Cancer Risk and Disparities Program

The DF/HCC Cancer Risk and Disparities Program supports research that will lead to a reduction of cancer risk and disparities across the lifespan. The Program’s role is to elucidate underlying reasons certain individuals and populations bear excess risk of cancer and to devise interventions to lower risk. 

The Program’s expanding research portfolio is distinguished in several domains: in the promulgation of a social-contextual framework of cancer risk; in reframing cancer risk determinants with a purview that spans the life course; in its contribution to understanding disparities in cancer risk across population groups; in the design, testing, implementation, and evaluation of innovative interventions to reduce cancer risk; and in its commitment to the science of knowledge translation and dissemination of research findings into sustainable community-based solutions. Although cancer disparities research is conducted within and across other programs, the establishment of a “home-base” in which more than 50 disparities investigators may collaborate, be mentored, and make inter-programmatic connections, added significant value to their research and careers, while maximizing impact within DF/HCC and the field.

Special Event

UMB-DF/HCC Partnership Cancer Symposium 2021

1:00PM Monday April 12, 2021

Talk Title: “Next Generation Cancer Therapeutics and Cancer Scientists”

Recent Publications

  • Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O, Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wucherpfennig JI, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, Unger B, Prokop JW, Heidel JR, Wang XX, Ukaegbu CI, Jennings BC, Paulo JA, Gableske S, Fierke CA, Getz G, Sunyaev SR, Wade Harper J, Cichowski K, Kimmelman AC, Houvras Y, Syngal S, Williams C, Goessling W. Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer. Nat Genet 2019; 51:1308-1314. PubMed
  • Irwin KE, Moy B, Fields LE, Callaway CA, Park ER, Wirth L. Expanding Access to Cancer Clinical Trials for Patients With Mental Illness. J Clin Oncol 2019; 37:1524-1528. PubMed
  • Butler S, Muralidhar V, Chavez J, Fullerton Z, Mahal A, Nezolosky M, Vastola M, Zhao SG, D'Amico AV, Dess RT, Feng FY, King MT, Mouw KW, Spratt DE, Trinh QD, Nguyen PL, Rebbeck TR, Mahal BA. Active Surveillance for Low-Risk Prostate Cancer in Black Patients. N Engl J Med 2019; 380:2070-2072. PubMed
  • Warner ET, Lathan CS. Race and sex differences in patient provider communication and awareness of lung cancer screening in the health information National Trends Survey, 2013-2017. Prev Med 2019; 124:84-90. PubMed
  • Nabi-Burza E, Regan S, Walters BH, Drehmer JE, Rigotti NA, Ossip DJ, Gorzkowski JA, Levy DE, Winickoff JP. Parental Dual Use of e-Cigarettes and Traditional Cigarettes. Acad Pediatr 2019. PubMed
  • Agénor M, Jahn JL, Kay E, Bishop RA, Peitzmeier SM, Potter J, Austin SB. Human Papillomavirus Risk Perceptions Among Young Adult Sexual Minority Cisgender Women and Nonbinary Individuals Assigned Female at Birth. Perspect Sex Reprod Health 2019; 51:27-34. PubMed
  • Drehmer JE, Nabi-Burza E, Hipple Walters B, Ossip DJ, Levy DE, Rigotti NA, Klein JD, Winickoff JP. Parental Smoking and E-cigarette Use in Homes and Cars. Pediatrics 2019. PubMed
  • Perez GK, Gareen IF, Sicks J, Lathan C, Carr A, Kumar P, Ponzani C, Hyland K, Park ER. Racial Differences in Smoking-related Disease Risk Perceptions Among Adults Completing Lung Cancer Screening: Follow-up Results from the ACRIN/NLST Ancillary Study. J Racial Ethn Health Disparities 2019. PubMed
  • Kahan S, Manson JE. Obesity Treatment, Beyond the Guidelines: Practical Suggestions for Clinical Practice. JAMA 2019. PubMed
  • Wharam JF, Zhang F, Wallace J, Lu C, Earle C, Soumerai SB, Nekhlyudov L, Ross-Degnan D. Vulnerable And Less Vulnerable Women In High-Deductible Health Plans Experienced Delayed Breast Cancer Care. Health Aff (Millwood) 2019; 38:408-415. PubMed
