Photo of Laura S. Dominici, MD

Laura S. Dominici, MD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 632-3521


ldominici@partners.org

Photo of Laura S. Dominici, MD

Brigham And Women's Hospital
Phone: (617) 632-3521


ldominici@partners.org

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Laura S. Dominici, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Associate Professor, Surgery, Harvard Medical School
  • Breast Surgical Oncologist , Medical Oncology, Dana-Farber Cancer Institute
  • Surgical Oncologist , Faulkner Breast Center, Brigham And Women's Hospital

HCC PROGRAM AFFILIATION

Research Abstract

I am a breast surgical oncologist at the Brigham and Women's Hospital, Brigham and Women's Faulkner Hospital and Dana Farber Cancer Institute. My interests are local control as related to tumor biology, neoadjuvant chemotherapy response in breast cancer, patient satisfaction outcomes after breast surgery and innovative surgical techniques for treatment of breast disease.

Publications from Harvard Catalyst Profiles

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  • Laws A, Lagendijk M, Grossmith S, Hughes M, Lin NU, Mittendorf EA, Eliassen AH, King TA, Dominici LS. Long-Term Patient-Reported Arm Symptoms in Breast Cancer Survivors. Ann Surg Oncol 2023. PubMed
  • Wilson JM, Colebaugh CA, Flowers KM, Edwards RR, Partridge AH, Dominici LS, Schreiber KL. Early postoperative psychological distress as a mediator of subsequent persistent postsurgical pain outcomes among younger breast cancer patients. Breast Cancer Res Treat 2022; 196:363-370. PubMed
  • Lyu HG, Kantor O, Laws AD, McDonald J, Pham L, Dominici LS, Vincuilla J, Raut CP, Danilchuk B, Novak L, Parker T, King TA, Mittendorf EA. Development of an Electronic Health Record Registry to Facilitate Collection of Commission on Cancer Metrics for Patients Undergoing Surgery for Breast Cancer. JCO Clin Cancer Inform 2022; 6:e2200012. PubMed
  • Weiss A, King C, Vincuilla J, Parker T, Portnow L, Nakhlis F, Dominici L, Mittendorf EA, King TA. Rates of pathologic nodal disease among cN0 and cN1 patients undergoing routine axillary ultrasound and neoadjuvant chemotherapy. Breast Cancer Res Treat 2022; 195:181-189. PubMed
  • Tesch ME, Rosenberg SM, Collins LC, Wong JS, Dominici L, Ruddy KJ, Tamimi R, Schapira L, Borges VF, Warner E, Come SE, Partridge AH. Clinicopathologic Features, Treatment Patterns, and Disease Outcomes in a Modern, Prospective Cohort of Young Women Diagnosed with Ductal Carcinoma In Situ. Ann Surg Oncol 2022. PubMed
  • Broyles JM, Balk EM, Adam GP, Cao W, Bhuma MR, Mehta S, Dominici LS, Pusic AL, Saldanha IJ. Implant-based versus Autologous Reconstruction after Mastectomy for Breast Cancer: A Systematic Review and Meta-analysis. Plast Reconstr Surg Glob Open 2022; 10:e4180. PubMed
  • Saldanha IJ, Broyles JM, Adam GP, Cao W, Bhuma MR, Mehta S, Pusic AL, Dominici LS, Balk EM. Autologous Reconstruction after Mastectomy for Breast Cancer. Plast Reconstr Surg Glob Open 2022; 10:e4181. PubMed
  • Saldanha IJ, Broyles JM, Adam GP, Cao W, Bhuma MR, Mehta S, Pusic AL, Dominici LS, Balk EM. Implant-based Breast Reconstruction after Mastectomy for Breast Cancer: A Systematic Review and Meta-analysis. Plast Reconstr Surg Glob Open 2022; 10:e4179. PubMed
  • Tsangaris E, Edelen M, Means J, Gregorowitsch M, O'Gorman J, Pattanaik R, Dominici L, Hassett M, Witkowski ML, Schrieber K, Frank E, Carnie M, Pusic A. User-centered design and agile development of a novel mobile health application and clinician dashboard to support the collection and reporting of patient-reported outcomes for breast cancer care. BMJ Surg Interv Health Technol 2022; 4:e000119. PubMed
