HCC Policy Updates Summary - Effective February 2026
February 26, 2026
Summary of Updates
MULTI-100: HCC Investigator-Sponsored Multi-Center Research
- Section 5.6.15. The requirement for use of the HCC Multi-Center Data and Safety Monitoring Plan Template has been revised to apply only to interventional trials involving a drug, device, biologic, radiation, or surgery (including surgical biopsies) that are determined to be greater than minimal risk, rather than to all interventional trials.
- “DF/HCC” updated to “HCC” throughout.
View a full summary of the updates, tracked changes, and additional guidance here: Summary of HCC Policy Updates 2/26/26. This summary is also available on the HCC Policy Updates page.
The updated policy is now available in the HCC Document Library.
Please contact ODQEducation@dfci.harvard.edu with any questions regarding this announcement.