  • Percac-Lima S, Ashburner JM, Atlas SJ, Rigotti NA, Flores EJ, Kuchukhidze S, Park ER. Barriers to and Interest in Lung Cancer Screening Among Latino and Non-Latino Current and Former Smokers. J Immigrant Minority Health 2019. PubMed
  • Wang GX, Baggett TP, Pandharipande PV, Park ER, Percac-Lima S, Shepard JO, Fintelmann FJ, Flores EJ. Barriers to Lung Cancer Screening Engagement from the Patient and Provider Perspective. Radiology 2019; 290:278-287. PubMed
  • Charlton BM, Kahn JA, Sarda V, Katz-Wise SL, Spiegelman D, Missmer SA, Austin SB. Maternal Factors and Sexual Orientation-Related Disparities in Cervical Cancer Prevention. Womens Health Issues 2019. PubMed
  • Rauh-Hain JA, Hidrue MK, Gaccione P, Melamed A, Meyer LA, Keating NL, Giordano SH, Rice LW, Birrer MJ, Del Carmen MG. Variation in resource utilization associated with the surgical management of ovarian cancer. Gynecol Oncol 2018. PubMed
  • Gardecki JA, Singh K, Wu CL, Tearney GJ. Imaging the Human Prostate Gland Using 1-μm-Resolution Optical Coherence Tomography. Arch Pathol Lab Med 2018. PubMed
  • Ma Y, Yang W, Song M, Smith-Warner SA, Yang J, Li Y, Ma W, Hu Y, Ogino S, Hu FB, Wen D, Chan AT, Giovannucci EL, Zhang X. Type 2 diabetes and risk of colorectal cancer in two large U.S. prospective cohorts. Br J Cancer 2018; 119:1436-1442. PubMed
  • McCloud RF, Bekalu MA, Maddox N, Minsky SJ, Viswanath K. Leveraging breadth and depth: Strategies to characterize population diversity to address cancer disparities in the DF/HCC Catchment Area. Cancer Epidemiol Biomarkers Prev 2018. PubMed
  • Thorndike AN. E-Cigarette Use by Young Adult Nonsmokers: Next-Generation Nicotine Dependence? Ann Intern Med 2018. PubMed
  • Tabatabaei N, Kang D, Kim M, Wu T, Grant CN, Rosenberg M, Nishioka NS, Hesterberg PE, Garber J, Yuan Q, Katz AJ, Tearney GJ. Clinical Translation of Tethered Confocal Microscopy Capsule for Unsedated Diagnosis of Eosinophilic Esophagitis. Sci Rep 2018; 8:2631. PubMed
  • Cook EE, Venkataramani AS, Kim JJ, Tamimi RM, Holmes MD. Legislation to Increase Uptake of HPV Vaccination and Adolescent Sexual Behaviors. Pediatrics 2018. PubMed
  • Rebbeck TR, Burns-White K, Chan AT, Emmons K, Freedman M, Hunter DJ, Kraft P, Laden F, Mucci L, Parmigiani G, Schrag D, Syngal S, Tamimi RM, Viswanath K, Yurgelun MB, Garber JE. Precision Prevention and Early Detection of Cancer: Fundamental Principles. 2018. PubMed
  • Wharam JF, Zhang F, Lu CY, Wagner AK, Nekhlyudov L, Earle CC, Soumerai SB, Ross-Degnan D. Breast Cancer Diagnosis and Treatment After High-Deductible Insurance Enrollment. J Clin Oncol 2018; 36:1121-1127. PubMed
  • Rauh-Hain JA, Melamed A, Schaps D, Bregar AJ, Spencer R, Schorge JO, Rice LW, Del Carmen MG. Racial and ethnic disparities over time in the treatment and mortality of women with gynecological malignancies. Gynecol Oncol 2018; 149:4-11. PubMed
  • Cook EE, Gershman ST, Kim JJ, Tamimi RM, Klevens RM, Holmes MD. Trends of two HPV-associated cancers in Massachusetts: cervical and oropharyngeal cancer. Cancer Causes Control 2018. PubMed
  • Japuntich SJ, Kumar P, Pendergast J, Juarez Caballero GY, Malin J, Wallace R, Chrischilles E, Keating NL, Park ER. Smoking status and survival among a national cohort of lung and colorectal cancer patients. Nicotine Tob Res 2018. PubMed
  • Sharifi M, Franz C, Horan CM, Giles CM, Long MW, Ward ZJ, Resch SC, Marshall R, Gortmaker SL, Taveras EM. Cost-Effectiveness of a Clinical Childhood Obesity Intervention. Pediatrics 2017. PubMed
  • Rebbeck TR. Prostate Cancer Disparities by Race and Ethnicity: From Nucleotide to Neighborhood. Cold Spring Harb Perspect Med 2017. PubMed
  • Kirchhoff AC, Nipp R, Warner EL, Kuhlthau K, Leisenring WM, Donelan K, Rabin J, Perez GK, Oeffinger KC, Nathan PC, Robison LL, Armstrong GT, Park ER. "Job Lock" Among Long-term Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. JAMA Oncol 2017. PubMed
