Photo of Scott R. Granter, MD

Scott R. Granter, MD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 732-7510
Fax: (617) 278-6901


sgranter@partners.org

Photo of Scott R. Granter, MD

Brigham And Women's Hospital
Phone: (617) 732-7510
Fax: (617) 278-6901


sgranter@partners.org

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Scott R. Granter, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Associate Pathologist, Pathology, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

Dr. Granter is a recognized expert in the area of dermatopathology, including diagnostic clinical (human) pathology and morphologic analysis of various models of melanoma pathogenesis. He has an established track record in the use of immunohistochemical analysis of neoplasia in humans and in animal models. His work has yielded insights into the pathobiology of cutaneous disease as well as established the clinical utility of immunohistochemical markers for diagnosis. In addition, Dr Granter is an active mentor for junior faculty and fellows through which he fosters learning and critical thinking.

Publications from Harvard Catalyst Profiles

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  • Dewan AK, Gupta S, Bach DQ, Jadeja S, Granter S, LaCasce A, Joyce R, Davids MS, Huang V, LeBoeuf NR. Psoriasiform eruptions secondary to phosphoinositide 3-kinase inhibition. JAAD Case Rep 2019; 5:401-405. PubMed
  • Pohthipornthawat N, Feldman S, Granter SR, Laga AC, Crum CP, Herfs M. Epidermodysplasia Verruciformis-like HPV infection of the Vulva in Immunosuppressed Women. Int J Gynecol Pathol 2017. PubMed
  • Bae GH, Kurtzman D, Granter SR, Vleugels RA, Nambudiri VE. Asymptomatic papules after breast cancer treatment. J Am Acad Dermatol 2017; 76:e157-e158. PubMed
  • Bae GH, Kurtzman D, Granter SR, Vleugels RA, Nambudiri VE. Asymptomatic papules after breast cancer treatment. J Am Acad Dermatol 2017; 76:e157-e158. PubMed
  • Lee JJ, Vilain RE, Granter SR, Hu NR, Bresler SC, Xu S, Frank AH, Mihm MC, Saw RP, Fletcher CD, Scolyer RA, Murphy GF, Lian CG. 5-Hydroxymethylcytosine is a Nuclear Biomarker to Assess Biological Potential in Histologically Ambiguous Heavily Pigmented Melanocytic Neoplasms. J Cutan Pathol 2016. PubMed
  • Ibrahim N, Buchbinder EI, Granter SR, Rodig SJ, Giobbie-Hurder A, Becerra C, Tsiaras A, Gjini E, Fisher DE, Hodi FS. A phase I trial of panobinostat (LBH589) in patients with metastatic melanoma. Cancer Med 2016; 5:3041-3050. PubMed
  • Davids MS, Kim HT, Bachireddy P, Costello C, Liguori R, Savell A, Lukez AP, Avigan D, Chen YB, McSweeney P, LeBoeuf NR, Rooney MS, Bowden M, Zhou CW, Granter SR, Hornick JL, Rodig SJ, Hirakawa M, Severgnini M, Hodi FS, Wu CJ, Ho VT, Cutler C, Koreth J, Alyea EP, Antin JH, Armand P, Streicher H, Ball ED, Ritz J, Bashey A, Soiffer RJ, . Ipilimumab for Patients with Relapse after Allogeneic Transplantation. N Engl J Med 2016; 375:143-53. PubMed
  • Bresler SC, Padwa BL, Granter SR. Nevoid Basal Cell Carcinoma Syndrome (Gorlin Syndrome). Head Neck Pathol 2016; 10:119-24. PubMed
  • Guo Y, Dreier JR, Cao J, Du H, Granter SR, Kwiatkowski DJ. Analysis of a Mouse Skin Model of Tuberous Sclerosis Complex. PLoS ONE 2016; 11:e0167384. PubMed
  • Luo C, Lim JH, Lee Y, Granter SR, Thomas A, Vazquez F, Widlund HR, Puigserver P. A PGC1α-mediated transcriptional axis suppresses melanoma metastasis. Nature 2016; 537:422-426. PubMed
  • Larson AR, Laga AC, Granter SR. The Spectrum of Histopathologic Findings in Cutaneous Lesions in Patients With Still Disease. Am J Clin Pathol 2015; 144:945-51. PubMed
  • Larson AR, Rodig S, Granter SR. Duration of symptoms does not correlate with results of T-cell gene rearrangement studies in patients evaluated for cutaneous T-cell lymphoma. J Cutan Pathol 2015. PubMed
  • Tse JY, Walls BE, Pomerantz H, Yoon CH, Buchbinder EI, Werchniak AE, Dong F, Lian CG, Granter SR. Melanoma arising in a nevus of Ito: novel genetic mutations and a review of the literature on cutaneous malignant transformation of dermal melanocytosis. J Cutan Pathol 2015. PubMed
  • Larson AR, Rothschild B, Walls AC, Granter SR, Qureshi AA, Murphy GF, Laga AC. Impact of the 2009 AJCC staging guidelines for melanoma on the number of mitotic figures reported by dermatopathologists at one institution. J Cutan Pathol 2015. PubMed
  • Nyame TT, Mattos D, Lian CG, Granter SR, Laga AC, Caterson EJ. Malignant Eccrine Spiradenoma of the Face. J Craniofac Surg 2015; 26:1711-2. PubMed
  • Mullangi S, Granter SR, Laubach JP, Lipworth AD. Scleromyxedema with histology resembling granuloma annulare. Dermatol Online J 2015. PubMed
  • Wang HX, Sharma C, Knoblich K, Granter SR, Hemler ME. EWI-2 negatively regulates TGF-β signaling leading to altered melanoma growth and metastasis. Cell Res 2015; 25:370-85. PubMed
  • Lee JJ, Granter SR, Laga AC, Saavedra AP, Zhan Q, Guo W, Xu S, Murphy GF, Lian CG. 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. Mod Pathol 2015. PubMed
