Photo of Brian V. Nahed,  MD MSc FAANS FACS

Brian V. Nahed, MD MSc FAANS FACS

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 724-5805
Fax: (617) 724-5806


bnahed@partners.org

Brian V. Nahed, MD MSc FAANS FACS

Massachusetts General Hospital

EDUCATIONAL TITLES

  • Associate Professor, Neurosurgery, Harvard Medical School
  • Program Director, Neurosurgery Residency Program, Neurosurgery, Massachusetts General Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

Dr. Brian Nahed is a neurosurgeon specializing in brain tumors (glioblastoma, gliomas (low grade and high grade), metastatic brain tumors, and meningiomas) as well as Spinal Disorders. Dr. Nahed specializes in brain tumors of the eloquent cortex (language and motor areas of the brain) which require awake surgery, language and motor mapping, and subcortical stimulation.

Born in New York, Dr. Nahed attended UCLA where he majored in Neuroscience, graduating Phi Beta Kappa and with the department's Highest Honors. He attended the Yale School of Medicine where he was awarded the Doris Duke Clinical Research Fellowship and graduated with honors. Dr. Nahed completed his internship and neurosurgery residency at the Massachusetts General Hospital; where Dr. Nahed also completed a postdoctoral fellowship with Drs. Daniel Haber and Shyamala Maheswaran in the MGH Cancer Center.

Dr. Brian Nahed was recruited to the MGH Department of Neurosurgery and Brain Tumor Center in 2011. As an Associate Professor at Harvard Medical School, Dr. Brian Nahed's research focuses on developing the first blood based test to diagnose and monitor brain tumors. In collaboration with Drs. Haber, Maheswaran, and Stott, Dr. Nahed recently published the first evidence of circulating tumor cells in the blood of patients with glioma. Dr. Nahed is actively enrolling patients into his translational clinical research study.

Dr. Brian Nahed serves as the Director of the MGH Neurosurgery Residency Program. He serves on the Executive Committee of the Congress of Neurological Surgeons and the CNS/AANS section on Tumors. He is an active member of the American Association of Neurological Surgeons and Council State Neurological Societies. Dr. Nahed is focused on education and socioeconomic issues in neurosurgery. He also serves as a neurotrauma consultant for the National Football League (NFL).

Publications from Harvard Catalyst Profiles

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  • Scarpetti L, Oturkar CC, Juric D, Shellock M, Malvarosa G, Post K, Isakoff S, Wang N, Nahed B, Oh K, Das GM, Bardia A. Therapeutic Role of Tamoxifen for Triple-Negative Breast Cancer: Leveraging the Interaction Between ERβ and Mutant p53. Oncologist 2023. PubMed
  • Alvarez-Breckenridge C, Markson SC, Stocking JH, Nayyar N, Lastrapes M, Strickland MR, Kim AE, de Sauvage M, Dahal A, Larson JM, Mora JL, Navia AW, Klein RH, Kuter BM, Gill CM, Bertalan M, Shaw B, Kaplan A, Subramanian M, Jain A, Kumar S, Danish H, White M, Shahid O, Pauken KE, Miller BC, Frederick DT, Hebert C, Shaw M, Martinez-Lage M, Frosch M, Wang N, Gerstner E, Nahed BV, Curry WT, Carter B, Cahill DP, Boland GM, Izar B, Davies MA, Sharpe AH, Suva ML, Sullivan RJ, Brastianos PK, Carter SL. Microenvironmental landscape of human melanoma brain metastases in response to immune checkpoint inhibition. Cancer Immunol Res 2022. PubMed
  • Gerritsen JKW, Broekman MLD, De Vleeschouwer S, Schucht P, Jungk C, Krieg SM, Nahed BV, Berger MS, Vincent AJPE. Global comparison of awake and asleep mapping procedures in glioma surgery: An international multicenter survey. Neurooncol Pract 2022; 9:123-132. PubMed
  • Gerritsen JKW, Broekman MLD, De Vleeschouwer S, Schucht P, Jungk C, Krieg SM, Nahed BV, Berger MS, Vincent AJPE. Decision making and surgical modality selection in glioblastoma patients: an international multicenter survey. J. Neurooncol. 2022; 156:465-482. PubMed
  • Mahajan A, Shih H, Penas-Prado M, Ligon K, Aldape K, Hu LS, Loughan AR, Basso MR, Leeper HE, Nahed BV, Stott SL, Geyer S, Giannini C, Galanis E. The Alliance AMBUSH Trial: Rationale and Design. Cancers (Basel) 2022. PubMed
  • Ng PR, Choi BD, Aghi MK, Nahed BV. Surgical advances in the management of brain metastases. 2021; 3:v4-v15. PubMed
  • Srinivasan ES, Grabowski MM, Nahed BV, Barnett GH, Fecci PE. Laser interstitial thermal therapy for brain metastases. 2021; 3:v16-v25. PubMed
  • Schupper AJ, Baron RB, Cheung W, Rodriguez J, Kalkanis SN, Chohan MO, Andersen BJ, Chamoun R, Nahed BV, Zacharia BE, Kennedy J, Moulding HD, Zucker L, Chicoine MR, Olson JJ, Jensen RL, Sherman JH, Zhang X, Price G, Fowkes M, Germano IM, Carter BS, Hadjipanayis CG, Yong RL. 5-Aminolevulinic acid for enhanced surgical visualization of high-grade gliomas: a prospective, multicenter study. J Neurosurg 2021. PubMed