  • Luba DG, DiSario JA, Rock C, Saraiya D, Moyes K, Brown K, Rushton K, Ogara MM, Raphael M, Zimmerman D, Garrido K, Silguero E, Nelson J, Yurgelun MB, Kastrinos F, Wenstrup RJ, Syngal S. Community Practice Implementation of a Self-administered Version of PREMM1,2,6 to Assess Risk for Lynch Syndrome. Clin Gastroenterol Hepatol 2017. PubMed
  • Kim JJ, Burger EA, Sy S, Campos NG. Optimal Cervical Cancer Screening in Women Vaccinated Against Human Papillomavirus. Journal of the National Cancer Institute 2017; 109:1-9. PubMed
  • Campbell JD, Lathan C, Sholl L, Ducar M, Vega M, Sunkavalli A, Lin L, Hanna M, Schubert L, Thorner A, Faris N, Williams DR, Osarogiagbon RU, van Hummelen P, Meyerson M, MacConaill L. Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations. JAMA Oncol 2017. PubMed
  • Percac-Lima S, Ashburner JM, Zai AH, Chang Y, Oo SA, Guimaraes E, Atlas SJ. Patient Navigation for Comprehensive Cancer Screening in High-Risk Patients Using a Population-Based Health Information Technology System: A Randomized Clinical Trial. JAMA Intern Med 2016; 176:930-7. PubMed
  • Schmid M, Meyer CP, Reznor G, Choueiri TK, Hanske J, Sammon JD, Abdollah F, Chun FK, Kibel AS, Tucker-Seeley RD, Kantoff PW, Lipsitz SR, Menon M, Nguyen PL, Trinh QD. Racial Differences in the Surgical Care of Medicare Beneficiaries With Localized Prostate Cancer. JAMA Oncol 2015. PubMed
  • Freedman RA, Kouri EM, West DW, Keating NL. Racial/Ethnic Differences in Patients' Selection of Surgeons and Hospitals for Breast Cancer Surgery. JAMA Oncol 2015; 1:222-30. PubMed
  • Mahal BA, Ziehr DR, Aizer AA, Hyatt AS, Lago-Hernandez C, Choueiri TK, Elfiky AA, Hu JC, Sweeney CJ, Beard CJ, D'Amico AV, Martin NE, Kim SP, Lathan CS, Trinh QD, Nguyen PL. Racial disparities in an aging population: the relationship between age and race in the management of African American men with high-risk prostate cancer. 2014. PubMed
  • Dutra LM, Williams DR, Kawachi I, Okechukwu CA. Racial and non-racial discrimination and smoking status among South African adults 10 years after apartheid. Tobacco Control 2014. PubMed
  • Roberts AL, Rosario M, Calzo JP, Corliss HL, Frazier L, Austin SB. Masculine boys, feminine girls, and cancer risk behaviors: an 11-year longitudinal study. J Adolesc Health 2014. PubMed
  • Rigotti NA, Regan S, Levy DE, Japuntich S, Chang Y, Park ER, Viana JC, Kelley JH, Reyen M, Singer DE. Sustained care intervention and postdischarge smoking cessation among hospitalized adults: a randomized clinical trial. JAMA 2014; 312:719-28. PubMed
  • Krieger N, Kosheleva A, Waterman PD, Chen JT, Beckfield J, Kiang MV. 50-year trends in US socioeconomic inequalities in health: US-born Black and White Americans, 1959-2008. Int J Epidemiol 2014. PubMed
  • Mays D, DeMarco TA, Luta G, Peshkin BN, Patenaude AF, Schneider KA, Garber JE, Tercyak KP. Distress and the parenting dynamic among BRCA1/2 tested mothers and their partners. Health Psychol 2014. PubMed
  • Halonen JI, Kivimäki M, Pentti J, Stenholm S, Kawachi I, Subramanian SV, Vahtera J. Green and blue areas as predictors of overweight and obesity in an 8-year follow-up study. Obesity (Silver Spring) 2014. PubMed
  • Emmons KM, Puleo E, Greaney ML, Gillman MW, Bennett GG, Haines J, Sprunck-Harrild K, Viswanath K. A randomized comparative effectiveness study of Healthy Directions 2--a multiple risk behavior intervention for primary care. Prev Med 2014. PubMed
  • Blaine K, Rogers J, Winickoff JP, Oppenheimer SC, Timm A, Ozonoff A, Geller AC. Engaging in secondhand smoke reduction discussions with parents of hospitalized pediatric patients: a national survey of pediatric nurses in the United States. Prev Med 2014; 62:83-8. PubMed