  • Lee JJ, Sholl LM, Lindeman NI, Granter SR, Laga AC, Shivdasani P, Chin G, Luke JJ, Ott PA, Hodi FS, Mihm MC, Lin JY, Werchniak AE, Haynes HA, Bailey N, Liu R, Murphy GF, Lian CG. Targeted next-generation sequencing reveals high frequency of mutations in epigenetic regulators across treatment-naïve patient melanomas. Clin Epigenetics 2015; 7:59. PubMed
  • Larson AR, Cibas ES, Granter SR, Laga AC. Uncovering bias in the cytologic evaluation of cervical squamous lesions. Am J Clin Pathol 2015; 143:143-8. PubMed
  • Dadras SS, Lin RJ, Razavi G, Kawakami A, Du J, Feige E, Milner DA, Loda MF, Granter SR, Detmar M, Widlund HR, Horstmann MA, Fisher DE. A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression. Am J Pathol 2015; 185:252-65. PubMed
  • Kraft S, Granter SR. Molecular pathology of skin neoplasms of the head and neck. Arch Pathol Lab Med 2014; 138:759-87. PubMed
  • Lian CG, Bueno EM, Granter SR, Laga AC, Saavedra AP, Lin WM, Susa JS, Zhan Q, Chandraker AK, Tullius SG, Pomahac B, Murphy GF. Biomarker evaluation of face transplant rejection: association of donor T cells with target cell injury. Mod Pathol 2014. PubMed
  • Laga AC, Milner DA, Granter SR. Utility of acid-fast staining for detection of mycobacteria in cutaneous granulomatous tissue reactions. Am J Clin Pathol 2014; 141:584-6. PubMed
  • Nambudiri VE, Aboutalebi A, Granter SR, Saavedra A. Recurrent ALK-negative anaplastic large T-cell lymphoma presenting as necrotizing vasculitis. Am J Dermatopathol 2013. PubMed
  • Vazquez F, Lim JH, Chim H, Bhalla K, Girnun G, Pierce K, Clish CB, Granter SR, Widlund HR, Spiegelman BM, Puigserver P. PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. Cancer Cell 2013; 23:287-301. PubMed
  • Lilly E, Granter SR, Haynes HA, Ibrahimi OA. Chemotherapy-induced inflammatory seborrheic keratoses in a man with acute myeloid leukemia: a variant of Leser-Trélat sign? Cutis 2012; 90:235-6. PubMed
  • White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, Granter S, Young RA, Morrison S, Wheeler GN, Zon LI. DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature 2011; 471:518-22. PubMed
  • Levy C, Khaled M, Iliopoulos D, Janas MM, Schubert S, Pinner S, Chen PH, Li S, Fletcher AL, Yokoyama S, Scott KL, Garraway LA, Song JS, Granter SR, Turley SJ, Fisher DE, Novina CD. Intronic miR-211 Assumes the Tumor Suppressive Function of Its Host Gene in Melanoma. Mol Cell 2010; 40:841-849. PubMed
  • Kabbarah O, Nogueira C, Feng B, Nazarian RM, Bosenberg M, Wu M, Scott KL, Kwong LN, Xiao Y, Cordon-Cardo C, Granter SR, Ramaswamy S, Golub T, Duncan LM, Wagner SN, Brennan C, Chin L. Integrative genome comparison of primary and metastatic melanomas. PLoS ONE 2010; 5:e10770. PubMed
  • Zheng B,Jeong JH,Asara JM,Yuan YY,Granter SR,Chin L,Cantley LC. Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation. Mol Cell 2009; 33:237-47. PubMed
  • Cui R, Widlund HR, Feige E, Lin JY, Wilensky DL, Igras VE, D'Orazio J, Fung CY, Schanbacher CF, Granter SR, Fisher DE. Central role of p53 in the suntan response and pathologic hyperpigmentation. Cell 2007; 128:853-64. PubMed
  • D'Orazio JA, Nobuhisa T, Cui R, Arya M, Spry M, Wakamatsu K, Igras V, Kunisada T, Granter SR, Nishimura EK, Ito S, Fisher DE. Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning. Nature 2006; 443:340-4. PubMed
  • Kim M, Gans JD, Nogueira C, Wang A, Paik JH, Feng B, Brennan C, Hahn WC, Cordon-Cardo C, Wagner SN, Flotte TJ, Duncan LM, Granter SR, Chin L. Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell 2006; 125:1269-81. PubMed
  • Davis IJ, Kim JJ, Ozsolak F, Widlund HR, Rozenblatt-Rosen O, Granter SR, Du J, Fletcher JA, Denny CT, Lessnick SL, Linehan WM, Kung AL, Fisher DE. Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers. Cancer Cell 2006; 9:473-84. PubMed
  • Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, Fisher DE, Sellers WR. Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature 2005; 436:117-22. PubMed
  • Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, Zon LI. BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Curr Biol 2005; 15:249-54. PubMed
  • Nishimura EK, Granter SR, Fisher DE. Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche. Science 2005; 307:720-4. PubMed
  • Granter SR, Weilbaecher KN, Quigley C, Fisher DE. Role for microphthalmia transcription factor in the diagnosis of metastatic malignant melanoma. Appl Immunohistochem Mol Morphol 2002; 10:47-51. PubMed
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Visualize Collaborations
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DF/HCC members that share similar concepts* with Scott R. Granter, MD but have yet to coauthor a publication with this researcher.

* Concepts are MeSH terms, automatically derived from member publications

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