  • Nagra NS, Tsangaris E, Means J, Hassett MJ, Dominici LS, Bellon JR, Broyles J, Kaplan RS, Feeley TW, Pusic AL. Time-Driven Activity-Based Costing in Breast Cancer Care Delivery. Ann Surg Oncol 2021. PubMed
  • Kuijer A, Dominici LS, Rosenberg SM, Hu J, Gelber S, Di Lascio S, Wong JS, Ruddy KJ, Tamimi RM, Schapira L, Borges VF, Come SE, Sprunck-Harrild K, Partridge AH, King TA. Arm Morbidity After Local Therapy for Young Breast Cancer Patients. Ann Surg Oncol 2021. PubMed
  • Johnson AE, Coopey SB, Spring LM, Horick NK, Leone JP, Lin NU, Dominici LS, Hughes KS, Jimenez RB. Management and outcomes of men diagnosed with primary breast cancer. Breast Cancer Res Treat 2021. PubMed
  • Minami CA, Freedman RA, Karamourtopoulos M, Pinheiro A, Gilliam E, Aliberti G, Pories SE, Recht A, Lotz M, Dominici LS, Schonberg MA. Acceptability of a patient decision aid for women aged 70 and older with stage I, estrogen receptor-positive, HER2-negative breast cancer. 2021. PubMed
  • Dominici L, Hu J, Zheng Y, Kim HJ, King TA, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Warner E, Wong JS, Partridge AH, Rosenberg SM. Association of Local Therapy With Quality-of-Life Outcomes in Young Women With Breast Cancer. JAMA Surg 2021; 156:e213758. PubMed
  • Kim HJ, Dominici L, Rosenberg SM, Zheng Y, Pak LM, Poorvu PD, Ruddy KJ, Tamimi R, Schapira L, Come SE, Peppercorn J, Borges VF, Warner E, Vardeh H, Collins LC, Gaither R, King TA, Partridge AH. Surgical Treatment after Neoadjuvant Systemic Therapy in Young Women with Breast Cancer: Results from a Prospective Cohort Study. Ann Surg 2020. PubMed
  • Rosenberg SM, Dominici LS, Gelber S, Poorvu PD, Ruddy KJ, Wong JS, Tamimi RM, Schapira L, Come S, Peppercorn JM, Borges VF, Partridge AH. Association of Breast Cancer Surgery With Quality of Life and Psychosocial Well-being in Young Breast Cancer Survivors. JAMA Surg 2020. PubMed
  • Lagendijk M, Desantis S, Nakhlis F, Duggan M, Calvillo KZ, Carty M, Chun Y, Caterson S, Golshan M, Dominici LS. Impact of surgical complications on patient reported outcomes (PROs) following nipple sparing mastectomy. Am J Surg 2020. PubMed
  • Dominici LS, Rosenberg SM. Ductal carcinoma in situ (DCIS): The importance of patient-reported outcomes (PRO). Curr Breast Cancer Rep 2020; 12:90-97. PubMed
  • Lagendijk M, Mittendorf E, King TA, Gibbons C, Pusic A, Dominici LS. Incorporating Patient-Reported Outcome Measures into Breast Surgical Oncology: Advancing Toward Value-Based Care. Oncologist 2019. PubMed
  • Bowen DJ, Shinn EH, Gregrowski S, Kimmick G, Dominici LS, Frank ES, Smith KL, Rocque G, Ruddy KJ, Pollastro T, Melisko M, Ballinger TJ, Fayanju OM, Wolff AC. Patient-reported outcomes in the Translational Breast Cancer Research Consortium. Cancer 2019. PubMed
  • Berry DL, Blonquist TM, Halpenny B, Hong F, Morrison-Ma SC, McCullough MC, Carelli K, Dominici LS, King TA. The Jacki Jacket after mastectomy with reconstruction: a randomized pilot study. Breast Cancer Res Treat 2019. PubMed
  • Freund KM, Haas JS, Lemon SC, Burns White K, Casanova N, Dominici LS, Erban JK, Freedman RA, James TA, Ko NY, LeClair AM, Moy B, Parsons SK, Battaglia TA. Standardized activities for lay patient navigators in breast cancer care: Recommendations from a citywide implementation study. Cancer 2019. PubMed