  • Zaki MM, Mashouf LA, Woodward E, Langat P, Gupta S, Dunn IF, Wen PY, Nahed BV, Bi WL. Genomic landscape of gliosarcoma: distinguishing features and targetable alterations. Sci Rep 2021; 11:18009. PubMed
  • Khalafallah AM, Rakovec M, Bettegowda C, Jackson CM, Gallia GL, Weingart JD, Lim M, Esquenazi Y, Zacharia BE, Goldschmidt E, Ziu M, Ivan ME, Venteicher AS, Nduom EK, Mamelak AN, Chu RM, Yu JS, Sheehan JP, Nahed BV, Carter BS, Berger MS, Sawaya R, Mukherjee D. A Crowdsourced Consensus on Supratotal Resection Versus Gross Total Resection for Anatomically Distinct Primary Glioblastoma. Neurosurgery 2021. PubMed
  • Gerritsen JKW, Dirven CMF, De Vleeschouwer S, Schucht P, Jungk C, Krieg SM, Nahed BV, Berger MS, Broekman MLD, Vincent AJPE. The PROGRAM study: awake mapping versus asleep mapping versus no mapping for high-grade glioma resections: study protocol for an international multicenter prospective three-arm cohort study. BMJ Open 2021; 11:e047306. PubMed
  • Simon MV, Curry WT, Jones PS, Cahill DP, Carter BS, Rapalino O, Malik AN, Nahed BV. Intraoperative thalamocortical tract monitoring via direct cortical recordings during craniotomy. Clin Neurophysiol 2021; 132:1416-1432. PubMed
  • Gupta M, Burns E, Georgantas NZ, Thierauf J, Nayyar N, Gordon A, Jones S, Pisapia M, Sun Y, Burns RP, Velarde JK, Jordan JT, Frigault MJ, Nahed BV, Jones PS, Barker FG, Curry W, Gupta R, Batchelor TT, Romero J, Brastianos P, Marble H, Martinez-Lage M, Tateishi K, Lennerz JK, Dietrich J, Cahill D, Carter B, Shankar GM. A Rapid Genotyping Panel for Detection of Primary Central Nervous System Lymphoma. Blood 2021. PubMed
  • Redjal N, Venteicher AS, Dang D, Sloan A, Kessler RA, Baron RR, Hadjipanayis CG, Chen CC, Ziu M, Olson JJ, Nahed BV. Guidelines in the management of CNS tumors. J. Neurooncol. 2021; 151:345-359. PubMed
  • Muralidharan K, Yekula A, Small JL, Rosh ZS, Kang KM, Wang L, Lau S, Zhang H, Lee H, Bettegowda C, Chicoine MR, Kalkanis SN, Shankar GM, Nahed BV, Curry WT, Jones PS, Cahill DP, Balaj L, Carter BS. Promoter Mutation Analysis for Blood-Based Diagnosis and Monitoring of Gliomas. Clin Cancer Res 2021; 27:169-178. PubMed
  • Brastianos PK, Strickland MR, Lee EQ, Wang N, Cohen JV, Chukwueke U, Forst DA, Eichler A, Overmoyer B, Lin NU, Chen WY, Bardia A, Juric D, Dagogo-Jack I, White MD, Dietrich J, Nayyar N, Kim AE, Alvarez-Breckenridge C, Mahar M, Mora JL, Nahed BV, Jones PS, Shih HA, Gerstner ER, Giobbie-Hurder A, Carter SL, Oh K, Cahill DP, Sullivan RJ. Phase II study of ipilimumab and nivolumab in leptomeningeal carcinomatosis. Nat Commun 2021; 12:5954. PubMed
  • Redjal N, Nahed BV, Dietrich J, Kalkanis SN, Olson JJ. Congress of neurological surgeons systematic review and evidence-based guidelines update on the role of chemotherapeutic management and antiangiogenic treatment of newly diagnosed glioblastoma in adults. J. Neurooncol. 2020; 150:165-213. PubMed
  • Starkweather CK, Choi BD, Alvarez-Breckenridge C, Brastianos PK, Oh K, Wang N, Shih H, Nahed BV. Initial Approach to the Patient with Multiple Newly Diagnosed Brain Metastases. Neurosurg Clin N Am 2020; 31:505-513. PubMed
  • Brastianos PK, Lee EQ, Cohen JV, Tolaney SM, Lin NU, Wang N, Chukwueke U, White MD, Nayyar N, Kim A, Alvarez-Breckenridge C, Krop I, Mahar MK, Bertalan MS, Shaw B, Mora JL, Goss N, Subramanian M, Nayak L, Dietrich J, Forst DA, Nahed BV, Batchelor TT, Shih HA, Gerstner ER, Moy B, Lawrence D, Giobbie-Hurder A, Carter SL, Oh K, Cahill DP, Sullivan RJ. Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis. Nat Med 2020. PubMed
  • Gupta S, Hulsbergen AFC, Segar DJ, Hauser BM, Bernstock JD, Nazarian RM, Lawrence DP, Nahed BV, Broekman MLD, Smith TR. Central nervous system invading eccrine gland carcinoma: a clinicopathological case series and literature review. World Neurosurg 2020. PubMed
  • Alvarez-Breckenridge C, Nahed BV. In Reply: Congress of Neurological Surgeons Systematic Review and Evidence-Based Practice Guidelines on the Role of Surgery in the Management of Adults With Metastatic Brain Tumors. Neurosurgery 2019; 85:E618. PubMed
  • Choi BD, Yu X, Castano AP, Bouffard AA, Schmidts A, Larson RC, Bailey SR, Boroughs AC, Frigault MJ, Leick MB, Scarfò I, Cetrulo CL, Demehri S, Nahed BV, Cahill DP, Wakimoto H, Curry WT, Carter BS, Maus MV. CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity. Nat Biotechnol 2019; 37:1049-1058. PubMed
  • Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, Druck N, Rodman C, Dionne D, Kaplan A, Bertalan MS, Small J, Pelton K, Becker S, Bonal D, Nguyen QD, Servis RL, Fung JM, Mylvaganam R, Mayr L, Gojo J, Haberler C, Geyeregger R, Czech T, Slavc I, Nahed BV, Curry WT, Carter BS, Wakimoto H, Brastianos PK, Batchelor TT, Stemmer-Rachamimov A, Martinez-Lage M, Frosch MP, Stamenkovic I, Riggi N, Rheinbay E, Monje M, Rozenblatt-Rosen O, Cahill DP, Patel AP, Hunter T, Verma IM, Ligon KL, Louis DN, Regev A, Bernstein BE, Tirosh I, Suvà ML. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell 2019; 178:835-849.e21. PubMed
  • Bell JS, Koffie RM, Rattani A, Dewan MC, Baticulon RE, Qureshi MM, Wahjoepramono EJ, Rosseau G, Park K, Nahed BV. Global incidence of brain and spinal tumors by geographic region and income level based on cancer registry data. J Clin Neurosci 2019. PubMed
  • Dineen J, Maus DC, Muzyka I, See RB, Cahill DP, Carter BS, Curry WT, Jones PS, Nahed BV, Peterfreund RA, Simon MV. Factors that modify the risk of intraoperative seizures triggered by electrical stimulation during supratentorial functional mapping. Clin Neurophysiol 2019. PubMed
  • Elder JB, Nahed BV, Linskey ME, Olson JJ. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Role of Emerging and Investigational Therapties for the Treatment of Adults With Metastatic Brain Tumors. Neurosurgery 2019; 84:E201-E203. PubMed
  • Ammirati M, Nahed BV, Andrews D, Chen CC, Olson JJ. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on Treatment Options for Adults With Multiple Metastatic Brain Tumors. Neurosurgery 2019; 84:E180-E182. PubMed
  • Nahed BV, Alvarez-Breckenridge C, Brastianos PK, Shih H, Sloan A, Ammirati M, Kuo JS, Ryken TC, Kalkanis SN, Olson JJ. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Role of Surgery in the Management of Adults With Metastatic Brain Tumors. Neurosurgery 2019; 84:E152-E155. PubMed
  • Chongsathidkiet P, Jackson C, Koyama S, Loebel F, Cui X, Farber SH, Woroniecka K, Elsamadicy AA, Dechant CA, Kemeny HR, Sanchez-Perez L, Cheema TA, Souders NC, Herndon JE, Coumans JV, Everitt JI, Nahed BV, Sampson JH, Gunn MD, Martuza RL, Dranoff G, Curry WT, Fecci PE. Author Correction: Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors. Nat Med 2019; 25:529. PubMed
  • Arrillaga-Romany I, Curry WT, Jordan JT, Cahill DP, Nahed BV, Martuza RL, Loeffler JS, Järhult SJ, Muzikansky A, Cohen AB, Singhal AB, Goldstein JN, Batchelor TT. Performance of a Hospital Pathway for Patients With a New Single Brain Mass. J Oncol Pract 2019; 15:e211-e218. PubMed
  • Karsy M, Park MS, Bekelis K, Braca JA, Nahed BV, Colen CB, Barbaro NM, Berger MS, Mukherjee D. Commentary: Deficiencies in Socioeconomic Training During Neurosurgical Training. Neurosurgery 2019; 84:E79-E85. PubMed
  • Choi BD, Lee DK, Yang JC, Ayinon CM, Lee CK, Maus D, Carter BS, Barker FG, Jones PS, Nahed BV, Cahill DP, See RB, Simon MV, Curry WT. Receptor tyrosine kinase gene amplification is predictive of intraoperative seizures during glioma resection with functional mapping. J Neurosurg 2019. PubMed
  • Chongsathidkiet P, Jackson C, Koyama S, Loebel F, Cui X, Farber SH, Woroniecka K, Elsamadicy AA, Dechant CA, Kemeny HR, Sanchez-Perez L, Cheema TA, Souders NC, Herndon JE, Coumans JV, Everitt JI, Nahed BV, Sampson JH, Gunn MD, Martuza RL, Dranoff G, Curry WT, Fecci PE. Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors. Nat Med 2018; 24:1459-1468. PubMed
  • Babu MA, Nahed BV, Heary RF. Commentary: Prescription Drug Monitoring Programs and the Neurosurgeon: Impact on Workflow and Overall Perceptions. Neurosurgery 2018. PubMed
  • Lee DK, Fedorenko E, Simon MV, Curry WT, Nahed BV, Cahill DP, Williams ZM. Neural encoding and production of functional morphemes in the posterior temporal lobe. Nat Commun 2018; 9:1877. PubMed
  • Zachariah M, Oliveira-Costa JP, Carter B, Stott SL, Nahed BV. Blood-Based Biomarkers for the Diagnosis and Monitoring of Gliomas. 2018. PubMed
  • Reátegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Nat Commun 2018; 9:175. PubMed
  • Dabek RJ, Baletic N, McUmber H, Nahed B, Haynes A, Eberlin KR, Bojovic B. Development of a primary melanoma in situ within a full-thickness skin graft overlying a free muscle flap: a case report. Case Reports Plast Surg Hand Surg 2018; 5:23-26. PubMed
  • Shankar GM, Balaj L, Stott SL, Nahed B, Carter BS. Liquid biopsy for brain tumors. Expert Rev Mol Diagn 2017; 17:943-947. PubMed
  • Venteicher AS, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin MG, Hovestadt V, Escalante LE, Shaw ML, Rodman C, Gillespie SM, Dionne D, Luo CC, Ravichandran H, Mylvaganam R, Mount C, Onozato ML, Nahed BV, Wakimoto H, Curry WT, Iafrate AJ, Rivera MN, Frosch MP, Golub TR, Brastianos PK, Getz G, Patel AP, Monje M, Cahill DP, Rozenblatt-Rosen O, Louis DN, Bernstein BE, Regev A, Suvà ML. Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq. Science 2017. PubMed
