:327-8. PubMed
  • Nishino M, Hayakawa K, Nakamura Y, Morimoto T, Mukaihara S. Effects of tamoxifen on hepatic fat content and the development of hepatic steatosis in patients with breast cancer: high frequency of involvement and rapid reversal after completion of tamoxifen therapy. AJR Am J Roentgenol 2003; 180:129-34. PubMed
  • Nishino M, Siewert B, Roberts DH, Gautam S, Boiselle PM, Raptopoulos V, Hatabu H. Excessive collapsibility of bronchi in bronchiectasis: evaluation on volumetric expiratory high-resolution CT. J Comput Assist Tomogr ; 30:474-8. PubMed
  • Tirumani SH, Fairchild A, Krajewski KM, Nishino M, Howard SA, Baheti AD, Rosenthal MH, Jagannathan JP, Shinagare AB, Ramaiya NH. Anti-VEGF molecular targeted therapies in common solid malignancies: comprehensive update for radiologists. Radiographics ; 35:455-74. PubMed
  • Tirumani SH, Kim KW, Nishino M, Howard SA, Krajewski KM, Jagannathan JP, Cleary JM, Ramaiya NH, Shinagare AB. Update on the role of imaging in management of metastatic colorectal cancer. Radiographics ; 34:1908-28. PubMed
  • Nishino M, Hayakawa K, Kawamata K, Iwasaku K, Takasu K. MRI of early unruptured ectopic pregnancy: detection of gestational sac. J Comput Assist Tomogr ; 26:134-7. PubMed
  • Kubo T, Nishino M, Kino A, Yoshimura N, Lin PJ, Takahashi M, Raptopoulos V, Hatabu H. 3-dimensional adaptive raw-data filter: evaluation in low dose chest multidetector-row computed tomography. J Comput Assist Tomogr ; 30:933-8. PubMed
  • Nishino M, Ashiku SK, Kocher ON, Thurer RL, Boiselle PM, Hatabu H. The thymus: a comprehensive review. Radiographics ; 26:335-48. PubMed
  • Nishino M, Hayakawa K, Minami M, Yamamoto A, Ueda H, Takasu K. Primary retroperitoneal neoplasms: CT and MR imaging findings with anatomic and pathologic diagnostic clues. Radiographics ; 23:45-57. PubMed
  • Nishino M, Kubo T, Kataoka ML, Gautam S, Raptopoulos V, Hatabu H. Evaluation of pulmonary embolisms using coronal reformations on 64-row multidetector-row computed tomography: Comparison with axial images. J Comput Assist Tomogr ; 30:233-7. PubMed
  • Nishino M, Hayakawa K, Iwasaku K, Takasu K. Magnetic resonance imaging findings in gynecologic emergencies. J Comput Assist Tomogr ; 27:564-70. PubMed
  • Nishino M, Hayakawa K, Yamamoto A, Nakamura Y, Morimoto T, Mukaihara S, Urata Y. Multiple enhancing lesions detected on dynamic helical computed tomography-mammography. J Comput Assist Tomogr ; 27:771-8. PubMed
  • Miyake K, Hayakawa K, Nishino M, Nakamura Y, Morimoto T, Urata Y, Ueda H, Tanikake M, Kanao S, Shiozaki T, Yamamoto A. Benign or malignant?: differentiating breast lesions with computed tomography attenuation values on dynamic computed tomography mammography. J Comput Assist Tomogr ; 29:772-9. PubMed
  • Nishino M, Boiselle PM, Copeland JF, Raptopoulos V, Hatabu H. Value of volumetric data acquisition in expiratory high-resolution computed tomography of the lung. J Comput Assist Tomogr ; 28:209-14. PubMed
  • Braschi-Amirfarzan M, Tirumani SH, Hodi FS, Nishino M. Immune-Checkpoint Inhibitors in the Era of Precision Medicine: What Radiologists Should Know. Korean J Radiol ; 18:42-53. PubMed
  • Nishino M, Hatabu H, Sholl LM, Ramaiya NH. Thoracic Complications of Precision Cancer Therapies: A Practical Guide for Radiologists in the New Era of Cancer Care. Radiographics ; 37:1371-1387. PubMed
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DF/HCC members that share similar concepts* with Mizuki Nishino, MD, MPH but have yet to coauthor a publication with this researcher.

* Concepts are MeSH terms, automatically derived from member publications

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