  • Nakhlis F, Regan MM, Chun YS, Dominici LS, Caterson S, Bellon JR, Warren L, Yeh ED, Jacene HA, King TA, Overmoyer B. Patterns of breast reconstruction in patients diagnosed with inflammatory breast cancer: The Dana-Farber Cancer Institute's Inflammatory Breast Cancer Program experience. Breast J 2019. PubMed
  • Wong SM, Almana N, Choi J, Hu J, Gagnon H, Natsuhara K, Shen AH, DeSantis S, Dominici L, Golshan M, Weiss A, Bellon J, Mittendorf EA, King TA. Prognostic Significance of Residual Axillary Nodal Micrometastases and Isolated Tumor Cells After Neoadjuvant Chemotherapy for Breast Cancer. Ann Surg Oncol 2019. PubMed
  • Laws A, Hughes ME, Hu J, Barry WT, Dominici L, Nakhlis F, Barbie T, Duggan M, Weiss A, Rhei E, Carter K, Nimbkar S, Schnitt SJ, King TA. Impact of Residual Nodal Disease Burden on Technical Outcomes of Sentinel Lymph Node Biopsy for Node-Positive (cN1) Breast Cancer Patients Treated with Neoadjuvant Chemotherapy. Ann Surg Oncol 2019. PubMed
  • Schonberg MA, Freedman RA, Recht AR, Jacobson AR, Aliberti GM, Karamourtopoulos M, Nakhlis F, McCarthy EP, Pories SE, Sharma R, Dominici LS. Developing a patient decision aid for women aged 70 and older with early stage, estrogen receptor positive, HER2 negative, breast cancer. 2019. PubMed
  • Ligibel JA, Dillon D, Giobbie-Hurder A, McTiernan A, Frank E, Cornwell M, Pun M, Campbell N, Dowling RJO, Chang MC, Tolaney S, Chagpar AB, Yung RL, Freedman RA, Dominici LS, Golshan M, Rhei E, Taneja K, Huang Y, Brown M, Winer EP, Jeselsohn R, Irwin ML. Impact of a Pre-Operative Exercise Intervention on Breast Cancer Proliferation and Gene Expression: Results from the Pre-Operative Health and Body (PreHAB) Study. Clin Cancer Res 2019. PubMed
  • Schreiber KL, Zinboonyahgoon N, Xu X, Spivey T, King T, Dominici L, Partridge A, Golshan M, Strichartz G, Edwards RR. Preoperative Psychosocial and Psychophysical Phenotypes as Predictors of Acute Pain Outcomes after Breast Surgery. J Pain 2018. PubMed
  • Spivey TL, Gutowski ED, Zinboonyahgoon N, King TA, Dominici L, Edwards RR, Golshan M, Schreiber KL. Chronic Pain After Breast Surgery: A Prospective, Observational Study. Ann Surg Oncol 2018; 25:2917-2924. PubMed
  • Laws A, Anderson K, Hu J, McLean K, Novak L, Dominici LS, Nakhlis F, Carty M, Caterson S, Chun Y, Duggan M, Barry W, Connell N, Golshan M, King TA. Implementation of a Venous Thromboembolism Prophylaxis Protocol Using the Caprini Risk Assessment Model in Patients Undergoing Mastectomy. Ann Surg Oncol 2018. PubMed
  • Grossmith S, Nguyen A, Hu J, Plichta JK, Nakhlis F, Cutone L, Dominici L, Golshan M, Duggan M, Carter K, Rhei E, Barbie T, Calvillo K, Nimbkar S, Bellon J, Wong J, Punglia R, Barry W, King TA. Multidisciplinary Management of the Axilla in Patients with cT1-T2 N0 Breast Cancer Undergoing Primary Mastectomy: Results from a Prospective Single-Institution Series. Ann Surg Oncol 2018. PubMed
  • Dominici LS, Sineshaw HM, Jemal A, Lin CC, King TA, Freedman RA. Patterns of axillary evaluation in older patients with breast cancer and associations with adjuvant therapy receipt. Breast Cancer Res Treat 2017. PubMed
  • Nakhlis F, Regan MM, Warren LE, Bellon JR, Hirshfield-Bartek J, Duggan MM, Dominici LS, Golshan M, Jacene HA, Yeh ED, Mullaney EE, Overmoyer B. The Impact of Residual Disease After Preoperative Systemic Therapy on Clinical Outcomes in Patients with Inflammatory Breast Cancer. Ann Surg Oncol 2017. PubMed
  • Nurudeen S, Guo H, Chun Y, Coopey S, Barry W, Garber J, Dominici LS. Patient experience with breast reconstruction process following bilateral mastectomy in BRCA mutation carriers. Am J Surg 2017. PubMed