  • Patel NV, Mian M, Stafford RJ, Nahed BV, Willie JT, Gross RE, Danish SF. Laser Interstitial Thermal Therapy Technology, Physics of Magnetic Resonance Imaging Thermometry, and Technical Considerations for Proper Catheter Placement During Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy. Neurosurgery 2016; 79 Suppl 1:S8-S16. PubMed
  • Vaios EJ, Nahed BV, Muzikansky A, Fathi AT, Dietrich J. Bone marrow response as a potential biomarker of outcomes in glioblastoma patients. J Neurosurg 2016. PubMed
  • Xu LW, Li A, Swinney C, Babu M, Veeravagu A, Wolfe SQ, Nahed BV, Ratliff JK, . An assessment of data and methodology of online surgeon scorecards. J Neurosurg Spine 2016. PubMed
  • Babu MA, Heary RF, Nahed BV. Does the Open Payments Database Provide Sunshine on Neurosurgery? Neurosurgery 2016. PubMed
  • Venteicher AS, Tirosh I, Hebert C, Escalante L, Martuza RL, Nahed BV, Curry WT, Cahill DP, Bernstein B, Louis DN, Regev A, Suva M. 142 Genetic and Nongenetic Determinants of Cellular Architecture in IDH1-Mutant Oligodendrogliomas and Astrocytomas Using Single-Cell Transcriptome Analysis. Neurosurgery 2016; 63 Suppl 1:158. PubMed
  • Redjal N, Reinshagen C, Le A, Walcott BP, McDonnell E, Dietrich J, Nahed BV. Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide. J. Neurooncol. 2016; 127:505-14. PubMed
  • Barber SR, Remenschneider AK, Kozin ED, Cunnane ME, Nahed BV, Leslie-Mazwi T, Quesnel AM. Cochlear Implantation in a Patient With Pfeiffer Syndrome and Temporal Bone Vascular Anomalies. Otol. Neurotol. 2016; 37:241-3. PubMed
  • Brastianos PK, Shankar GM, Gill CM, Taylor-Weiner A, Nayyar N, Panka DJ, Sullivan RJ, Frederick DT, Abedalthagafi M, Jones PS, Dunn IF, Nahed BV, Romero JM, Louis DN, Getz G, Cahill DP, Santagata S, Curry WT, Barker FG. Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy. Journal of the National Cancer Institute 2016. PubMed
  • Fathi AT, Nahed BV, Wander SA, Iafrate AJ, Borger DR, Hu R, Thabet A, Cahill DP, Perry AM, Joseph CP, Muzikansky A, Chi AS. Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma. Oncologist 2016; 21:214-9. PubMed
  • Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, Francis JM, Patel AA, Onozato ML, Riggi N, Livak KJ, Gennert D, Satija R, Nahed BV, Curry WT, Martuza RL, Mylvaganam R, Iafrate AJ, Frosch MP, Golub TR, Rivera MN, Getz G, Rozenblatt-Rosen O, Cahill DP, Monje M, Bernstein BE, Louis DN, Regev A, Suvà ML. Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma. Nature 2016. PubMed
  • Aghi MK, Nahed BV, Sloan AE, Ryken TC, Kalkanis SN, Olson JJ. The role of surgery in the management of patients with diffuse low grade glioma : A systematic review and evidence-based clinical practice guideline. J. Neurooncol. 2015; 125:503-30. PubMed
  • Nahed BV, Redjal N, Brat DJ, Chi AS, Oh K, Batchelor TT, Ryken TC, Kalkanis SN, Olson JJ. Management of patients with recurrence of diffuse low grade glioma : A systematic review and evidence-based clinical practice guideline. J. Neurooncol. 2015; 125:609-30. PubMed
  • Cahill DP, Sloan AE, Nahed BV, Aldape KD, Louis DN, Ryken TC, Kalkanis SN, Olson JJ. The role of neuropathology in the management of patients with diffuse low grade glioma : A systematic review and evidence-based clinical practice guideline. J. Neurooncol. 2015; 125:531-49. PubMed
  • Smith TR, Hulou MM, Yan SC, Cote DJ, Nahed BV, Babu MA, Das S, Gormley WB, Rutka JT, Laws ER, Heary RF. Defensive medicine in neurosurgery: the Canadian experience. J Neurosurg 2015. PubMed
  • Reinshagen C, Redjal N, Sajed DP, Nahed BV, Walcott BP. Intracranial dural based chondroma. J Clin Neurosci 2015. PubMed
  • Friedman GN, Grannan BL, Nahed BV, Codd PJ. Initial Experience with High-Definition Camera-On-a-Chip Flexible Endoscopy for Intraventricular Neurosurgery. World Neurosurg 2015. PubMed
  • Redjal N, Agarwalla PK, Dietrich J, Dinevski N, Stemmer-Rachamimov A, Nahed BV, Loeffler JS. Remote acute demyelination after focal proton radiation therapy for optic nerve meningioma. J Clin Neurosci 2015; 22:1367-9. PubMed
  • Shankar GM, Francis JM, Rinne ML, Ramkissoon SH, Huang FW, Venteicher AS, Akama-Garren EH, Kang YJ, Lelic N, Kim JC, Brown LE, Charbonneau SK, Golby AJ, Sekhar Pedamallu C, Hoang MP, Sullivan RJ, Cherniack AD, Garraway LA, Stemmer-Rachamimov A, Reardon DA, Wen PY, Brastianos PK, Curry WT, Barker FG, Hahn WC, Nahed BV, Ligon KL, Louis DN, Cahill DP, Meyerson M. Rapid Intraoperative Molecular Characterization of Glioma. JAMA Oncol 2015. PubMed