  • Nimptsch K, Malik VS, Fung TT, Pischon T, Hu FB, Willett WC, Fuchs CS, Ogino S, Chan AT, Giovannucci E, Wu K. Dietary patterns during high school and risk of colorectal adenoma in a cohort of middle-aged women. Int J Cancer 2014; 134:2458-67. PubMed
  • Duncan DT, Kawachi I, Melly SJ, Blossom J, Sorensen G, Williams DR. Demographic disparities in the tobacco retail environment in Boston: a citywide spatial analysis. Public Health Rep 2014; 129:209-15. PubMed
  • Nelson CC, Wagner GR, Caban-Martinez AJ, Buxton OM, Kenwood CT, Sabbath EL, Hashimoto DM, Hopcia K, Allen J, Sorensen G. Physical activity and body mass index: the contribution of age and workplace characteristics. Am J Prev Med 2014; 46:S42-51. PubMed
  • Wright DR, Taveras EM, Gillman MW, Horan CM, Hohman KH, Gortmaker SL, Prosser LA. The cost of a primary care-based childhood obesity prevention intervention. BMC Health Serv Res 2014; 14:44. PubMed
  • Gortmaker SL, Taveras EM. Who becomes obese during childhood--clues to prevention. N Engl J Med 2014; 370:475-6. PubMed
  • Winickoff JP, Gottlieb M, Mello MM. Tobacco 21--an idea whose time has come. N Engl J Med 2014; 370:295-7. PubMed
  • Taveras EM, Marshall R, Horan CM, Gillman MW, Hacker K, Kleinman KP, Koziol R, Price S, Rifas-Shiman SL, Simon SR. Improving children's obesity-related health care quality: process outcomes of a cluster-randomized controlled trial. Obesity (Silver Spring) 2014; 22:27-31. PubMed
  • Traeger L, Cannon S, Keating NL, Pirl WF, Lathan C, Martin MY, He Y, Park ER. Race by sex differences in depression symptoms and psychosocial service use among non-Hispanic black and white patients with lung cancer. J Clin Oncol 2014; 32:107-13. PubMed
  • Ebbeling CB. Sugar-sweetened beverages and body weight. Curr. Opin. Lipidol. 2014; 25:1-7. PubMed
  • Viswanath K, McCloud R, Minsky S, Puleo E, Kontos E, Bigman-Galimore C, Rudd R, Emmons KM. Internet use, browsing, and the urban poor: implications for cancer control. J Natl Cancer Inst Monogr 2014; 2013:199-205. PubMed
  • Kim JJ, Sharma M, O'Shea M, Sweet S, Diaz M, Sancho-Garnier H, Seoud M. Model-based impact and cost-effectiveness of cervical cancer prevention in the Extended Middle East and North Africa (EMENA). Vaccine 2013; 31 Suppl 6:G65-77. PubMed
  • Sorensen G, McLellan D, Dennerlein JT, Pronk NP, Allen JD, Boden LI, Okechukwu CA, Hashimoto D, Stoddard A, Wagner GR. Integration of health protection and health promotion: rationale, indicators, and metrics. J Occup Environ Med 2013; 55:S12-8. PubMed
  • Percac-Lima S, Ashburner JM, Bond B, Oo SA, Atlas SJ. Decreasing disparities in breast cancer screening in refugee women using culturally tailored patient navigation. J Gen Intern Med 2013; 28:1463-8. PubMed
  • Sorensen G, Pednekar MS, Sinha DN, Stoddard AM, Nagler E, Aghi MB, Lando HA, Viswanath K, Pawar P, Gupta PC. Effects of a tobacco control intervention for teachers in India: results of the Bihar school teachers study. Am J Public Health 2013; 103:2035-40. PubMed
  • Slopen N, Kontos EZ, Ryff CD, Ayanian JZ, Albert MA, Williams DR. Psychosocial stress and cigarette smoking persistence, cessation, and relapse over 9-10 years: a prospective study of middle-aged adults in the United States. Cancer Causes Control 2013; 24:1849-63. PubMed
  • Sonneville KR, Rifas-Shiman SL, Haines J, Gortmaker S, Mitchell KF, Gillman MW, Taveras EM. Associations of parental control of feeding with eating in the absence of hunger and food sneaking, hiding, and hoarding. Child Obes 2013; 9:346-9. PubMed
  • Bogart LM, Cowgill BO, Sharma AJ, Uyeda K, Sticklor LA, Alijewicz KE, Schuster MA. Parental and home environmental facilitators of sugar-sweetened beverage consumption among overweight and obese Latino youth. Acad Pediatr 2013; 13:348-55. PubMed
  • Ramanadhan S, Viswanath K. Priority-setting for evidence-based health outreach in community-based organizations: A mixed-methods study in three Massachusetts communities. Transl Behav Med 2013; 3:180-188. PubMed