  • Nash R, Goodman M, Lin CC, Freedman RA, Dominici LS, Ward K, Jemal A. State Variation in the Receipt of a Contralateral Prophylactic Mastectomy Among Women Who Received a Diagnosis of Invasive Unilateral Early-Stage Breast Cancer in the United States, 2004-2012. JAMA Surg 2017. PubMed
  • Dominici LS, Morrow M, Mittendorf E, Bellon J, King TA. Trends and controversies in multidisciplinary care of the patient with breast cancer. Curr Probl Surg 2016; 53:559-595. PubMed
  • Caragacianu DL, Mayer EL, Chun YS, Caterson S, Bellon JR, Wong JS, Troyan S, Rhei E, Dominici LS, Economy KE, Tung NM, Schapira L, Partridge A, Calvillo KZ. Immediate breast reconstruction following mastectomy in pregnant women with breast cancer. J Surg Oncol 2016. PubMed
  • Mayer EL, Dominici LS. Breast cancer axillary staging: much ado about micrometastatic disease. J Clin Oncol 2015; 33:1095-7. PubMed
  • Son BH, Dominici LS, Aydogan F, Shulman LN, Ahn SH, Cho JY, Coopey SB, Kim SB, Min HE, Valero M, Wang J, Caragacianu D, Gong GY, Hevelone ND, Baek S, Golshan M. Young women with breast cancer in the United States and South Korea: comparison of demographics, pathology and management. Asian Pac. J. Cancer Prev. 2015; 16:2531-5. PubMed
  • Gropper AB, Calvillo KZ, Dominici L, Troyan S, Rhei E, Economy KE, Tung NM, Schapira L, Meisel JL, Partridge AH, Mayer EL. Sentinel lymph node biopsy in pregnant women with breast cancer. Ann Surg Oncol 2014. PubMed
  • Schubart JR, Dominici LS, Farnan M, Kelly TA, Manahan ER, Rahman ER, Smith JS, Kass RB. Shared decision making in breast cancer: national practice patterns of surgeons. Ann Surg Oncol 2013; 20:3323-9. PubMed
  • Dominici L, Liao GS, Brock J, Iglehart JD, Lotfi P, Meyer J, Pandalai P, Golshan M. Large needle core biopsy of atypical ductal hyperplasia: results of surgical excision. Breast J 2012. PubMed
  • Dominici LS, Lester S, Liao GS, Guo L, Specht M, Smith BL, Golshan M. Current surgical approach to Paget's disease. Am J Surg 2012. PubMed
  • Dominici LS, Mittendorf EA, Wang X, Liu J, Kuerer HM, Hunt KK, Brewster A, Babiera GV, Buchholz TA, Meric-Bernstam F, Bedrosian I. Implications of constructed biologic subtype and its relationship to locoregional recurrence following mastectomy. Breast Cancer Res 2012; 14:R82. PubMed
  • Dominici L, Najita J, Hughes M, Niland J, Marcom P, Wong YN, Carter B, Javid S, Edge S, Burstein H, Golshan M. Surgery of the primary tumor does not improve survival in stage IV breast cancer. Breast Cancer Res Treat 2011; 129:459-65. PubMed
  • Dominici LS, Mittendorf EA, Kuerer HM. Reply to Cytologically proven axillary lymph node metastases are eradicated in patients receiving preoperative chemotherapy with concurrent trastuzumab for HER2-positive breast cancer. Cancer 2010. PubMed
  • Dominici LS, Negron Gonzalez VM, Buzdar AU, Lucci A, Mittendorf EA, Le-Petross HT, Babiera GV, Meric-Bernstam F, Hunt KK, Kuerer HM. Cytologically proven axillary lymph node metastases are eradicated in patients receiving preoperative chemotherapy with concurrent trastuzumab for HER2-positive breast cancer. Cancer 2010; 116:2884-9. PubMed
  • Dominici LS, Kuerer HM, Babiera G, Hahn KM, Perkins G, Middleton L, Ramirez MM, Yang W, Hortobagyi GN, Theriault RL, Litton JK. Wound Complications from Surgery in Pregnancy-Associated Breast Cancer (PABC). Breast Dis 2010. PubMed
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Similar Members

HCC members that share similar concepts* with Laura S. Dominici, MD but have yet to coauthor a publication with this researcher.

* Concepts are MeSH terms, automatically derived from member publications

Similar Members