  • Girgis F, Walcott BP, Kwon CS, Sheth SA, Asaad W, Nahed BV, Eskandar EN, Coumans JV. The Absence of Fever or Leukocytosis Does Not Exclude Infection Following Cranioplasty. Can J Neurol Sci 2015; 42:255-9. PubMed
  • Smith TR, Habib A, Rosenow JM, Nahed BV, Babu MA, Cybulski G, Fessler R, Batjer HH, Heary RF. Defensive medicine in neurosurgery: does state-level liability risk matter? Neurosurgery 2015. PubMed
  • Sullivan JP, Nahed BV, Madden MW, Oliveira SM, Springer S, Bhere D, Chi AS, Wakimoto H, Rothenberg SM, Sequist LV, Kapur R, Shah K, Iafrate AJ, Curry WT, Loeffler JS, Batchelor TT, Louis DN, Toner M, Maheswaran S, Haber DA. Brain tumor cells in circulation are enriched for mesenchymal gene expression. 2014. PubMed
  • Yanamadala V, Walcott BP, Fecci PE, Rozman P, Kumar JI, Nahed BV, Swearingen B. Reversal of warfarin associated coagulopathy with 4-factor prothrombin complex concentrate in traumatic brain injury and intracranial hemorrhage. J Clin Neurosci 2014. PubMed
  • Coumans JV, Neal JB, Grottkau BE, Nahed BV, Shin JH, Walcott BP. Giant thoracic osteophyte: a distinct clinical entity. J Clin Neurosci 2014. PubMed
  • Walcott BP, Khanna A, Kwon CS, Phillips HW, Nahed BV, Coumans JV. Time interval to surgery and outcomes following the surgical treatment of acute traumatic subdural hematoma. J Clin Neurosci 2014. PubMed
  • Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science 2014. PubMed
  • Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, Beik S, Kadri S, Tirosh I, Wortman I, Shalek AK, Rozenblatt-Rosen O, Regev A, Louis DN, Bernstein BE. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell 2014; 157:580-94. PubMed
  • Forst DA, Nahed BV, Loeffler JS, Batchelor TT. Low-grade gliomas. Oncologist 2014; 19:403-13. PubMed
  • Shankar GM, Taylor-Weiner A, Lelic N, Jones RT, Kim JC, Francis JM, Abedalthagafi M, Borges LF, Coumans JV, Curry WT, Nahed BV, Shin JH, Paek SH, Park SH, Stewart C, Lawrence MS, Cibulskis K, Thorner AR, Van Hummelen P, Stemmer-Rachamimov AO, Batchelor TT, Carter SL, Hoang MP, Santagata S, Louis DN, Barker FG, Meyerson M, Getz G, Brastianos PK, Cahill DP. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathol Commun 2014; 2:167. PubMed
  • Walcott BP, Neal JB, Sheth SA, Kahle KT, Eskandar EN, Coumans JV, Nahed BV. The incidence of complications in elective cranial neurosurgery associated with dural closure material. J Neurosurg 2014; 120:278-84. PubMed
  • Hanak BW, Walcott BP, Nahed BV, Muzikansky A, Mian MK, Kimberly WT, Curry WT. Postoperative intensive care unit requirements after elective craniotomy. World Neurosurg 2014. PubMed
  • Strong C, Yanamadala V, Khanna A, Walcott BP, Nahed BV, Borges LF, Coumans JV. Surgical treatment options and management strategies of metastatic renal cell carcinoma to the lumbar spinal nerve roots. J Clin Neurosci 2013; 20:1546-9. PubMed
  • Venteicher AS, Walcott BP, Sheth SA, Snuderl M, Patel AP, Curry WT, Nahed BV. Clinical features of brain metastasis from salivary gland tumors. J Clin Neurosci 2013; 20:1533-7. PubMed
  • Walcott BP, Boehm KM, Stapleton CJ, Mehta BP, Nahed BV, Ogilvy CS. Retrievable stent thrombectomy in the treatment of acute ischemic stroke: analysis of a revolutionizing treatment technique. J Clin Neurosci 2013; 20:1346-9. PubMed
  • Ryu JH, Walcott BP, Kahle KT, Sheth SA, Peterson RT, Nahed BV, Coumans JV, Simard JM. Induced and sustained hypernatremia for the prevention and treatment of cerebral edema following brain injury. Neurocrit Care 2013. PubMed
  • Codd PJ, Agarwalla PK, Berry-Candelario J, Nahed BV. Kernohan-woltman notch phenomenon in acute subdural hematoma. JAMA Neurol 2013; 70:1194-5. PubMed
  • Awad AJ, Walcott BP, Stapleton CJ, Yanamadala V, Nahed BV, Coumans JV. Dabigatran, intracranial hemorrhage, and the neurosurgeon. Neurosurg Focus 2013; 34:E7. PubMed
  • Walcott BP, Kwon CS, Sheth SA, Fehnel CR, Koffie RM, Asaad WF, Nahed BV, Coumans JV. Predictors of cranioplasty complications in stroke and trauma patients. J Neurosurg 2013; 118:757-62. PubMed
  • Yanamadala V, Walcott BP, Nahed BV, Barker FG. Retrograde third ventriculocisternostomy from the posterior fossa. Neurosurgery 2013. PubMed
  • Cohen AB, Nahed BV, Sheth KN. Mobile medical applications in neurology. Neurol Clin Pract 2013; 3:52-60. PubMed
  • Walcott BP, Nahed BV, Brastianos PK, Loeffler JS. Radiation Treatment for WHO Grade II and III Meningiomas. 2013; 3:227. PubMed
  • Walcott BP, Nahed BV, Coumans JV. Helicopter vs ground transportation for patients with trauma. JAMA 2012; 308:564; author reply 565. PubMed
  • Babu MA, Nahed BV, Smith TR, Heary RF. 115 Differences in Defensive Practices between Neurosurgeons in Malpractice Crisis vs Non-Crisis States. Neurosurgery 2012; 71:E548. PubMed
  • Walcott BP, Nahed BV, Sheth SA, Yanamadala V, Caracci JR, Asaad WF. Bilateral hemicraniectomy in non-penetrating traumatic brain injury. 2012; 29:1879-85. PubMed
  • Mian MK, Nahed BV, Walcott BP, Ogilvy CS, Curry WT. Glioblastoma multiforme and cerebral cavernous malformations: intersection of pathophysiologic pathways. J Clin Neurosci 2012. PubMed
  • Walcott BP, Kahle KT, Nahed BV, Coumans JV, Asaad WF. The use of intra-operative blood gas analysis in the investigation of suspected iatrogenic vascular injury. Eur Spine J 2012; 21 Suppl 4:S492-4. PubMed
  • Castro B, Walcott BP, Redjal N, Coumans JV, Nahed BV. Cerebrospinal fluid fistula prevention and treatment following frontal sinus fractures: a review of initial management and outcomes. Neurosurg Focus 2012; 32:E1. PubMed
  • Walcott BP, Edlow BL, Xia Z, Kahle KT, Nahed BV, Schmahmann JD. Steroid responsive A3243G mutation MELAS: clinical and radiographic evidence for regional hyperperfusion leading to neuronal loss. Neurologist 2012; 18:159-70. PubMed
  • Babu MA, Heary RF, Nahed BV. Device innovation in neurosurgery: controversy, learning, and future directions. Neurosurgery 2012; 70:789-94; discussion 794-5. PubMed
  • Yanamadala V, Walcott BP, Nahed BV, Coumans JV. Delayed post-traumatic bilateral abducens nerve palsy with complete recovery. J Clin Neurosci 2012; 19:585-6. PubMed
  • Barnard ZR, Walcott BP, Kahle KT, Nahed BV, Coumans JV. Hyponatremia associated with Ipilimumab-induced hypophysitis. Med Oncol 2012; 29:374-7. PubMed
  • Mian MK, Nahed BV, Walcott BP, Coumans JV. Intraspinal migration of a clavicular Steinmann pin: case report and management strategy. J Clin Neurosci 2012; 19:310-3. PubMed
  • Walcott BP, Nahed BV, Mohyeldin A, Coumans JV, Kahle KT, Ferreira MJ. Chordoma: current concepts, management, and future directions. Lancet Oncol 2012; 13:e69-76. PubMed
  • Coumans JV, Walcott BP, Nahed BV, Oh KS, Chi AS. Multimodal therapy of an intramedullary cervical primitive neuroectodermal tumor in an adult. J Clin Oncol 2012; 30:e15-8. PubMed
  • Walcott BP, Nahed BV, Kahle KT, Sekhar LN, Ferreira MJ. Cerebrovascular bypass and aneurysm trapping for the treatment of an A2-segment anterior cerebral artery pseudoaneurysm and herniation through a skull base defect following trauma. J Clin Neurosci 2012; 19:149-51. PubMed
  • Ferreira M, Nahed BV, Babu MA, Walcott BP, Ellenbogen RG, Sekhar LN. Trapped fourth ventricle phenomenon following aneurysm rupture of the posterior circulation: case reports. Neurosurgery 2012; 70:E253-8; discussion E258. PubMed
  • Stapleton CJ, Walcott BP, Kahle KT, Codd PJ, Nahed BV, Chen L, Robison NJ, Delalle I, Goumnerova LC, Jackson EM. Diffuse central neurocytoma with craniospinal dissemination. J Clin Neurosci 2012; 19:163-6. PubMed
  • Walcott BP, Nahed BV, Sarpong Y, Kahle KT, Sekhar LN, Ferreira MJ. Incidence of cerebrospinal fluid leak following petrosectomy and analysis of avoidance techniques. J Clin Neurosci 2012; 19:92-4. PubMed
  • Nahed BV, Babu MA, Smith TR, Heary RF. Malpractice liability and defensive medicine: a national survey of neurosurgeons. PLoS ONE 2012; 7:e39237. PubMed
  • Walcott BP, Nahed BV, Kahle KT, Duhaime AC, Sharma N, Eskandar EN. Deep brain stimulation for medically refractory life-threatening status dystonicus in children. J Neurosurg Pediatrics 2012; 9:99-102. PubMed
  • Babu MA, Nahed BV, Heary RF. Investigating the scope of resident patient care handoffs within neurosurgery. PLoS ONE 2012; 7:e41810. PubMed
  • Walcott BP, Sheth SA, Nahed BV, Coumans JV. Conflict of interest in spine research reporting. PLoS ONE 2012; 7:e44327. PubMed
  • Bashinskaya B, Nahed BV, Walcott BP, Coumans JV, Onuma OK. Socioeconomic status correlates with the prevalence of advanced coronary artery disease in the United States. PLoS ONE 2012; 7:e46314. PubMed
  • Walcott BP, Nahed BV, Redjal N, Stein TD, Kahle KT, Coumans JV. Pathological mechanism of lumbar disc herniation resulting in neurogenic muscle hypertrophy. J Clin Neurosci 2011; 18:1682-4. PubMed
  • Bashinskaya B, Nahed BV, Redjal N, Kahle KT, Walcott BP. Trends in Peptic Ulcer Disease and the Identification of Helicobacter Pylori as a Causative Organism: Population-based Estimates from the US Nationwide Inpatient Sample. J Glob Infect Dis 2011; 3:366-70. PubMed
  • Walcott BP, Cvetanovich GL, Barnard ZR, Nahed BV, Kahle KT, Curry WT. Surgical treatment and outcomes of metastatic breast cancer to the spine. J Clin Neurosci 2011; 18:1336-9. PubMed
  • Pisapia JM, Walcott BP, Nahed BV, Kahle KT, Ogilvy CS. Cerebral revascularization for the treatment of complex intracranial aneurysms of the posterior circulation: microsurgical anatomy, techniques and outcomes. 2011; 3:249-54. PubMed
  • Coumans JV, Walcott BP, Butler WE, Nahed BV, Kahle KT. Volumetric analysis of syringomyelia following hindbrain decompression for Chiari malformation Type I: syringomyelia resolution follows exponential kinetics. Neurosurg Focus 2011; 31:E4. PubMed
  • Schanker BD, Walcott BP, Nahed BV, Kahle KT, Li YM, Coumans JV. Familial Chiari malformation: case series. Neurosurg Focus 2011; 31:E1. PubMed
  • Aghi MK, Walcott BP, Nahed BV, Cvetanovich GL, Kahle KT, Redjal N, Coumans JV. Determinants of initial bone graft volume loss in posterolateral lumbar fusion. J Clin Neurosci 2011; 18:1193-6. PubMed
  • Kahle KT, Walcott BP, Nahed BV, Barnard ZR, Lo EH, Buonanno FS, Venna N, Ning M. Cerebral edema and a transtentorial brain herniation syndrome associated with pandemic swine influenza A (H1N1) virus infection. J Clin Neurosci 2011; 18:1245-8. PubMed
  • Babu MA, Nahed BV, Demoya MA, Curry WT. Is trauma transfer influenced by factors other than medical need? An examination of insurance status and transfer in patients with mild head injury. Neurosurgery 2011; 69:659-67; discussion 667. PubMed
  • Naunheim MR, Walcott BP, Nahed BV, Simpson AK, Agarwalla PK, Coumans JV. The quality of randomized controlled trial reporting in spine literature. Spine 2011; 36:1326-30. PubMed
  • Walcott BP, Pisapia JM, Nahed BV, Kahle KT, Ogilvy CS. Early experience with flow diverting endoluminal stents for the treatment of intracranial aneurysms. J Clin Neurosci 2011; 18:891-4. PubMed
  • Stapleton CJ, Walcott BP, Linskey KR, Kahle KT, Nahed BV, Asaad WF. Temporal bone chondroblastoma with secondary aneurysmal bone cyst presenting as an intracranial mass with clinical seizure activity. J Clin Neurosci 2011; 18:857-60. PubMed
  • Hanak BW, Walcott BP, Codd PJ, Jones PS, Nahed BV, Butler WE, Asaad WF. Fourth ventricular neurocystercercosis presenting with acute hydrocephalus. J Clin Neurosci 2011; 18:867-9. PubMed
  • Schanker BD, Walcott BP, Nahed BV, Ogilvy CS, Kiruluta AJ, Rabinov JD, Copen WA. Time-resolved contrast-enhanced magnetic resonance angiography in the investigation of suspected intracranial dural arteriovenous fistula. J Clin Neurosci 2011; 18:837-9. PubMed
  • Babu MA, Rosenow JM, Nahed BV. Physician-owned hospitals, neurosurgeons, and disclosure: lessons from law and the literature. Neurosurgery 2011; 68:1724-32; discussion 1732. PubMed
  • Nahed BV, Ferreira M, Babu MA, Terry AR, Walcott BP, Kahle KT, Smith ER. Dural scalp and intracranial hemangiomas causing hydrocephalus and venous sinus thrombosis in an infant. J Child Neurol 2011; 26:777-81. PubMed
  • Ferreira M, Walcott BP, Nahed BV, Sekhar LN. Vertebral artery pexy for microvascular decompression of the facial nerve in the treatment of hemifacial spasm. J Neurosurg 2011; 114:1800-4. PubMed
  • Walcott BP, Nahed BV, Kahle KT, Redjal N, Coumans JV. Determination of geographic variance in stroke prevalence using Internet search engine analytics. Neurosurg Focus 2011; 30:E19. PubMed
  • Tubbs RS, Patel N, Nahed BV, Cohen-Gadol AA, Spinner RJ. Reflections on the contributions of Harvey Cushing to the surgery of peripheral nerves. J Neurosurg 2011; 114:1442-8. PubMed
  • Coumans JV, Walcott BP, Redjal N, Kahle KT, Nahed BV. En bloc excision of a dermal sinus tract. J Clin Neurosci 2011; 18:554-8. PubMed
  • Naunheim MR, Walcott BP, Nahed BV, MacRae CA, Levinson JR, Ogilvy CS. Arterial tortuosity syndrome with multiple intracranial aneurysms: a case report. Arch Neurol 2011; 68:369-71. PubMed
  • Walcott BP, Gerrard JL, Nogueira RG, Nahed BV, Terry AR, Ogilvy CS. Microsurgical retrieval of an endovascular microcatheter trapped during Onyx embolization of a cerebral arteriovenous malformation. 2011; 3:77-9. PubMed
  • Walcott BP, Kuklina EV, Nahed BV, George MG, Kahle KT, Simard JM, Asaad WF, Coumans JV. Craniectomy for malignant cerebral infarction: prevalence and outcomes in US hospitals. PLoS ONE 2011; 6:e29193. PubMed
  • Walcott BP, Hanak BW, Caracci JR, Redjal N, Nahed BV, Kahle KT, Coumans JV. Trends in inpatient setting laminectomy for excision of herniated intervertebral disc: Population-based estimates from the US nationwide inpatient sample. Surg Neurol Int 2011; 2:7. PubMed
  • Walcott BP, Coumans JV, Mian MK, Nahed BV, Kahle KT. Interfacility helicopter ambulance transport of neurosurgical patients: observations, utilization, and outcomes from a quaternary level care hospital. PLoS ONE 2011; 6:e26216. PubMed
  • Nogueira RG, Kasper E, Walcott BP, Nahed BV, Redjal N, Coumans JV, Hirsch JA. Lateral sacral artery aneurysm of the lumbar spine: hemorrhage resulting in cauda equina syndrome. 2010; 2:399-401. PubMed
  • Naunheim MR, Nahed BV, Walcott BP, Kahle KT, Soupir CP, Cahill DP, Borges LF. Diagnosis of acute lymphoblastic leukemia from intracerebral hemorrhage and blast crisis. A case report and review of the literature. Clin Neurol Neurosurg 2010; 112:575-7. PubMed
  • Asaad WF, Walcott BP, Nahed BV, Ogilvy CS. Operative management of brainstem cavernous malformations. Neurosurg Focus 2010; 29:E10. PubMed
  • Nahed BV, Walcott BP, Ortman AJ, Kahle KT, Aghi M, Peterfreund RA, Coumans JV. Interval, acute onset airway obstruction associated with a fracture of the C4 vertebra in a patient with ankylosing spondylitis. J Clin Neurosci 2010; 17:1085-8. PubMed
  • Kahle KT, Simard JM, Staley KJ, Nahed BV, Jones PS, Sun D. Molecular mechanisms of ischemic cerebral edema: role of electroneutral ion transport. Physiology (Bethesda) 2009; 24:257-65. PubMed
  • Nahed BV,Ferreira M,Naunheim MR,Kahle KT,Proctor MR,Smith ER. Intracranial vasospasm with subsequent stroke after traumatic subarachnoid hemorrhage in a 22-month-old child. J Neurosurg Pediatrics 2009; 3:311-5. PubMed
  • Nahed HA, Hoda AT, Yomna IM. Effects of garlic on albino mice experimentally infected with Schistosoma mansoni: a parasitological and ultrastructural study. Trop Biomed 2009; 26:40-50. PubMed
  • Voorhees JR, Tubbs RS, Nahed B, Cohen-Gadol AA. William S. Halsted and Harvey W. Cushing: reflections on their complex association. J Neurosurg 2009; 110:384-90. PubMed
  • Kahle KT, Staley KJ, Nahed BV, Gamba G, Hebert SC, Lifton RP, Mount DB. Roles of the cation-chloride cotransporters in neurological disease. Nat Clin Pract Neurol 2008; 4:490-503. PubMed
  • Nahed BV, Darbar A, Doiron R, Saad A, Robson CD, Smith ER. Acute hydrocephalus secondary to obstruction of the foramen of monro and cerebral aqueduct caused by a choroid plexus cyst in the lateral ventricle. Case report. J Neurosurg 2007; 107:236-9. PubMed
  • Nahed BV, Bydon M, Ozturk AK, Bilguvar K, Bayrakli F, Gunel M. Genetics of intracranial aneurysms. Neurosurgery 2007; 60:213-25; discussion 225-6. PubMed
  • Ozturk AK, Nahed BV, Bydon M, Bilguvar K, Goksu E, Bademci G, Guclu B, Johnson MH, Amar A, Lifton RP, Gunel M. Molecular genetic analysis of two large kindreds with intracranial aneurysms demonstrates linkage to 11q24-25 and 14q23-31. Stroke 2006; 37:1021-7. PubMed
  • Kasowski HJ, Nahed BV, Piepmeier JM. Transcallosal transchoroidal approach to tumors of the third ventricle. Neurosurgery 2005; 57:361-6; discussion 361-6. PubMed
  • Nahed BV, DiLuna ML, Morgan T, Ocal E, Hawkins AA, Ozduman K, Kahle KT, Chamberlain A, Amar AP, Gunel M. Hypertension, age, and location predict rupture of small intracranial aneurysms. Neurosurgery 2005; 57:676-83; discussion 676-83. PubMed
  • Cohen-Gadol AA, Nahed BV, Voorhees JR, Maher CO, Spencer DD. Cushing's experience with the surgical treatment of spinal dysraphism. J Neurosurg 2005; 102:441-4. PubMed
  • Nahed BV, Seker A, Guclu B, Ozturk AK, Finberg K, Hawkins AA, DiLuna ML, State M, Lifton RP, Gunel M. Mapping a Mendelian form of intracranial aneurysm to 1p34.3-p36.13. Am J Hum Genet 2005; 76:172-9. PubMed
  • Kozlowski DA, Nahed BV, Hovda DA, Lee SM. Paradoxical effects of cortical impact injury on environmentally enriched rats. 2004; 21:513-9. PubMed
  • Nahed AK, Hanan SA, Hanan MS, Laila AS, Fatma SM. The production and evaluation of a standard diagnostic peste des petits ruminants (PPR) hyperimmune serum prepared from the Egyptian antigen (Egypt 87). Egypt J Immunol 2004; 11:9-14. PubMed
  • Fineman I, Giza CC, Nahed BV, Lee SM, Hovda DA. Inhibition of neocortical plasticity during development by a moderate concussive brain injury. 2000; 17:739-49. PubMed
  • Dunn GP, Nahed BV, Walcott BP, Jung H, Tierney TS, Ogilvy CS. Dual ipsilateral craniotomies through a single incision for the surgical management of multiple intracranial aneurysms. World Neurosurg ; 77:502-6. PubMed
  • Ginat DT, Walcott BP, Mordes D, Schaefer PW, Nahed B. Intracranial organizing hematoma with papillary endothelial hyperplasia features after resection and involved field radiotherapy for cerebellar juvenile pilocytic astrocytoma. Clin Imaging ; 38:322-5. PubMed
  • Vaios EJ, Winter SF, Muzikansky A, Nahed BV, Dietrich J. Eosinophil and lymphocyte counts predict bevacizumab response and survival in recurrent glioblastoma. ; 2:vdaa031. PubMed
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